Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine
- Publication Date
- September 04, 2012
- Journal
- PLOS Biology
- Authors
- Christoph Seiler, Gangarao Davuluri, Joshua Abrams, Fitzroy J. Byfield, et al
- Volume
- 10
- Issue
- 9
- Pages
- e1001386
- DOI
- https://dx.plos.org/10.1371/journal.pbio.1001386
- Publisher URL
- http://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.1001386
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/22973180
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433428
- Europe PMC
- http://europepmc.org/abstract/MED/22973180
- Web of Science
- 000309520100001
- Scopus
- 84866708698
- Mendeley
- http://www.mendeley.com/research/smooth-muscle-tension-induces-invasive-remodeling-zebrafish-intestine
Loading … 

Events
Loading … 

CiteULike | Further Information
- {"link"=>{"url"=>"http://www.citeulike.org/group/4585/article/11191132"}, "post_time"=>"2012-09-06 08:12:21", "tag"=>["biology", "biophysics", "cancer"], "linkout"=>{"type"=>"DOI", "url"=>"http://dx.doi.org/10.1371/journal.pbio.1001386"}, "group"=>"GEB", "group_id"=>"4585", "article_id"=>"11191132"}
- {"link"=>{"url"=>"http://www.citeulike.org/user/josedavid/article/11191132"}, "post_time"=>"2012-09-06 08:12:21", "tag"=>["biology", "biophysics", "cancer"], "linkout"=>{"type"=>"DOI", "url"=>"http://dx.doi.org/10.1371/journal.pbio.1001386"}, "username"=>"josedavid", "article_id"=>"11191132"}
- {"link"=>{"url"=>"http://www.citeulike.org/user/delasnievesj/article/11191132"}, "post_time"=>"2012-09-05 21:33:04", "tag"=>"no-tag", "linkout"=>{"type"=>"DOI", "url"=>"http://dx.doi.org/10.1371/journal.pbio.1001386"}, "username"=>"delasnievesj", "article_id"=>"11191132"}
Mendeley | Further Information
{"title"=>"Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine", "type"=>"journal", "authors"=>[{"first_name"=>"Christoph", "last_name"=>"Seiler", "scopus_author_id"=>"36153661900"}, {"first_name"=>"Gangarao", "last_name"=>"Davuluri", "scopus_author_id"=>"25635569600"}, {"first_name"=>"Joshua", "last_name"=>"Abrams", "scopus_author_id"=>"36778630600"}, {"first_name"=>"Fitzroy J.", "last_name"=>"Byfield", "scopus_author_id"=>"55915704500"}, {"first_name"=>"Paul A.", "last_name"=>"Janmey", "scopus_author_id"=>"7005414195"}, {"first_name"=>"Michael", "last_name"=>"Pack", "scopus_author_id"=>"7007055261"}], "year"=>2012, "source"=>"PLoS Biology", "identifiers"=>{"pui"=>"365720695", "isbn"=>"1545-7885", "issn"=>"15449173", "doi"=>"10.1371/journal.pbio.1001386", "scopus"=>"2-s2.0-84866708698", "pmid"=>"22973180", "sgr"=>"84866708698"}, "id"=>"4b320611-fbef-3d6a-93e1-4723e195e3bb", "abstract"=>"The signals that initiate cell invasion are not well understood, but there is increasing evidence that extracellular physical signals play an important role. Here we show that epithelial cell invasion in the intestine of zebrafish meltdown (mlt) mutants arises in response to unregulated contractile tone in the surrounding smooth muscle cell layer. Physical signaling in mlt drives formation of membrane protrusions within the epithelium that resemble invadopodia, matrix-degrading protrusions present in invasive cancer cells. Knockdown of Tks5, a Src substrate that is required for invadopodia formation in mammalian cells blocked formation of the protrusions and rescued invasion in mlt. Activation of Src-signaling induced invadopodia-like protrusions in wild type epithelial cells, however the cells did not migrate into the tissue stroma, thus indicating that the protrusions were required but not sufficient for invasion in this in vivo model. Transcriptional profiling experiments showed that genes responsive to reactive oxygen species (ROS) were upregulated in mlt larvae. ROS generators induced invadopodia-like protrusions and invasion in heterozygous mlt larvae but had no effect in wild type larvae. Co-activation of oncogenic Ras and Wnt signaling enhanced the responsiveness of mlt heterozygotes to the ROS generators. These findings present the first direct evidence that invadopodia play a role in tissue cell invasion in vivo. In addition, they identify an inducible physical signaling pathway sensitive to redox and oncogenic signaling that can drive this process.", "link"=>"http://www.mendeley.com/research/smooth-muscle-tension-induces-invasive-remodeling-zebrafish-intestine", "reader_count"=>45, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>3, "Researcher"=>10, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>11, "Student > Postgraduate"=>3, "Student > Master"=>7, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>3, "Researcher"=>10, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>11, "Student > Postgraduate"=>3, "Student > Master"=>7, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>3, "Biochemistry, Genetics and Molecular Biology"=>5, "Agricultural and Biological Sciences"=>29, "Medicine and Dentistry"=>1, "Neuroscience"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>1, "Social Sciences"=>1, "Computer Science"=>1, "Immunology and Microbiology"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Neuroscience"=>{"Neuroscience"=>2}, "Social Sciences"=>{"Social Sciences"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>29}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>5}, "Unspecified"=>{"Unspecified"=>3}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"United States"=>3}, "group_count"=>3}CrossRef
- http://doi.org/10.3390/antiox7110159
- http://doi.org/10.3390/cancers11050615
- http://doi.org/10.1089/zeb.2013.0919
- http://doi.org/10.1002/hep.28603
- http://doi.org/10.1146/annurev-cellbio-111315-125227
- http://doi.org/10.1016/j.ejcb.2014.10.002
- http://doi.org/10.4161/cam.28406
- http://doi.org/10.4161/cam.28733
- http://doi.org/10.1111/eos.12595
- http://doi.org/10.1089/ars.2015.6266
- http://doi.org/10.1016/j.cub.2019.06.078
- http://doi.org/10.3109/10715762.2015.1110241
- http://doi.org/10.1371/journal.pone.0093496
- http://doi.org/10.1242/dmm.023309
- http://doi.org/10.1016/j.neuint.2017.07.008
- http://doi.org/10.1089/scd.2015.0131
- http://doi.org/10.1083/jcb.201301091
- http://doi.org/10.4161/cam.28833
- http://doi.org/10.1016/j.bbrc.2015.03.119
- http://doi.org/10.1093/hmg/ddy218
- http://doi.org/10.4161/cam.28349
- http://doi.org/10.1371/journal.pone.0131908
- http://doi.org/10.3389/fcell.2015.00004
- http://doi.org/10.1016/j.tcb.2016.08.003
- http://doi.org/10.4161/worm.26169
- http://doi.org/10.1083/jcb.201311112
- http://doi.org/10.1016/j.ejcb.2016.06.006
- http://doi.org/10.1152/ajpregu.00225.2015
- http://doi.org/10.1016/j.matbio.2016.06.007
- http://doi.org/10.1021/acsnano.5b03157
- http://doi.org/10.1016/j.ydbio.2016.03.011
- http://doi.org/10.1371/journal.pgen.1005786
- http://doi.org/10.1242/jcs.182329
- http://doi.org/10.1089/ars.2017.7469
- http://doi.org/10.1515/hsz-2014-0294
Europe PMC Database Citations | Further Information
{"UNIPROT"=>4}Scopus | Further Information
{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84866708698"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84866708698?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866708698&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84866708698&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84866708698", "dc:identifier"=>"SCOPUS_ID:84866708698", "eid"=>"2-s2.0-84866708698", "dc:title"=>"Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine", "dc:creator"=>"Seiler C.", "prism:publicationName"=>"PLoS Biology", "prism:issn"=>"15449173", "prism:eIssn"=>"15457885", "prism:volume"=>"10", "prism:issueIdentifier"=>"9", "prism:pageRange"=>nil, "prism:coverDate"=>"2012-09-01", "prism:coverDisplayDate"=>"September 2012", "prism:doi"=>"10.1371/journal.pbio.1001386", "citedby-count"=>"38", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Pennsylvania, School of Medicine", "affiliation-city"=>"Philadelphia", "affiliation-country"=>"United States"}], "pubmed-id"=>"22973180", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1001386", "source-id"=>"12977", "openaccess"=>"1", "openaccessFlag"=>true}- {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosbiology%2Farticle%3Fid%3D10.1371%252Fjournal.pbio.1001386", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}
- {"id"=>"243095101239341056", "text"=>"Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine: by Christoph Seiler, Gangarao Davu... http://t.co/CXjtuXLC", "created_at"=>"2012-09-04T21:16:03Z", "user"=>"Hortusrarus", "user_name"=>"Hortus rarus", "user_profile_image"=>"http://a0.twimg.com/sticky/default_profile_images/default_profile_6_normal.png"}
- {"id"=>"243146142597124096", "text"=>"Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine http://t.co/KZ0IlquT", "created_at"=>"2012-09-05T00:38:52Z", "user"=>"ScienceEnabled", "user_name"=>"Science Enabled", "user_profile_image"=>"http://a0.twimg.com/profile_images/1579522693/scienceenabled-star_normal.png"}
- {"id"=>"243417328304410625", "text"=>"Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine. http://t.co/DfegLzXC #Morpholino", "created_at"=>"2012-09-05T18:36:28Z", "user"=>"jonmoulton", "user_name"=>"Jon D. Moulton", "user_profile_image"=>"http://a0.twimg.com/profile_images/1149621273/PortraitDali07b_normal.jpg"}
- {"id"=>"243417536186683393", "text"=>"RT @jonmoulton: Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine. http://t.co/DfegLzXC #Morpholino", "created_at"=>"2012-09-05T18:37:17Z", "user"=>"GeneTools", "user_name"=>"Gene Tools support", "user_profile_image"=>"http://a0.twimg.com/profile_images/1586973198/TwitterAvatar_normal.gif"}
- {"id"=>"243511222941671424", "text"=>"#PLOS http://t.co/KMhPJG6U first in vivo evidence of invadopodia..i\"n tissue cell invasion\"..links to redox and oncogenic signaling..", "created_at"=>"2012-09-06T00:49:34Z", "user"=>"balapagos", "user_name"=>"Bala Iyengar", "user_profile_image"=>"http://a0.twimg.com/profile_images/2496236366/1znwftliitwwaech84pu_normal.png"}
- {"id"=>"243511417494437888", "text"=>"#PLOS http://t.co/KMhPJG6U first in vivo evidence of invadopodia..\"in tissue cell invasion\"..links to redox and oncogenic signaling..", "created_at"=>"2012-09-06T00:50:20Z", "user"=>"balapagos", "user_name"=>"Bala Iyengar", "user_profile_image"=>"http://a0.twimg.com/profile_images/2496236366/1znwftliitwwaech84pu_normal.png"}
- {"id"=>"244779175788048384", "text"=>"PLoS Biology: Smooth Muscle Tension Induces Invasive ...: PLoS Biology is an open-access, peer-reviewed journal ... http://t.co/VrB0LiYI", "created_at"=>"2012-09-09T12:47:57Z", "user"=>"freddykyoung", "user_name"=>"fred young", "user_profile_image"=>"http://a0.twimg.com/profile_images/848589322/42-18982327_normal.JPG"}
- {"id"=>"245086275613384704", "text"=>"Cilia sense tissue pressure http://t.co/mXa07cPA @BPoD_mrc; see also http://t.co/URQzV96Y in @PLOSBiology for more on mech. forces in cancer", "created_at"=>"2012-09-10T09:08:16Z", "user"=>"CARISA_ZA", "user_name"=>"CARISA", "user_profile_image"=>"http://a0.twimg.com/profile_images/2402276573/51a61fki0y0e9y7bx85v_normal.jpeg"}
Wikipedia | Further Information
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s011.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s011.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s009.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s009.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s013.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s013.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s016.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s016.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s010.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s010.ogv", "timestamp"=>"2017-02-11T14:03:58Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s008.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s008.ogv", "timestamp"=>"2017-02-11T14:03:58Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s015.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s015.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s014.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s014.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s012.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s012.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
- {"title"=>"File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s017.ogv", "url"=>"http://commons.wikimedia.org/wiki/File:Smooth-Muscle-Tension-Induces-Invasive-Remodeling-of-the-Zebrafish-Intestine-pbio.1001386.s017.ogv", "timestamp"=>"2017-02-11T14:03:59Z"}
Counter
- {"month"=>"9", "year"=>"2012", "pdf_views"=>"339", "xml_views"=>"79", "html_views"=>"3961"}
- {"month"=>"10", "year"=>"2012", "pdf_views"=>"128", "xml_views"=>"18", "html_views"=>"1076"}
- {"month"=>"11", "year"=>"2012", "pdf_views"=>"44", "xml_views"=>"6", "html_views"=>"362"}
- {"month"=>"12", "year"=>"2012", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"151"}
- {"month"=>"1", "year"=>"2013", "pdf_views"=>"27", "xml_views"=>"3", "html_views"=>"186"}
- {"month"=>"2", "year"=>"2013", "pdf_views"=>"26", "xml_views"=>"5", "html_views"=>"272"}
- {"month"=>"3", "year"=>"2013", "pdf_views"=>"20", "xml_views"=>"2", "html_views"=>"106"}
- {"month"=>"4", "year"=>"2013", "pdf_views"=>"15", "xml_views"=>"2", "html_views"=>"98"}
- {"month"=>"5", "year"=>"2013", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"91"}
- {"month"=>"6", "year"=>"2013", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"103"}
- {"month"=>"7", "year"=>"2013", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"103"}
- {"month"=>"8", "year"=>"2013", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"72"}
- {"month"=>"9", "year"=>"2013", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"152"}
- {"month"=>"10", "year"=>"2013", "pdf_views"=>"13", "xml_views"=>"3", "html_views"=>"247"}
- {"month"=>"11", "year"=>"2013", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"65"}
- {"month"=>"12", "year"=>"2013", "pdf_views"=>"10", "xml_views"=>"3", "html_views"=>"183"}
- {"month"=>"1", "year"=>"2014", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"154"}
- {"month"=>"2", "year"=>"2014", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"233"}
- {"month"=>"3", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"275"}
- {"month"=>"4", "year"=>"2014", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"258"}
- {"month"=>"5", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"141"}
- {"month"=>"6", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"85"}
- {"month"=>"7", "year"=>"2014", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"113"}
- {"month"=>"8", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"79"}
- {"month"=>"9", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"56"}
- {"month"=>"10", "year"=>"2014", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"101"}
- {"month"=>"11", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"99"}
- {"month"=>"12", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"4", "html_views"=>"75"}
- {"month"=>"1", "year"=>"2015", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"94"}
- {"month"=>"2", "year"=>"2015", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"50"}
- {"month"=>"3", "year"=>"2015", "pdf_views"=>"45", "xml_views"=>"0", "html_views"=>"50"}
- {"month"=>"4", "year"=>"2015", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"46"}
- {"month"=>"5", "year"=>"2015", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"51"}
- {"month"=>"6", "year"=>"2015", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"46"}
- {"month"=>"7", "year"=>"2015", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"52"}
- {"month"=>"8", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"43"}
- {"month"=>"9", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"38"}
- {"month"=>"10", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"59"}
- {"month"=>"11", "year"=>"2015", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"31"}
- {"month"=>"12", "year"=>"2015", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"47"}
- {"month"=>"1", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"60"}
- {"month"=>"2", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"40"}
- {"month"=>"3", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"51"}
- {"month"=>"4", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"77"}
- {"month"=>"5", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"81"}
- {"month"=>"6", "year"=>"2016", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"50"}
- {"month"=>"7", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"37"}
- {"month"=>"8", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"41"}
- {"month"=>"9", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"54"}
- {"month"=>"10", "year"=>"2016", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"41"}
- {"month"=>"11", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"50"}
- {"month"=>"12", "year"=>"2016", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"26"}
- {"month"=>"1", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"33"}
- {"month"=>"2", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"33"}
- {"month"=>"3", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"28"}
- {"month"=>"4", "year"=>"2017", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"56"}
- {"month"=>"5", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"54"}
- {"month"=>"6", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"36"}
- {"month"=>"7", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"40"}
- {"month"=>"8", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"32"}
- {"month"=>"9", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"35"}
- {"month"=>"10", "year"=>"2017", "pdf_views"=>"10", "xml_views"=>"3", "html_views"=>"38"}
- {"month"=>"11", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"86"}
- {"month"=>"12", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"13"}
- {"month"=>"1", "year"=>"2018", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"36"}
- {"month"=>"2", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"1", "html_views"=>"35"}
- {"month"=>"3", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
- {"month"=>"4", "year"=>"2018", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"9"}
- {"month"=>"5", "year"=>"2018", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"18"}
- {"month"=>"6", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"16"}
- {"month"=>"7", "year"=>"2018", "pdf_views"=>"9", "xml_views"=>"4", "html_views"=>"42"}
- {"month"=>"8", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"16"}
- {"month"=>"9", "year"=>"2018", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"17"}
- {"month"=>"10", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"4", "html_views"=>"12"}
- {"month"=>"11", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"7"}
- {"month"=>"12", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"14"}
- {"month"=>"1", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"20"}
- {"month"=>"2", "year"=>"2019", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"16"}
- {"month"=>"3", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"6"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"9"}
- {"month"=>"5", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"9"}
- {"month"=>"6", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"9"}
- {"month"=>"7", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"10"}
- {"month"=>"8", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}
- {"month"=>"9", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"5"}
- {"month"=>"10", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"9"}
- {"month"=>"11", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"5"}
- {"month"=>"12", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"4"}
PMC Usage Stats | Further Information
- {"unique-ip"=>"51", "full-text"=>"48", "pdf"=>"35", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
- {"unique-ip"=>"43", "full-text"=>"41", "pdf"=>"20", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"20", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
- {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
- {"unique-ip"=>"24", "full-text"=>"21", "pdf"=>"4", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"18", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
- {"unique-ip"=>"14", "full-text"=>"18", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
- {"unique-ip"=>"16", "full-text"=>"22", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
- {"unique-ip"=>"13", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
- {"unique-ip"=>"26", "full-text"=>"18", "pdf"=>"12", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"61", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
- {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
- {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
- {"unique-ip"=>"16", "full-text"=>"13", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
- {"unique-ip"=>"12", "full-text"=>"13", "pdf"=>"1", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
- {"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"25", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
- {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
- {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
- {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
- {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
- {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"1", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
- {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
- {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"5", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
- {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"4"}
- {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
- {"unique-ip"=>"8", "full-text"=>"3", "pdf"=>"1", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
- {"unique-ip"=>"18", "full-text"=>"8", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
- {"unique-ip"=>"22", "full-text"=>"7", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"10", "cited-by"=>"1", "year"=>"2014", "month"=>"10"}
- {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
- {"unique-ip"=>"12", "full-text"=>"6", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
- {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
- {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
- {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
- {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
- {"unique-ip"=>"11", "full-text"=>"14", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
- {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
- {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
- {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
- {"unique-ip"=>"11", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
- {"unique-ip"=>"10", "full-text"=>"6", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
- {"unique-ip"=>"16", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
- {"unique-ip"=>"15", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"2"}
- {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
- {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
- {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
- {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
- {"unique-ip"=>"11", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
- {"unique-ip"=>"8", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
- {"unique-ip"=>"14", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
- {"unique-ip"=>"14", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
- {"unique-ip"=>"7", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
- {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2017", "month"=>"1"}
- {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
- {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
- {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
- {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
- {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
- {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
- {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
- {"unique-ip"=>"11", "full-text"=>"14", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
- {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
- {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
- {"unique-ip"=>"38", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"29", "cited-by"=>"1", "year"=>"2017", "month"=>"12"}
- {"unique-ip"=>"15", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
- {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
- {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
- {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
- {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
- {"unique-ip"=>"2", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
- {"unique-ip"=>"14", "full-text"=>"6", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
- {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
- {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
- {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
- {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
- {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
- {"unique-ip"=>"7", "full-text"=>"10", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
- {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
- {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
- {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
- {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
Relative Metric
{"start_date"=>"2012-01-01T00:00:00Z", "end_date"=>"2012-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences/Anatomy", "average_usage"=>[308, 530, 649, 751, 844, 933, 1021, 1107, 1194, 1277, 1357, 1426, 1501, 1572, 1634, 1702, 1768, 1838, 1910, 1976, 2046, 2114, 2181, 2241, 2298]}, {"subject_area"=>"/Biology and life sciences/Anatomy and physiology", "average_usage"=>[307, 540, 660, 756, 847, 936, 1025, 1111, 1199, 1282, 1361, 1432]}, {"subject_area"=>"/Biology and life sciences/Developmental biology", "average_usage"=>[313, 562, 690, 796, 893, 986, 1079, 1173, 1257, 1349, 1429, 1506, 1586, 1661, 1730, 1803, 1876, 1945, 2017, 2091, 2163, 2225, 2294, 2362, 2430]}, {"subject_area"=>"/Biology and life sciences/Organisms", "average_usage"=>[331, 557, 677, 777, 868, 960, 1050, 1136, 1223, 1307, 1390, 1466, 1536, 1603, 1673, 1741, 1814, 1889, 1954, 2028, 2096, 2164, 2233, 2305, 2362]}, {"subject_area"=>"/Biology and life sciences/Physiology", "average_usage"=>[307, 536, 653, 753, 839, 926, 1017, 1103, 1189, 1268, 1348, 1425, 1492, 1557, 1620, 1686, 1759, 1825, 1891, 1950, 2014, 2079, 2141, 2200, 2255]}, {"subject_area"=>"/Medicine and health sciences/Anatomy", "average_usage"=>[307, 529, 649, 751, 845, 936, 1025, 1113, 1197, 1284, 1360, 1432, 1501, 1570, 1632, 1697, 1765, 1834, 1904, 1972, 2041, 2107, 2170, 2231, 2292]}]}Loading … 

There are currently no alerts