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{"title"=>"Aspiration-Related Acute Respiratory Distress Syndrome in Acute Stroke Patient", "type"=>"journal", "authors"=>[{"first_name"=>"Jiang-nan", "last_name"=>"Zhao"}, {"first_name"=>"Yao", "last_name"=>"Liu"}, {"first_name"=>"Huai-chen", "last_name"=>"Li"}], "year"=>2015, "source"=>"PLOS ONE", "identifiers"=>{"pmid"=>"25790377", "doi"=>"10.1371/journal.pone.0118682", "issn"=>"1932-6203"}, "id"=>"8a232813-fc1f-30f6-8d01-e617bf3d4b10", "abstract"=>"BACKGROUND: Aspiration of oral or gastric contents into the larynx and lower respiratory tract is a common problem in acute stroke patients, which significantly increases the incidence of acute respiratory distress syndrome (ARDS). However, little is known about the clinical characteristics of aspiration-related ARDS in acute stroke patients. METHODS: Over 17-month period a retrospective cohort study was done on 1495 consecutive patients with acute stroke. The data including demographic characteristics, clinical manifestations, laboratory examinations, chest imaging, and hospital discharge status were collected to analysis. RESULTS: Aspiration-related ARDS was diagnosed in 54 patients (3.6%). The most common presenting symptom was tachypnea (respiratory rate >/=25 breaths/min) in 50 cases. Computed tomography (CT) images usually demonstrated diffuse ground-glass opacities (GGOs) and inhomogeneous patchy consolidations involving the low lobes. Age, NIHSS score, GCS score, dysphagia, dysarthria, hemoglobin concentration, serum aspertate aminotransferase (AST), serum albumin, serum sodium, and admission glucose level were independently associated with aspiration-related ARDS (odds ratio (OR) 1.05, 95% confidence interval (CI) (1.04-1.07); OR 2.87, (2.68-3.63); OR 4.21, (3.57-5.09); OR 2.18, (1.23-3.86); OR 1.67, (1.31-2.14); OR 2.31, (1.11-4.84); OR 1.68, (1.01-2.80); OR 2.15, (1.19-3.90); OR 1.92, (1.10-3.36) and OR 1.14, (1.06-1.21) respectively). CONCLUSIONS: Aspiration-related ARDS frequently occurs in acute stroke patient with impairment consciousness. It is advisable that performing chest CT timely may identify disease early and prompt treatment to rescue patients.", "link"=>"http://www.mendeley.com/research/aspirationrelated-acute-respiratory-distress-syndrome-acute-stroke-patient", "reader_count"=>20, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Librarian"=>1, "Researcher"=>3, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>4, "Student > Master"=>4, "Other"=>3, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Librarian"=>1, "Researcher"=>3, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>4, "Student > Master"=>4, "Other"=>3, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Nursing and Health Professions"=>1, "Mathematics"=>1, "Medicine and Dentistry"=>11, "Neuroscience"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>2, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Neuroscience"=>{"Neuroscience"=>2}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>2}}, "group_count"=>2}

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• http://doi.org/10.3892/mmr.2017.7516
• http://doi.org/10.1080/15412555.2018.1464551

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/1963063"], "description"=>"<p>Abbreviation: SD, standard deviation; NIHSS, National Institutes of Health Stroke Scale; GCS, Glasgow Coma Scale; COPD, chronic obstructive pulmonary disease; AST, aspertate aminotransferase; WBC, white blood cell; LOS, length-of-stay.</p><p>Characteristics in the groups with aspiration-related ARDS and no pulmonary complication: results of univariate analysis.</p>", "links"=>[], "tags"=>["stroke patient", "50 cases", "serum aspertate aminotransferase", "serum sodium", "GCS score", "impairment consciousness", "retrospective cohort study", "stroke patients", "admission glucose level", "Computed tomography", "ast", "laboratory examinations", "chest imaging", "odds ratio", "GGO", "ci", "distress syndrome", "chest CT", "characteristic", "hemoglobin concentration", "NIHSS score", "rescue patients", "hospital discharge status", "ards", "Acute Stroke Patient BackgroundAspiration", "patchy consolidations"], "article_id"=>1344512, "categories"=>["Biological Sciences"], "users"=>["Jiang-nan Zhao", "Yao Liu", "Huai-chen Li"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0118682.t002", "stats"=>{"downloads"=>5, "page_views"=>27, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_in_the_groups_with_aspiration_related_ARDS_and_no_pulmonary_complication_results_of_univariate_analysis_/1344512", "title"=>"Characteristics in the groups with aspiration-related ARDS and no pulmonary complication: results of univariate analysis.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-03-19 04:59:39"}
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• {"files"=>["https://ndownloader.figshare.com/files/1963059"], "description"=>"<p>Radiologic finding in a 68-year-old acute stroke man with aspiration-related ARDS.</p>", "links"=>[], "tags"=>["stroke patient", "50 cases", "serum aspertate aminotransferase", "serum sodium", "GCS score", "impairment consciousness", "retrospective cohort study", "stroke patients", "admission glucose level", "Computed tomography", "ast", "laboratory examinations", "chest imaging", "odds ratio", "GGO", "ci", "distress syndrome", "chest CT", "characteristic", "hemoglobin concentration", "NIHSS score", "rescue patients", "hospital discharge status", "ards", "Acute Stroke Patient BackgroundAspiration", "patchy consolidations"], "article_id"=>1344508, "categories"=>["Biological Sciences"], "users"=>["Jiang-nan Zhao", "Yao Liu", "Huai-chen Li"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0118682.g001", "stats"=>{"downloads"=>1, "page_views"=>28, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Radiologic_finding_in_a_68_year_old_acute_stroke_man_with_aspiration_related_ARDS_/1344508", "title"=>"Radiologic finding in a 68-year-old acute stroke man with aspiration-related ARDS.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-03-19 04:59:39"}
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• {"files"=>["https://ndownloader.figshare.com/files/1963061"], "description"=>"<p>ROC curve to assess the discriminatory ability of the model predicting aspiration-related ARDS.</p>", "links"=>[], "tags"=>["stroke patient", "50 cases", "serum aspertate aminotransferase", "serum sodium", "GCS score", "impairment consciousness", "retrospective cohort study", "stroke patients", "admission glucose level", "Computed tomography", "ast", "laboratory examinations", "chest imaging", "odds ratio", "GGO", "ci", "distress syndrome", "chest CT", "characteristic", "hemoglobin concentration", "NIHSS score", "rescue patients", "hospital discharge status", "ards", "Acute Stroke Patient BackgroundAspiration", "patchy consolidations"], "article_id"=>1344510, "categories"=>["Biological Sciences"], "users"=>["Jiang-nan Zhao", "Yao Liu", "Huai-chen Li"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0118682.g003", "stats"=>{"downloads"=>1, "page_views"=>23, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_ROC_curve_to_assess_the_discriminatory_ability_of_the_model_predicting_aspiration_related_ARDS_/1344510", "title"=>"ROC curve to assess the discriminatory ability of the model predicting aspiration-related ARDS.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-03-19 04:59:39"}
• {"files"=>["https://ndownloader.figshare.com/files/1963062"], "description"=>"<p>Abbreviation: CPAP, continuous positive airway pressure; FiO₂, fraction of inspired oxygen; PaO₂, partial pressure of arterial oxygen; PEEP, positive eng-expiratory pressure.</p><p>^a Chest radiograph or computed tomography scan.</p><p>^b If altitude is higher than 1000m, the correction factor should be calculated as follows: [PaO₂/FiO₂ ×(barometric pressure/760)].</p><p>^c This may be delivered noninvasively in the mild acute respiratory distress syndrome group.</p><p>The Berlin definition of acute respiratory distress syndrome.</p>", "links"=>[], "tags"=>["stroke patient", "50 cases", "serum aspertate aminotransferase", "serum sodium", "GCS score", "impairment consciousness", "retrospective cohort study", "stroke patients", "admission glucose level", "Computed tomography", "ast", "laboratory examinations", "chest imaging", "odds ratio", "GGO", "ci", "distress syndrome", "chest CT", "characteristic", "hemoglobin concentration", "NIHSS score", "rescue patients", "hospital discharge status", "ards", "Acute Stroke Patient BackgroundAspiration", "patchy consolidations"], "article_id"=>1344511, "categories"=>["Biological Sciences"], "users"=>["Jiang-nan Zhao", "Yao Liu", "Huai-chen Li"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0118682.t001", "stats"=>{"downloads"=>4, "page_views"=>27, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_Berlin_definition_of_acute_respiratory_distress_syndrome_/1344511", "title"=>"The Berlin definition of acute respiratory distress syndrome.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-03-19 04:59:39"}

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Relative Metric

{"start_date"=>"2015-01-01T00:00:00Z", "end_date"=>"2015-12-31T00:00:00Z", "subject_areas"=>[]}

F1000Prime