Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population", "type"=>"journal", "authors"=>[{"first_name"=>"Nelly", "last_name"=>"Scuda", "scopus_author_id"=>"36609078600"}, {"first_name"=>"Nadege Freda", "last_name"=>"Madinda", "scopus_author_id"=>"56049931500"}, {"first_name"=>"Chantal", "last_name"=>"Akoua-Koffi", "scopus_author_id"=>"55908558300"}, {"first_name"=>"Edgard Valerie", "last_name"=>"Adjogoua", "scopus_author_id"=>"16644563000"}, {"first_name"=>"Diana", "last_name"=>"Wevers", "scopus_author_id"=>"36609262600"}, {"first_name"=>"Jörg", "last_name"=>"Hofmann", "scopus_author_id"=>"7103042984"}, {"first_name"=>"Kenneth N.", "last_name"=>"Cameron", "scopus_author_id"=>"7102930644"}, {"first_name"=>"Siv Aina J.", "last_name"=>"Leendertz", "scopus_author_id"=>"36164919500"}, {"first_name"=>"Emmanuel", "last_name"=>"Couacy-Hymann", "scopus_author_id"=>"13003787900"}, {"first_name"=>"Martha", "last_name"=>"Robbins", "scopus_author_id"=>"7202254249"}, {"first_name"=>"Christophe", "last_name"=>"Boesch", "scopus_author_id"=>"26642873000"}, {"first_name"=>"Michael A.", "last_name"=>"Jarvis", "scopus_author_id"=>"7202161123"}, {"first_name"=>"Ugo", "last_name"=>"Moens", "scopus_author_id"=>"7004155038"}, {"first_name"=>"Lawrence", "last_name"=>"Mugisha", "scopus_author_id"=>"35107723300"}, {"first_name"=>"Sébastien", "last_name"=>"Calvignac-Spencer", "scopus_author_id"=>"55139371100"}, {"first_name"=>"Fabian H.", "last_name"=>"Leendertz", "scopus_author_id"=>"6602340558"}, {"first_name"=>"Bernhard", "last_name"=>"Ehlers", "scopus_author_id"=>"7005070616"}], "year"=>2013, "source"=>"PLoS Pathogens", "identifiers"=>{"sgr"=>"84879537028", "issn"=>"15537366", "scopus"=>"2-s2.0-84879537028", "pmid"=>"23818846", "pui"=>"369208257", "isbn"=>"1553-7374 (Electronic)\\r1553-7366 (Linking)", "doi"=>"10.1371/journal.ppat.1003429"}, "id"=>"fa0dd8e9-2e88-32b1-91a0-f6ecfa095767", "abstract"=>"Polyomaviruses are a family of small non-enveloped DNA viruses that encode oncogenes and have been associated, to greater or lesser extent, with human disease and cancer. Currently, twelve polyomaviruses are known to circulate within the human population. To further examine the diversity of human polyomaviruses, we have utilized a combinatorial approach comprised of initial degenerate primer-based PCR identification and phylogenetic analysis of nonhuman primate (NHP) polyomavirus species, followed by polyomavirus-specific serological analysis of human sera. Using this approach we identified twenty novel NHP polyomaviruses: nine in great apes (six in chimpanzees, two in gorillas and one in orangutan), five in Old World monkeys and six in New World monkeys. Phylogenetic analysis indicated that only four of the nine chimpanzee polyomaviruses (six novel and three previously identified) had known close human counterparts. To determine whether the remaining chimpanzee polyomaviruses had potential human counterparts, the major viral capsid proteins (VP1) of four chimpanzee polyomaviruses were expressed in E. coli for use as antigens in enzyme-linked immunoassay (ELISA). Human serum/plasma samples from both Côte d'Ivoire and Germany showed frequent seropositivity for the four viruses. Antibody pre-adsorption-based ELISA excluded the possibility that reactivities resulted from binding to known human polyomaviruses. Together, these results support the existence of additional polyomaviruses circulating within the human population that are genetically and serologically related to existing chimpanzee polyomaviruses.", "link"=>"http://www.mendeley.com/research/novel-polyomaviruses-nonhuman-primates-genetic-serological-predictors-existence-multiple-unknown-pol", "reader_count"=>26, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>2, "Researcher"=>6, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Student > Master"=>2, "Student > Bachelor"=>2, "Professor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>2, "Researcher"=>6, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Student > Master"=>2, "Student > Bachelor"=>2, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Agricultural and Biological Sciences"=>18, "Medicine and Dentistry"=>1, "Veterinary Science and Veterinary Medicine"=>2, "Computer Science"=>1, "Immunology and Microbiology"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>2}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>18}, "Computer Science"=>{"Computer Science"=>1}, "Unspecified"=>{"Unspecified"=>2}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>2}}, "reader_count_by_country"=>{"Czech Republic"=>1, "Netherlands"=>1, "United States"=>2, "Kenya"=>1}, "group_count"=>0}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84879537028"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84879537028?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84879537028&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84879537028&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84879537028", "dc:identifier"=>"SCOPUS_ID:84879537028", "eid"=>"2-s2.0-84879537028", "dc:title"=>"Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population", "dc:creator"=>"Scuda N.", "prism:publicationName"=>"PLoS Pathogens", "prism:issn"=>"15537366", "prism:eIssn"=>"15537374", "prism:volume"=>"9", "prism:issueIdentifier"=>"6", "prism:pageRange"=>nil, "prism:coverDate"=>"2013-06-01", "prism:coverDisplayDate"=>"June 2013", "prism:doi"=>"10.1371/journal.ppat.1003429", "citedby-count"=>"25", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Robert Koch Institut", "affiliation-city"=>"Berlin", "affiliation-country"=>"Germany"}], "pubmed-id"=>"23818846", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1003429", "source-id"=>"4000151809", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplospathogens%2Farticle%3Fid%3D10.1371%252Fjournal.ppat.1003429", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"89", "xml_views"=>"10", "html_views"=>"727"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"62", "xml_views"=>"2", "html_views"=>"306"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"147"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"99"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"118"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"72"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"45"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"63"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"99"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"84"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"109"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"86"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"4", "html_views"=>"84"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"85"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"80"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"61"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"48"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"43"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"81"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"83"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"50"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"40"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"23"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"23"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"19"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"1", "html_views"=>"11"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"11"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"1", "html_views"=>"12"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"16"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"5", "html_views"=>"4"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"5"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"6"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"10"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1095254"], "description"=>"<p>Antibody reactivity was assessed against the 4 chimpanzee polyomaviruses ChPyV, PtrovPyV3, PtrovPyV4 and PtrosPyV2 using plasma of 40 chimpanzees. Samples were analysed for seroreactivity with a capsomer-based IgG ELISA using the VP1 major capsid protein of the above polyomaviruses as antigens. The spread of absorbance measurement is shown with black dots, and cut-off values (COVs) are depicted with solid lines (PtrovPyV3: 0.028; PtrovPyV4: 0.023; PtrosPyV2: 0.013). A COV for ChPyV could not be calculated because all OD<sub>450</sub> values were >0.3.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "chimpanzee", "plasma", "samples", "vp1", "proteins"], "article_id"=>726861, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.g002", "stats"=>{"downloads"=>3, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Reactivity_of_chimpanzee_plasma_samples_to_VP1_proteins_of_chimpanzee_polyomaviruses_/726861", "title"=>"Reactivity of chimpanzee plasma samples to VP1 proteins of chimpanzee polyomaviruses.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-06-20 01:54:21"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095266", "https://ndownloader.figshare.com/files/1095267", "https://ndownloader.figshare.com/files/1095269", "https://ndownloader.figshare.com/files/1095270", "https://ndownloader.figshare.com/files/1095271", "https://ndownloader.figshare.com/files/1095273", "https://ndownloader.figshare.com/files/1095274", "https://ndownloader.figshare.com/files/1095275", "https://ndownloader.figshare.com/files/1095276", "https://ndownloader.figshare.com/files/1095277", "https://ndownloader.figshare.com/files/1095278", "https://ndownloader.figshare.com/files/1095279", "https://ndownloader.figshare.com/files/1095280", "https://ndownloader.figshare.com/files/1095281", "https://ndownloader.figshare.com/files/1095282", "https://ndownloader.figshare.com/files/1095283", "https://ndownloader.figshare.com/files/1095284"], "description"=>"<div><p>Polyomaviruses are a family of small non-enveloped DNA viruses that encode oncogenes and have been associated, to greater or lesser extent, with human disease and cancer. Currently, twelve polyomaviruses are known to circulate within the human population. To further examine the diversity of human polyomaviruses, we have utilized a combinatorial approach comprised of initial degenerate primer-based PCR identification and phylogenetic analysis of nonhuman primate (NHP) polyomavirus species, followed by polyomavirus-specific serological analysis of human sera. Using this approach we identified twenty novel NHP polyomaviruses: nine in great apes (six in chimpanzees, two in gorillas and one in orangutan), five in Old World monkeys and six in New World monkeys. Phylogenetic analysis indicated that only four of the nine chimpanzee polyomaviruses (six novel and three previously identified) had known close human counterparts. To determine whether the remaining chimpanzee polyomaviruses had potential human counterparts, the major viral capsid proteins (VP1) of four chimpanzee polyomaviruses were expressed in <i>E. coli</i> for use as antigens in enzyme-linked immunoassay (ELISA). Human serum/plasma samples from both Côte d'Ivoire and Germany showed frequent seropositivity for the four viruses. Antibody pre-adsorption-based ELISA excluded the possibility that reactivities resulted from binding to known human polyomaviruses. Together, these results support the existence of additional polyomaviruses circulating within the human population that are genetically and serologically related to existing chimpanzee polyomaviruses.</p></div>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "polyomaviruses", "nonhuman", "serological", "predictors"], "article_id"=>726868, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1003429.s001", "https://dx.doi.org/10.1371/journal.ppat.1003429.s002", "https://dx.doi.org/10.1371/journal.ppat.1003429.s003", "https://dx.doi.org/10.1371/journal.ppat.1003429.s004", "https://dx.doi.org/10.1371/journal.ppat.1003429.s005", "https://dx.doi.org/10.1371/journal.ppat.1003429.s006", "https://dx.doi.org/10.1371/journal.ppat.1003429.s007", "https://dx.doi.org/10.1371/journal.ppat.1003429.s008", "https://dx.doi.org/10.1371/journal.ppat.1003429.s009", "https://dx.doi.org/10.1371/journal.ppat.1003429.s010", "https://dx.doi.org/10.1371/journal.ppat.1003429.s011", "https://dx.doi.org/10.1371/journal.ppat.1003429.s012", "https://dx.doi.org/10.1371/journal.ppat.1003429.s013", "https://dx.doi.org/10.1371/journal.ppat.1003429.s014", "https://dx.doi.org/10.1371/journal.ppat.1003429.s015", "https://dx.doi.org/10.1371/journal.ppat.1003429.s016", "https://dx.doi.org/10.1371/journal.ppat.1003429.s017"], "stats"=>{"downloads"=>18, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Novel_Polyomaviruses_of_Nonhuman_Primates_Genetic_and_Serological_Predictors_for_the_Existence_of_Multiple_Unknown_Polyomaviruses_within_the_Human_Population_/726868", "title"=>"Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2013-06-20 01:54:28"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095260"], "description"=>"a<p>Muscle or other tissues from red colobus monkeys partly consumed by chimpanzees.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "polyomavirus"], "article_id"=>726865, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.t001", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sample_material_and_polyomavirus_content_/726865", "title"=>"Sample material and polyomavirus content.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:54:25"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095257"], "description"=>"a<p>number of sera from Germany before, number of plasma samples from Côte d'Ivoire after the slash;</p><p>-, not available.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "german", "sera", "ivorian", "plasma", "samples", "polyomaviruses"], "article_id"=>726863, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.t004", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Seroreactivity_of_German_sera_and_Ivorian_plasma_samples_against_polyomaviruses_by_age_group_/726863", "title"=>"Seroreactivity of German sera and Ivorian plasma samples against polyomaviruses by age group.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:54:23"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095258"], "description"=>"a<p>Before ELISA, 2 µg/ml of VP1 antigen was used for pre-adsorption of antibodies from human sera.</p>b<p>not tested.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "inhibition", "seroreactivity", "chimpanzee"], "article_id"=>726864, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.t005", "stats"=>{"downloads"=>1, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Competitive_inhibition_of_seroreactivity_between_human_and_chimpanzee_polyomaviruses_/726864", "title"=>"Competitive inhibition of seroreactivity between human and chimpanzee polyomaviruses.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:54:24"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095256"], "description"=>"<p>Antibody reactivity was assessed against 4 chimpanzee polyomaviruses (ChPyV, PtrovPyV3, PtrovPyV4 and PtrosPyV2) and 2 human polyomaviruses (HPyV9 and JCPyV) using sera from German (n = 111) and of plasma samples from Ivorian subjects (n = 115). Samples were analysed for seroreactivity with a capsomer-based IgG ELISA using the VP1 major capsid protein of the above polyomaviruses as antigens. The spread of absorbance measurement is shown with green and red dots (representing the German and Ivorian panels, respectively). COVs are shown as solid lines within the graph (COVs of Germans/Ivorians: ChPyV: 0.057/0.034; PtrovPyV3: 0.046/0.070; PtrovPyV4: 0.038/0.012; PtrosPyV2: 0.081/0.080; HPyV9: 0.089/0.066; JCPyV: 0.047/0.079).</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "sera", "vp1", "proteins", "chimpanzee"], "article_id"=>726862, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.g003", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Reactivity_of_human_sera_to_VP1_proteins_of_chimpanzee_and_human_polyomaviruses_/726862", "title"=>"Reactivity of human sera to VP1 proteins of chimpanzee and human polyomaviruses.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-06-20 01:54:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095251"], "description"=>"<p>Polyomaviruses were identified in humans (red), apes (blue), other primates (green), and other mammals and birds (black). Novel polyomaviruses identified in this study are marked with a star and relevant clades to which they belong are highlighted by lettered circles. Viruses from which VP1 was used in serological assays are highlighted by colored rectangles. The human polyomavirus MXPyV has the same phylogenetic position as HPyV10 and is not shown. Support values are given above branches where posterior probability (pp) >0.95 and bootstrap values (Bp) >50. The tree presented is the maximum clade credibility tree. The scale axis is indicated in amino acid substitutions per site.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "chronogram", "deduced", "244", "amino", "alignment", "vp1"], "article_id"=>726859, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.g001", "stats"=>{"downloads"=>1, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Bayesian_chronogram_deduced_from_the_analysis_of_a_244_amino_acid_alignment_of_VP1_sequences_/726859", "title"=>"Bayesian chronogram deduced from the analysis of a 244 amino acid alignment of VP1 sequences.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-06-20 01:54:19"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095262"], "description"=>"a<p>Clades are designated by the same letter code as used in <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003429#ppat-1003429-g001\" target=\"_blank\">Figure 1</a>.</p>b<p>Branch support values are given as posterior probabilities/bootstrap values. The corresponding phylogenetic trees are available as <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003429#ppat-1003429-g001\" target=\"_blank\">Figure 1</a> (VP1), <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003429#ppat.1003429.s006\" target=\"_blank\">Figure S6</a> (VP2) and <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003429#ppat.1003429.s007\" target=\"_blank\">Figure S7</a> (large T).</p>c<p>-: not a clade in the corresponding analysis.</p>d<p>na: not applicable, i.e., none of the novel polyomaviruses included in group g allowed for whole genome recovery.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "clades", "vp2", "phylogenetic"], "article_id"=>726867, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.t003", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Branch_support_values_for_selected_clades_in_VP1_VP2_and_large_T_phylogenetic_analyses_/726867", "title"=>"Branch support values for selected clades in VP1, VP2 and large T phylogenetic analyses.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:54:27"}
  • {"files"=>["https://ndownloader.figshare.com/files/1095261"], "description"=>"a<p>Living conditions: w, wild; c, held in captivity; s, born in the wild but kept in a sanctuary.</p>b<p>DRC = Democratic Republic of Congo.</p>", "links"=>[], "tags"=>["microbiology", "Emerging infectious diseases", "Virology", "Infectious diseases", "Viral diseases", "polyomaviruses", "nonhuman"], "article_id"=>726866, "categories"=>["Medicine", "Biological Sciences"], "users"=>["Nelly Scuda", "Nadege Freda Madinda", "Chantal Akoua-Koffi", "Edgard Valerie Adjogoua", "Diana Wevers", "Jörg Hofmann", "Kenneth N. Cameron", "Siv Aina J. Leendertz", "Emmanuel Couacy-Hymann", "Martha Robbins", "Christophe Boesch", "Michael A. Jarvis", "Ugo Moens", "Lawrence Mugisha", "Sébastien Calvignac-Spencer", "Fabian H. Leendertz", "Bernhard Ehlers"], "doi"=>"https://dx.doi.org/10.1371/journal.ppat.1003429.t002", "stats"=>{"downloads"=>4, "page_views"=>39, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Novel_polyomaviruses_detected_in_nonhuman_primates_/726866", "title"=>"Novel polyomaviruses detected in nonhuman primates.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:54:26"}

PMC Usage Stats | Further Information

  • {"unique-ip"=>"25", "full-text"=>"18", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"35", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"16", "full-text"=>"13", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"51", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"3", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"11", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"5", "pdf"=>"3", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"4", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"7", "cited-by"=>"1", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"30", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"10", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"16", "full-text"=>"17", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"14", "full-text"=>"15", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"10", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"8", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"10", "full-text"=>"32", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"9", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"6", "full-text"=>"13", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"14", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"12", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"8", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"4", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"4", "full-text"=>"11", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"12", "full-text"=>"18", "pdf"=>"15", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"9", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"8", "full-text"=>"12", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}

Relative Metric

{"start_date"=>"2013-01-01T00:00:00Z", "end_date"=>"2013-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[269, 466, 588, 697, 800, 896, 988, 1076, 1165, 1254, 1340, 1417]}, {"subject_area"=>"/Biology and life sciences/Molecular biology", "average_usage"=>[272, 466, 589, 702, 806, 903, 995, 1086, 1176, 1258, 1347, 1422, 1493]}, {"subject_area"=>"/Biology and life sciences/Organisms", "average_usage"=>[281, 484, 611, 728, 835, 934, 1030, 1123, 1214, 1299, 1383, 1464]}, {"subject_area"=>"/Medicine and health sciences", "average_usage"=>[264, 460, 584, 692, 794, 887, 978, 1067, 1154, 1241, 1328, 1408, 1474]}]}
Loading … Spinner
There are currently no alerts