Ratio of C-Reactive Protein to Albumin Predicts Muscle Mass in Adult Patients Undergoing Hemodialysis
Publication Date
October 21, 2016
Journal
PLOS ONE
Authors
Te Chih Wong, Hsiu Yueh Su, Yu Tong Chen, Pei Yu Wu, et al
Volume
11
Issue
10
Pages
e0165403
DOI
https://dx.plos.org/10.1371/journal.pone.0165403
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0165403
Scopus
84992324012
Mendeley
http://www.mendeley.com/research/ratio-creactive-protein-albumin-predicts-muscle-mass-adult-patients-undergoing-hemodialysis
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Mendeley | Further Information

{"title"=>"Ratio of C-reactive protein to albumin predicts muscle mass in adult patients undergoing hemodialysis", "type"=>"journal", "authors"=>[{"first_name"=>"Te Chih", "last_name"=>"Wong", "scopus_author_id"=>"56988344000"}, {"first_name"=>"Hsiu Yueh", "last_name"=>"Su", "scopus_author_id"=>"18736083000"}, {"first_name"=>"Yu Tong", "last_name"=>"Chen", "scopus_author_id"=>"56989042000"}, {"first_name"=>"Pei Yu", "last_name"=>"Wu", "scopus_author_id"=>"56043951000"}, {"first_name"=>"Hsi Hsien", "last_name"=>"Chen", "scopus_author_id"=>"35069121000"}, {"first_name"=>"Tso Hsiao", "last_name"=>"Chen", "scopus_author_id"=>"57154867000"}, {"first_name"=>"Yung Ho", "last_name"=>"Hsu", "scopus_author_id"=>"54913888500"}, {"first_name"=>"Shwu Huey", "last_name"=>"Yang", "scopus_author_id"=>"8676122700"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "sgr"=>"84992324012", "doi"=>"10.1371/journal.pone.0165403", "isbn"=>"1932-6203 (Electronic)\r1932-6203 (Linking)", "pmid"=>"27768746", "scopus"=>"2-s2.0-84992324012", "pui"=>"612862327"}, "id"=>"062b7547-4b3b-33b9-848d-22b18c28be8c", "abstract"=>"Recent studies have indicated that the ratio of C-reactive protein to albumin (CRP-Alb ratio) is associated with clinical outcomes in patients with disease. We examined the predictive value of this ratio in patients undergoing hemodialysis (HD). In this cross-sectional study, 91 eligible adult HD patients were analyzed, and the correlation between the CRP-Alb ratio and skeletal muscle mass normalized for body weight (SMM/wt; estimated using a bioelectrical impedance analyzer) was investigated. The mean age of the study participants was 54.9 ± 6.6 years (ranging from 27 to 64 years); 43 (47.2%) were men. The mean values for the SMM/wt were 39.1% ± 5.4%. The CRP-Alb ratio was found to be negatively correlated with SMM/wt (r = -0.33, P = 0.002) and creatinine (r = -0.20, P = 0.056). All the univariate significant and nonsignificant relevant covariates were selected for multivariable stepwise regression analysis. We determined that the homeostasis model assessment-estimated insulin resistance and CRP-Alb ratio were independent risk determinants for SMM/wt (βHOMA-IR = -0.18 and βCRP-Alb ratio = -3.84, adjusted R2 = 0.32). This study indicated that the CRP-Alb ratio may help clinicians in predicting muscle mass in adult patients undergoing HD.", "link"=>"http://www.mendeley.com/research/ratio-creactive-protein-albumin-predicts-muscle-mass-adult-patients-undergoing-hemodialysis", "reader_count"=>4, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Student > Doctoral Student"=>1, "Student > Bachelor"=>1, "Other"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Student > Doctoral Student"=>1, "Student > Bachelor"=>1, "Other"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Medicine and Dentistry"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>2}, "Unspecified"=>{"Unspecified"=>2}}, "group_count"=>0}

Scopus | Further Information

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