The ghosts of HeLa: How cell line misidentification contaminates the scientific literature
Publication Date
October 12, 2017
Journal
PLOS ONE
Authors
Serge P. J. M. Horbach & Willem Halffman
Volume
12
Issue
10
Pages
e0186281
DOI
https://dx.plos.org/10.1371/journal.pone.0186281
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0186281
Scopus
85031116160
Mendeley
http://www.mendeley.com/research/ghosts-hela-cell-line-misidentification-contaminates-scientific-literature
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Mendeley | Further Information

{"title"=>"The ghosts of HeLa: How cell line misidentification contaminates the scientific literature", "type"=>"journal", "authors"=>[{"first_name"=>"Serge P.J.M.", "last_name"=>"Horbach", "scopus_author_id"=>"57192424820"}, {"first_name"=>"Willem", "last_name"=>"Halffman", "scopus_author_id"=>"12040936000"}], "year"=>2017, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "doi"=>"10.1371/journal.pone.0186281", "sgr"=>"85031116160", "scopus"=>"2-s2.0-85031116160", "isbn"=>"1111111111", "pmid"=>"29023500", "pui"=>"618724091"}, "id"=>"083cfa84-17a8-3654-ac6f-1f6b93426d49", "abstract"=>"While problems with cell line misidentification have been known for decades, an unknown number of published papers remains in circulation reporting on the wrong cells without warning or correction. Here we attempt to make a conservative estimate of this ‘contaminated’ literature. We found 32,755 articles reporting on research with misidentified cells, in turn cited by an estimated half a million other papers. The contamination of the literature is not decreasing over time and is anything but restricted to countries in the periphery of global science. The decades-old and often contentious attempts to stop misidentification of cell lines have proven to be insufficient. The contamination of the literature calls for a fair and reasonable notification system, warning users and readers to interpret these papers with appropriate care.", "link"=>"http://www.mendeley.com/research/ghosts-hela-cell-line-misidentification-contaminates-scientific-literature", "reader_count"=>78, "reader_count_by_academic_status"=>{"Unspecified"=>4, "Professor > Associate Professor"=>3, "Librarian"=>2, "Researcher"=>19, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>1, "Student > Master"=>12, "Other"=>4, "Student > Bachelor"=>9, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>4, "Professor > Associate Professor"=>3, "Librarian"=>2, "Researcher"=>19, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>1, "Student > Master"=>12, "Other"=>4, "Student > Bachelor"=>9, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Agricultural and Biological Sciences"=>21, "Arts and Humanities"=>1, "Chemistry"=>4, "Computer Science"=>3, "Engineering"=>4, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>14, "Mathematics"=>1, "Medicine and Dentistry"=>6, "Pharmacology, Toxicology and Pharmaceutical Science"=>8, "Physics and Astronomy"=>2, "Psychology"=>1, "Immunology and Microbiology"=>5, "Neuroscience"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>6}, "Physics and Astronomy"=>{"Physics and Astronomy"=>2}, "Psychology"=>{"Psychology"=>1}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>5}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>8}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Engineering"=>{"Engineering"=>4}, "Chemistry"=>{"Chemistry"=>4}, "Neuroscience"=>{"Neuroscience"=>2}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>5}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>21}, "Computer Science"=>{"Computer Science"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>14}}, "group_count"=>5}

Scopus | Further Information

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