Mendeley | Further Information

{"title"=>"Animal Study Registries: Results from a Stakeholder Analysis on Potential Strengths, Weaknesses, Facilitators, and Barriers", "type"=>"journal", "authors"=>[{"first_name"=>"Susanne", "last_name"=>"Wieschowski", "scopus_author_id"=>"57189707867"}, {"first_name"=>"Diego S.", "last_name"=>"Silva", "scopus_author_id"=>"35738098800"}, {"first_name"=>"Daniel", "last_name"=>"Strech", "scopus_author_id"=>"23019920500"}], "year"=>2016, "source"=>"PLoS Biology", "identifiers"=>{"pmid"=>"27832101", "doi"=>"10.1371/journal.pbio.2000391", "pui"=>"613901520", "issn"=>"15457885", "sgr"=>"85007410687", "scopus"=>"2-s2.0-85007410687"}, "id"=>"e237cc7d-1c8f-3a5f-a37b-a19736228aec", "abstract"=>"Publication bias in animal research, its extent, its predictors, and its potential countermeasures are increasingly discussed. Recent reports and conferences highlight the potential strengths of animal study registries (ASRs) in this regard. Others have warned that prospective registration of animal studies could diminish creativity, add administrative burdens, and complicate intellectual property issues in translational research. A literature review and 21 international key-informant interviews were conducted and thematically analyzed to develop a comprehensive matrix of main- and subcategories for potential ASR-related strengths, weaknesses, facilitators, and barriers (SWFBs). We identified 130 potential SWFBs. All stakeholder groups agreed that ASRs could in various ways improve the quality and refinement of animal studies while allowing their number to be reduced, as well as supporting meta-research on animal studies. However, all stakeholder groups also highlighted the potential for theft of ideas, higher administrative burdens, and reduced creativity and serendipity in animal studies. Much more detailed reasoning was captured in the interviews than is currently found in the literature, providing a comprehensive account of the issues and arguments around ASRs. All stakeholder groups highlighted compelling potential strengths of ASRs. Although substantial weaknesses and implementation barriers were highlighted as well, different governance measures might help to minimize or even eliminate their impact. Such measures might include confidentiality time frames for accessing prospectively registered protocols, harmonized reporting requirements across ASRs, ethics reviews, lab notebooks, and journal submissions. The comprehensive information gathered in this study could help to guide a more evidence-based debate and to design pilot tests for ASRs.", "link"=>"http://www.mendeley.com/research/animal-study-registries-results-stakeholder-analysis-potential-strengths-weaknesses-facilitators-bar", "reader_count"=>11, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Researcher"=>2, "Student > Ph. D. Student"=>2, "Other"=>2, "Student > Bachelor"=>1, "Professor"=>1, "Lecturer"=>1, "Student > Master"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Researcher"=>2, "Student > Ph. D. Student"=>2, "Other"=>2, "Student > Bachelor"=>1, "Professor"=>1, "Lecturer"=>1, "Student > Master"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Agricultural and Biological Sciences"=>4, "Medicine and Dentistry"=>4, "Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>4}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>4}, "Unspecified"=>{"Unspecified"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"United Kingdom"=>2, "Switzerland"=>1, "Germany"=>1}, "group_count"=>0}

CrossRef

• http://doi.org/10.1007/s00281-017-0622-4
• http://doi.org/10.1371/journal.pbio.2003217
• http://doi.org/10.1093/beheco/arx005
• http://doi.org/10.1111/bph.14485
• http://doi.org/10.1016/j.tibtech.2017.12.001
• http://doi.org/10.1371/journal.pone.0223758
• http://doi.org/10.1136/bmjos-2018-000048
• http://doi.org/10.1371/journal.pbio.3000463
• http://doi.org/10.1371/journal.pone.0226443
• http://doi.org/10.1371/journal.pbio.2004879

Scopus | Further Information

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Web of Science®

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Journal Comments

Twitter

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• {"id"=>"803880077083680768", "text"=>"RT @Strech_Daniel: Our work on registries for #animalresearch https://t.co/uzIvmhcigj in a Q/A feature by @David_Grimm https://t.co/xeIDrkh…", "created_at"=>"2016-11-30T08:35:20Z", "user"=>"trished", "user_name"=>"Trish Groves", "user_profile_image"=>"http://pbs.twimg.com/profile_images/737630194257661952/648PVMij_normal.jpg"}
• {"id"=>"804781653860225024", "text"=>"RT @Strech_Daniel: Our work on registries for #animalresearch https://t.co/uzIvmhcigj in a Q/A feature by @David_Grimm https://t.co/xeIDrkh…", "created_at"=>"2016-12-02T20:17:53Z", "user"=>"m_waligora", "user_name"=>"Marcin Walig?ra", "user_profile_image"=>"http://pbs.twimg.com/profile_images/770918365221314561/oqaNU7li_normal.jpg"}
• {"id"=>"807680566405529600", "text"=>"RT @Strech_Daniel: Our work on registries for #animalresearch https://t.co/uzIvmhcigj in a Q/A feature by @David_Grimm… ", "created_at"=>"2016-12-10T20:17:07Z", "user"=>"rodrigonunescal", "user_name"=>"Rodrigo Nunes Cal", "user_profile_image"=>"http://pbs.twimg.com/profile_images/788678581765414912/uRShGKcj_normal.jpg"}
• {"id"=>"807683699781332992", "text"=>"RT @Strech_Daniel: Our new paper https://t.co/uzIvmhcigj strenghts and weaknesses of registries for #animalresearch @PLOSBiology @rewardall…", "created_at"=>"2016-12-10T20:29:34Z", "user"=>"rodrigonunescal", "user_name"=>"Rodrigo Nunes Cal", "user_profile_image"=>"http://pbs.twimg.com/profile_images/788678581765414912/uRShGKcj_normal.jpg"}
• {"id"=>"811222895573737472", "text"=>"Plenty of reasons (excuses) in this paper why researchers resist having a register of #animaltrials #researchwaste https://t.co/F4KXyL6S2E", "created_at"=>"2016-12-20T14:53:04Z", "user"=>"SABREresearchUK", "user_name"=>"SABRE Research UK", "user_profile_image"=>"http://pbs.twimg.com/profile_images/474616712650698752/7HHxjQYn_normal.jpeg"}

Wikipedia

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PMC Usage Stats

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• {"unique-ip"=>"19", "full-text"=>"19", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
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F1000Prime