Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges
- Publication Date
- February 23, 2012
- Journal
- PLOS Computational Biology
- Authors
- Purvesh Khatri, Marina Sirota & Atul J. Butte
- Volume
- 8
- Issue
- 2
- Pages
- e1002375
- DOI
- https://dx.plos.org/10.1371/journal.pcbi.1002375
- Publisher URL
- http://journals.plos.org/ploscompbiol/article?id=10.1371%2Fjournal.pcbi.1002375
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/22383865
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285573
- Europe PMC
- http://europepmc.org/abstract/MED/22383865
- Web of Science
- 000300729900019
- Scopus
- 84861123691
- Mendeley
- http://www.mendeley.com/research/ten-years-pathway-analysis-current-approaches-outstanding-challenges-1
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Mendeley | Further Information
{"title"=>"Ten years of pathway analysis: Current approaches and outstanding challenges", "type"=>"generic", "authors"=>[{"first_name"=>"Purvesh", "last_name"=>"Khatri", "scopus_author_id"=>"7004042184"}, {"first_name"=>"Marina", "last_name"=>"Sirota", "scopus_author_id"=>"23971815700"}, {"first_name"=>"Atul J.", "last_name"=>"Butte", "scopus_author_id"=>"7003333396"}], "year"=>2012, "source"=>"PLoS Computational Biology", "identifiers"=>{"scopus"=>"2-s2.0-84861123691", "sgr"=>"84861123691", "issn"=>"1553734X", "doi"=>"10.1371/journal.pcbi.1002375", "pmid"=>"22383865", "isbn"=>"1553-7358 (Electronic)\\r1553-734X (Linking)", "pui"=>"364830968"}, "id"=>"cdff2aa7-8305-3916-9806-a98e59781124", "abstract"=>"Pathway analysis has become the first choice for gaining insight into the underlying biology of differentially expressed genes and proteins, as it reduces complexity and has increased explanatory power. We discuss the evolution of knowledge base-driven pathway analysis over its first decade, distinctly divided into three generations. We also discuss the limitations that are specific to each generation, and how they are addressed by successive generations of methods. We identify a number of annotation challenges that must be addressed to enable development of the next generation of pathway analysis methods. Furthermore, we identify a number of methodological challenges that the next generation of methods must tackle to take advantage of the technological advances in genomics and proteomics in order to improve specificity, sensitivity, and relevance of pathway analysis.", "link"=>"http://www.mendeley.com/research/ten-years-pathway-analysis-current-approaches-outstanding-challenges-1", "reader_count"=>1507, "reader_count_by_academic_status"=>{"Unspecified"=>26, "Professor > Associate Professor"=>84, "Librarian"=>5, "Researcher"=>419, "Student > Doctoral Student"=>64, "Student > Ph. D. 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Scopus | Further Information
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Article Coverage Curated
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- {"month"=>"12", "year"=>"2016", "pdf_views"=>"232", "xml_views"=>"2", "html_views"=>"1022"}
- {"month"=>"1", "year"=>"2017", "pdf_views"=>"234", "xml_views"=>"1", "html_views"=>"1182"}
- {"month"=>"2", "year"=>"2017", "pdf_views"=>"306", "xml_views"=>"4", "html_views"=>"1260"}
- {"month"=>"3", "year"=>"2017", "pdf_views"=>"345", "xml_views"=>"2", "html_views"=>"1253"}
- {"month"=>"4", "year"=>"2017", "pdf_views"=>"257", "xml_views"=>"2", "html_views"=>"1044"}
- {"month"=>"5", "year"=>"2017", "pdf_views"=>"255", "xml_views"=>"6", "html_views"=>"903"}
- {"month"=>"6", "year"=>"2017", "pdf_views"=>"265", "xml_views"=>"3", "html_views"=>"1016"}
- {"month"=>"7", "year"=>"2017", "pdf_views"=>"279", "xml_views"=>"0", "html_views"=>"868"}
- {"month"=>"8", "year"=>"2017", "pdf_views"=>"216", "xml_views"=>"5", "html_views"=>"872"}
- {"month"=>"9", "year"=>"2017", "pdf_views"=>"194", "xml_views"=>"1", "html_views"=>"779"}
- {"month"=>"10", "year"=>"2017", "pdf_views"=>"219", "xml_views"=>"4", "html_views"=>"934"}
- {"month"=>"11", "year"=>"2017", "pdf_views"=>"266", "xml_views"=>"3", "html_views"=>"1096"}
- {"month"=>"12", "year"=>"2017", "pdf_views"=>"227", "xml_views"=>"3", "html_views"=>"802"}
- {"month"=>"1", "year"=>"2018", "pdf_views"=>"223", "xml_views"=>"0", "html_views"=>"788"}
- {"month"=>"2", "year"=>"2018", "pdf_views"=>"330", "xml_views"=>"3", "html_views"=>"536"}
- {"month"=>"3", "year"=>"2018", "pdf_views"=>"355", "xml_views"=>"2", "html_views"=>"620"}
- {"month"=>"4", "year"=>"2018", "pdf_views"=>"384", "xml_views"=>"2", "html_views"=>"594"}
- {"month"=>"5", "year"=>"2018", "pdf_views"=>"456", "xml_views"=>"4", "html_views"=>"617"}
- {"month"=>"6", "year"=>"2018", "pdf_views"=>"457", "xml_views"=>"1", "html_views"=>"547"}
- {"month"=>"7", "year"=>"2018", "pdf_views"=>"523", "xml_views"=>"4", "html_views"=>"612"}
- {"month"=>"8", "year"=>"2018", "pdf_views"=>"398", "xml_views"=>"2", "html_views"=>"533"}
- {"month"=>"9", "year"=>"2018", "pdf_views"=>"310", "xml_views"=>"2", "html_views"=>"416"}
- {"month"=>"10", "year"=>"2018", "pdf_views"=>"391", "xml_views"=>"5", "html_views"=>"648"}
- {"month"=>"11", "year"=>"2018", "pdf_views"=>"326", "xml_views"=>"0", "html_views"=>"524"}
- {"month"=>"12", "year"=>"2018", "pdf_views"=>"268", "xml_views"=>"1", "html_views"=>"464"}
- {"month"=>"1", "year"=>"2019", "pdf_views"=>"277", "xml_views"=>"1", "html_views"=>"610"}
- {"month"=>"2", "year"=>"2019", "pdf_views"=>"217", "xml_views"=>"1", "html_views"=>"418"}
- {"month"=>"3", "year"=>"2019", "pdf_views"=>"224", "xml_views"=>"4", "html_views"=>"495"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"271", "xml_views"=>"1", "html_views"=>"561"}
- {"month"=>"5", "year"=>"2019", "pdf_views"=>"201", "xml_views"=>"0", "html_views"=>"519"}
- {"month"=>"6", "year"=>"2019", "pdf_views"=>"176", "xml_views"=>"0", "html_views"=>"391"}
- {"month"=>"7", "year"=>"2019", "pdf_views"=>"219", "xml_views"=>"3", "html_views"=>"510"}
- {"month"=>"8", "year"=>"2019", "pdf_views"=>"153", "xml_views"=>"0", "html_views"=>"327"}
- {"month"=>"9", "year"=>"2019", "pdf_views"=>"182", "xml_views"=>"0", "html_views"=>"340"}
- {"month"=>"10", "year"=>"2019", "pdf_views"=>"158", "xml_views"=>"1", "html_views"=>"378"}
- {"month"=>"11", "year"=>"2019", "pdf_views"=>"313", "xml_views"=>"1", "html_views"=>"485"}
- {"month"=>"12", "year"=>"2019", "pdf_views"=>"265", "xml_views"=>"0", "html_views"=>"394"}
- {"month"=>"1", "year"=>"2020", "pdf_views"=>"253", "xml_views"=>"0", "html_views"=>"336"}
- {"month"=>"2", "year"=>"2020", "pdf_views"=>"209", "xml_views"=>"2", "html_views"=>"427"}
- {"month"=>"3", "year"=>"2020", "pdf_views"=>"305", "xml_views"=>"2", "html_views"=>"320"}
- {"month"=>"4", "year"=>"2020", "pdf_views"=>"332", "xml_views"=>"1", "html_views"=>"487"}
- {"month"=>"5", "year"=>"2020", "pdf_views"=>"400", "xml_views"=>"0", "html_views"=>"377"}
- {"month"=>"6", "year"=>"2020", "pdf_views"=>"289", "xml_views"=>"0", "html_views"=>"311"}
- {"month"=>"7", "year"=>"2020", "pdf_views"=>"498", "xml_views"=>"2", "html_views"=>"355"}
- {"month"=>"8", "year"=>"2020", "pdf_views"=>"155", "xml_views"=>"1", "html_views"=>"313"}
- {"month"=>"9", "year"=>"2020", "pdf_views"=>"296", "xml_views"=>"1", "html_views"=>"493"}
- {"month"=>"10", "year"=>"2020", "pdf_views"=>"212", "xml_views"=>"1", "html_views"=>"416"}
- {"month"=>"11", "year"=>"2020", "pdf_views"=>"303", "xml_views"=>"4", "html_views"=>"441"}
- {"month"=>"12", "year"=>"2020", "pdf_views"=>"237", "xml_views"=>"4", "html_views"=>"315"}
- {"month"=>"1", "year"=>"2021", "pdf_views"=>"179", "xml_views"=>"0", "html_views"=>"357"}
PMC Usage Stats | Further Information
- {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"126", "unique-ip"=>"114", "pdf"=>"90", "year"=>"2012", "figure"=>"21", "scanned-summary"=>"0", "supp-data"=>"34"}
- {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"79", "year"=>"2012", "pdf"=>"60", "unique-ip"=>"73", "figure"=>"22", "scanned-summary"=>"0", "supp-data"=>"22"}
- {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"69", "unique-ip"=>"61", "pdf"=>"44", "year"=>"2012", "figure"=>"18", "scanned-summary"=>"0", "supp-data"=>"26"}
- {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"74", "year"=>"2012", "pdf"=>"50", "unique-ip"=>"72", "figure"=>"21", "scanned-summary"=>"0", "supp-data"=>"6"}
- {"unique-ip"=>"84", "full-text"=>"89", "pdf"=>"60", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"16", "cited-by"=>"3", "year"=>"2012", "month"=>"7"}
- {"unique-ip"=>"70", "full-text"=>"72", "pdf"=>"43", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
- {"unique-ip"=>"65", "full-text"=>"72", "pdf"=>"32", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"15", "cited-by"=>"1", "year"=>"2012", "month"=>"9"}
- {"unique-ip"=>"61", "full-text"=>"51", "pdf"=>"41", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
- {"unique-ip"=>"34", "full-text"=>"36", "pdf"=>"9", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
- {"unique-ip"=>"47", "full-text"=>"44", "pdf"=>"31", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"7", "cited-by"=>"1", "year"=>"2013", "month"=>"1"}
- {"unique-ip"=>"39", "full-text"=>"36", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
- {"unique-ip"=>"70", "full-text"=>"73", "pdf"=>"33", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
- {"unique-ip"=>"45", "full-text"=>"38", "pdf"=>"22", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
- {"unique-ip"=>"40", "full-text"=>"39", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2012", "month"=>"11"}
- {"unique-ip"=>"43", "full-text"=>"43", "pdf"=>"23", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
- {"unique-ip"=>"33", "full-text"=>"26", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
- {"unique-ip"=>"38", "full-text"=>"36", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"12", "cited-by"=>"2", "year"=>"2013", "month"=>"7"}
- {"unique-ip"=>"33", "full-text"=>"32", "pdf"=>"20", "abstract"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"2", "year"=>"2013", "month"=>"8"}
- {"unique-ip"=>"39", "full-text"=>"49", "pdf"=>"29", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
- {"unique-ip"=>"52", "full-text"=>"48", "pdf"=>"28", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2013", "month"=>"10"}
- {"unique-ip"=>"31", "full-text"=>"22", "pdf"=>"22", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
- {"unique-ip"=>"36", "full-text"=>"42", "pdf"=>"16", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
- {"unique-ip"=>"51", "full-text"=>"55", "pdf"=>"40", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
- {"unique-ip"=>"40", "full-text"=>"34", "pdf"=>"27", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
- {"unique-ip"=>"36", "full-text"=>"44", "pdf"=>"20", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"5", "cited-by"=>"1", "year"=>"2014", "month"=>"3"}
- {"unique-ip"=>"37", "full-text"=>"38", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
- {"unique-ip"=>"48", "full-text"=>"46", "pdf"=>"18", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
- {"unique-ip"=>"36", "full-text"=>"40", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
- {"unique-ip"=>"59", "full-text"=>"55", "pdf"=>"30", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
- {"unique-ip"=>"46", "full-text"=>"41", "pdf"=>"25", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"21", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
- {"unique-ip"=>"65", "full-text"=>"42", "pdf"=>"21", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"23", "cited-by"=>"2", "year"=>"2014", "month"=>"9"}
- {"unique-ip"=>"47", "full-text"=>"30", "pdf"=>"15", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"18", "cited-by"=>"1", "year"=>"2014", "month"=>"10"}
- {"unique-ip"=>"40", "full-text"=>"31", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"20", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
- {"unique-ip"=>"30", "full-text"=>"20", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"18", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
- {"unique-ip"=>"78", "full-text"=>"75", "pdf"=>"33", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"28", "cited-by"=>"4", "year"=>"2015", "month"=>"1"}
- {"unique-ip"=>"48", "full-text"=>"46", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2015", "month"=>"2"}
- {"unique-ip"=>"49", "full-text"=>"48", "pdf"=>"27", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
- {"unique-ip"=>"53", "full-text"=>"57", "pdf"=>"33", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
- {"unique-ip"=>"59", "full-text"=>"59", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
- {"unique-ip"=>"60", "full-text"=>"69", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"16", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
- {"unique-ip"=>"53", "full-text"=>"52", "pdf"=>"32", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
- {"unique-ip"=>"81", "full-text"=>"86", "pdf"=>"43", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
- {"unique-ip"=>"125", "full-text"=>"120", "pdf"=>"56", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"12", "cited-by"=>"1", "year"=>"2015", "month"=>"9"}
- {"unique-ip"=>"155", "full-text"=>"165", "pdf"=>"48", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"22", "supp-data"=>"18", "cited-by"=>"2", "year"=>"2015", "month"=>"10"}
- {"unique-ip"=>"121", "full-text"=>"125", "pdf"=>"43", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"4", "cited-by"=>"7", "year"=>"2015", "month"=>"11"}
- {"unique-ip"=>"79", "full-text"=>"92", "pdf"=>"35", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2015", "month"=>"12"}
- {"unique-ip"=>"80", "full-text"=>"68", "pdf"=>"37", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"8", "cited-by"=>"2", "year"=>"2016", "month"=>"1"}
- {"unique-ip"=>"89", "full-text"=>"100", "pdf"=>"34", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"15", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
- {"unique-ip"=>"80", "full-text"=>"82", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"7", "cited-by"=>"1", "year"=>"2016", "month"=>"3"}
- {"unique-ip"=>"52", "full-text"=>"58", "pdf"=>"29", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"17", "cited-by"=>"2", "year"=>"2016", "month"=>"4"}
- {"unique-ip"=>"44", "full-text"=>"52", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
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- {"unique-ip"=>"50", "full-text"=>"60", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"13", "cited-by"=>"1", "year"=>"2016", "month"=>"7"}
- {"unique-ip"=>"44", "full-text"=>"51", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
- {"unique-ip"=>"45", "full-text"=>"52", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"4", "cited-by"=>"4", "year"=>"2016", "month"=>"9"}
- {"unique-ip"=>"60", "full-text"=>"61", "pdf"=>"22", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"19", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
- {"unique-ip"=>"58", "full-text"=>"54", "pdf"=>"22", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"13", "cited-by"=>"6", "year"=>"2016", "month"=>"11"}
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Relative Metric
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