CiteULike

Mendeley | Further Information

{"title"=>"Prolonged Activation of Virus-Specific CD8+T Cells after Acute B19 Infection", "type"=>"journal", "authors"=>[{"first_name"=>"Adiba", "last_name"=>"Isa"}, {"first_name"=>"Victoria", "last_name"=>"Kasprowicz"}, {"first_name"=>"Oscar", "last_name"=>"Norbeck"}, {"first_name"=>"Andrew", "last_name"=>"Loughry"}, {"first_name"=>"Katie", "last_name"=>"Jeffery"}, {"first_name"=>"Kristina", "last_name"=>"Broliden"}, {"first_name"=>"Paul", "last_name"=>"Klenerman"}, {"first_name"=>"Thomas", "last_name"=>"Tolfvenstam"}, {"first_name"=>"Paul", "last_name"=>"Bowness"}], "year"=>2005, "source"=>"PLoS Medicine", "identifiers"=>{"pmid"=>"16253012", "doi"=>"10.1371/journal.pmed.0020343", "issn"=>"1549-1676"}, "id"=>"e3335dac-c0a3-34b2-b6c8-9ac6df668347", "abstract"=>"BACKGROUND: Human parvovirus B19 (B19) is a ubiquitous and clinically significant pathogen, causing erythema infectiosum, arthropathy, transient aplastic crisis, and intrauterine fetal death. The phenotype of CD8+ T cells in acute B19 infection has not been studied previously.\\n\\nMETHODS AND FINDINGS: The number and phenotype of B19-specific CD8+ T cell responses during and after acute adult infection was studied using HLA-peptide multimeric complexes. Surprisingly, these responses increased in magnitude over the first year post-infection despite resolution of clinical symptoms and control of viraemia, with T cell populations specific for individual epitopes comprising up to 4% of CD8+ T cells. B19-specific T cells developed and maintained an activated CD38+ phenotype, with strong expression of perforin and CD57 and downregulation of CD28 and CD27. These cells possessed strong effector function and intact proliferative capacity. Individuals tested many years after infection exhibited lower frequencies of B19-specific cytotoxic T lymphocytes, typically 0.05%-0.5% of CD8+ T cells, which were perforin, CD38, and CCR7 low.\\n\\nCONCLUSION: This is the first example to our knowledge of an \"acute\" human viral infection inducing a persistent activated CD8+ T cell response. The likely explanation--analogous to that for cytomegalovirus infection--is that this persistent response is due to low-level antigen exposure. CD8+ T cells may contribute to the long-term control of this significant pathogen and should be considered during vaccine development.", "link"=>"http://www.mendeley.com/research/prolonged-activation-virusspecific-cd8t-cells-after-acute-b19-infection", "reader_count"=>9, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>3, "Researcher"=>4, "Student > Ph. D. Student"=>1, "Student > Master"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>3, "Researcher"=>4, "Student > Ph. D. Student"=>1, "Student > Master"=>1}, "reader_count_by_subject_area"=>{"Biochemistry, Genetics and Molecular Biology"=>1, "Medicine and Dentistry"=>4, "Agricultural and Biological Sciences"=>3, "Immunology and Microbiology"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>4}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}}, "group_count"=>1}

ORCID

CrossRef

• http://doi.org/10.1016/j.cca.2006.04.018
• http://doi.org/10.1007/s00223-016-0212-9
• http://doi.org/10.1089/aid.2015.0115
• http://doi.org/10.1371/journal.pone.0002361
• http://doi.org/10.1007/s00296-009-1262-3
• http://doi.org/10.3201/eid1610.101001
• http://doi.org/10.1002/rmv.1839
• http://doi.org/10.1098/rsif.2006.0195
• http://doi.org/10.1086/526533
• http://doi.org/10.3201/eid1309.070428
• http://doi.org/10.1016/j.transproceed.2006.06.116
• http://doi.org/10.1111/j.1365-2249.2006.03286.x
• http://doi.org/10.1128/JVI.01024-18
• http://doi.org/10.1111/j.1365-2567.2011.03470.x
• http://doi.org/10.1128/JVI.02793-12
• http://doi.org/10.1111/imr.12653
• http://doi.org/10.1038/nri.2016.38
• http://doi.org/10.1111/j.1365-2796.2006.01697.x
• http://doi.org/10.1111/j.1537-2995.2007.01459.x
• http://doi.org/10.1016/j.it.2011.11.005
• http://doi.org/10.1016/j.rdc.2009.03.004
• http://doi.org/10.5402/2013/898730
• http://doi.org/10.1136/jclinpath-2015-203455
• http://doi.org/10.1007/s00430-019-00608-7
• http://doi.org/10.1017/S0950268807009661
• http://doi.org/10.1016/j.virol.2007.07.007
• http://doi.org/10.1517/17530050903452190
• http://doi.org/10.1200/JCO.2006.10.2251
• http://doi.org/10.1038/ncpneph0609
• http://doi.org/10.1089/hum.2011.108
• http://doi.org/10.4049/jimmunol.0803903
• http://doi.org/10.1371/journal.ppat.1007785
• http://doi.org/10.1371/journal.ppat.1004233
• http://doi.org/10.1093/infdis/jir036
• http://doi.org/10.1038/icb.2010.155
• http://doi.org/10.1086/528804
• http://doi.org/10.2215/CJN.01060307
• http://doi.org/10.1111/j.1471-0528.2010.02749.x
• http://doi.org/10.1111/j.1399-3046.2010.01291.x
• http://doi.org/10.4049/jimmunol.1202665
• http://doi.org/10.1016/j.lpm.2012.04.023
• http://doi.org/10.1539/joh.L9042
• http://doi.org/10.1016/j.jcv.2009.11.015
• http://doi.org/10.1038/cti.2015.13
• http://doi.org/10.1111/j.1537-2995.2011.03420.x
• http://doi.org/10.1002/jmv.21360
• http://doi.org/10.1189/jlb.0809566
• http://doi.org/10.1159/000116723
• http://doi.org/10.1189/jlb.0107073

DataCite

Europe PMC Citations | Further Information

Europe PMC Database Citations

PubMed Central

• 2708529
• 1488968
• 1642156
• 2447064
• 2937825
• 3592128
• 2629660
• 2782623
• 2914696
• 3059196
• 3374958
• 2870907
• 1810484
• 3173691
• 4081724
• 3672979
• 2373406
• 2394660
• 2857296
• 3294412
• 3404422
• 3080894
• 3856678
• 4524951

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/29644434828"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/29644434828?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=29644434828&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=29644434828&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/29644434828", "dc:identifier"=>"SCOPUS_ID:29644434828", "eid"=>"2-s2.0-29644434828", "dc:title"=>"Prolonged activation of virus-specific CD8⁺ T cells after acute B19 infection", "dc:creator"=>"Isa A.", "prism:publicationName"=>"PLoS Medicine", "prism:issn"=>"15491277", "prism:eIssn"=>"15491676", "prism:volume"=>"2", "prism:issueIdentifier"=>"12", "prism:pageRange"=>"1280-1291", "prism:coverDate"=>"2005-12-01", "prism:coverDisplayDate"=>"December 2005", "prism:doi"=>"10.1371/journal.pmed.0020343", "citedby-count"=>"66", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Karolinska University Hospital", "affiliation-city"=>"Stockholm", "affiliation-country"=>"Sweden"}], "pubmed-id"=>"16253012", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e343", "source-id"=>"144840", "openaccess"=>"1", "openaccessFlag"=>true}

Web of Science® | Further Information

Article Coverage

Article Coverage Curated

Facebook

• {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosmedicine%2Farticle%3Fid%3D10.1371%252Fjournal.pmed.0020343", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments

Nature

Reddit

Research Blogging

ScienceSeeker | Further Information

Twitter

Wikipedia

Wordpress.com | Further Information

Counter

• {"month"=>"10", "year"=>"2005", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"11", "year"=>"2005", "pdf_views"=>"115", "xml_views"=>"0", "html_views"=>"259"}
• {"month"=>"12", "year"=>"2005", "pdf_views"=>"55", "xml_views"=>"1", "html_views"=>"124"}
• {"month"=>"1", "year"=>"2006", "pdf_views"=>"74", "xml_views"=>"1", "html_views"=>"196"}
• {"month"=>"2", "year"=>"2006", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"97"}
• {"month"=>"3", "year"=>"2006", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"68"}
• {"month"=>"4", "year"=>"2006", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"48"}
• {"month"=>"5", "year"=>"2006", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"52"}
• {"month"=>"6", "year"=>"2006", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"48"}
• {"month"=>"7", "year"=>"2006", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"49"}
• {"month"=>"8", "year"=>"2006", "pdf_views"=>"12", "xml_views"=>"2", "html_views"=>"65"}
• {"month"=>"9", "year"=>"2006", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"31"}
• {"month"=>"10", "year"=>"2006", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"31"}
• {"month"=>"11", "year"=>"2006", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"63"}
• {"month"=>"12", "year"=>"2006", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"14"}
• {"month"=>"1", "year"=>"2007", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"25"}
• {"month"=>"2", "year"=>"2007", "pdf_views"=>"6", "xml_views"=>"4", "html_views"=>"27"}
• {"month"=>"3", "year"=>"2007", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"21"}
• {"month"=>"4", "year"=>"2007", "pdf_views"=>"4", "xml_views"=>"3", "html_views"=>"17"}
• {"month"=>"5", "year"=>"2007", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"18"}
• {"month"=>"6", "year"=>"2007", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"23"}
• {"month"=>"7", "year"=>"2007", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
• {"month"=>"8", "year"=>"2007", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"20"}
• {"month"=>"9", "year"=>"2007", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"10", "year"=>"2007", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"12"}
• {"month"=>"11", "year"=>"2007", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"19"}
• {"month"=>"12", "year"=>"2007", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"13"}
• {"month"=>"1", "year"=>"2008", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"24"}
• {"month"=>"2", "year"=>"2008", "pdf_views"=>"5", "xml_views"=>"3", "html_views"=>"17"}
• {"month"=>"3", "year"=>"2008", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"20"}
• {"month"=>"4", "year"=>"2008", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"20"}
• {"month"=>"5", "year"=>"2008", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"24"}
• {"month"=>"6", "year"=>"2008", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"65"}
• {"month"=>"7", "year"=>"2008", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"23"}
• {"month"=>"8", "year"=>"2008", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
• {"month"=>"9", "year"=>"2008", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"25"}
• {"month"=>"10", "year"=>"2008", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"25"}
• {"month"=>"11", "year"=>"2008", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"19"}
• {"month"=>"12", "year"=>"2008", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"10"}
• {"month"=>"1", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"9"}
• {"month"=>"2", "year"=>"2009", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"3", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"19"}
• {"month"=>"4", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"11"}
• {"month"=>"5", "year"=>"2009", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"5"}
• {"month"=>"6", "year"=>"2009", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"9"}
• {"month"=>"7", "year"=>"2009", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"12"}
• {"month"=>"8", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"18"}
• {"month"=>"9", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"15"}
• {"month"=>"10", "year"=>"2009", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
• {"month"=>"11", "year"=>"2009", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"29"}
• {"month"=>"12", "year"=>"2009", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
• {"month"=>"1", "year"=>"2010", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"24"}
• {"month"=>"2", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"18"}
• {"month"=>"3", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"18"}
• {"month"=>"4", "year"=>"2010", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"37"}
• {"month"=>"5", "year"=>"2010", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"27"}
• {"month"=>"6", "year"=>"2010", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"34"}
• {"month"=>"7", "year"=>"2010", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"39"}
• {"month"=>"8", "year"=>"2010", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"22"}
• {"month"=>"9", "year"=>"2010", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"20"}
• {"month"=>"10", "year"=>"2010", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"24"}
• {"month"=>"11", "year"=>"2010", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
• {"month"=>"12", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"1", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"13"}
• {"month"=>"2", "year"=>"2011", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"12"}
• {"month"=>"3", "year"=>"2011", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"14"}
• {"month"=>"4", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"10"}
• {"month"=>"5", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"5"}
• {"month"=>"6", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"11"}
• {"month"=>"7", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
• {"month"=>"8", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"7"}
• {"month"=>"9", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}
• {"month"=>"10", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"11"}
• {"month"=>"11", "year"=>"2011", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"8"}
• {"month"=>"12", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"18"}
• {"month"=>"1", "year"=>"2012", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
• {"month"=>"2", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"3", "year"=>"2012", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"18"}
• {"month"=>"4", "year"=>"2012", "pdf_views"=>"10", "xml_views"=>"2", "html_views"=>"34"}
• {"month"=>"5", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"17"}
• {"month"=>"6", "year"=>"2012", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"11"}
• {"month"=>"7", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"15"}
• {"month"=>"8", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"6", "html_views"=>"64"}
• {"month"=>"9", "year"=>"2012", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
• {"month"=>"10", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"17"}
• {"month"=>"11", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"31"}
• {"month"=>"12", "year"=>"2012", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
• {"month"=>"1", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"29"}
• {"month"=>"2", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"28"}
• {"month"=>"3", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"26"}
• {"month"=>"4", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"45"}
• {"month"=>"5", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"30"}
• {"month"=>"6", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"26"}
• {"month"=>"7", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"24"}
• {"month"=>"8", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"4", "html_views"=>"28"}
• {"month"=>"9", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"40"}
• {"month"=>"10", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"51"}
• {"month"=>"11", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"50"}
• {"month"=>"12", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"50"}
• {"month"=>"1", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"58"}
• {"month"=>"2", "year"=>"2014", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"40"}
• {"month"=>"3", "year"=>"2014", "pdf_views"=>"0", "xml_views"=>"2", "html_views"=>"59"}
• {"month"=>"4", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"5", "html_views"=>"76"}
• {"month"=>"5", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"54"}
• {"month"=>"6", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"47"}
• {"month"=>"7", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"60"}
• {"month"=>"8", "year"=>"2014", "pdf_views"=>"0", "xml_views"=>"3", "html_views"=>"38"}
• {"month"=>"9", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"45"}
• {"month"=>"10", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"56"}
• {"month"=>"11", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"68"}
• {"month"=>"12", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"61"}
• {"month"=>"1", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"51"}
• {"month"=>"2", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"21"}
• {"month"=>"3", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"9"}
• {"month"=>"4", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"15"}
• {"month"=>"5", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"13"}
• {"month"=>"6", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"14"}
• {"month"=>"7", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"13"}
• {"month"=>"8", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"9"}
• {"month"=>"9", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"12"}
• {"month"=>"10", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"12"}
• {"month"=>"11", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"3"}
• {"month"=>"12", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"5"}
• {"month"=>"1", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"21"}
• {"month"=>"2", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"5"}
• {"month"=>"3", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"96"}
• {"month"=>"4", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"79"}
• {"month"=>"5", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"35"}
• {"month"=>"6", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"43"}
• {"month"=>"7", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"55"}
• {"month"=>"8", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"72"}
• {"month"=>"9", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"65"}
• {"month"=>"10", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"77"}
• {"month"=>"11", "year"=>"2016", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"71"}
• {"month"=>"12", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"43"}
• {"month"=>"1", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"47"}
• {"month"=>"2", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"61"}
• {"month"=>"3", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"46"}
• {"month"=>"4", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"37"}
• {"month"=>"5", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"73"}
• {"month"=>"6", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"50"}
• {"month"=>"7", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"56"}
• {"month"=>"8", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"21"}
• {"month"=>"9", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"29"}
• {"month"=>"10", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"3", "html_views"=>"60"}
• {"month"=>"11", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"67"}
• {"month"=>"12", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"47"}
• {"month"=>"1", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"36"}
• {"month"=>"2", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"37"}
• {"month"=>"3", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"27"}
• {"month"=>"4", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"12"}
• {"month"=>"5", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"36"}
• {"month"=>"6", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"3", "html_views"=>"9"}
• {"month"=>"7", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"6", "html_views"=>"5"}
• {"month"=>"8", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"3"}
• {"month"=>"9", "year"=>"2018", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"2"}
• {"month"=>"10", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"9"}
• {"month"=>"11", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"6"}
• {"month"=>"12", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"2"}
• {"month"=>"1", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"4"}
• {"month"=>"2", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"3"}
• {"month"=>"3", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"6"}
• {"month"=>"4", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"3"}
• {"month"=>"5", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"9"}
• {"month"=>"6", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"4"}
• {"month"=>"7", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"2"}
• {"month"=>"8", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"4"}
• {"month"=>"9", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"5"}
• {"month"=>"10", "year"=>"2019", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"5"}
• {"month"=>"11", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"1"}
• {"month"=>"12", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"6"}
• {"month"=>"1", "year"=>"2020", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"2"}
• {"month"=>"2", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"2"}

Figshare

• {"files"=>["https://ndownloader.figshare.com/files/961425"], "description"=>"<div><p>(A) Representative A24 FYT tetramer staining of individual O3\\′s PBMCs. Plots are gated on live CD8⁺ lymphocytes stained directly ex vivo. Percentages shown are those of tetramer-positive CD8⁺ T cells. Time points indicated refer to the number of months after first symptoms reported. Symptoms in this individual lasted 5 wk.</p>\n <p>(B) Frequency of B19-specific responses over time for six acutely infected individuals in the Oxford cohort (O1–O5) and five remotely infected individuals (OR1–OR5). In one case, two epitopes were studied.</p>\n <p>(C) Frequency of B19-specific responses over time for five acutely infected individuals in the Stockholm cohort (S1–S5). In two cases, two epitopes were studied.</p></div>", "links"=>[], "tags"=>["cells", "months", "acute"], "article_id"=>631408, "categories"=>["Cell Biology", "Microbiology", "Hematology", "Virology", "Infectious Diseases", "Immunology"], "users"=>["Adiba Isa", "Victoria Kasprowicz", "Oscar Norbeck", "Andrew Loughry", "Katie Jeffery", "Kristina Broliden", "Paul Klenerman", "Thomas Tolfvenstam", "Paul Bowness"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020343.g001", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_B19_Specific_CD8_T_Cells_Persist_at_High_Levels_for_Many_Months_after_Acute_Infection_/631408", "title"=>"B19-Specific CD8⁺ T Cells Persist at High Levels for Many Months after Acute Infection", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:57:12"}
• {"files"=>["https://ndownloader.figshare.com/files/961832"], "description"=>"<div><p>(A) Blood from patient S1 was stained with the two tetramers A2 LLH and A2 GLC.</p>\n <p>(B) Blood from patient S2 was stained with tetramers A2 GLC and the Pro5 B40 TEA pentamer. The top panels show the frequency of tetramer-positive cells over time for the two different responses in each individual (data equivalent to those in <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020343#pmed-0020343-g001\" target=\"_blank\">Figure 1</a>C). The subsequent panels show the frequency of B19-specific CD8⁺ cells positive for perforin, CD38, CD57, and CD62L in both patients.</p></div>", "links"=>[], "tags"=>["phenotype", "b19-specific", "responses", "acutely", "infected", "individuals", "stockholm"], "article_id"=>631808, "categories"=>["Cell Biology", "Microbiology", "Hematology", "Virology", "Infectious Diseases", "Immunology"], "users"=>["Adiba Isa", "Victoria Kasprowicz", "Oscar Norbeck", "Andrew Loughry", "Katie Jeffery", "Kristina Broliden", "Paul Klenerman", "Thomas Tolfvenstam", "Paul Bowness"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020343.g004", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Longitudinal_Phenotype_Analysis_of_B19_Specific_CD8_T_Cell_Responses_in_Acutely_Infected_Individuals_in_Stockholm_Cohort_/631808", "title"=>"Longitudinal Phenotype Analysis of B19-Specific CD8⁺ T Cell Responses in Acutely Infected Individuals in Stockholm Cohort", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:59:58"}
• {"files"=>["https://ndownloader.figshare.com/files/961958"], "description"=>"<div><p>(A) Left panel shows that PBMCs from acutely infected patient O1 secrete IFNγ ex vivo after 18 h of FYTPLADQF peptide stimulation. Negative control (zero spots) and two peptide-stimulated wells from an ELISpot plate are shown. Numbers represent IFNγ-secreting cells per 250,000 PBMCs. Right panel shows A24 FYT tetramer staining of PBMCs at same time point, displaying the number of tetramer-positive cells expressed as a percentage of CD8⁺ T cells.</p>\n <p>(B) Tetramer staining of patient S2\\′s PBMCs ex vivo (left) and after short-term TEADVQQWL peptide stimulation in vitro (right).</p>\n <p>(C) Ex vivo IFNγ ELISpot results for remotely infected individual OR3. Mean and standard deviations of triplicates are shown. Cells were stimulated for 18 h with no peptide, GLCPHCINV, or TEADVQQWL.</p>\n <p>(D) ⁵¹Cr release assay using HLA-A2-restricted GLCPHCINV-specific CTLs from individual OR1. PBMCs were stimulated for 14 d with GLCPHCINV peptide and cytolysis was tested against HLA-A*0201-transfected LBL.721.220 target cells at various effector-to-target-cell (E:T) ratios.</p></div>", "links"=>[], "tags"=>["cells", "secrete", "ex", "cytolytic"], "article_id"=>631936, "categories"=>["Cell Biology", "Microbiology", "Hematology", "Virology", "Infectious Diseases", "Immunology"], "users"=>["Adiba Isa", "Victoria Kasprowicz", "Oscar Norbeck", "Andrew Loughry", "Katie Jeffery", "Kristina Broliden", "Paul Klenerman", "Thomas Tolfvenstam", "Paul Bowness"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020343.g005", "stats"=>{"downloads"=>0, "page_views"=>32, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_B19_Specific_CD8_T_Cells_Secrete_IFN_947_Ex_Vivo_Proliferate_and_Show_Cytolytic_Function_In_Vitro_/631936", "title"=>"B19-Specific CD8⁺ T Cells Secrete IFNγ Ex Vivo, Proliferate, and Show Cytolytic Function In Vitro", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 09:00:55"}
• {"files"=>["https://ndownloader.figshare.com/files/961528"], "description"=>"<div><p>Percentages shown are the frequency of marker-positive cells amongst multimer-positive cells (plots gated on live CD8⁺ lymphocytes ex vivo).</p>\n <p>(A) Patient S2 B40 TEA pentamer staining at 4 mo (left) and 21 mo (right), showing perforin and CD62L levels.</p>\n <p>(B) Patient O3 A24 FYT tetramer staining at 2 mo (left) and 20 mo (right), showing CD27 and CD28 staining.</p>\n <p>(C) Patient O5 A2 GLC tetramer staining at 4 mo (left) and 18 mo (right), showing CD38 and CD57 staining.</p></div>", "links"=>[], "tags"=>["ex", "vivo", "phenotyping", "b19-specific", "populations"], "article_id"=>631508, "categories"=>["Cell Biology", "Microbiology", "Hematology", "Virology", "Infectious Diseases", "Immunology"], "users"=>["Adiba Isa", "Victoria Kasprowicz", "Oscar Norbeck", "Andrew Loughry", "Katie Jeffery", "Kristina Broliden", "Paul Klenerman", "Thomas Tolfvenstam", "Paul Bowness"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020343.g002", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Representative_Ex_Vivo_Phenotyping_of_B19_Specific_CD8_T_Cell_Populations_over_Time_/631508", "title"=>"Representative Ex Vivo Phenotyping of B19-Specific CD8⁺ T Cell Populations over Time", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:57:53"}
• {"files"=>["https://ndownloader.figshare.com/files/961669"], "description"=>"<p>Remotely infected individuals show a less mature/activated phenotype but express only low levels of CCR7 and CD62L (Oxford cohort). The y-axis show the frequency of marker-positive cells amongst tetramer-positive CD8⁺ cells, while the x-axis show the number of months after symptom onset. Data are shown in perforin, CD38, CD57, CD27, CD28, and CCR7: data are derived from six acutely infected individuals in the Oxford cohort (O1–O3, O5, and O6; insufficient cells available for O4) and five remotely infected individuals (OR1–OR5).</p>", "links"=>[], "tags"=>["infected", "individuals", "activated", "mature", "effector", "cells", "acute"], "article_id"=>631646, "categories"=>["Cell Biology", "Microbiology", "Hematology", "Virology", "Infectious Diseases", "Immunology"], "users"=>["Adiba Isa", "Victoria Kasprowicz", "Oscar Norbeck", "Andrew Loughry", "Katie Jeffery", "Kristina Broliden", "Paul Klenerman", "Thomas Tolfvenstam", "Paul Bowness"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020343.g003", "stats"=>{"downloads"=>2, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Acutely_infected_individuals_Maintain_Activated_Mature_Effector_Cells_after_Resolution_of_Acute_Infection_/631646", "title"=>"Acutely infected individuals Maintain Activated Mature Effector Cells after Resolution of Acute Infection", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:58:51"}

PMC Usage Stats | Further Information

• {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"3", "year"=>"2010", "pdf"=>"3", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"5", "pdf"=>"1", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2010", "pdf"=>"3", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "unique-ip"=>"5", "pdf"=>"4", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"6", "year"=>"2010", "pdf"=>"5", "unique-ip"=>"10", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"2", "pdf"=>"1", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "year"=>"2010", "pdf"=>"6", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"1", "unique-ip"=>"4", "pdf"=>"2", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"1", "year"=>"2010", "pdf"=>"5", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"6", "full-text"=>"5", "unique-ip"=>"11", "pdf"=>"3", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "year"=>"2010", "pdf"=>"1", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"5", "unique-ip"=>"7", "pdf"=>"1", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"4", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"2", "abstract"=>"3", "full-text"=>"11", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"14", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"6", "unique-ip"=>"13", "pdf"=>"6", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"3", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"5", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"3", "unique-ip"=>"5", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"1", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"4", "pdf"=>"4", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"3", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"3", "pdf"=>"1", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"5", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2012", "pdf"=>"2", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"2", "pdf"=>"0", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"4", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"4", "pdf"=>"1", "year"=>"2012", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2012", "pdf"=>"2", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"37", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"1", "pdf"=>"0", "year"=>"2005", "figure"=>"69", "scanned-summary"=>"29", "supp-data"=>"27"}
• {"month"=>"1", "scanned-page-browse"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"38", "scanned-summary"=>"29", "supp-data"=>"33"}
• {"scanned-page-browse"=>"17", "month"=>"2", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"5", "pdf"=>"0", "year"=>"2006", "figure"=>"57", "scanned-summary"=>"35", "supp-data"=>"32"}
• {"month"=>"3", "scanned-page-browse"=>"18", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"11", "figure"=>"70", "scanned-summary"=>"38", "supp-data"=>"30"}
• {"scanned-page-browse"=>"10", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"1", "pdf"=>"0", "year"=>"2006", "figure"=>"37", "scanned-summary"=>"24", "supp-data"=>"24"}
• {"month"=>"5", "scanned-page-browse"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"32", "scanned-summary"=>"19", "supp-data"=>"22"}
• {"scanned-page-browse"=>"10", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2006", "figure"=>"44", "scanned-summary"=>"34", "supp-data"=>"31"}
• {"month"=>"7", "scanned-page-browse"=>"14", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"6", "figure"=>"54", "scanned-summary"=>"33", "supp-data"=>"38"}
• {"scanned-page-browse"=>"16", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"5", "pdf"=>"0", "year"=>"2006", "figure"=>"43", "scanned-summary"=>"20", "supp-data"=>"18"}
• {"month"=>"9", "scanned-page-browse"=>"15", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"61", "scanned-summary"=>"45", "supp-data"=>"38"}
• {"scanned-page-browse"=>"18", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"2", "pdf"=>"0", "year"=>"2006", "figure"=>"56", "scanned-summary"=>"34", "supp-data"=>"33"}
• {"month"=>"11", "scanned-page-browse"=>"11", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"1", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"5", "figure"=>"51", "scanned-summary"=>"33", "supp-data"=>"32"}
• {"scanned-page-browse"=>"13", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2006", "figure"=>"41", "scanned-summary"=>"26", "supp-data"=>"22"}
• {"month"=>"1", "scanned-page-browse"=>"11", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"1", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"6", "figure"=>"37", "scanned-summary"=>"18", "supp-data"=>"21"}
• {"scanned-page-browse"=>"17", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2007", "figure"=>"42", "scanned-summary"=>"25", "supp-data"=>"24"}
• {"month"=>"3", "scanned-page-browse"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"1", "figure"=>"22", "scanned-summary"=>"14", "supp-data"=>"12"}
• {"scanned-page-browse"=>"6", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"0", "unique-ip"=>"3", "pdf"=>"0", "year"=>"2007", "figure"=>"28", "scanned-summary"=>"18", "supp-data"=>"23"}
• {"month"=>"5", "scanned-page-browse"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"15", "scanned-summary"=>"12", "supp-data"=>"11"}
• {"scanned-page-browse"=>"4", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2007", "figure"=>"14", "scanned-summary"=>"10", "supp-data"=>"12"}
• {"month"=>"7", "scanned-page-browse"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"8", "scanned-summary"=>"5", "supp-data"=>"5"}
• {"scanned-page-browse"=>"5", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"2", "pdf"=>"0", "year"=>"2007", "figure"=>"19", "scanned-summary"=>"12", "supp-data"=>"9"}
• {"month"=>"9", "scanned-page-browse"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"1", "figure"=>"23", "scanned-summary"=>"14", "supp-data"=>"13"}
• {"scanned-page-browse"=>"3", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"2", "pdf"=>"0", "year"=>"2007", "figure"=>"20", "scanned-summary"=>"15", "supp-data"=>"13"}
• {"month"=>"11", "scanned-page-browse"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"11", "scanned-summary"=>"8", "supp-data"=>"9"}
• {"scanned-page-browse"=>"5", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2007", "figure"=>"8", "scanned-summary"=>"3", "supp-data"=>"4"}
• {"month"=>"1", "scanned-page-browse"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"5", "figure"=>"26", "scanned-summary"=>"14", "supp-data"=>"16"}
• {"scanned-page-browse"=>"5", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2008", "figure"=>"13", "scanned-summary"=>"8", "supp-data"=>"9"}
• {"month"=>"3", "scanned-page-browse"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"30", "scanned-summary"=>"18", "supp-data"=>"17"}
• {"scanned-page-browse"=>"4", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2008", "figure"=>"13", "scanned-summary"=>"9", "supp-data"=>"8"}
• {"month"=>"5", "scanned-page-browse"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"18", "scanned-summary"=>"10", "supp-data"=>"9"}
• {"scanned-page-browse"=>"2", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"6", "pdf"=>"0", "year"=>"2008", "figure"=>"20", "scanned-summary"=>"12", "supp-data"=>"11"}
• {"month"=>"7", "scanned-page-browse"=>"5", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"17", "scanned-summary"=>"12", "supp-data"=>"12"}
• {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2008", "figure"=>"9", "scanned-summary"=>"6", "supp-data"=>"9"}
• {"month"=>"9", "scanned-page-browse"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"0", "figure"=>"9", "scanned-summary"=>"4", "supp-data"=>"8"}
• {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "unique-ip"=>"10", "pdf"=>"6", "year"=>"2008", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"8", "year"=>"2008", "pdf"=>"11", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"4", "pdf"=>"2", "year"=>"2008", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"2", "abstract"=>"2", "full-text"=>"9", "year"=>"2009", "pdf"=>"4", "unique-ip"=>"7", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "unique-ip"=>"8", "pdf"=>"5", "year"=>"2009", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"8", "year"=>"2009", "pdf"=>"3", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "unique-ip"=>"6", "pdf"=>"2", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2009", "pdf"=>"4", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"10", "unique-ip"=>"10", "pdf"=>"3", "year"=>"2009", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"12", "year"=>"2009", "pdf"=>"2", "unique-ip"=>"12", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"6", "unique-ip"=>"7", "pdf"=>"0", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2009", "pdf"=>"2", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"3", "unique-ip"=>"4", "pdf"=>"0", "year"=>"2009", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"7", "year"=>"2009", "pdf"=>"3", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"8", "unique-ip"=>"8", "pdf"=>"4", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2012", "pdf"=>"0", "unique-ip"=>"3", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
• {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
• {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
• {"unique-ip"=>"2", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
• {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"4", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
• {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
• {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
• {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
• {"unique-ip"=>"6", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
• {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
• {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
• {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
• {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
• {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
• {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
• {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
• {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
• {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
• {"unique-ip"=>"9", "full-text"=>"11", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
• {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
• {"unique-ip"=>"5", "full-text"=>"10", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
• {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
• {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
• {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
• {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
• {"unique-ip"=>"12", "full-text"=>"9", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
• {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
• {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
• {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
• {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
• {"unique-ip"=>"2", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
• {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
• {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
• {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
• {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
• {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"11"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
• {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
• {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
• {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
• {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
• {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
• {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
• {"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
• {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"29", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
• {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
• {"unique-ip"=>"4", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
• {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
• {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
• {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
• {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
• {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
• {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
• {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
• {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
• {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
• {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
• {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
• {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
• {"unique-ip"=>"5", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
• {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
• {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
• {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
• {"unique-ip"=>"10", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
• {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
• {"unique-ip"=>"3", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
• {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
• {"unique-ip"=>"4", "full-text"=>"1", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}

Relative Metric

{"start_date"=>"2005-01-01T00:00:00Z", "end_date"=>"2005-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[336, 850, 1136, 1314, 1437, 1543, 1660, 1753, 1866, 1969, 2054, 2137, 2193, 2259, 2328, 2404, 2474, 2541, 2613, 2661, 2713, 2771, 2824, 2867, 2921, 2946, 2973, 3030, 3059, 3083, 3133, 3179, 3218, 3275, 3320, 3367, 3413, 3468, 3531, 3571, 3642, 3689, 3715, 3772, 3830, 3872, 3926, 3971, 4005, 4046, 4094, 4133, 4162, 4200, 4242, 4285, 4302, 4355, 4410, 4463, 4507, 4542, 4587, 4629, 4665, 4697, 4741, 4769, 4809, 4836, 4873, 4905, 4933, 4981, 5004, 5036, 5068, 5106, 5162, 5212, 5270, 5326, 5407, 5462, 5502, 5562, 5609, 5668, 5733, 5791, 5816, 5878, 5907, 5985, 6117, 6206, 6262, 6304, 6356, 6419, 6489, 6562, 6610, 6674, 6707, 6764, 6821, 6871, 6908]}, {"subject_area"=>"/Biology and life sciences/Anatomy and physiology", "average_usage"=>[350, 850, 1120, 1274, 1434, 1549, 1623, 1696, 1756, 1859, 1931, 2006, 2053, 2164, 2291, 2319, 2351, 2398, 2481, 2546, 2593, 2630, 2666, 2710, 2762, 2782, 2810, 2837, 2864, 2891, 2958, 2979, 3000, 3103, 3170, 3244, 3283, 3314, 3346, 3377, 3418, 3484, 3533, 3607, 3636, 3660, 3681, 3708, 3747, 3784, 3810, 3862, 3889, 3945, 4005, 4071, 4108, 4127, 4189, 4222, 4243, 4275, 4294, 4352, 4415, 4440, 4463, 4484, 4508, 4538, 4574, 4627, 4665, 4709, 4752, 4783, 4810, 4857, 4897, 4943, 5018, 5076, 5137, 5186, 5228, 5274, 5312, 5351, 5390, 5436, 5475, 5526, 5577, 5689, 5802]}, {"subject_area"=>"/Biology and life sciences/Cell biology", "average_usage"=>[336, 898, 1202, 1349, 1463, 1567, 1688, 1812, 1925, 2038, 2149, 2233, 2308, 2394, 2437, 2517, 2573, 2610, 2670, 2730, 2776, 2795, 2872, 2909, 2987, 3049, 3085, 3132, 3194, 3233, 3289, 3354, 3385, 3419, 3444, 3468, 3499, 3534, 3566, 3605, 3659, 3709, 3764, 3798, 3844, 3905, 3960, 4025, 4072, 4120, 4160, 4192, 4236, 4282, 4311, 4367, 4395, 4431, 4477, 4520, 4573, 4637, 4700, 4733, 4769, 4811, 4848, 4883, 4918, 4954, 4994, 5052, 5092, 5121, 5160, 5190, 5229, 5301, 5375, 5432, 5482, 5525, 5572, 5610, 5653, 5696, 5735, 5774, 5810, 5846, 5891, 5940, 5978, 6062, 6149, 6214, 6264, 6302, 6348, 6434, 6518, 6653, 6732, 6851, 6900, 6977, 7047, 7090, 7157]}, {"subject_area"=>"/Biology and life sciences/Genetics", "average_usage"=>[390, 1051, 1336, 1575, 1746, 1880, 2002, 2089, 2183, 2259, 2395, 2486, 2567, 2650, 2735, 2821, 2880, 2946, 3020, 3083, 3136, 3189, 3252, 3274, 3320, 3361, 3399, 3437, 3477, 3517, 3580, 3630, 3692, 3747, 3801, 3847, 3872, 3896, 3954, 3995, 4023, 4046, 4070, 4143, 4270, 4326, 4388, 4446, 4485, 4563, 4617, 4686, 4731, 4770, 4820, 4865, 4920, 4990, 5065, 5133, 5197, 5262, 5314, 5364, 5400, 5431, 5473, 5511, 5545, 5570, 5605, 5627, 5663, 5713, 5743, 5757, 5788, 5840, 5948, 6033, 6057, 6086, 6107, 6145, 6183, 6252, 6306, 6348, 6383, 6417, 6456, 6488, 6519, 6572, 6731, 6791, 6873, 6947, 7008, 7062, 7112, 7211, 7283, 7314, 7356, 7486, 7644, 7716, 7760]}, {"subject_area"=>"/Biology and life sciences/Immunology", "average_usage"=>[318, 740, 952, 1102, 1195, 1295, 1389, 1512, 1657, 1730, 1848, 1929, 1966, 2027, 2081, 2119, 2164, 2200, 2243, 2308, 2376, 2420, 2458, 2491, 2521, 2574, 2616, 2668, 2717, 2765, 2815, 2851, 2886, 2917, 2959, 3087, 3125, 3172, 3234, 3282, 3334, 3396, 3434, 3470, 3504, 3576, 3641, 3698, 3747, 3800, 3849, 3903, 3934, 3980, 4005, 4023, 4060, 4088, 4107, 4132, 4160, 4189, 4240, 4284, 4330, 4353, 4377, 4403, 4422, 4440, 4458, 4535, 4600, 4671, 4728, 4750, 4790, 4843, 4905, 5133, 5174, 5218, 5284, 5322, 5378, 5430, 5496, 5531, 5576, 5639, 5714, 5754, 5798, 5842, 5870, 5902, 5957, 6008, 6061, 6109, 6161, 6218, 6272, 6322, 6362, 6417, 6476, 6532, 6591]}, {"subject_area"=>"/Medicine and health sciences", "average_usage"=>[332, 832, 1061, 1198, 1288, 1420, 1545, 1670, 1785, 1867, 1947, 2027, 2093, 2161, 2245, 2305, 2356, 2424, 2497, 2566, 2606, 2658, 2705, 2747, 2800, 2839, 2894, 2934, 2991, 3034, 3061, 3096, 3143, 3189, 3237, 3282, 3313, 3379, 3408, 3472, 3517, 3553, 3603, 3632, 3666, 3693, 3724, 3749, 3796, 3824, 3877, 3904, 3961, 4025, 4073, 4141, 4175, 4212, 4222, 4284, 4335, 4367, 4390, 4422, 4462, 4479, 4496, 4540, 4603, 4661, 4687, 4716, 4750, 4800, 4850, 4873, 4921, 4993, 5033, 5129, 5183, 5228, 5268, 5296, 5323, 5378, 5411, 5474, 5537, 5594, 5649, 5682, 5777, 5823, 5856, 5927, 6016, 6062, 6102, 6147, 6214, 6253, 6428, 6501, 6543, 6588, 6622, 6649, 6728]}, {"subject_area"=>"/Medicine and health sciences/Anatomy and physiology", "average_usage"=>[350, 850, 1104, 1261, 1420, 1515, 1598, 1675, 1720, 1823, 1923, 1989, 2045, 2109, 2234, 2265, 2300, 2343, 2438, 2497, 2551, 2604, 2652, 2710, 2755, 2782, 2810, 2837, 2864, 2891, 2958, 2979, 3000, 3103, 3170, 3244, 3283, 3314, 3346, 3377, 3418, 3484, 3533, 3607, 3636, 3660, 3681, 3708, 3747, 3784, 3810, 3862, 3889, 3945, 4005, 4071, 4108, 4127, 4189, 4222, 4243, 4275, 4294, 4352, 4415, 4440, 4463, 4484, 4508, 4538, 4574, 4627, 4665, 4709, 4752, 4783, 4810, 4857, 4897, 4943, 5018, 5076, 5137, 5186, 5228, 5274, 5312, 5351, 5390, 5436, 5475, 5526, 5577, 5689, 5802]}, {"subject_area"=>"/People and places", "average_usage"=>[380, 795, 983, 1102, 1199, 1297, 1390, 1478, 1618, 1693, 1747, 1794, 1851, 1903, 1949, 2009, 2036, 2085, 2138, 2196, 2248, 2291, 2336, 2345, 2371, 2392, 2412, 2439, 2475, 2509, 2558, 2612, 2684, 2736, 2810, 2850, 2884, 2936, 2988, 3036, 3087, 3124, 3171, 3212, 3268, 3323, 3364, 3418, 3471, 3517, 3583, 3637, 3687, 3716, 3780, 3836, 3873, 3919, 3981, 4016, 4050, 4090, 4110, 4128, 4153, 4189, 4238, 4274, 4295, 4321, 4378, 4416, 4440, 4468, 4498, 4555, 4628, 4693, 4745, 4779, 4829, 4863, 4883, 4905, 4942, 5003, 5045, 5092, 5142, 5184, 5245, 5287, 5331, 5410, 5467, 5514, 5542, 5592, 5629, 5669, 5715, 5774, 5818, 5872, 5939, 6010, 6067, 6107, 6131]}, {"subject_area"=>"/People and places/Population groupings", "average_usage"=>[404, 925, 1087, 1228, 1368, 1452, 1530, 1582, 1679, 1737, 1820, 1914, 1993, 2081, 2161, 2219, 2260, 2322, 2370, 2397, 2452, 2483, 2512, 2553, 2624, 2656, 2680, 2702, 2745, 2783, 2821, 2863, 2904, 2941, 2968, 2986, 3009, 3033, 3073, 3122, 3216, 3282, 3354, 3404, 3476, 3519, 3544, 3584, 3628, 3681, 3730, 3774, 3812, 3849, 3889, 3962, 4023, 4049, 4077, 4119, 4162, 4222, 4292, 4370, 4408, 4444, 4469, 4489, 4525, 4582, 4614, 4662, 4722, 4765, 4786, 4805, 4855, 4876, 4906, 4964, 5011, 5065, 5095, 5126, 5159, 5190, 5221, 5236, 5341, 5381, 5429, 5461, 5501, 5584, 5633, 5673, 5747, 5793, 5826, 5873, 5915, 6011, 6039, 6069, 6094, 6135, 6171, 6193, 6215]}]}

F1000Prime | Further Information

• {"year"=>2014, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-05-26T08:30:29Z"}
• {"year"=>2014, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-06-30T08:30:29Z"}
• {"year"=>2014, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-07-28T08:30:36Z"}
• {"year"=>2014, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-08-25T08:30:32Z"}
• {"year"=>2014, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-09-29T08:30:33Z"}
• {"year"=>2014, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-10-27T08:30:27Z"}
• {"year"=>2014, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-11-24T09:30:20Z"}
• {"year"=>2014, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2014-12-29T09:40:20Z"}
• {"year"=>2015, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-01-26T09:40:14Z"}
• {"year"=>2015, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-02-23T09:40:13Z"}
• {"year"=>2015, "month"=>3, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-03-23T08:40:14Z"}
• {"year"=>2015, "month"=>4, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-04-27T08:40:14Z"}
• {"year"=>2015, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-05-25T08:40:12Z"}
• {"year"=>2015, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-06-29T08:40:16Z"}
• {"year"=>2015, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-07-27T08:40:12Z"}
• {"year"=>2015, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-08-31T08:40:14Z"}
• {"year"=>2015, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-09-28T08:40:16Z"}
• {"year"=>2015, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-10-26T08:40:15Z"}
• {"year"=>2015, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-11-30T09:40:14Z"}
• {"year"=>2015, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2015-12-28T09:40:15Z"}
• {"year"=>2016, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-01-25T09:40:15Z"}
• {"year"=>2016, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-02-29T09:40:11Z"}
• {"year"=>2016, "month"=>3, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-03-28T08:40:11Z"}
• {"year"=>2016, "month"=>4, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-04-25T08:40:11Z"}
• {"year"=>2016, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-05-16T08:40:12Z"}
• {"year"=>2016, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-06-27T08:40:12Z"}
• {"year"=>2016, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-07-25T08:40:14Z"}
• {"year"=>2016, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-08-29T08:40:11Z"}
• {"year"=>2016, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-09-26T08:40:15Z"}
• {"year"=>2016, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-10-31T08:40:11Z"}
• {"year"=>2016, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-11-28T09:40:12Z"}
• {"year"=>2016, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2016-12-26T09:40:13Z"}
• {"year"=>2017, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-01-30T09:40:11Z"}
• {"year"=>2017, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-02-27T09:40:13Z"}
• {"year"=>2017, "month"=>3, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-03-27T08:40:10Z"}
• {"year"=>2017, "month"=>4, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-04-24T08:40:08Z"}
• {"year"=>2017, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-05-29T08:40:09Z"}
• {"year"=>2017, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"http://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-06-26T08:40:08Z"}
• {"year"=>2017, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-07-31T08:40:13Z"}
• {"year"=>2017, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-08-28T08:40:08Z"}
• {"year"=>2017, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-09-25T08:40:10Z"}
• {"year"=>2017, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-10-30T08:40:16Z"}
• {"year"=>2017, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-11-27T09:40:17Z"}
• {"year"=>2017, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2017-12-25T09:40:08Z"}
• {"year"=>2018, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-01-29T09:40:08Z"}
• {"year"=>2018, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-02-26T09:40:09Z"}
• {"year"=>2018, "month"=>3, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-03-26T08:40:08Z"}
• {"year"=>2018, "month"=>4, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-04-30T08:40:08Z"}
• {"year"=>2018, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-05-28T08:40:10Z"}
• {"year"=>2018, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-06-25T08:40:09Z"}
• {"year"=>2018, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-07-30T08:40:10Z"}
• {"year"=>2018, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-08-27T08:40:09Z"}
• {"year"=>2018, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-09-24T08:40:09Z"}
• {"year"=>2018, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-10-29T08:40:09Z"}
• {"year"=>2018, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-11-26T09:40:10Z"}
• {"year"=>2018, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2018-12-31T09:40:10Z"}
• {"year"=>2019, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-01-28T09:40:10Z"}
• {"year"=>2019, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-02-25T09:40:13Z"}
• {"year"=>2019, "month"=>3, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-03-25T08:40:08Z"}
• {"year"=>2019, "month"=>4, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-04-29T08:40:11Z"}
• {"year"=>2019, "month"=>5, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-05-27T08:40:14Z"}
• {"year"=>2019, "month"=>6, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-06-24T08:40:10Z"}
• {"year"=>2019, "month"=>7, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-07-29T08:40:10Z"}
• {"year"=>2019, "month"=>8, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-08-26T08:40:12Z"}
• {"year"=>2019, "month"=>9, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-09-30T08:40:09Z"}
• {"year"=>2019, "month"=>10, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-10-28T08:40:11Z"}
• {"year"=>2019, "month"=>11, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-11-25T09:40:14Z"}
• {"year"=>2019, "month"=>12, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2019-12-30T09:40:11Z"}
• {"year"=>2020, "month"=>1, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2020-01-27T09:40:10Z"}
• {"year"=>2020, "month"=>2, "doi"=>"10.1371/journal.pmed.0020343", "f1000_id"=>"1029057", "url"=>"https://f1000.com/prime/1029057", "score"=>1, "classifications"=>["new_finding"], "updated_at"=>"2020-02-17T09:40:08Z"}