Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil
Publication Date
November 29, 2016
Authors
Itziar Estensoro, Gabriel Ballester Lozano, Laura Benedito Palos, Fabian Grammes, et al
Volume
11
Issue
11
Pages
e0166564
DOI
https://dx.plos.org/10.1371/journal.pone.0166564
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0166564
Scopus
85002374686
Mendeley
http://www.mendeley.com/research/dietary-butyrate-helps-restore-intestinal-status-marine-teleost-sparus-aurata-fed-extreme-diets-low
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Dietary butyrate helps to restore the intestinal status of a marine teleost (Sparus aurata) fed extreme diets low in fish meal and fish oil", "type"=>"journal", "authors"=>[{"first_name"=>"Itziar", "last_name"=>"Estensoro", "scopus_author_id"=>"36542332300"}, {"first_name"=>"Gabriel", "last_name"=>"Ballester-Lozano", "scopus_author_id"=>"36166455300"}, {"first_name"=>"Laura", "last_name"=>"Benedito-Palos", "scopus_author_id"=>"16479918900"}, {"first_name"=>"Fabian", "last_name"=>"Grammes", "scopus_author_id"=>"35310258800"}, {"first_name"=>"Juan Antonio", "last_name"=>"Martos-Sitcha", "scopus_author_id"=>"55217586200"}, {"first_name"=>"Liv Torunn", "last_name"=>"Mydland", "scopus_author_id"=>"12241924600"}, {"first_name"=>"Josep Alvar", "last_name"=>"Calduch-Giner", "scopus_author_id"=>"6602688466"}, {"first_name"=>"Juan", "last_name"=>"Fuentes", "scopus_author_id"=>"7201832526"}, {"first_name"=>"Vasileios", "last_name"=>"Karalazos", "scopus_author_id"=>"8523086700"}, {"first_name"=>"Álvaro", "last_name"=>"Ortiz", "scopus_author_id"=>"57002270300"}, {"first_name"=>"Margareth", "last_name"=>"Øverland", "scopus_author_id"=>"56236554400"}, {"first_name"=>"Ariadna", "last_name"=>"Sitjà-Bobadilla", "scopus_author_id"=>"7003289824"}, {"first_name"=>"Jaume", "last_name"=>"Pérez-Sánchez", "scopus_author_id"=>"7003402196"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "doi"=>"10.1371/journal.pone.0166564", "sgr"=>"85002374686", "scopus"=>"2-s2.0-85002374686", "pmid"=>"27898676", "pui"=>"613480343"}, "id"=>"df878eb8-2258-38ec-b2fe-754f32c52710", "abstract"=>"There is a constant need to find feed additives that improve health and nutrition of farmed fish and lessen the intestinal inflammation induced by plant-based ingredients. The objective of this study was to evaluate the effects of adding an organic acid salt to alleviate some of the detrimental effects of extreme plant-ingredient substitution of fish meal (FM) and fish oil (FO) in gilthead sea bream diet. Three experiments were conducted. In a first trial (T1), the best dose (0.4%) of sodium butyrate (BP-70 ®NOREL) was chosen after a short (9-weeks) feeding period. In a second longer trial (T2) (8 months), four diets were used: a control diet containing 25% FM (T2-D1) and three experimental diets containing 5% FM (T2-D2, T2-D3, T2-D4). FO was the only added oil in D1, while a blend of plant oils replaced 58% and 84% of FO in T2-D2, and T2-D3 and T2-D4, respectively. The latter was supplemented with 0.4% BP-70. In a third trial (T3), two groups of fish were fed for 12 and 38 months with D1, D3 and D4 diets of T2. The effects of dietary changes were studied using histochemical, immunohistochemical, molecular and electrophysiological tools. The extreme diet (T2-D3) modified significantly the transcriptomic profile, especially at the anterior intestine, up-regulating the expression of inflammatory markers, in coincidence with a higher presence of granulocytes and lymphocytes in the submucosa, and changing genes involved in antioxidant defences, epithelial permeability and mucus production. Trans-epithelial electrical resistance (Rt) was also decreased (T3-D3). Most of these modifications were returned to control values with the addition of BP-70. None of the experimental diets modified the staining pattern of PCNA, FABP2 or ALPI. These results further confirm the potential of this additive to improve or reverse the detrimental effects of extreme fish diet formulations.", "link"=>"http://www.mendeley.com/research/dietary-butyrate-helps-restore-intestinal-status-marine-teleost-sparus-aurata-fed-extreme-diets-low", "reader_count"=>25, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>2, "Librarian"=>1, "Student > Doctoral Student"=>2, "Researcher"=>7, "Student > Ph. D. Student"=>4, "Student > Master"=>3, "Student > Bachelor"=>2, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>2, "Librarian"=>1, "Student > Doctoral Student"=>2, "Researcher"=>7, "Student > Ph. D. Student"=>4, "Student > Master"=>3, "Student > Bachelor"=>2, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>4, "Biochemistry, Genetics and Molecular Biology"=>2, "Agricultural and Biological Sciences"=>16, "Arts and Humanities"=>1, "Immunology and Microbiology"=>1, "Economics, Econometrics and Finance"=>1}, "reader_count_by_subdiscipline"=>{"Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>16}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>4}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"Norway"=>1}, "group_count"=>1}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85002374686"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85002374686?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85002374686&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85002374686&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/85002374686", "dc:identifier"=>"SCOPUS_ID:85002374686", "eid"=>"2-s2.0-85002374686", "dc:title"=>"Dietary butyrate helps to restore the intestinal status of a marine teleost (Sparus aurata) fed extreme diets low in fish meal and fish oil", "dc:creator"=>"Estensoro I.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"11", "prism:issueIdentifier"=>"11", "prism:pageRange"=>nil, "prism:coverDate"=>"2016-11-01", "prism:coverDisplayDate"=>"November 2016", "prism:doi"=>"10.1371/journal.pone.0166564", "citedby-count"=>"36", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"CSIC - Instituto de Acuicultura de Torre de la Sal (IATS)", "affiliation-city"=>"Castellon de la Plana", "affiliation-country"=>"Spain"}], "pubmed-id"=>"27898676", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e0166564", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Counter

  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"148", "xml_views"=>"5", "html_views"=>"236"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"60", "xml_views"=>"1", "html_views"=>"117"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"48", "xml_views"=>"1", "html_views"=>"127"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"15", "xml_views"=>"3", "html_views"=>"62"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"56"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"86"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"3", "html_views"=>"80"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"40", "xml_views"=>"5", "html_views"=>"222"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"3", "html_views"=>"49"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"3", "html_views"=>"43"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"18", "xml_views"=>"1", "html_views"=>"151"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"256"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"70"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"34"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"3", "html_views"=>"41"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"30"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"27", "xml_views"=>"3", "html_views"=>"23"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"19"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"17"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"28", "xml_views"=>"0", "html_views"=>"62"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"38"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"33"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"39"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"49", "xml_views"=>"2", "html_views"=>"39"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"54", "xml_views"=>"1", "html_views"=>"34"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"11", "xml_views"=>"3", "html_views"=>"19"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"42", "xml_views"=>"0", "html_views"=>"42"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"6"}

PMC Usage Stats

  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"20", "full-text"=>"25", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"18", "full-text"=>"14", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"16", "full-text"=>"25", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"20", "full-text"=>"18", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"21", "full-text"=>"19", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"20", "full-text"=>"22", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"17", "full-text"=>"19", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"24", "full-text"=>"27", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"19", "full-text"=>"18", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"31", "full-text"=>"37", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"21", "full-text"=>"19", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"14", "full-text"=>"10", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"17", "full-text"=>"18", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"20", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"20", "full-text"=>"22", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"19", "full-text"=>"17", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"41", "full-text"=>"45", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"21", "full-text"=>"17", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"17", "full-text"=>"19", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"23", "full-text"=>"30", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"27", "full-text"=>"27", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"29", "full-text"=>"32", "pdf"=>"15", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"19", "full-text"=>"23", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"27", "full-text"=>"26", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}
Loading … Spinner
There are currently no alerts