Risk of Cataract Incidence in a Cohort of Mayak PA Workers following Chronic Occupational Radiation Exposure
Publication Date
October 10, 2016
Journal
PLOS ONE
Authors
Tamara V. Azizova, Evgeny V. Bragin, Nobuyuki Hamada & Maria V. Bannikova
Volume
11
Issue
10
Pages
e0164357
DOI
https://dx.plos.org/10.1371/journal.pone.0164357
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0164357
Scopus
84991475866
Mendeley
http://www.mendeley.com/research/risk-cataract-incidence-cohort-mayak-pa-workers-following-chronic-occupational-radiation-exposure
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Mendeley | Further Information

{"title"=>"Risk of cataract incidence in a cohort of mayak pa workers following chronic occupational radiation exposure", "type"=>"journal", "authors"=>[{"first_name"=>"Tamara V.", "last_name"=>"Azizova", "scopus_author_id"=>"6602863813"}, {"first_name"=>"Evgeny V.", "last_name"=>"Bragin", "scopus_author_id"=>"55992077700"}, {"first_name"=>"Nobuyuki", "last_name"=>"Hamada", "scopus_author_id"=>"7201478986"}, {"first_name"=>"Maria V.", "last_name"=>"Bannikova", "scopus_author_id"=>"55991218100"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "pmid"=>"27723789", "scopus"=>"2-s2.0-84991475866", "pui"=>"612655911", "doi"=>"10.1371/journal.pone.0164357", "sgr"=>"84991475866"}, "id"=>"39a8a0f7-5c8c-3b66-bd2a-1faeb54929b1", "abstract"=>"This is the first study of cataract incidence in a cohort of Mayak Production Association workers first employed at one of the main facilities in 1948–1982 and followed up till the end of 2008 (22,377 workers). Principal advantages of the study are the large size of the cohort, long?term follow?up and sufficient statistical power, available results of annual eye examinations over the entire follow?up period and detailed information on non?radiation confounders. Individual measured doses from external γ?rays and neutrons used in the analyses were provided by the Mayak Worker Dosimetry System 2008 (MWDS?2008). Relative risk (RR) and excess relative risk (ERR) per unit dose (Gy) were calculated based on maximum likelihood using the AMFIT module of the EPICURE software. The RR of cataract incidence was found to be the highest in workers exposed at doses above 2.0 Gy. A significant linear association of cataract incidence with cumulative dose from external γ?rays was found with ERR/Gy equal to 0.28 (95% confidence intervals: 0.20, 0.37). The results obtained varied slightly with inclusion of additional adjustments for non?radiation factors (smoking index, hypertension, glaucoma and body mass index). Adjusting for the dose from neutrons gave a considerable increase in ERR/Gy for cataract incidence.", "link"=>"http://www.mendeley.com/research/risk-cataract-incidence-cohort-mayak-pa-workers-following-chronic-occupational-radiation-exposure", "reader_count"=>8, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Researcher"=>2, "Student > Ph. D. Student"=>1, "Student > Master"=>2, "Student > Bachelor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Researcher"=>2, "Student > Ph. D. Student"=>1, "Student > Master"=>2, "Student > Bachelor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Biochemistry, Genetics and Molecular Biology"=>1, "Nursing and Health Professions"=>1, "Medicine and Dentistry"=>3, "Physics and Astronomy"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Physics and Astronomy"=>{"Physics and Astronomy"=>2}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>1}

Scopus | Further Information

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