Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness
- Publication Date
- October 16, 2014
- Journal
- PLOS Computational Biology
- Authors
- Srivas Chennu, Paola Finoia, Evelyn Kamau, Judith Allanson, et al
- Volume
- 10
- Issue
- 10
- Pages
- e1003887
- DOI
- https://dx.plos.org/10.1371/journal.pcbi.1003887
- Publisher URL
- http://journals.plos.org/ploscompbiol/article?id=10.1371%2Fjournal.pcbi.1003887
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/25329398
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199497
- Europe PMC
- http://europepmc.org/abstract/MED/25329398
- Web of Science
- 000344547900038
- Scopus
- 84908343115
- Mendeley
- http://www.mendeley.com/research/spectral-signatures-reorganised-brain-networks-disorders-consciousness
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Mendeley | Further Information
{"title"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness", "type"=>"journal", "authors"=>[{"first_name"=>"Srivas", "last_name"=>"Chennu", "scopus_author_id"=>"23975638800"}, {"first_name"=>"Paola", "last_name"=>"Finoia", "scopus_author_id"=>"23091071800"}, {"first_name"=>"Evelyn", "last_name"=>"Kamau", "scopus_author_id"=>"37261390700"}, {"first_name"=>"Judith", "last_name"=>"Allanson", "scopus_author_id"=>"57196970071"}, {"first_name"=>"Guy B.", "last_name"=>"Williams", "scopus_author_id"=>"7406079634"}, {"first_name"=>"Martin M.", "last_name"=>"Monti", "scopus_author_id"=>"18536758300"}, {"first_name"=>"Valdas", "last_name"=>"Noreika", "scopus_author_id"=>"23668497700"}, {"first_name"=>"Aurina", "last_name"=>"Arnatkeviciute", "scopus_author_id"=>"56193785800"}, {"first_name"=>"Andrés", "last_name"=>"Canales-Johnson", "scopus_author_id"=>"50861208900"}, {"first_name"=>"Francisco", "last_name"=>"Olivares", "scopus_author_id"=>"56397890900"}, {"first_name"=>"Daniela", "last_name"=>"Cabezas-Soto", "scopus_author_id"=>"56398433400"}, {"first_name"=>"David K.", "last_name"=>"Menon", "scopus_author_id"=>"7101687199"}, {"first_name"=>"John D.", "last_name"=>"Pickard", "scopus_author_id"=>"7103342237"}, {"first_name"=>"Adrian M.", "last_name"=>"Owen", "scopus_author_id"=>"7202052668"}, {"first_name"=>"Tristan A.", "last_name"=>"Bekinschtein", "scopus_author_id"=>"6506534134"}], "year"=>2014, "source"=>"PLoS Computational Biology", "identifiers"=>{"issn"=>"15537358", "scopus"=>"2-s2.0-84908343115", "pui"=>"600311063", "doi"=>"10.1371/journal.pcbi.1003887", "isbn"=>"10.1371/journal.pcbi.1003887", "sgr"=>"84908343115", "pmid"=>"25329398"}, "id"=>"7d464e07-c855-3e57-ac9a-e5fe6f2574b9", "abstract"=>"Theoretical advances in the science of consciousness have proposed that it is concomitant with balanced cortical integration and differentiation, enabled by efficient networks of information transfer across multiple scales. Here, we apply graph theory to compare key signatures of such networks in high-density electroencephalographic data from 32 patients with chronic disorders of consciousness, against normative data from healthy controls. Based on connectivity within canonical frequency bands, we found that patient networks had reduced local and global efficiency, and fewer hubs in the alpha band. We devised a novel topographical metric, termed modular span, which showed that the alpha network modules in patients were also spatially circumscribed, lacking the structured long-distance interactions commonly observed in the healthy controls. Importantly however, these differences between graph-theoretic metrics were partially reversed in delta and theta band networks, which were also significantly more similar to each other in patients than controls. Going further, we found that metrics of alpha network efficiency also correlated with the degree of behavioural awareness. Intriguingly, some patients in behaviourally unresponsive vegetative states who demonstrated evidence of covert awareness with functional neuroimaging stood out from this trend: they had alpha networks that were remarkably well preserved and similar to those observed in the controls. Taken together, our findings inform current understanding of disorders of consciousness by highlighting the distinctive brain networks that characterise them. In the significant minority of vegetative patients who follow commands in neuroimaging tests, they point to putative network mechanisms that could support cognitive function and consciousness despite profound behavioural impairment.", "link"=>"http://www.mendeley.com/research/spectral-signatures-reorganised-brain-networks-disorders-consciousness", "reader_count"=>242, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>16, "Librarian"=>2, "Researcher"=>44, "Student > Doctoral Student"=>12, "Student > Ph. D. 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Scopus | Further Information
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Article Coverage Curated
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- {"referral"=>"http://www.businessinsider.com.au/amazing-brain-scan-images-reveal-which-coma-patients-are-aware-2014-10", "language"=>"English", "title"=>"These Amazing Brain Scan Images Reveal Which Coma Patients Are Aware", "type"=>"News", "publication"=>"Business Insider", "published_on"=>"2014-10-17T00:00:00.000Z", "link_state"=>"APPROVED", "id"=>27498, "created"=>"2014-10-21T12:40:31.000Z", "crowdsourced"=>false, "article"=>{"id"=>8848, "doi"=>"10.1371/journal.pcbi.1003887", "title"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness", "published_on"=>"2014-10-16T00:00:00.000Z"}}
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Journal Comments | Further Information
- {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/0c315ba0-41a2-4ad8-b0ee-273abcdbdcf3", "title"=>"Very interesting work!", "body"=>"This is a beautiful work. I am not a neuroscientist, so I do not obviously understand many of the points, but upon a quick read I have a few questions.\nFirst, I see that you took pains to ensure that both groups of subjects were \"wakeful\" using I suppose criteria that are considered valid. However, what is the evidence--how confident are we--that the criteria of the 'signals of wakefulness' by which one can characterize that state do indeed hold for the brains of DoC patients? Suppose one were to conduct the same analysis on two groups of healthy volunteers, one 'awake' and another 'asleep'. Might one find similar differences in the connectivity patterns? Would the difference between 'awake' and 'sleeping' brains be as striking? Could there be features of 'sleep' embedded within the DoC brain signals, and perhaps sleep/awake data could potentially disentangle that component?\nSecond, since most (all) definitions of modularity are arbitrary. One generally uses a particular modular decomposition and tries to figure whether that particular decomposition has some functional significance, by looking for statistical enrichment of some attributes (in this case, for e.g., it could have been functional groups of cortical neurons). I don't see a discussion of this issue in the paper. Do the Louvain modules represent functionally significant modules? What if you used a different modular decomposition, such as Markovian clusters or Newman's Q? Do you see significant differences in the 'modular span' with a different modular decomposition compared to Louvain module? \nNonetheless, this is a wonderful paper, and my Facebook friends are all 'liking' it! :-)", "isRemoved"=>false, "created"=>"2014-10-23T02:29:32Z", "lastModified"=>"2014-10-23T02:29:32Z", "creator"=>{"userId"=>"58077"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pcbi.1003887", "state"=>"published", "journals"=>{"PLoSCompBiol"=>{"journalKey"=>"PLoSCompBiol", "eIssn"=>"1553-7358", "title"=>"PLOS Computational Biology"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2014-10-23T21:46:47Z", "replies"=>[{"type"=>"REPLY", "parentID"=>82472, "annotationUri"=>"info:doi/10.1371/reply/acae82c4-163a-4de9-97cc-b09b733832f8", "title"=>"RE: Very interesting work!", "body"=>"Dear Animesh,\n\nThank you for your interest, in addition to the detailed and insightful comments. In response to the key points you raised:\n\n1. Arousal (or vigilance) varies in complex ways in vegetative patients (Landsness et al., 2011; Brain), and indeed, it is often non-trivial to accurately assess true levels of arousal using behaviour. However, as we show using eye-movement activity, there was no evidence that our patients were systematically falling asleep. Hence, though they were unlikely to be asleep throughout, ongoing and rapid fluctuations of arousal in patients during the recording warrants careful interpretation of the limitations and generalisability of these measures.\n\n2. One would certainly expect changes in connectivity during sleep onset and during slow-wave sleep, and there are several studies that have investigated this (Langheim et al., 2011; Tagliazucchi et al., 2013; Ferri et al., 2007, 2008). These lead us to think that the changes in connectivity that distinguish sleep stages from normal wakefulness would be distinct from the changes in connectivity described here between normal wakefulness and disorders of consciousness. Also, the same distinction applies to the comparison of normal wakefulness to propofol sedation, for example.\n\n3. Your suggestion of exploring 'latent' sleep-related connectivity markers in disorders of consciousness patients is certainly very valuable, and something to follow up in the future!\n\n4. The modular decomposition applied here was by definition oblivious to the source of the connectivity data, and hence just relied on strength of connectivity to heuristically identify what it thought to be modules of strongly interconnected nodes. When these modules were overlaid on the head, it ended up highlighting frontoparietal linkages in connectivity within the alpha band in healthy adults (and some patients), and that was certainly interesting. In this sense, not biasing the modularity algorithms by necessitating a brain-inspired functional significance allowed us to use graph theory to make a pure 'topological inference' and later ask if that topological inference actually corresponded to something topographically sensible. Hope that makes sense. We do make this point in the paper, in linking topology to topography via modular span. But your point about identifying modular decompositions that try to maximise the 'statistical enrichment' of some brain-derived attributes is novel, and I think this would yield more illuminating outcomes with fMRI data, where there is spatial detail available to mine.\n\n5. Finally, no we haven't yet tried to use other modular decomposition algorithms; again another methodologically important avenue to explore.\n\nMany thanks again for your comments and suggestions. Glad you liked the paper!", "isRemoved"=>false, "created"=>"2014-10-23T21:46:47Z", "lastModified"=>"2014-10-23T21:46:47Z", "creator"=>{"userId"=>"415501"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pcbi.1003887", "state"=>"published", "journals"=>{"PLoSCompBiol"=>{"journalKey"=>"PLoSCompBiol", "eIssn"=>"1553-7358", "title"=>"PLOS Computational Biology"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2014-10-23T21:46:47Z", "replies"=>[]}]}
- {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/1ee1e38e-af37-4759-b268-a889e860de12", "title"=>"Letter to the Editor", "body"=>"We read with interest the article by Chennu et al (2014) on spectral signatures in persons with disorders of consciousness and believe a few additional comments are worthwhile noting. There have been many recent advances in disorders of consciousness and more focus on the specific behavioral state of the patient regardless of how they may present clinically at the bedside (Gosseries, Zasler, Laureys, 2014). The term ‘functional locked-in syndrome’ has been proposed to describe patients with a dissociation between extreme motor dysfunction and preserved higher cortical functions identified only by functional imaging techniques (Bruno et al., 2011). Moreover, Cruse at al. (2011) demonstrated that it is also possible to detect the hidden awareness of patients in behavioural vegetative state, using an electroencephalographic (EEG) technique. Nevertheless, patients clinically diagnosed in the vegetative state who are able to perform mental imagery tasks (Owen et al., 2006; Monti et al., 2010) are still considered to be in the vegetative state with preserved islands of consciousness, not as having functional locked-in syndrome (Formisano et al., 2011a,b; 2013). Indeed, patients with residual cognitive functions, who are able to perform complex mental imagery tasks or show intentional communication ability with functional neuroimaging techniques, should be diagnosed with functional locked-in syndrome and not vegetative state with hidden consciousness (Formisano et al., 2013). Interestingly, Chennu et al., (2014) applied graph theory by means of high-density electroencephalographic investigation of a series of patients with chronic disorders of consciousness. The metric of alpha network efficiency also correlated with the degree of behavioral awareness. In particular, some patients in behaviorally unresponsive vegetative states who demonstrated evidence of covert awareness with functional neuroimaging, had alpha networks that were preserved and similar to those of the controls. These findings parallel the alpha rhythm commonly found in patients with locked-in syndrome and supports our hypothesis that behaviorally unresponsive patients who follow commands based on functional neuroimaging or neurophysiological tests are not, in fact, in a vegetative/unresponsive wakefulness syndrome (von Wild et al., 2011), but instead in a complete locked-in or functional locked-in syndrome. \n\nDr. Rita Formisano\n\n\nBIBLIOGRAFIA\n\nBruno MA, Vanhaudenhuyse A, Thibaut A, Moonen G, Laureys S. From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: Recent advances in our understanding of disorders of consciousness. Journal of Neurology 2011;258:1373–1384.\n\nChennu S, Finoia P, Kamau E, Allanson J, Williams GB, Monti MM, Noreika V, Arnatkeviciute A, Canales-Johnson A, Olivares F, Cabezas-Soto D, Menon DK, Pickard JD, Owen AM, Bekinschtein TA. Spectral signatures of reorganised brain networks in disorders of consciousness. PLoS Comput Biol. 2014 Oct 16;10(10).\n\nCruse D, Chennu S, Chatelle C, Bekinschtein TA, Fernández-Espejo D, Pickard JD, Laureys S, Owen AM. Bedside detection of awareness in the vegetative state: A cohort study. Lancet 2011;378:2088–2094.\n\nFormisano R, Pistoia F, Sarà M, Disorders of consciousness: A taxonomy to be changed?. Letter to Editor. Brain Injury 2011a, 25(6): 638–639. \n\nFormisano R, D'Ippolito M, Risetti M, Riccio A, Caravasso CF, Catani S, Rizza F, Forcina A, Buzzi MG. Vegetative state, minimally conscious state, akinetic mutism and Parkinsonism as a continuum of recovery from disorders of consciousness: an exploratory and preliminary study. Funct Neurol., 2011b, 26(1):15-24.\n\nFormisano R, D’Ippolito M, Catani S. Functional locked-in syndrome as recovery phase of vegetative state. Letter to the Editor . Brain Injury 2013, Vol. 27, No. 11 , 1332-1332.\n\nMonti MM, Laureys S, Owen AM. The vegetative state. BMJ. 2010;341:3765.\n\nOwen AM, Coleman MR, Boly M, Davis MH, Laureys S, Pickard JD. Detecting awareness in the vegetative state. Science .2006;313:1402—1403\n\nvon Wild K, Laureys ST, Gerstenbrand F, Dolce G, Onose G. The vegetative state--a syndrome in search of a name. J Med Life. 2012 Feb 22;5(1):3-15.\n", "isRemoved"=>false, "created"=>"2015-04-30T13:26:34Z", "lastModified"=>"2015-04-30T13:26:34Z", "creator"=>{"userId"=>"501022"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pcbi.1003887", "state"=>"published", "journals"=>{"PLoSCompBiol"=>{"journalKey"=>"PLoSCompBiol", "eIssn"=>"1553-7358", "title"=>"PLOS Computational Biology"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2015-04-30T13:26:34Z", "replies"=>[]}
- {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/8e55a9a2-337a-4802-ac37-a646ec85bab7", "title"=>"Vegetative State with islands of consciousness or functional Locked-In?", "body"=>"\nWe read with interest the article by Chennu et al (2014) on spectral signatures in persons with disorders of consciousness and believe a few additional comments are worthwhile noting. There have been many recent advances in disorders of consciousness and more focus on the specific behavioral state of the patient regardless of how they may present clinically at the bedside (Gosseries, Zasler, Laureys, 2014). The term ‘functional locked-in syndrome’ has been proposed to describe patients with a dissociation between extreme motor dysfunction and preserved higher cortical functions identified only by functional imaging techniques (Bruno et al., 2011). Moreover, Cruse at al. (2011) demonstrated that it is also possible to detect the hidden awareness of patients in behavioural vegetative state, using an electroencephalographic (EEG) technique. Nevertheless, patients clinically diagnosed in the vegetative state who are able to perform mental imagery tasks (Owen et al., 2006; Monti et al., 2010) are still considered to be in the vegetative state with preserved islands of consciousness, not as having functional locked-in syndrome (Formisano et al., 2011a,b; 2013). Indeed, patients with residual cognitive functions, who are able to perform complex mental imagery tasks or show intentional communication ability with functional neuroimaging techniques, should be diagnosed with functional locked-in syndrome and not vegetative state with hidden consciousness (Formisano et al., 2013). Interestingly, Chennu et al., (2014) applied graph theory by means of high-density electroencephalographic investigation of a series of patients with chronic disorders of consciousness. The metric of alpha network efficiency also correlated with the degree of behavioral awareness. In particular, some patients in behaviorally unresponsive vegetative states who demonstrated evidence of covert awareness with functional neuroimaging, had alpha networks that were preserved and similar to those of the controls. These findings parallel the alpha rhythm commonly found in patients with locked-in syndrome and supports our hypothesis that behaviorally unresponsive patients who follow commands based on functional neuroimaging or neurophysiological tests are not, in fact, in a vegetative/unresponsive wakefulness syndrome (von Wild et al., 2011), but instead in a complete locked-in or functional locked-in syndrome. \n\n\nRita Formisano \nNathan Zasler\n\n\nREFERENCES\n\nBruno MA, Vanhaudenhuyse A, Thibaut A, Moonen G, Laureys S. From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: Recent advances in our understanding of disorders of consciousness. Journal of Neurology 2011;258:1373–1384.\n\nChennu S, Finoia P, Kamau E, Allanson J, Williams GB, Monti MM, Noreika V, Arnatkeviciute A, Canales-Johnson A, Olivares F, Cabezas-Soto D, Menon DK, Pickard JD, Owen AM, Bekinschtein TA. Spectral signatures of reorganised brain networks in disorders of consciousness. PLoS Comput Biol. 2014 Oct 16;10(10).\n\nCruse D, Chennu S, Chatelle C, Bekinschtein TA, Fernández-Espejo D, Pickard JD, Laureys S, Owen AM. Bedside detection of awareness in the vegetative state: A cohort study. Lancet 2011;378:2088–2094.\n\nFormisano R, Pistoia F, Sarà M, Disorders of consciousness: A taxonomy to be changed?. Letter to Editor. Brain Injury 2011a, 25(6): 638–639. \n\nFormisano R, D'Ippolito M, Risetti M, Riccio A, Caravasso CF, Catani S, Rizza F, Forcina A, Buzzi MG. Vegetative state, minimally conscious state, akinetic mutism and Parkinsonism as a continuum of recovery from disorders of consciousness: an exploratory and preliminary study. Funct Neurol., 2011b, 26(1):15-24.\n\nFormisano R, D’Ippolito M, Catani S. Functional locked-in syndrome as recovery phase of vegetative state. Letter to the Editor . Brain Injury 2013, Vol. 27, No. 11 , 1332-1332.\n\nMonti MM, Laureys S, Owen AM. The vegetative state. BMJ. 2010;341:3765.\n\nOwen AM, Coleman MR, Boly M, Davis MH, Laureys S, Pickard JD. Detecting awareness in the vegetative state. Science .2006;313:1402—1403\n\nvon Wild K, Laureys ST, Gerstenbrand F, Dolce G, Onose G. The vegetative state--a syndrome in search of a name. J Med Life. 2012 Feb 22;5(1):3-15.\n", "isRemoved"=>false, "created"=>"2015-05-08T07:27:39Z", "lastModified"=>"2015-05-08T07:27:39Z", "creator"=>{"userId"=>"501022"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pcbi.1003887", "state"=>"published", "journals"=>{"PLoSCompBiol"=>{"journalKey"=>"PLoSCompBiol", "eIssn"=>"1553-7358", "title"=>"PLOS Computational Biology"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2015-05-08T07:27:39Z", "replies"=>[]}
- {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/5c7969eb-aa28-4058-b263-b6699e8c284d", "title"=>"Nice work", "body"=>"Suppose one were to conduct the same analysis on two groups of healthy volunteers, one 'awake' and another 'asleep'. Might one find similar differences in the connectivity patterns? Would the difference between 'awake' and 'sleeping' brains be as striking? Could there be features of 'sleep' embedded within the DoC brain signals, and perhaps sleep/awake data could potentially disentangle that component?\n\n The modular decomposition applied here was by definition oblivious to the source of the connectivity data, and hence just relied on strength of connectivity to heuristically identify what it thought to be modules of strongly interconnected nodes. When these modules were overlaid on the head, it ended up highlighting frontoparietal linkages in connectivity within the alpha band in healthy adults (and some patients), and that was certainly interesting. In this sense, not biasing the modularity algorithms by necessitating a brain-inspired functional significance allowed us to use graph theory to make a pure 'topological inference' and later ask if that topological inference actually corresponded to something topographically sensible. Hope that makes sense.\nThanks,\nhttp://www.fixithere.net/vodafone-customer-service/", "isRemoved"=>false, "created"=>"2016-02-08T13:05:51Z", "lastModified"=>"2016-02-08T13:05:51Z", "creator"=>{"userId"=>"500041"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pcbi.1003887", "state"=>"published", "journals"=>{"PLoSCompBiol"=>{"journalKey"=>"PLoSCompBiol", "eIssn"=>"1553-7358", "title"=>"PLOS Computational Biology"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2016-02-08T13:05:51Z", "replies"=>[]}
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- {"id"=>"522861939374837760", "text"=>"Mi hermano @TrikBek es tan grosso que trabaja en algoritmos para detec conciencia en pacientes con daño cerebral. http://t.co/p0OizfvuGj", "created_at"=>"2014-10-16T21:29:35Z", "user"=>"soyingridbeck", "user_name"=>"Ingrid Beck", "user_profile_image"=>"http://pbs.twimg.com/profile_images/498652069507891200/6-UsxyuY_normal.jpeg"}
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- {"id"=>"522878572457783297", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/YoBI8FN7Y0", "created_at"=>"2014-10-16T22:35:40Z", "user"=>"cjwijtmans", "user_name"=>"Christ-Jan Wijtmans", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_0_normal.png"}
- {"id"=>"522880134458515457", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:41:53Z", "user"=>"EnricoCoiera", "user_name"=>"Enrico Coiera", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1676377810/Coiera_inside_normal.jpg"}
- {"id"=>"522880240255635457", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:42:18Z", "user"=>"montsep", "user_name"=>"montsep", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1228881414/dibujo1_normal.jpg"}
- {"id"=>"522880401518252032", "text"=>"#bioinformatics identifies the networks of consciousness http://t.co/KaFtzP477h", "created_at"=>"2014-10-16T22:42:57Z", "user"=>"LussierY", "user_name"=>"Prof. Yves Lussier", "user_profile_image"=>"http://pbs.twimg.com/profile_images/494365134945398786/kn6gdHKB_normal.jpeg"}
- {"id"=>"522881223270883328", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:46:12Z", "user"=>"pilarcubas", "user_name"=>"pilarcubas", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2378727879/6oju28xw43gi5olqfqe7_normal.jpeg"}
- {"id"=>"522881422227283969", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/dPgWEgqK0y", "created_at"=>"2014-10-16T22:47:00Z", "user"=>"MarikaTaddia", "user_name"=>"Marika Taddia", "user_profile_image"=>"http://pbs.twimg.com/profile_images/469055248854577152/RSqxVjYa_normal.png"}
- {"id"=>"522881569392844800", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:47:35Z", "user"=>"DrRBGale", "user_name"=>"Dr RB Gale", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3184845109/e07e7497dad711be3de840831d039bb5_normal.jpeg"}
- {"id"=>"522881779972440064", "text"=>"RT @PLOSNeuro: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/VtIbYUAqoW from @PLOSCompBiol", "created_at"=>"2014-10-16T22:48:25Z", "user"=>"Paleo_Bonegirl", "user_name"=>"Paleo Bonegirl", "user_profile_image"=>"http://pbs.twimg.com/profile_images/464571024462213120/no390Yps_normal.jpeg"}
- {"id"=>"522882575916740609", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:51:35Z", "user"=>"rechelon", "user_name"=>"William Gillis", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2911922320/db5742818f78da715c40ec5158d58fee_normal.jpeg"}
- {"id"=>"522883248020414465", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:54:15Z", "user"=>"puellavulnerata", "user_name"=>"Andreⓐ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1239788528/andrea_profile_normal.png"}
- {"id"=>"522883451410595842", "text"=>"Worst hair evar RT @PLOS What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/DILoZ0Em45 http://t.co/cGtR1zk8Bz", "created_at"=>"2014-10-16T22:55:04Z", "user"=>"bungalowranch", "user_name"=>"Cora Potter", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2774420626/94f84f498c80c9fcc902d3acc776aa25_normal.jpeg"}
- {"id"=>"522884563442597888", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:59:29Z", "user"=>"Aisha12895124", "user_name"=>"Aisha", "user_profile_image"=>"http://pbs.twimg.com/profile_images/486493971594489856/ayrqxkjE_normal.jpeg"}
- {"id"=>"522884567607160835", "text"=>"意識障害の患者でα波のハブが少なく、ローカル・グローバルな効率性が低下し、長距離結合が弱まっているが、δ波やθ波では普通のまま。植物状態でも意識があればα波のネットワークは健康人と変わらない。Spectral Signatures …http://t.co/RF0Do3WX8E", "created_at"=>"2014-10-16T22:59:30Z", "user"=>"uranus_2", "user_name"=>"マーキュリー2世", "user_profile_image"=>"http://pbs.twimg.com/profile_images/520761051646676992/x2e9wBQE_normal.png"}
- {"id"=>"522884638721589248", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T22:59:47Z", "user"=>"virtadpt", "user_name"=>"The Doctor", "user_profile_image"=>"http://pbs.twimg.com/profile_images/506502683608350720/TtDl6K1N_normal.jpeg"}
- {"id"=>"522887048135340033", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/O6eHlWJBqY via @feedly", "created_at"=>"2014-10-16T23:09:21Z", "user"=>"lshlj", "user_name"=>"SangHoon Lee", "user_profile_image"=>"http://pbs.twimg.com/profile_images/521109856384593920/bMjBFXTr_normal.jpeg"}
- {"id"=>"522889436212641794", "text"=>"Fascinating. “@PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/sK6FBlj0fM http://t.co/RHLemp8h3o”", "created_at"=>"2014-10-16T23:18:51Z", "user"=>"451wendy", "user_name"=>"Wendy Nather", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2856863492/b626dd8e1c73f51cda522ee02003e5aa_normal.jpeg"}
- {"id"=>"522891759148208128", "text"=>"Healthy brain awareness networks are impaired in the brains of vegetative patients http://t.co/6acPu5GZ6Y http://t.co/3a6S25cZju", "created_at"=>"2014-10-16T23:28:04Z", "user"=>"AusSMC", "user_name"=>"Au Science Media Ctr", "user_profile_image"=>"http://pbs.twimg.com/profile_images/488888199431741440/yPdP6Z2j_normal.jpeg"}
- {"id"=>"522892272543625217", "text"=>"RT @AusSMC: Healthy brain awareness networks are impaired in the brains of vegetative patients http://t.co/6acPu5GZ6Y http://t.co/3a6S25cZju", "created_at"=>"2014-10-16T23:30:07Z", "user"=>"VicBioImaging", "user_name"=>"VBIC", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2329972750/eoi5fxez9k5muwwyf9d6_normal.png"}
- {"id"=>"522897571287543808", "text"=>"RT @uranus_2: 意識障害の患者でα波のハブが少なく、ローカル・グローバルな効率性が低下し、長距離結合が弱まっているが、δ波やθ波では普通のまま。植物状態でも意識があればα波のネットワークは健康人と変わらない。Spectral Signatures …http://…", "created_at"=>"2014-10-16T23:51:10Z", "user"=>"FUJIKIDaisuke", "user_name"=>"ふじきだいすけ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3107701402/14564fa71237424a1e0d6b8d61a98a82_normal.gif"}
- {"id"=>"522898280448282624", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-16T23:53:59Z", "user"=>"alizardx", "user_name"=>"A.Lizard", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1228901030/alizard-150x150_normal.jpg"}
- {"id"=>"522898805545779201", "text"=>"Abbiamo grafi nel cervello http://t.co/Fl3wJYqUbO", "created_at"=>"2014-10-16T23:56:04Z", "user"=>"sergio_cima", "user_name"=>"Sergio Cima", "user_profile_image"=>"http://pbs.twimg.com/profile_images/436628174906986496/4OaEzGMU_normal.png"}
- {"id"=>"522909665945210880", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T00:39:14Z", "user"=>"Thelper666", "user_name"=>"helper T cell 666", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3325992063/d32621dca0b048b6b17817456597e670_normal.jpeg"}
- {"id"=>"522920771149000704", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T01:23:21Z", "user"=>"RameshUCMerced", "user_name"=>"Ramesh UCMerced", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000063240671/de5392bd2c8c1da49b9d809e8dadd1a7_normal.jpeg"}
- {"id"=>"522927879928426497", "text"=>"Very interesting article: \"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness\"\nhttp://t.co/cbzlEXjumz", "created_at"=>"2014-10-17T01:51:36Z", "user"=>"raziqnazqua", "user_name"=>"Raziq Nazqua", "user_profile_image"=>"http://pbs.twimg.com/profile_images/473953005/c1_normal.jpg"}
- {"id"=>"522938123504730113", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness. http://t.co/u0YB9CQJzL", "created_at"=>"2014-10-17T02:32:19Z", "user"=>"TakeshiHase", "user_name"=>"長谷武志", "user_profile_image"=>"http://pbs.twimg.com/profile_images/482095118271266817/cNdb_6wa_normal.jpeg"}
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- {"id"=>"522973777097793536", "text"=>"RT @Comadork: Reorganised Brain Networks in Disorders of Consciousness - published today http://t.co/xXWwDDyaaz", "created_at"=>"2014-10-17T04:53:59Z", "user"=>"PaulEDux", "user_name"=>"Paul E. Dux", "user_profile_image"=>"http://pbs.twimg.com/profile_images/469292063352037377/amFXrgaT_normal.jpeg"}
- {"id"=>"522978451859312642", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/5e7yLjyFlq", "created_at"=>"2014-10-17T05:12:34Z", "user"=>"byzant69", "user_name"=>"Sergii Tukaiev", "user_profile_image"=>"http://pbs.twimg.com/profile_images/490590048329289728/9q4cT_dI_normal.jpeg"}
- {"id"=>"522985334414385152", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness @TrikBek @Comadork et al http://t.co/VkdA6Sxzkd #GraphTheory", "created_at"=>"2014-10-17T05:39:54Z", "user"=>"sarcastic_f", "user_name"=>"sarcastic_f", "user_profile_image"=>"http://pbs.twimg.com/profile_images/275152451/Exploded_Brain_normal.jpg"}
- {"id"=>"522992425015730176", "text"=>"RT @sarcastic_f: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness @TrikBek @Comadork et al http://t.co/VkdA6…", "created_at"=>"2014-10-17T06:08:05Z", "user"=>"IgorCarron", "user_name"=>"Igor Carron", "user_profile_image"=>"http://pbs.twimg.com/profile_images/52435623/igor_normal.JPG"}
- {"id"=>"523007156417994753", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T07:06:37Z", "user"=>"Jayarava", "user_name"=>"Jayarava | जयरव", "user_profile_image"=>"http://pbs.twimg.com/profile_images/511950748796473344/oPxKObWO_normal.jpeg"}
- {"id"=>"523007833848041473", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/HYrBvjbO11", "created_at"=>"2014-10-17T07:09:19Z", "user"=>"Jayarava", "user_name"=>"Jayarava | जयरव", "user_profile_image"=>"http://pbs.twimg.com/profile_images/511950748796473344/oPxKObWO_normal.jpeg"}
- {"id"=>"523008287416254464", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T07:11:07Z", "user"=>"ScienceAndWine", "user_name"=>"Michael Mohammadi", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3411213936/ab1cb3524f93a7de1d1b309f92e086ca_normal.jpeg"}
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- {"id"=>"523049308950888449", "text"=>"BBC News - Vegetative patients show glimmers of consciousness http://t.co/VeUVUVcwnL (paper at @PLOSCompBiol http://t.co/o7zIJ6cmtl)", "created_at"=>"2014-10-17T09:54:07Z", "user"=>"McDawg", "user_name"=>"Graham Steel", "user_profile_image"=>"http://pbs.twimg.com/profile_images/512880144004808704/bMcHoEpu_normal.png"}
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- {"id"=>"523051083757678593", "text"=>"RT @McDawg: BBC News - Vegetative patients show glimmers of consciousness http://t.co/VeUVUVcwnL (paper at @PLOSCompBiol http://t.co/o7zIJ6…", "created_at"=>"2014-10-17T10:01:10Z", "user"=>"PLOSCompBiol", "user_name"=>"PLOS Comp Biol", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2435436417/hg8nh61i55aibgx0hcvp_normal.jpeg"}
- {"id"=>"523052151841763328", "text"=>"Scientists have found “hidden” brain activity that can indicate if a vegetative patient is aware http://t.co/jJcMhoUNu7", "created_at"=>"2014-10-17T10:05:25Z", "user"=>"Science_Reddit", "user_name"=>"Reddit Science", "user_profile_image"=>"http://pbs.twimg.com/profile_images/480229204919742465/DHLw_QAc_normal.png"}
- {"id"=>"523052587260854272", "text"=>"RT @McDawg: BBC News - Vegetative patients show glimmers of consciousness http://t.co/VeUVUVcwnL (paper at @PLOSCompBiol http://t.co/o7zIJ6…", "created_at"=>"2014-10-17T10:07:09Z", "user"=>"gladrandomgraph", "user_name"=>"Dan Søndergaard", "user_profile_image"=>"http://pbs.twimg.com/profile_images/504988846275035138/DHwJ4ayp_normal.jpeg"}
- {"id"=>"523052737110757376", "text"=>"RT @McDawg: BBC News - Vegetative patients show glimmers of consciousness http://t.co/VeUVUVcwnL (paper at @PLOSCompBiol http://t.co/o7zIJ6…", "created_at"=>"2014-10-17T10:07:45Z", "user"=>"RTFMCelia", "user_name"=>"celia", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1795863835/jonhyRamone_normal.jpg"}
- {"id"=>"523052922926800896", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T10:08:29Z", "user"=>"Betasciencepres", "user_name"=>"Betasciencepress", "user_profile_image"=>"http://pbs.twimg.com/profile_images/483021429265293314/PNkd8QWX_normal.png"}
- {"id"=>"523062918900764672", "text"=>"New study shows consciousness in vegetative patients http://t.co/vEkHQEXVod #crnurse #inthenews #health", "created_at"=>"2014-10-17T10:48:12Z", "user"=>"NIHRCRN_nwcoast", "user_name"=>"NIHR CRN NW Coast", "user_profile_image"=>"http://pbs.twimg.com/profile_images/453201393138946049/Ejgd84oG_normal.jpeg"}
- {"id"=>"523066975724240896", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-17T11:04:19Z", "user"=>"cunnusdiaboli", "user_name"=>"Synaptic Simulator ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/507259065139863552/gIx6QjpT_normal.jpeg"}
- {"id"=>"523075895020355584", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/QXZapJvGRo", "created_at"=>"2014-10-17T11:39:46Z", "user"=>"ar0mcintosh", "user_name"=>"Randy McIntosh", "user_profile_image"=>"http://pbs.twimg.com/profile_images/423861064153825280/mOKY26x9_normal.jpeg"}
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- {"id"=>"523089790175301632", "text"=>"RT @ar0mcintosh: #PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/QXZapJvGRo", "created_at"=>"2014-10-17T12:34:59Z", "user"=>"daspainbrain", "user_name"=>"Dave Seminowicz", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000031597039/4b2eb3c09dd94538d7616831a0469861_normal.jpeg"}
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- {"id"=>"523112684662054912", "text"=>"Signatures of Consciousness http://t.co/Cl4BNAdWZF", "created_at"=>"2014-10-17T14:05:57Z", "user"=>"marcoiacoboni", "user_name"=>"marco iacoboni", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1670919360/picture_normal.jpg"}
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- {"id"=>"523162014277844993", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/1uXQ0wq84s", "created_at"=>"2014-10-17T17:21:58Z", "user"=>"sh33pbrain", "user_name"=>"sh33pbrain", "user_profile_image"=>"http://pbs.twimg.com/profile_images/441462332141490176/XtHWKLmy_normal.jpeg"}
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- {"id"=>"523195748788490240", "text"=>"Trazas de actividad cerebral en personas en coma http://t.co/0n9EZCv45c", "created_at"=>"2014-10-17T19:36:01Z", "user"=>"biblum", "user_name"=>"Biblum", "user_profile_image"=>"http://pbs.twimg.com/profile_images/799155331/AAB_normal.JPG"}
- {"id"=>"523199928961474560", "text"=>"Graph theoretic analysis of spectral signatures of brains. http://t.co/V6rbHyjBh5", "created_at"=>"2014-10-17T19:52:38Z", "user"=>"meangrape", "user_name"=>"Jay.", "user_profile_image"=>"http://pbs.twimg.com/profile_images/453022580291534848/1GwfOoTW_normal.jpeg"}
- {"id"=>"523230802306682880", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/ELO6Je1aTk", "created_at"=>"2014-10-17T21:55:19Z", "user"=>"ruthstarkman", "user_name"=>"Ruth Starkman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/464799271359754241/CKbMyI67_normal.jpeg"}
- {"id"=>"523240640742563840", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/9aURp1g1CX", "created_at"=>"2014-10-17T22:34:24Z", "user"=>"bf4tbrainy", "user_name"=>"Rebecca McMillan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515310491766251520/hBbDyoij_normal.jpeg"}
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- {"id"=>"523299576573624320", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-18T02:28:36Z", "user"=>"THebertMcGill", "user_name"=>"Terry Hébert", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3692558110/d2221dcaa41123dc08b3717e79d90d48_normal.jpeg"}
- {"id"=>"523387684216004608", "text"=>"Consciousness as a measure of balanced information transfers. http://t.co/G1vWHxWacO", "created_at"=>"2014-10-18T08:18:42Z", "user"=>"Grady_Booch", "user_name"=>"Grady Booch", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3477916355/d16aeab64093934dfa257e1954da496a_normal.jpeg"}
- {"id"=>"523405040477032449", "text"=>"RT @Grady_Booch: Consciousness as a measure of balanced information transfers. http://t.co/G1vWHxWacO", "created_at"=>"2014-10-18T09:27:40Z", "user"=>"_evetro_", "user_name"=>"Dmitri Kuvshinov", "user_profile_image"=>"http://pbs.twimg.com/profile_images/848864360/MilkyWaySmall_normal.jpg"}
- {"id"=>"523411640797376512", "text"=>"RT @PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/XrG1qsS7L4 http://t.co/VnU0uusiEx", "created_at"=>"2014-10-18T09:53:54Z", "user"=>"ilkeryoldas", "user_name"=>"ilker yoldas", "user_profile_image"=>"http://pbs.twimg.com/profile_images/413693425859321856/cAJUt556_normal.png"}
- {"id"=>"523447772796964864", "text"=>"RT @Grady_Booch: Consciousness as a measure of balanced information transfers. http://t.co/G1vWHxWacO", "created_at"=>"2014-10-18T12:17:28Z", "user"=>"nkuriakos", "user_name"=>"nkuriakos", "user_profile_image"=>"http://pbs.twimg.com/profile_images/459442017123053568/W--c5N9C_normal.jpeg"}
- {"id"=>"523722724800466944", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness : PloS Computational Biology http://t.co/kYgzECQp74", "created_at"=>"2014-10-19T06:30:02Z", "user"=>"BrainCosmos", "user_name"=>"Brain", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2265616844/u1xz0rtlbmgl1bthyaxi_normal.gif"}
- {"id"=>"523723635446800384", "text"=>"RT @BrainCosmos: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness : PloS Computational Biology http://t.co/k…", "created_at"=>"2014-10-19T06:33:39Z", "user"=>"MaverickIndeed", "user_name"=>"CBGIIIMD", "user_profile_image"=>"http://pbs.twimg.com/profile_images/521498553005641728/docqAs7-_normal.jpeg"}
- {"id"=>"523757342408445953", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/tA04rmYGWF", "created_at"=>"2014-10-19T08:47:36Z", "user"=>"TauberLab", "user_name"=>"Tauber Lab", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3676197892/d1b1f6a6faa1904f9f3e754d9242116d_normal.jpeg"}
- {"id"=>"523799238526775296", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/t6xHiiWMAn", "created_at"=>"2014-10-19T11:34:04Z", "user"=>"jelena_mrdalj", "user_name"=>"Jelena Mrdalj", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1196406032/jelena_1_normal.jpg"}
- {"id"=>"523909914524401664", "text"=>"RT @BrainCosmos: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness : PloS Computational Biology http://t.co/k…", "created_at"=>"2014-10-19T18:53:52Z", "user"=>"Neuronet64", "user_name"=>"Lauren Thompson", "user_profile_image"=>"http://pbs.twimg.com/profile_images/488497413863530496/p9T73Wd8_normal.jpeg"}
- {"id"=>"523948045503696896", "text"=>"From @PLOSCompBio - Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/9p7llTfgxf", "created_at"=>"2014-10-19T21:25:23Z", "user"=>"GinnyBarbour", "user_name"=>"Ginny Barbour", "user_profile_image"=>"http://pbs.twimg.com/profile_images/485551004138471425/cAjg-V6T_normal.jpeg"}
- {"id"=>"523990341540937729", "text"=>"RT @451wendy: Fascinating. “@PLOS: What are the neural signatures of consciousness? New in @PLOSCompbiol http://t.co/sK6FBlj0fM http://t.co…", "created_at"=>"2014-10-20T00:13:27Z", "user"=>"vusecurity", "user_name"=>"VU Security", "user_profile_image"=>"http://pbs.twimg.com/profile_images/487352026171707392/SlFgFRhy_normal.jpeg"}
- {"id"=>"523992504949932032", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/Nn2maQQHvM", "created_at"=>"2014-10-20T00:22:03Z", "user"=>"rayhv11", "user_name"=>"Raymond Vazquez, PhD", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2379691498/98kfxaoresfcv6tfzjqu_normal.jpeg"}
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- {"id"=>"524044158361931776", "text"=>"http://t.co/SeGW5zwbxs \nconsciousness signature ..", "created_at"=>"2014-10-20T03:47:18Z", "user"=>"khalidsadek13", "user_name"=>"khalid sadek", "user_profile_image"=>"http://pbs.twimg.com/profile_images/523447820557115392/vCpW22in_normal.jpeg"}
- {"id"=>"524178853129113600", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness ia @PLOSCompbiol http://t.co/gPqRZuSGjl", "created_at"=>"2014-10-20T12:42:32Z", "user"=>"MU_Peter", "user_name"=>"MU - Peter Shimon", "user_profile_image"=>"http://pbs.twimg.com/profile_images/509905532262432768/GfAVdH___normal.jpeg"}
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- {"id"=>"524487667761676288", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/hXaStCuEUs", "created_at"=>"2014-10-21T09:09:39Z", "user"=>"IJRoIJals", "user_name"=>"I Jey ~Ivan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/519092046389186561/I1ytzcDZ_normal.jpeg"}
- {"id"=>"524660264533110785", "text"=>"#SCIENCE Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/x91ar21P63", "created_at"=>"2014-10-21T20:35:29Z", "user"=>"squeevey", "user_name"=>"Michale", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1789080573/Die_Mensch-Maschine_normal.jpg"}
- {"id"=>"524870556341256192", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/yGsIrbRELL", "created_at"=>"2014-10-22T10:31:06Z", "user"=>"lindenitzan", "user_name"=>"Dr Nitzan Lindenberg", "user_profile_image"=>"http://pbs.twimg.com/profile_images/447111006326894593/vpfT5u6Y_normal.jpeg"}
- {"id"=>"524904802590130176", "text"=>"We may be able to detect if vegatative patients are conscious using EEG and graph theory -- @PLOSCompBiol http://t.co/bZiULMODDN", "created_at"=>"2014-10-22T12:47:11Z", "user"=>"Neuroamer", "user_name"=>"Ben Kuebrich", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2235161007/Neuroamer-small_normal.jpg"}
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- {"id"=>"526872051068715010", "text"=>"http://t.co/aOuQcutGdm http://t.co/SHP8MSI7hA", "created_at"=>"2014-10-27T23:04:20Z", "user"=>"ATventurExist", "user_name"=>"ATventure", "user_profile_image"=>"http://pbs.twimg.com/profile_images/484714363702349824/NAHsC0EO_normal.jpeg"}
- {"id"=>"526975311968083968", "text"=>"Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness\n\nhttp://t.co/KkdlQziv8j", "created_at"=>"2014-10-28T05:54:39Z", "user"=>"sryhary", "user_name"=>"Sridhar ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515654069726085120/nTc42wbu_normal.jpeg"}
- {"id"=>"527427231568896002", "text"=>"PLOS Computational Biology: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/fGiZYFPSRC", "created_at"=>"2014-10-29T11:50:25Z", "user"=>"thisismikedunn", "user_name"=>"Mike Dunn", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3150281798/d1e2ee1efc83ef69dd1f9f4d2b0ecd80_normal.jpeg"}
- {"id"=>"527513737670844417", "text"=>"@Neuro_Skeptic @PLOSNeuro \nNeuroskeptic goes in-depth with Srivas Chennu: http://t.co/ZcgXvRpEQ5 Research article: http://t.co/LykuQPVzVQ", "created_at"=>"2014-10-29T17:34:10Z", "user"=>"PLOSCompBiol", "user_name"=>"PLOS Comp Biol", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2435436417/hg8nh61i55aibgx0hcvp_normal.jpeg"}
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- {"id"=>"527972308250402816", "text"=>"#PLOSCompBio: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/hDLE5ypvCt", "created_at"=>"2014-10-30T23:56:22Z", "user"=>"MahadevanVivek", "user_name"=>"Vivek Mahadevan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/478695583104765952/Euu9nbiQ_normal.jpeg"}
- {"id"=>"528144695822532609", "text"=>"#Brain injury #patients can sometimes demonstrate more #awareness of surroundings than previously thought http://t.co/ipg2hEj6vo", "created_at"=>"2014-10-31T11:21:22Z", "user"=>"MedicalClerical", "user_name"=>"Medical Clerical", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515103969937354752/Ht_REG31_normal.jpeg"}
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- {"id"=>"529222047432736768", "text"=>"More - Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness #Science \nhttp://t.co/FsmRdc8MiC", "created_at"=>"2014-11-03T10:42:23Z", "user"=>"AmyAmylou1993", "user_name"=>"Amy Carparelli ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/524260497198047232/Pwke-bSN_normal.jpeg"}
- {"id"=>"533758237120954368", "text"=>"Komaya giren bazı hastaların aslında bilinçli olduğunu kanıtladılar...vücuduna hapsolmuş bilincin fotoğrafı çekildi\nhttp://t.co/DRbEMlWf1A", "created_at"=>"2014-11-15T23:07:35Z", "user"=>"bgurcihan", "user_name"=>"Behiç Gürcihan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000491677203/3169fae97fd4db7f9819bf3081451513_normal.jpeg"}
- {"id"=>"533759167920898048", "text"=>"RT @bgurcihan: Komaya giren bazı hastaların aslında bilinçli olduğunu kanıtladılar...vücuduna hapsolmuş bilincin fotoğrafı çekildi\nhttp://t…", "created_at"=>"2014-11-15T23:11:17Z", "user"=>"zen1su", "user_name"=>"fermai", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000346792788/ebfb848aba87f4300b40fb9ef21392d2_normal.jpeg"}
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- {"id"=>"538281777106669568", "text"=>"RT @IJRoIJals: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/hXaStCuEUs", "created_at"=>"2014-11-28T10:42:31Z", "user"=>"it03b", "user_name"=>"takashi", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515456594016882688/ptwishcH_normal.jpeg"}
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- {"id"=>"549983341177761792", "text"=>"Chennu et al feature on @WIRED's top science visualizations of the year! http://t.co/NpYmnCR8QF\nRead the paper: http://t.co/mLlbERlJ6Z", "created_at"=>"2014-12-30T17:40:21Z", "user"=>"PLOSCompBiol", "user_name"=>"PLOS Comp Biol", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2435436417/hg8nh61i55aibgx0hcvp_normal.jpeg"}
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- {"id"=>"610756805472325634", "text"=>"RT @IJRoIJals: Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness http://t.co/hXaStCuEUs", "created_at"=>"2015-06-16T10:32:24Z", "user"=>"rajivmohare", "user_name"=>"Rajiv Mohare", "user_profile_image"=>"http://pbs.twimg.com/profile_images/441393409018712064/kyXfpYG-_normal.jpeg"}
- {"id"=>"651683237232812032", "text"=>"@ladamic @SNAcourse Some reading for your next @coursera SNA class: networks of brain activity in consciousness http://t.co/6NsK4VXSrS", "created_at"=>"2015-10-07T08:59:26Z", "user"=>"stevensenior", "user_name"=>"Steven Senior", "user_profile_image"=>"http://pbs.twimg.com/profile_images/648194599006117890/IIaOblLM_normal.jpg"}
- {"id"=>"686176938499543040", "text"=>"前者の元論文がhttps://t.co/LfVPyoOszSで、後者の元論文がhttps://t.co/3PPqBOrrDK スリバス・チェヌ氏はクルーズ氏のコレhttps://t.co/5k1ZVuOxpWの共著者。無論かぶってるからダメという話ではないが・・・。", "created_at"=>"2016-01-10T13:25:05Z", "user"=>"berutei", "user_name"=>"ベル邸", "user_profile_image"=>"http://pbs.twimg.com/profile_images/505518589961465856/lc-UL9sX_normal.png"}
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