Revised Estimates for the Number of Human and Bacteria Cells in the Body
Publication Date
August 19, 2016
Journal
PLOS Biology
Authors
Ron Sender, Shai Fuchs & Ron Milo
Volume
14
Issue
8
Pages
e1002533
DOI
https://dx.plos.org/10.1371/journal.pbio.1002533
Publisher URL
http://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.1002533
Web of Science
000382395700009
Scopus
84988864262
Mendeley
http://www.mendeley.com/research/revised-estimates-number-human-bacteria-cells-body-1
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Mendeley | Further Information

{"title"=>"Revised Estimates for the Number of Human and Bacteria Cells in the Body", "type"=>"journal", "authors"=>[{"first_name"=>"Ron", "last_name"=>"Sender", "scopus_author_id"=>"57188268600"}, {"first_name"=>"Shai", "last_name"=>"Fuchs", "scopus_author_id"=>"56454818800"}, {"first_name"=>"Ron", "last_name"=>"Milo", "scopus_author_id"=>"57188697178"}], "year"=>2016, "source"=>"PLoS Biology", "identifiers"=>{"pui"=>"612326802", "sgr"=>"84988864262", "issn"=>"15457885", "arxiv"=>"036103", "pmid"=>"25246403", "scopus"=>"2-s2.0-84988864262", "doi"=>"10.1371/journal.pbio.1002533", "isbn"=>"9788578110796"}, "id"=>"66e9c7ba-3052-3e65-8ff1-5bb08f4f79c7", "abstract"=>"We critically revisit the ″common knowledge″ that bacteria outnumber human cells by a ratio of at least 10:1 in the human body. We found the total number of bacteria in the ″reference man″ to be 3.9·1013, with an uncertainty (SEM) of 25%, and a variation over the population (CV) of 52%. For human cells we identify the dominant role of the hematopoietic lineage to the total count of body cells (≈90%), and revise past estimates to reach a total of 3.0·1013 human cells in the 70 kg ″reference man″ with 2% uncertainty and 14% CV. Our analysis updates the widely-cited 10:1 ratio, showing that the number of bacteria in our bodies is actually of the same order as the number of human cells. Indeed, the numbers are similar enough that each defecation event may flip the ratio to favor human cells over bacteria.", "link"=>"http://www.mendeley.com/research/revised-estimates-number-human-bacteria-cells-body-1", "reader_count"=>1133, "reader_count_by_academic_status"=>{"Unspecified"=>41, "Professor > Associate Professor"=>38, "Librarian"=>1, "Researcher"=>206, "Student > Doctoral Student"=>57, "Student > Ph. D. 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