Projected Impact of Salt Restriction on Prevention of Cardiovascular Disease in China: A Modeling Study
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{"title"=>"Projected impact of salt restriction on prevention of cardiovascular disease in China: A modeling study", "type"=>"journal", "authors"=>[{"first_name"=>"Miao", "last_name"=>"Wang", "scopus_author_id"=>"55551933100"}, {"first_name"=>"Andrew E.", "last_name"=>"Moran", "scopus_author_id"=>"7201919170"}, {"first_name"=>"Jing", "last_name"=>"Liu", "scopus_author_id"=>"55993602300"}, {"first_name"=>"Pamela G.", "last_name"=>"Coxson", "scopus_author_id"=>"6701533847"}, {"first_name"=>"Joanne", "last_name"=>"Penko", "scopus_author_id"=>"6508274163"}, {"first_name"=>"Lee", "last_name"=>"Goldman", "scopus_author_id"=>"55584794058"}, {"first_name"=>"Kirsten", "last_name"=>"Bibbins-Domingo", "scopus_author_id"=>"6602998101"}, {"first_name"=>"Dong", "last_name"=>"Zhao", "scopus_author_id"=>"7403490100"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84959010675", "pui"=>"608396086", "doi"=>"10.1371/journal.pone.0146820", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "sgr"=>"84959010675", "pmid"=>"26840409"}, "id"=>"8a809fa0-4fc3-3ac9-a46f-f39e4325c0d5", "abstract"=>"OBJECTIVES: To estimate the effects of achieving China's national goals for dietary salt (NaCl) reduction or implementing culturally-tailored dietary salt restriction strategies on cardiovascular disease (CVD) prevention., METHODS: The CVD Policy Model was used to project blood pressure lowering and subsequent downstream prevented CVD that could be achieved by population-wide salt restriction in China. Outcomes were annual CVD events prevented, relative reductions in rates of CVD incidence and mortality, quality-adjusted life-years (QALYs) gained, and CVD treatment costs saved., RESULTS: Reducing mean dietary salt intake to 9.0 g/day gradually over 10 years could prevent approximately 197 000 incident annual CVD events [95% uncertainty interval (UI): 173 000-219 000], reduce annual CVD mortality by approximately 2.5% (2.2-2.8%), gain 303 000 annual QALYs (278 000-329 000), and save approximately 1.4 billion international dollars (Int$) in annual CVD costs (Int$; 1.2-1.6 billion). Reducing mean salt intake to 6.0 g/day could approximately double these benefits. Implementing cooking salt-restriction spoons could prevent 183 000 fewer incident CVD cases (153 000-215 000) and avoid Int$1.4 billion in CVD treatment costs annually (1.2-1.7 billion). Implementing a cooking salt substitute strategy could lead to approximately three times the health benefits of the salt-restriction spoon program. More than three-quarters of benefits from any dietary salt reduction strategy would be realized in hypertensive adults., CONCLUSION: China could derive substantial health gains from implementation of population-wide dietary salt reduction policies. Most health benefits from any dietary salt reduction program would be realized in adults with hypertension.", "link"=>"http://www.mendeley.com/research/projected-impact-salt-restriction-prevention-cardiovascular-disease-china-modeling-study", "reader_count"=>18, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>1, "Student > Master"=>5, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>1, "Student > Master"=>5, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>4, "Nursing and Health Professions"=>2, "Medicine and Dentistry"=>9, "Agricultural and Biological Sciences"=>1, "Social Sciences"=>1, "Economics, Econometrics and Finance"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>9}, "Social Sciences"=>{"Social Sciences"=>1}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Unspecified"=>{"Unspecified"=>4}}, "reader_count_by_country"=>{"United States"=>1}, "group_count"=>1}

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Figshare

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  • {"files"=>["https://ndownloader.figshare.com/files/4254268"], "description"=>"<p>Simulated SBP reduction and annual cardiovascular disease outcomes (coronary heart disease and stroke combined) after implementing dietary salt intervention strategies in China, 2010 to 2019, according to the CVD Policy Model-China.</p>", "links"=>[], "tags"=>["project blood pressure", "cooking salt substitute strategy", "salt reduction program", "QALY", "CVD treatment costs saved.ResultsReducing", "salt reduction strategy", "UI", "Modeling Study ObjectivesTo estimate", "salt intake", "health benefits", "prevention.MethodsThe CVD Policy Model", "salt reduction policies", "197 000 incident", "salt restriction strategies", "CVD treatment costs"], "article_id"=>2605015, "categories"=>["Medicine", "Biotechnology", "Cancer", "Infectious Diseases"], "users"=>["Miao Wang", "Andrew E. Moran", "Jing Liu", "Pamela G. Coxson", "Joanne Penko", "Lee Goldman", "Kirsten Bibbins-Domingo", "Dong Zhao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0146820.t004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Simulated_SBP_reduction_and_annual_cardiovascular_disease_outcomes_coronary_heart_disease_and_stroke_combined_after_implementing_dietary_salt_intervention_strategies_in_China_2010_to_2019_according_to_the_CVD_Policy_Model_China_/2605015", "title"=>"Simulated SBP reduction and annual cardiovascular disease outcomes (coronary heart disease and stroke combined) after implementing dietary salt intervention strategies in China, 2010 to 2019, according to the CVD Policy Model-China.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-03 22:14:20"}
  • {"files"=>["https://ndownloader.figshare.com/files/4254241"], "description"=>"<p>Mean SBP levels, salt intake level, and relative risks of CVD associated with SBP changes within CVD Policy Model categories.</p>", "links"=>[], "tags"=>["project blood pressure", "cooking salt substitute strategy", "salt reduction program", "QALY", "CVD treatment costs saved.ResultsReducing", "salt reduction strategy", "UI", "Modeling Study ObjectivesTo estimate", "salt intake", "health benefits", "prevention.MethodsThe CVD Policy Model", "salt reduction policies", "197 000 incident", "salt restriction strategies", "CVD treatment costs"], "article_id"=>2604988, "categories"=>["Medicine", "Biotechnology", "Cancer", "Infectious Diseases"], "users"=>["Miao Wang", "Andrew E. Moran", "Jing Liu", "Pamela G. Coxson", "Joanne Penko", "Lee Goldman", "Kirsten Bibbins-Domingo", "Dong Zhao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0146820.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Mean_SBP_levels_salt_intake_level_and_relative_risks_of_CVD_associated_with_SBP_changes_within_CVD_Policy_Model_categories_/2604988", "title"=>"Mean SBP levels, salt intake level, and relative risks of CVD associated with SBP changes within CVD Policy Model categories.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-03 22:14:20"}
  • {"files"=>["https://ndownloader.figshare.com/files/4254172", "https://ndownloader.figshare.com/files/4254175", "https://ndownloader.figshare.com/files/4254181"], "description"=>"<div><p>Objectives</p><p>To estimate the effects of achieving China’s national goals for dietary salt (NaCl) reduction or implementing culturally-tailored dietary salt restriction strategies on cardiovascular disease (CVD) prevention.</p><p>Methods</p><p>The CVD Policy Model was used to project blood pressure lowering and subsequent downstream prevented CVD that could be achieved by population-wide salt restriction in China. Outcomes were annual CVD events prevented, relative reductions in rates of CVD incidence and mortality, quality-adjusted life-years (QALYs) gained, and CVD treatment costs saved.</p><p>Results</p><p>Reducing mean dietary salt intake to 9.0 g/day gradually over 10 years could prevent approximately 197 000 incident annual CVD events [95% uncertainty interval (UI): 173 000–219 000], reduce annual CVD mortality by approximately 2.5% (2.2–2.8%), gain 303 000 annual QALYs (278 000–329 000), and save approximately 1.4 billion international dollars (Int$) in annual CVD costs (Int$; 1.2–1.6 billion). Reducing mean salt intake to 6.0 g/day could approximately double these benefits. Implementing cooking salt-restriction spoons could prevent 183 000 fewer incident CVD cases (153 000–215 000) and avoid Int$1.4 billion in CVD treatment costs annually (1.2–1.7 billion). Implementing a cooking salt substitute strategy could lead to approximately three times the health benefits of the salt-restriction spoon program. More than three-quarters of benefits from any dietary salt reduction strategy would be realized in hypertensive adults.</p><p>Conclusion</p><p>China could derive substantial health gains from implementation of population-wide dietary salt reduction policies. Most health benefits from any dietary salt reduction program would be realized in adults with hypertension.</p></div>", "links"=>[], "tags"=>["project blood pressure", "cooking salt substitute strategy", "salt reduction program", "QALY", "CVD treatment costs saved.ResultsReducing", "salt reduction strategy", "UI", "Modeling Study ObjectivesTo estimate", "salt intake", "health benefits", "prevention.MethodsThe CVD Policy Model", "salt reduction policies", "197 000 incident", "salt restriction strategies", "CVD treatment costs"], "article_id"=>2604925, "categories"=>["Medicine", "Biotechnology", "Cancer", "Infectious Diseases"], "users"=>["Miao Wang", "Andrew E. Moran", "Jing Liu", "Pamela G. Coxson", "Joanne Penko", "Lee Goldman", "Kirsten Bibbins-Domingo", "Dong Zhao"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0146820.s001", "https://dx.doi.org/10.1371/journal.pone.0146820.s002", "https://dx.doi.org/10.1371/journal.pone.0146820.s003"], "stats"=>{"downloads"=>1, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Projected_Impact_of_Salt_Restriction_on_Prevention_of_Cardiovascular_Disease_in_China_A_Modeling_Study/2604925", "title"=>"Projected Impact of Salt Restriction on Prevention of Cardiovascular Disease in China: A Modeling Study", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2016-02-03 22:14:20"}

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{"start_date"=>"2016-01-01T00:00:00Z", "end_date"=>"2016-12-31T00:00:00Z", "subject_areas"=>[]}
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