How to Establish and Follow up a Large Prospective Cohort Study in the 21st Century - Lessons from UK COSMOS
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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/2163792"], "description"=>"<p>Legend: Blue bars represent Phase 2, red bars represent Phase 7. Fig 2 Footnotes: Phase 2 used a mobile phone subscriber sampling frame, letter invitation, web-based consent, registration, and questionnaire and a prize draw incentive, and recruited N = 67,793. Phase 7 used an electoral register sampling frame, letter invitation, web-based consent, registration, and questionnaire and a gift voucher incentive, and recruited N = 36,316. Together Phases 2 and 7 recruited N = 104,109. The profile of participants presented here is based on N = 67627 from Phase 2 and N = 36218 from Phase 7, i.e. excluding 264 withdrawals. With the exception of socio-economic classification, the percentages calculated exclude Missing from the denominator. N for missing are as follows: Phase 2: Sex N = 290, Age group N = 306, Ethnicity N = 9205, Highest Educational Qualification N = 9124, Smoking N = 8404; Phase 7: Sex N = 2, Age group N = 9, Ethnicity N = 5135, Highest Educational Qualification N = 5083, Smoking N = 4760. For socio-economic classification Missing are included in the Not classified category, which also contains people who never worked or were long-term unemployed and therefore could not be assigned a classification based on occupation.</p>", "links"=>[], "tags"=>["researcher", "recruitment", "UK COSMOS cohort study", "21 st century", "participant", "research", "method", "data collection", "benefit", "Cohort studies"], "article_id"=>1474649, "categories"=>["Science Policy"], "users"=>["Mireille B. Toledano", "Rachel B. Smith", "James P. Brook", "Margaret Douglass", "Paul Elliott"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0131521.g002", "stats"=>{"downloads"=>2, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_participants_from_two_major_recruitment_campaigns_to_the_UK_COSMOS_study_Phases_2_and_7_/1474649", "title"=>"Characteristics of participants from two major recruitment campaigns to the UK COSMOS study (Phases 2 and 7).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-07-06 04:02:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/2163794"], "description"=>"<p>Footnotes:</p><p><sup>a</sup> Total includes N = 53 additional volunteers who were recruited between Phase 3 and 5 (and chronologically collectively classed as Phase 4), in response to various recruitment strategies, including 2 participants recruited via a Facebook advert trial; these strategies were run concurrently and response rates cannot be calculated for comparisons, therefore are not shown in detail here.</p><p><sup>b</sup> Gift voucher offer in Phase 6 ceased at Day 25 (17/06/2012).</p><p><sup>c</sup> Gift voucher offer in Phase 7 ceased at Day 20 (05/09/2012), as recruitment target of 100,000 reached.</p><p><sup>d</sup> Number of invitations actually received, opened and read may be lower, e.g. if invitation is returned to Sender</p><p>Summary of Study Methods and Participation By Recruitment Phase of the UK COSMOS Study, 2009–2012.</p>", "links"=>[], "tags"=>["researcher", "recruitment", "UK COSMOS cohort study", "21 st century", "participant", "research", "method", "data collection", "benefit", "Cohort studies"], "article_id"=>1474651, "categories"=>["Science Policy"], "users"=>["Mireille B. Toledano", "Rachel B. Smith", "James P. Brook", "Margaret Douglass", "Paul Elliott"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0131521.t001", "stats"=>{"downloads"=>7, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Summary_of_Study_Methods_and_Participation_By_Recruitment_Phase_of_the_UK_COSMOS_Study_2009_8211_2012_/1474651", "title"=>"Summary of Study Methods and Participation By Recruitment Phase of the UK COSMOS Study, 2009–2012.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-07-06 04:02:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/2163788"], "description"=>"<p>Fig 1 Footnotes: Phase 1 used a mobile phone subscriber sampling frame, letter invitation, paper consent and registration, questionnaire via paper or web and no incentive. Phase 2 used a mobile phone subscriber sampling frame, letter invitation, web-based consent, registration, and questionnaire and a prize draw incentive. Phase 3 used a direct marketing list sampling frame, SMS invitation, web-based consent, registration, and questionnaire and no incentive. Phase 5 used an electoral register sampling frame, letter invitation, web-based consent, registration, and questionnaire and a prize draw incentive. Phase 6 used an electoral register sampling frame, letter invitation, web-based consent, registration, and questionnaire and a gift voucher incentive. Phase 7 used an electoral register sampling frame, letter invitation, web-based consent, registration, and questionnaire and a gift voucher incentive. ‘Invitation only’ represents recruitment of invitee named on letter, and ‘Spin-off recruitment’ represents recruitment of additional friends and family.</p>", "links"=>[], "tags"=>["researcher", "recruitment", "UK COSMOS cohort study", "21 st century", "participant", "research", "method", "data collection", "benefit", "Cohort studies"], "article_id"=>1474645, "categories"=>["Science Policy"], "users"=>["Mireille B. Toledano", "Rachel B. Smith", "James P. Brook", "Margaret Douglass", "Paul Elliott"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0131521.g001", "stats"=>{"downloads"=>1, "page_views"=>21, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Cumulative_response_rates_to_UK_COSMOS_study_invitations_by_recruitment_phase_2009_8211_2012_/1474645", "title"=>"Cumulative response rates to UK COSMOS study invitations, by recruitment phase, 2009–2012.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-07-06 04:02:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/2163796"], "description"=>"<div><p>Large-scale prospective cohort studies are invaluable in epidemiology, but they are increasingly difficult and costly to establish and follow-up. More efficient methods for recruitment, data collection and follow-up are essential if such studies are to remain feasible with limited public and research funds. Here, we discuss how these challenges were addressed in the UK COSMOS cohort study where fixed budget and limited time frame necessitated new approaches to consent and recruitment between 2009-2012. Web-based e-consent and data collection should be considered in large scale observational studies, as they offer a streamlined experience which benefits both participants and researchers and save costs. Commercial providers of register and marketing data, smartphones, apps, email, social media, and the internet offer innovative possibilities for identifying, recruiting and following up cohorts. Using examples from UK COSMOS, this article sets out the dos and don’ts for today's cohort studies and provides a guide on how best to take advantage of new technologies and innovative methods to simplify logistics and minimise costs. Thus a more streamlined experience to the benefit of both research participants and researchers becomes achievable.</p></div>", "links"=>[], "tags"=>["researcher", "recruitment", "UK COSMOS cohort study", "21 st century", "participant", "research", "method", "data collection", "benefit", "Cohort studies"], "article_id"=>1474653, "categories"=>["Science Policy"], "users"=>["Mireille B. Toledano", "Rachel B. Smith", "James P. Brook", "Margaret Douglass", "Paul Elliott"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0131521", "stats"=>{"downloads"=>0, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_How_to_Establish_and_Follow_up_a_Large_Prospective_Cohort_Study_in_the_21st_Century_Lessons_from_UK_COSMOS_/1474653", "title"=>"How to Establish and Follow up a Large Prospective Cohort Study in the 21st Century - Lessons from UK COSMOS", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-07-06 04:02:16"}

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Relative Metric

{"start_date"=>"2015-01-01T00:00:00Z", "end_date"=>"2015-12-31T00:00:00Z", "subject_areas"=>[]}
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