Pro-Aging Effects of Glucose Signaling through a G Protein-Coupled Glucose Receptor in Fission Yeast
- Publication Date
- March 06, 2009
- Journal
- PLOS Genetics
- Authors
- Antoine E. Roux, Alexandre Leroux, Manal A. Alaamery, Charles S. Hoffman, et al
- Volume
- 5
- Issue
- 3
- Pages
- e1000408
- DOI
- https://dx.plos.org/10.1371/journal.pgen.1000408
- Publisher URL
- http://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1000408
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/19266076
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646135
- Europe PMC
- http://europepmc.org/abstract/MED/19266076
- Web of Science
- 000266320100014
- Scopus
- 62149091061
- Mendeley
- http://www.mendeley.com/research/proaging-effects-glucose-signaling-through-g-proteincoupled-glucose-receptor-fission-yeast
Loading … 

Events
Loading … 

Mendeley | Further Information
{"title"=>"Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast", "type"=>"journal", "authors"=>[{"first_name"=>"Antoine E.", "last_name"=>"Roux", "scopus_author_id"=>"57197412470"}, {"first_name"=>"Alexandre", "last_name"=>"Leroux", "scopus_author_id"=>"25923428900"}, {"first_name"=>"Manal A.", "last_name"=>"Alaamery", "scopus_author_id"=>"24400909800"}, {"first_name"=>"Charles S.", "last_name"=>"Hoffman", "scopus_author_id"=>"35546828200"}, {"first_name"=>"Pascal", "last_name"=>"Chartrand", "scopus_author_id"=>"7005909097"}, {"first_name"=>"Gerardo", "last_name"=>"Ferbeyre", "scopus_author_id"=>"6701806770"}, {"first_name"=>"Luis A.", "last_name"=>"Rokeach", "scopus_author_id"=>"7004061863"}], "year"=>2009, "source"=>"PLoS Genetics", "identifiers"=>{"pmid"=>"19266076", "sgr"=>"62149091061", "doi"=>"10.1371/journal.pgen.1000408", "scopus"=>"2-s2.0-62149091061", "pui"=>"354404890", "isbn"=>"1553-7404 (Electronic)", "issn"=>"15537390"}, "id"=>"8e9f8a60-f2c2-3f62-8d9e-bdf487b80f91", "abstract"=>"Glucose is the preferred carbon and energy source in prokaryotes, unicellular eukaryotes, and metazoans. However, excess of glucose has been associated with several diseases, including diabetes and the less understood process of aging. On the contrary, limiting glucose (i.e., calorie restriction) slows aging and age-related diseases in most species. Understanding the mechanism by which glucose limits life span is therefore important for any attempt to control aging and age-related diseases. Here, we use the yeast Schizosaccharomyces pombe as a model to study the regulation of chronological life span by glucose. Growth of S. pombe at a reduced concentration of glucose increased life span and oxidative stress resistance as reported before for many other organisms. Surprisingly, loss of the Git3 glucose receptor, a G protein-coupled receptor, also increased life span in conditions where glucose consumption was not affected. These results suggest a role for glucose-signaling pathways in life span regulation. In agreement, constitutive activation of the Galpha subunit acting downstream of Git3 accelerated aging in S. pombe and inhibited the effects of calorie restriction. A similar pro-aging effect of glucose was documented in mutants of hexokinase, which cannot metabolize glucose and, therefore, are exposed to constitutive glucose signaling. The pro-aging effect of glucose signaling on life span correlated with an increase in reactive oxygen species and a decrease in oxidative stress resistance and respiration rate. Likewise, the anti-aging effect of both calorie restriction and the Deltagit3 mutation was accompanied by increased respiration and lower reactive oxygen species production. Altogether, our data suggest an important role for glucose signaling through the Git3/PKA pathway to regulate S. pombe life span.", "link"=>"http://www.mendeley.com/research/proaging-effects-glucose-signaling-through-g-proteincoupled-glucose-receptor-fission-yeast", "reader_count"=>87, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>4, "Researcher"=>20, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>27, "Student > Postgraduate"=>6, "Student > Master"=>8, "Student > Bachelor"=>12, "Professor"=>6}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>4, "Researcher"=>20, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>27, "Student > Postgraduate"=>6, "Student > Master"=>8, "Student > Bachelor"=>12, "Professor"=>6}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>13, "Agricultural and Biological Sciences"=>69, "Medicine and Dentistry"=>1, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>69}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>13}, "Unspecified"=>{"Unspecified"=>2}, "Environmental Science"=>{"Environmental Science"=>1}}, "reader_count_by_country"=>{"Sweden"=>1, "United States"=>4, "United Kingdom"=>1, "Mexico"=>1, "Australia"=>1, "Switzerland"=>1, "Germany"=>1, "India"=>1}, "group_count"=>2}CrossRef
- http://doi.org/10.1091/mbc.E19-03-0172
- http://doi.org/10.1007/s10528-011-9477-x
- http://doi.org/10.1016/j.exger.2010.03.014
- http://doi.org/10.1271/bbb.130223
- http://doi.org/10.1371/journal.pone.0121877
- http://doi.org/10.1093/femsle/fnw257
- http://doi.org/10.1002/jcp.28386
- http://doi.org/10.1038/nature08981
- http://doi.org/10.1007/s00018-016-2432-6
- http://doi.org/10.1371/journal.pone.0121059
- http://doi.org/10.1038/emboj.2009.407
- http://doi.org/10.5812/jjm.8(6)2015.16851
- http://doi.org/10.1093/femsyr/fox066
- http://doi.org/10.1016/j.freeradbiomed.2011.05.010
- http://doi.org/10.5812/jjm.8(5)2015.16851
- http://doi.org/10.1111/j.1567-1364.2012.00826.x
- http://doi.org/10.2203/dose-response.13-035.Ristow
- http://doi.org/10.1111/1567-1364.12113
- http://doi.org/10.1093/femsyr/fow061
- http://doi.org/10.5604/01.3001.0010.4877
- http://doi.org/10.1111/acel.12277
- http://doi.org/10.1016/j.carres.2011.03.005
- http://doi.org/10.1002/jcp.25824
- http://doi.org/10.1128/AEM.00515-16
- http://doi.org/10.1002/cbin.10722
- http://doi.org/10.1111/j.1749-6632.2010.05198.x
- http://doi.org/10.1002/cbin.10556
- http://doi.org/10.3109/10409238.2015.1103205
- http://doi.org/10.1111/gtc.12604
- http://doi.org/10.1111/j.1742-4658.2011.08050.x
- http://doi.org/10.1111/febs.15052
- http://doi.org/10.1016/j.mito.2015.04.003
- http://doi.org/10.1007/s00438-013-0748-6
- http://doi.org/10.1093/gerona/glp152
- http://doi.org/10.1139/Y10-001
- http://doi.org/10.1016/j.mimet.2016.05.023
- http://doi.org/10.1534/g3.114.014415
- http://doi.org/10.1002/yea.1626
- http://doi.org/10.1111/acel.12080
Europe PMC Database Citations | Further Information
{"UNIPROT"=>4}Scopus | Further Information
{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/62149091061"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/62149091061?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=62149091061&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=62149091061&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/62149091061", "dc:identifier"=>"SCOPUS_ID:62149091061", "eid"=>"2-s2.0-62149091061", "dc:title"=>"Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast", "dc:creator"=>"Roux A.", "prism:publicationName"=>"PLoS Genetics", "prism:issn"=>"15537390", "prism:eIssn"=>"15537404", "prism:volume"=>"5", "prism:issueIdentifier"=>"3", "prism:pageRange"=>nil, "prism:coverDate"=>"2009-03-01", "prism:coverDisplayDate"=>"March 2009", "prism:doi"=>"10.1371/journal.pgen.1000408", "citedby-count"=>"54", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Montreal", "affiliation-city"=>"Montreal", "affiliation-country"=>"Canada"}], "pubmed-id"=>"19266076", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "source-id"=>"4000151808", "openaccess"=>"1", "openaccessFlag"=>true}- {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosgenetics%2Farticle%3Fid%3D10.1371%252Fjournal.pgen.1000408", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}
Counter
- {"month"=>"3", "year"=>"2009", "pdf_views"=>"329", "xml_views"=>"6", "html_views"=>"1154"}
- {"month"=>"4", "year"=>"2009", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"114"}
- {"month"=>"5", "year"=>"2009", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"111"}
- {"month"=>"6", "year"=>"2009", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"130"}
- {"month"=>"7", "year"=>"2009", "pdf_views"=>"19", "xml_views"=>"1", "html_views"=>"87"}
- {"month"=>"8", "year"=>"2009", "pdf_views"=>"19", "xml_views"=>"1", "html_views"=>"57"}
- {"month"=>"9", "year"=>"2009", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"60"}
- {"month"=>"10", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"55"}
- {"month"=>"11", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"86"}
- {"month"=>"12", "year"=>"2009", "pdf_views"=>"19", "xml_views"=>"1", "html_views"=>"58"}
- {"month"=>"1", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"53"}
- {"month"=>"2", "year"=>"2010", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"79"}
- {"month"=>"3", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"2", "html_views"=>"78"}
- {"month"=>"4", "year"=>"2010", "pdf_views"=>"18", "xml_views"=>"3", "html_views"=>"67"}
- {"month"=>"5", "year"=>"2010", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"83"}
- {"month"=>"6", "year"=>"2010", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"74"}
- {"month"=>"7", "year"=>"2010", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"63"}
- {"month"=>"8", "year"=>"2010", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"72"}
- {"month"=>"9", "year"=>"2010", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"50"}
- {"month"=>"10", "year"=>"2010", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"88"}
- {"month"=>"11", "year"=>"2010", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"59"}
- {"month"=>"12", "year"=>"2010", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"32"}
- {"month"=>"1", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"36"}
- {"month"=>"2", "year"=>"2011", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"51"}
- {"month"=>"3", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"67"}
- {"month"=>"4", "year"=>"2011", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"75"}
- {"month"=>"5", "year"=>"2011", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"29"}
- {"month"=>"6", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"37"}
- {"month"=>"7", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"46"}
- {"month"=>"8", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"59"}
- {"month"=>"9", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"74"}
- {"month"=>"10", "year"=>"2011", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"68"}
- {"month"=>"11", "year"=>"2011", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"160"}
- {"month"=>"12", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"150"}
- {"month"=>"1", "year"=>"2012", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"173"}
- {"month"=>"2", "year"=>"2012", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"147"}
- {"month"=>"3", "year"=>"2012", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"114"}
- {"month"=>"4", "year"=>"2012", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"116"}
- {"month"=>"5", "year"=>"2012", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"106"}
- {"month"=>"6", "year"=>"2012", "pdf_views"=>"20", "xml_views"=>"2", "html_views"=>"112"}
- {"month"=>"7", "year"=>"2012", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"92"}
- {"month"=>"8", "year"=>"2012", "pdf_views"=>"14", "xml_views"=>"5", "html_views"=>"69"}
- {"month"=>"9", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"72"}
- {"month"=>"10", "year"=>"2012", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"144"}
- {"month"=>"11", "year"=>"2012", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"174"}
- {"month"=>"12", "year"=>"2012", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"87"}
- {"month"=>"1", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"93"}
- {"month"=>"2", "year"=>"2013", "pdf_views"=>"10", "xml_views"=>"2", "html_views"=>"236"}
- {"month"=>"3", "year"=>"2013", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"105"}
- {"month"=>"4", "year"=>"2013", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"94"}
- {"month"=>"5", "year"=>"2013", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"129"}
- {"month"=>"6", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"109"}
- {"month"=>"7", "year"=>"2013", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"117"}
- {"month"=>"8", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"107"}
- {"month"=>"9", "year"=>"2013", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"80"}
- {"month"=>"10", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"172"}
- {"month"=>"11", "year"=>"2013", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"281"}
- {"month"=>"12", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"269"}
- {"month"=>"1", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"111"}
- {"month"=>"2", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"195"}
- {"month"=>"3", "year"=>"2014", "pdf_views"=>"10", "xml_views"=>"2", "html_views"=>"237"}
- {"month"=>"4", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"203"}
- {"month"=>"5", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"117"}
- {"month"=>"6", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"197"}
- {"month"=>"7", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"200"}
- {"month"=>"8", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"218"}
- {"month"=>"9", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"276"}
- {"month"=>"10", "year"=>"2014", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"348"}
- {"month"=>"11", "year"=>"2014", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"279"}
- {"month"=>"12", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"311"}
- {"month"=>"1", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"180"}
- {"month"=>"2", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"70"}
- {"month"=>"3", "year"=>"2015", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"88"}
- {"month"=>"4", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"58"}
- {"month"=>"5", "year"=>"2015", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"188"}
- {"month"=>"6", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"109"}
- {"month"=>"7", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"74"}
- {"month"=>"8", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"84"}
- {"month"=>"9", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"116"}
- {"month"=>"10", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"135"}
- {"month"=>"11", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"102"}
- {"month"=>"12", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"75"}
- {"month"=>"1", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"90"}
- {"month"=>"2", "year"=>"2016", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"109"}
- {"month"=>"3", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"97"}
- {"month"=>"4", "year"=>"2016", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"112"}
- {"month"=>"5", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"99"}
- {"month"=>"6", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"61"}
- {"month"=>"7", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"68"}
- {"month"=>"8", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"102"}
- {"month"=>"9", "year"=>"2016", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"175"}
- {"month"=>"10", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"110"}
- {"month"=>"11", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"84"}
- {"month"=>"12", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"71"}
- {"month"=>"1", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"81"}
- {"month"=>"2", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"99"}
- {"month"=>"3", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"93"}
- {"month"=>"4", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"68"}
- {"month"=>"5", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"76"}
- {"month"=>"6", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"90"}
- {"month"=>"7", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"69"}
- {"month"=>"8", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"57"}
- {"month"=>"9", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"75"}
- {"month"=>"10", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"67"}
- {"month"=>"11", "year"=>"2017", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"87"}
- {"month"=>"12", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"59"}
- {"month"=>"1", "year"=>"2018", "pdf_views"=>"12", "xml_views"=>"2", "html_views"=>"69"}
- {"month"=>"2", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"36"}
- {"month"=>"3", "year"=>"2018", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"43"}
- {"month"=>"4", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"21"}
- {"month"=>"5", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"23"}
- {"month"=>"6", "year"=>"2018", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"15"}
- {"month"=>"7", "year"=>"2018", "pdf_views"=>"13", "xml_views"=>"5", "html_views"=>"26"}
- {"month"=>"8", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"16"}
- {"month"=>"9", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"15"}
- {"month"=>"10", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"31"}
- {"month"=>"11", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"21"}
- {"month"=>"12", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"16"}
- {"month"=>"1", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"19"}
- {"month"=>"2", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"10"}
- {"month"=>"3", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"15"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"13"}
- {"month"=>"5", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"7"}
- {"month"=>"6", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"5"}
- {"month"=>"7", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"10"}
- {"month"=>"8", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"12"}
- {"month"=>"9", "year"=>"2019", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"12"}
- {"month"=>"10", "year"=>"2019", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"24"}
- {"month"=>"11", "year"=>"2019", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"21"}
- {"month"=>"12", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"5"}
PMC Usage Stats | Further Information
- {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"30", "year"=>"2010", "pdf"=>"10", "unique-ip"=>"29", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"9", "full-text"=>"33", "unique-ip"=>"24", "pdf"=>"9", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"26", "year"=>"2010", "pdf"=>"7", "unique-ip"=>"28", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"37", "unique-ip"=>"29", "pdf"=>"28", "year"=>"2010", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"4"}
- {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"20", "year"=>"2010", "pdf"=>"20", "unique-ip"=>"24", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"17", "unique-ip"=>"18", "pdf"=>"10", "year"=>"2010", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "year"=>"2010", "pdf"=>"11", "unique-ip"=>"13", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"12", "unique-ip"=>"16", "pdf"=>"9", "year"=>"2010", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"2"}
- {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"26", "year"=>"2010", "pdf"=>"22", "unique-ip"=>"25", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"20", "unique-ip"=>"26", "pdf"=>"15", "year"=>"2010", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"28", "year"=>"2010", "pdf"=>"25", "unique-ip"=>"28", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"26", "unique-ip"=>"14", "pdf"=>"5", "year"=>"2010", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"11", "year"=>"2011", "pdf"=>"10", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"8", "unique-ip"=>"17", "pdf"=>"12", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"26", "year"=>"2011", "pdf"=>"11", "unique-ip"=>"23", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"14", "unique-ip"=>"19", "pdf"=>"4", "year"=>"2011", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"4", "full-text"=>"9", "year"=>"2011", "pdf"=>"7", "unique-ip"=>"14", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"18", "unique-ip"=>"21", "pdf"=>"11", "year"=>"2011", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "year"=>"2011", "pdf"=>"6", "unique-ip"=>"14", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"23", "unique-ip"=>"21", "pdf"=>"8", "year"=>"2011", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"9", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "unique-ip"=>"19", "pdf"=>"6", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"13", "year"=>"2011", "pdf"=>"11", "unique-ip"=>"17", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"12", "unique-ip"=>"13", "pdf"=>"6", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "unique-ip"=>"19", "pdf"=>"7", "year"=>"2012", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"13", "year"=>"2012", "pdf"=>"8", "unique-ip"=>"15", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"12", "unique-ip"=>"13", "pdf"=>"4", "year"=>"2012", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"14", "year"=>"2012", "pdf"=>"6", "unique-ip"=>"15", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"20", "unique-ip"=>"19", "pdf"=>"6", "year"=>"2012", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"89", "year"=>"2009", "pdf"=>"65", "unique-ip"=>"80", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"69", "unique-ip"=>"72", "pdf"=>"43", "year"=>"2009", "figure"=>"13", "scanned-summary"=>"0", "supp-data"=>"7"}
- {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"7", "full-text"=>"86", "year"=>"2009", "pdf"=>"90", "unique-ip"=>"54", "figure"=>"19", "scanned-summary"=>"0", "supp-data"=>"14"}
- {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"34", "unique-ip"=>"27", "pdf"=>"19", "year"=>"2009", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"3"}
- {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"23", "year"=>"2009", "pdf"=>"16", "unique-ip"=>"32", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"6"}
- {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"35", "unique-ip"=>"35", "pdf"=>"25", "year"=>"2009", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"8"}
- {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"21", "year"=>"2009", "pdf"=>"12", "unique-ip"=>"28", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"16", "unique-ip"=>"12", "pdf"=>"7", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"8", "full-text"=>"26", "year"=>"2009", "pdf"=>"8", "unique-ip"=>"30", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"16", "unique-ip"=>"13", "pdf"=>"3", "year"=>"2009", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"21", "year"=>"2012", "pdf"=>"11", "unique-ip"=>"17", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
- {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
- {"unique-ip"=>"8", "full-text"=>"12", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
- {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
- {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
- {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
- {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
- {"unique-ip"=>"15", "full-text"=>"17", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
- {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
- {"unique-ip"=>"9", "full-text"=>"5", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2013", "month"=>"6"}
- {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"1", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
- {"unique-ip"=>"11", "full-text"=>"13", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
- {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"25", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
- {"unique-ip"=>"12", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
- {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
- {"unique-ip"=>"11", "full-text"=>"17", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
- {"unique-ip"=>"14", "full-text"=>"16", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
- {"unique-ip"=>"11", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
- {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
- {"unique-ip"=>"19", "full-text"=>"16", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
- {"unique-ip"=>"10", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
- {"unique-ip"=>"15", "full-text"=>"12", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
- {"unique-ip"=>"17", "full-text"=>"13", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
- {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
- {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
- {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
- {"unique-ip"=>"19", "full-text"=>"24", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
- {"unique-ip"=>"8", "full-text"=>"14", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
- {"unique-ip"=>"8", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
- {"unique-ip"=>"14", "full-text"=>"20", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
- {"unique-ip"=>"18", "full-text"=>"22", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
- {"unique-ip"=>"14", "full-text"=>"10", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
- {"unique-ip"=>"17", "full-text"=>"22", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2015", "month"=>"9"}
- {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
- {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
- {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
- {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
- {"unique-ip"=>"23", "full-text"=>"7", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
- {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
- {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
- {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2016", "month"=>"5"}
- {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
- {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
- {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
- {"unique-ip"=>"18", "full-text"=>"23", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
- {"unique-ip"=>"14", "full-text"=>"25", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"11"}
- {"unique-ip"=>"10", "full-text"=>"24", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
- {"unique-ip"=>"9", "full-text"=>"17", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2017", "month"=>"1"}
- {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
- {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
- {"unique-ip"=>"5", "full-text"=>"2", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
- {"unique-ip"=>"6", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
- {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
- {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
- {"unique-ip"=>"7", "full-text"=>"16", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
- {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
- {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
- {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
- {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
- {"unique-ip"=>"9", "full-text"=>"32", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
- {"unique-ip"=>"13", "full-text"=>"33", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
- {"unique-ip"=>"10", "full-text"=>"12", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
- {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
- {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
- {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
- {"unique-ip"=>"8", "full-text"=>"10", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
- {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
- {"unique-ip"=>"12", "full-text"=>"13", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
- {"unique-ip"=>"18", "full-text"=>"15", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
- {"unique-ip"=>"15", "full-text"=>"19", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
- {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
- {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
- {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
Relative Metric
{"start_date"=>"2009-01-01T00:00:00Z", "end_date"=>"2009-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[349, 614, 744, 851, 955, 1059, 1167, 1262, 1352, 1431, 1516, 1593, 1668, 1746, 1817, 1883, 1950, 2017, 2075, 2141, 2198, 2254, 2313, 2368, 2424, 2474, 2534, 2591, 2651, 2710, 2776, 2837, 2892, 2953, 3014, 3072, 3130, 3186, 3251, 3307, 3366, 3427, 3500, 3561, 3627, 3688, 3759, 3821, 3888, 3950, 4010, 4070, 4131, 4189, 4242, 4307, 4370, 4431, 4491, 4549, 4608]}, {"subject_area"=>"/Biology and life sciences/Biochemistry", "average_usage"=>[335, 600, 731, 835, 935, 1034, 1138, 1230, 1320, 1399, 1485, 1570, 1643, 1714, 1791, 1859, 1928, 1987, 2040, 2104, 2157, 2210, 2261, 2320, 2373, 2432, 2486, 2543, 2603, 2655, 2720, 2787, 2844, 2901, 2952, 3005, 3065, 3119, 3176, 3236, 3305, 3373, 3432, 3492, 3558, 3614, 3676, 3736, 3801, 3869, 3930, 3973, 4031, 4096, 4176, 4234, 4283, 4338, 4405, 4464, 4512]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[340, 575, 698, 803, 889, 974, 1077, 1169, 1245, 1318, 1398, 1468, 1540, 1608, 1679, 1748, 1819, 1877, 1937, 1999, 2044, 2100, 2148, 2198, 2250, 2306, 2357, 2414, 2458, 2517, 2572, 2636, 2690, 2749, 2799, 2861, 2914, 2970, 3026, 3102, 3143, 3237, 3303, 3373, 3441, 3500, 3553, 3608, 3679, 3733, 3791, 3856, 3908, 3962, 4033, 4096, 4149, 4187, 4229, 4281, 4336]}]}Loading … 

There are currently no alerts