No Evidence that Infection Alters Global Recombination Rate in House Mice
Publication Date
November 09, 2015
Journal
PLOS ONE
Authors
Beth L. Dumont, Amy A. Devlin, Dana M. Truempy, Jennifer C. Miller, et al
Volume
10
Issue
11
Pages
e0142266
DOI
https://dx.plos.org/10.1371/journal.pone.0142266
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0142266
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/26550833
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638334
Europe PMC
http://europepmc.org/abstract/MED/26550833
Scopus
84952705634
Mendeley
http://www.mendeley.com/research/evidence-infection-alters-global-recombination-rate-house-mice
Events
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Mendeley | Further Information

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Scopus | Further Information

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Figshare

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  • {"files"=>["https://ndownloader.figshare.com/files/2433596"], "description"=>"<p>Mock MLH1 datasets for infected and uninfected animals were simulated using parameter values derived from observed MLH1 data under the assumption that focus counts are normally distributed. Power was computed as the fraction of 1000 simulated datasets with a non-parametric Mann-Whitney U-test P-value <0.05.</p>", "links"=>[], "tags"=>["MLH 1 mapping", "alternative house mouse pathogens", "Infection Alters Global Recombination Rate", "bacterium Borrelia burgdorferi", "infection", "recombination rate response", "Crossover rates", "recombination rate differences", "House Mice Recombination rate"], "article_id"=>1597845, "categories"=>["Uncategorised"], "users"=>["Beth L. Dumont", "Amy A. Devlin", "Dana M. Truempy", "Jennifer C. Miller", "Nadia D. Singh"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0142266.g002", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Power_to_find_differences_in_mean_MLH1_focus_count_by_the_Mann_Whitney_U_Test_/1597845", "title"=>"Power to find differences in mean MLH1 focus count by the Mann-Whitney U-Test.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-11-09 02:54:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/2433595"], "description"=>"<p>SCP3, a component of the lateral elements of the synaptonemal complex, is stained in red. Sites of crossing over along the synaptonemal complex are denoted by green MLH1 foci. Centromeric proteins targeted by CREST antibodies are in blue. The white arrow points to the heterogametic sex chromosomes. Only MLH1 foci on autosomal bivalents were scored in this study (n = 23 for this image).</p>", "links"=>[], "tags"=>["MLH 1 mapping", "alternative house mouse pathogens", "Infection Alters Global Recombination Rate", "bacterium Borrelia burgdorferi", "infection", "recombination rate response", "Crossover rates", "recombination rate differences", "House Mice Recombination rate"], "article_id"=>1597844, "categories"=>["Uncategorised"], "users"=>["Beth L. Dumont", "Amy A. Devlin", "Dana M. Truempy", "Jennifer C. Miller", "Nadia D. Singh"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0142266.g001", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Representative_image_of_a_late_pachytene_spermatocyte_stained_with_fluorescently_labeled_antibodies_/1597844", "title"=>"Representative image of a late pachytene spermatocyte stained with fluorescently labeled antibodies.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2015-11-09 02:54:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/2433601"], "description"=>"<p>Variation in meiotic and recombination sub-phenotypes across treatment groups.</p>", "links"=>[], "tags"=>["MLH 1 mapping", "alternative house mouse pathogens", "Infection Alters Global Recombination Rate", "bacterium Borrelia burgdorferi", "infection", "recombination rate response", "Crossover rates", "recombination rate differences", "House Mice Recombination rate"], "article_id"=>1597849, "categories"=>["Uncategorised"], "users"=>["Beth L. Dumont", "Amy A. Devlin", "Dana M. Truempy", "Jennifer C. Miller", "Nadia D. Singh"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0142266.t003", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Variation_in_meiotic_and_recombination_sub_phenotypes_across_treatment_groups_/1597849", "title"=>"Variation in meiotic and recombination sub-phenotypes across treatment groups.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-11-09 02:54:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/2433598"], "description"=>"<p><i>P</i>-values from Mann-Whitney U-Tests comparing MLH1 foci counts in infected and control animals.</p>", "links"=>[], "tags"=>["MLH 1 mapping", "alternative house mouse pathogens", "Infection Alters Global Recombination Rate", "bacterium Borrelia burgdorferi", "infection", "recombination rate response", "Crossover rates", "recombination rate differences", "House Mice Recombination rate"], "article_id"=>1597847, "categories"=>["Uncategorised"], "users"=>["Beth L. Dumont", "Amy A. Devlin", "Dana M. Truempy", "Jennifer C. Miller", "Nadia D. Singh"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0142266.t002", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_P_values_from_Mann_Whitney_U_Tests_comparing_MLH1_foci_counts_in_infected_and_control_animals_/1597847", "title"=>"<i>P</i>-values from Mann-Whitney U-Tests comparing MLH1 foci counts in infected and control animals.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2015-11-09 02:54:34"}
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Relative Metric

{"start_date"=>"2015-01-01T00:00:00Z", "end_date"=>"2015-12-31T00:00:00Z", "subject_areas"=>[]}
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