Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity
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{"title"=>"Reducing short-wavelength blue light in dry eye patients with unstable tear film improves performance on tests of visual acuity", "type"=>"journal", "authors"=>[{"first_name"=>"Minako", "last_name"=>"Kaido", "scopus_author_id"=>"8322884800"}, {"first_name"=>"Ikuko", "last_name"=>"Toda", "scopus_author_id"=>"7007184842"}, {"first_name"=>"Tomoo", "last_name"=>"Oobayashi", "scopus_author_id"=>"57188769347"}, {"first_name"=>"Motoko", "last_name"=>"Kawashima", "scopus_author_id"=>"7201354818"}, {"first_name"=>"Yusaku", "last_name"=>"Katada", "scopus_author_id"=>"57188714944"}, {"first_name"=>"Kazuo", "last_name"=>"Tsubota", "scopus_author_id"=>"36044308900"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"27045760", "doi"=>"10.1371/journal.pone.0152936", "sgr"=>"84962787579", "scopus"=>"2-s2.0-84962787579", "issn"=>"19326203", "pui"=>"609632572"}, "id"=>"8125d887-1c49-3518-961e-187336ef550c", "abstract"=>"PURPOSE: To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE).\\n\\nMETHODS: Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23-43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20-49 years) underwent functional visual acuity (VA) examinations with and without wearing eyeglasses with 50% blue light blocked lenses. The functional VA parameters were starting VA, functional VA, and visual maintenance ratio.\\n\\nRESULTS: The baseline mean values (logarithm of the minimum angle of resolution, logMAR) of functional VA and the visual maintenance ratio were significantly worse in the DE patients than in the controls (P < 0.05), while no significant difference was observed in the baseline starting VA (P > 0.05). The DE patients had significant improvement in mean functional VA and visual maintenance ratio while wearing the glasses (P < 0.05), while there were no significant changes with and without the glasses in the control group (P > 0.05).\\n\\nCONCLUSIONS: Protecting the eyes from short-wavelength blue light may help to ameliorate visual impairment associated with tear instability in patients with DE. This finding represents a new concept, which is that the blue light exposure might be harmful to visual function in patients with short BUT DE.", "link"=>"http://www.mendeley.com/research/reducing-shortwavelength-blue-light-dry-eye-patients-unstable-tear-film-improves-performance-tests-v", "reader_count"=>14, "reader_count_by_academic_status"=>{"Student > Doctoral Student"=>2, "Researcher"=>1, "Student > Ph. D. Student"=>7, "Other"=>1, "Student > Bachelor"=>2, "Lecturer"=>1}, "reader_count_by_user_role"=>{"Student > Doctoral Student"=>2, "Researcher"=>1, "Student > Ph. D. Student"=>7, "Other"=>1, "Student > Bachelor"=>2, "Lecturer"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>1, "Environmental Science"=>1, "Nursing and Health Professions"=>2, "Materials Science"=>1, "Medicine and Dentistry"=>8, "Neuroscience"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>8}, "Neuroscience"=>{"Neuroscience"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Environmental Science"=>{"Environmental Science"=>1}}, "group_count"=>1}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/4919782"], "description"=>"<p>a. The red light passes through the skim milk in a glass. b. The blue light scatters and little of it passes through the skim milk in a glass.</p>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158386, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936.g003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Rayleigh_scattering_phenomenon_/3158386", "title"=>"Rayleigh scattering phenomenon.", "pos_in_sequence"=>4, "defined_type"=>1, "published_date"=>"2016-04-05 08:36:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/4919698"], "description"=>"<p>a: Spectacles with 50% blue light blocked lenses. b: Spectral transmittance curve.</p>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158308, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936.g001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Spectacles_with_50_blue_light_blocked_lenses_and_spectral_transmittance_curve_/3158308", "title"=>"Spectacles with 50% blue light blocked lenses and spectral transmittance curve.", "pos_in_sequence"=>2, "defined_type"=>1, "published_date"=>"2016-04-05 08:36:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/4919824"], "description"=>"<p>Red and blue lines represent red and blue light, respectively. a. Unstable tear film without blue light blocked lens. The blue light is scattering. b. Unstable tear film with blue light blocked lens. The lens is blocking the blue light.</p>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158422, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936.g004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Mechanism_of_the_effect_of_the_blue_light_blocked_lens_on_visual_function_/3158422", "title"=>"Mechanism of the effect of the blue light blocked lens on visual function.", "pos_in_sequence"=>5, "defined_type"=>1, "published_date"=>"2016-04-05 08:36:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/4919644"], "description"=>"<div><p>Purpose</p><p>To investigate whether suppression of blue light can improve visual function in patients with short tear break up time (BUT) dry eye (DE).</p><p>Methods</p><p>Twenty-two patients with short BUT DE (10 men, 12 women; mean age, 32.4 ± 6.4 years; age range, 23–43 years) and 18 healthy controls (10 men, 8 women; mean age, 30.1 ± 7.4 years; age range, 20–49 years) underwent functional visual acuity (VA) examinations with and without wearing eyeglasses with 50% blue light blocked lenses. The functional VA parameters were starting VA, functional VA, and visual maintenance ratio.</p><p>Results</p><p>The baseline mean values (logarithm of the minimum angle of resolution, logMAR) of functional VA and the visual maintenance ratio were significantly worse in the DE patients than in the controls (<i>P</i> < 0.05), while no significant difference was observed in the baseline starting VA (<i>P</i> > 0.05). The DE patients had significant improvement in mean functional VA and visual maintenance ratio while wearing the glasses (<i>P</i> < 0.05), while there were no significant changes with and without the glasses in the control group (<i>P</i> > 0.05),</p><p>Conclusions</p><p>Protecting the eyes from short-wavelength blue light may help to ameliorate visual impairment associated with tear instability in patients with DE. This finding represents a new concept, which is that the blue light exposure might be harmful to visual function in patients with short BUT DE.</p></div>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158260, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936", "stats"=>{"downloads"=>1, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Reducing_Short_Wavelength_Blue_Light_in_Dry_Eye_Patients_with_Unstable_Tear_Film_Improves_Performance_on_Tests_of_Visual_Acuity/3158260", "title"=>"Reducing Short-Wavelength Blue Light in Dry Eye Patients with Unstable Tear Film Improves Performance on Tests of Visual Acuity", "pos_in_sequence"=>1, "defined_type"=>3, "published_date"=>"2016-04-05 08:36:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/4919857"], "description"=>"<p>Characteristics.</p>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158458, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Characteristics_/3158458", "title"=>"Characteristics.", "pos_in_sequence"=>6, "defined_type"=>3, "published_date"=>"2016-04-05 08:36:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/4919743"], "description"=>"<p>Functional visual acuity (VA) parameters with and without blue light blocked glasses.</p>", "links"=>[], "tags"=>["maintenance ratio", "Visual Acuity Purpose", "BUT", "Unstable Tear Film", "DE patients", "VA", "Dry Eye Patients", "age range"], "article_id"=>3158350, "categories"=>["Biochemistry", "Medicine", "Cell Biology", "Neuroscience", "Physiology", "Biotechnology", "Mathematical Sciences not elsewhere classified", "Developmental Biology", "Cancer", "Mental Health", "Infectious Diseases"], "users"=>["Minako Kaido", "Ikuko Toda", "Tomoo Oobayashi", "Motoko Kawashima", "Yusaku Katada", "Kazuo Tsubota"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0152936.g002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Functional_visual_acuity_VA_parameters_with_and_without_blue_light_blocked_glasses_/3158350", "title"=>"Functional visual acuity (VA) parameters with and without blue light blocked glasses.", "pos_in_sequence"=>3, "defined_type"=>1, "published_date"=>"2016-04-05 08:36:22"}

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{"start_date"=>"2016-01-01T00:00:00Z", "end_date"=>"2016-12-31T00:00:00Z", "subject_areas"=>[]}
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