Melatonin protects rats from radiotherapy-induced small intestine toxicity
Publication Date
April 12, 2017
Authors
Beatriz Fernández Gil, Ahmed E. Abdel Moneim, Francisco Ortiz, Ying Qiang Shen, et al
Volume
12
Issue
4
Pages
e0174474
DOI
https://dx.plos.org/10.1371/journal.pone.0174474
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0174474
Scopus
85017651596
Mendeley
http://www.mendeley.com/research/melatonin-protects-rats-radiotherapyinduced-small-intestine-toxicity
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Melatonin protects rats from radiotherapyinduced small intestine toxicity", "type"=>"journal", "authors"=>[{"first_name"=>"Beatriz", "last_name"=>"Fernandez-Gil", "scopus_author_id"=>"57073880700"}, {"first_name"=>"Ahmed E.", "last_name"=>"Abdel Moneim", "scopus_author_id"=>"36551920900"}, {"first_name"=>"Francisco", "last_name"=>"Ortiz", "scopus_author_id"=>"15758165800"}, {"first_name"=>"Ying Qiang", "last_name"=>"Shen", "scopus_author_id"=>"57193955159"}, {"first_name"=>"Viviana", "last_name"=>"Soto-Mercado", "scopus_author_id"=>"57193948125"}, {"first_name"=>"Miguel", "last_name"=>"Mendivil-Perez", "scopus_author_id"=>"55567740400"}, {"first_name"=>"Ana", "last_name"=>"Guerra-Librero", "scopus_author_id"=>"56928370000"}, {"first_name"=>"Dario", "last_name"=>"Acuña-Castroviejo", "scopus_author_id"=>"35599413200"}, {"first_name"=>"Maria M.", "last_name"=>"Molina-Navarro", "scopus_author_id"=>"57189302674"}, {"first_name"=>"Jose M.", "last_name"=>"Garcia-Verdugo", "scopus_author_id"=>"7004158378"}, {"first_name"=>"Ramy K.A.", "last_name"=>"Sayed", "scopus_author_id"=>"57188992319"}, {"first_name"=>"Javier", "last_name"=>"Florido", "scopus_author_id"=>"57193951128"}, {"first_name"=>"Juan D.", "last_name"=>"Luna", "scopus_author_id"=>"7005926408"}, {"first_name"=>"Luis", "last_name"=>"Carlos Lopez", "scopus_author_id"=>"57193951657"}, {"first_name"=>"Germaine", "last_name"=>"Escames", "scopus_author_id"=>"6701603739"}], "year"=>2017, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"28403142", "doi"=>"10.1371/journal.pone.0174474", "sgr"=>"85017651596", "isbn"=>"1111111111", "scopus"=>"2-s2.0-85017651596", "issn"=>"19326203", "pui"=>"615347382"}, "id"=>"8f91c961-4087-31a6-920f-ded2a6331165", "abstract"=>"Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities fol- lowing radiotherapy. Prevention of radiation enteropathy requires protection of the small intestine. However, despite the prevalence and burden of this pathology, there are currently no effective treatments for radiotherapy-induced gut toxicity, and this pathology remains unclear. The present study aimed to investigate the changes induced in the rat small intes- tine after external irradiation of the tongue, and to explore the potential radio-protective effects of melatonin gel. Male Wistar rats were subjected to irradiation of their tongues with an X-Ray YXLON Y.Tu 320-D03 irradiator, receiving a dose of 7.5 Gy/day for 5 days. For 21 days post-irradiation, rats were treated with 45 mg/day melatonin gel or vehicle, by local application into their mouths. Our results showed that mitochondrial oxidative stress, bioe- nergetic impairment, and subsequent NLRP3 inflammasome activation were involved in the development of radiotherapy-induced gut toxicity. Oral treatment with melatonin gel had a protective effect in the small intestine, which was associated with mitochondrial protection and, consequently, with a reduced inflammatory response, blunting the NF-κB/NLRP3 inflammasome signaling activation. Thus, rats treated with melatonin gel showed reduced intestinal apoptosis, relieving mucosal dysfunction and facilitating intestinal mucosa recov- ery. Our findings suggest that oral treatment with melatonin gel may be a potential preven- tive therapy for radiotherapy-induced gut toxicity in cancer patients.", "link"=>"http://www.mendeley.com/research/melatonin-protects-rats-radiotherapyinduced-small-intestine-toxicity", "reader_count"=>41, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>3, "Librarian"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>2, "Student > Postgraduate"=>1, "Student > Master"=>9, "Student > Bachelor"=>22, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>3, "Librarian"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>2, "Student > Postgraduate"=>1, "Student > Master"=>9, "Student > Bachelor"=>22, "Professor"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>10, "Unspecified"=>1, "Biochemistry, Genetics and Molecular Biology"=>5, "Materials Science"=>7, "Mathematics"=>1, "Agricultural and Biological Sciences"=>5, "Medicine and Dentistry"=>2, "Physics and Astronomy"=>3, "Chemistry"=>4, "Social Sciences"=>1, "Nursing and Health Professions"=>2}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>10}, "Materials Science"=>{"Materials Science"=>7}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>2}, "Chemistry"=>{"Chemistry"=>4}, "Social Sciences"=>{"Social Sciences"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>5}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>5}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>2}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85017651596"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85017651596?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85017651596&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85017651596&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/85017651596", "dc:identifier"=>"SCOPUS_ID:85017651596", "eid"=>"2-s2.0-85017651596", "dc:title"=>"Melatonin protects rats from radiotherapyinduced small intestine toxicity", "dc:creator"=>"Fernandez-Gil B.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"12", "prism:issueIdentifier"=>"4", "prism:pageRange"=>nil, "prism:coverDate"=>"2017-04-01", "prism:coverDisplayDate"=>"April 2017", "prism:doi"=>"10.1371/journal.pone.0174474", "citedby-count"=>"56", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Universidad de Granada", "affiliation-city"=>"Granada", "affiliation-country"=>"Spain"}], "pubmed-id"=>"28403142", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e0174474", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true, "freetoread"=>{"value"=>[{"$"=>"all"}, {"$"=>"publisherfullgold"}, {"$"=>"repository"}, {"$"=>"repositoryvor"}, {"$"=>"repositoryam"}]}, "freetoreadLabel"=>{"value"=>[{"$"=>"All Open Access"}, {"$"=>"Gold"}, {"$"=>"Green"}]}}

Twitter

Counter

  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"401", "xml_views"=>"26", "html_views"=>"1807"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"178", "xml_views"=>"7", "html_views"=>"1110"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"95"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"73"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"45", "xml_views"=>"2", "html_views"=>"83"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"84"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"81"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"31", "xml_views"=>"1", "html_views"=>"178"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"307"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"45"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"41", "xml_views"=>"2", "html_views"=>"36"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"33"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"9", "xml_views"=>"2", "html_views"=>"36"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"15", "xml_views"=>"3", "html_views"=>"21"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"39"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"47"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"29"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"36"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"33"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"33"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"20", "xml_views"=>"4", "html_views"=>"14"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"19", "xml_views"=>"2", "html_views"=>"11"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"24", "xml_views"=>"2", "html_views"=>"8"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"2"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"11"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"17"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"20"}
  • {"month"=>"9", "year"=>"2020", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"10", "year"=>"2020", "pdf_views"=>"18", "xml_views"=>"2", "html_views"=>"23"}
  • {"month"=>"11", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"3", "html_views"=>"6"}
  • {"month"=>"12", "year"=>"2020", "pdf_views"=>"18", "xml_views"=>"2", "html_views"=>"15"}
  • {"month"=>"1", "year"=>"2021", "pdf_views"=>"12", "xml_views"=>"2", "html_views"=>"14"}
  • {"month"=>"2", "year"=>"2021", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"3", "year"=>"2021", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"4", "year"=>"2021", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"8"}

PMC Usage Stats

  • {"unique-ip"=>"52", "full-text"=>"72", "pdf"=>"27", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"36", "full-text"=>"42", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"39", "full-text"=>"38", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"37", "full-text"=>"36", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"35", "full-text"=>"43", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"30", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"33", "full-text"=>"38", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"36", "full-text"=>"44", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"26", "full-text"=>"21", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"22", "full-text"=>"24", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"18", "full-text"=>"24", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"24", "full-text"=>"21", "pdf"=>"12", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"30", "full-text"=>"35", "pdf"=>"19", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"37", "full-text"=>"43", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"24", "full-text"=>"25", "pdf"=>"21", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"22", "full-text"=>"24", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"16", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"27", "full-text"=>"30", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"30", "full-text"=>"33", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"22", "full-text"=>"24", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"25", "full-text"=>"25", "pdf"=>"12", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"18", "full-text"=>"23", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"12", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"20", "full-text"=>"24", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"30", "full-text"=>"29", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"20", "full-text"=>"25", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"14", "full-text"=>"17", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"21", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"8"}
  • {"unique-ip"=>"19", "full-text"=>"17", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"9"}
  • {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"13", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"11"}
  • {"unique-ip"=>"16", "full-text"=>"19", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2021", "month"=>"1"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2021", "month"=>"2"}
Loading … Spinner
There are currently no alerts