OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice
- Publication Date
- November 28, 2006
- Journal
- PLOS Medicine
- Authors
- Makoto Matsumoto, Hiroyuki Hashizume, Tatsuo Tomishige, Masanori Kawasaki, et al
- Volume
- 3
- Issue
- 11
- Pages
- e466
- DOI
- https://dx.plos.org/10.1371/journal.pmed.0030466
- Publisher URL
- http://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.0030466
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/17132069
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664607
- Europe PMC
- http://europepmc.org/abstract/MED/17132069
- Web of Science
- 000242374800018
- Scopus
- 33845323336
- Mendeley
- http://www.mendeley.com/research/opc67683-nitrodihydroimidazooxazole-derivative-promising-action-against-tuberculosis-vitro-mice
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Mendeley | Further Information
{"title"=>"OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice", "type"=>"journal", "authors"=>[{"first_name"=>"Makoto", "last_name"=>"Matsumoto", "scopus_author_id"=>"7404940293"}, {"first_name"=>"Hiroyuki", "last_name"=>"Hashizume", "scopus_author_id"=>"36658143800"}, {"first_name"=>"Tatsuo", "last_name"=>"Tomishige", "scopus_author_id"=>"16069778000"}, {"first_name"=>"Masanori", "last_name"=>"Kawasaki", "scopus_author_id"=>"36811538400"}, {"first_name"=>"Hidetsugu", "last_name"=>"Tsubouchi", "scopus_author_id"=>"15756145800"}, {"first_name"=>"Hirofumi", "last_name"=>"Sasaki", "scopus_author_id"=>"36770893300"}, {"first_name"=>"Yoshihiko", "last_name"=>"Shimokawa", "scopus_author_id"=>"7006659141"}, {"first_name"=>"Makoto", "last_name"=>"Komatsu", "scopus_author_id"=>"7202792608"}], "year"=>2006, "source"=>"PLoS Medicine", "identifiers"=>{"pmid"=>"17132069", "doi"=>"10.1371/journal.pmed.0030466", "sgr"=>"33845323336", "isbn"=>"1549-1676 (Electronic)", "scopus"=>"2-s2.0-33845323336", "issn"=>"15491277", "pui"=>"44875946"}, "id"=>"5bc8179b-2cf6-3d34-8f42-616fe84c4825", "abstract"=>"BACKGROUND Tuberculosis (TB) is still a leading cause of death worldwide. Almost a third of the world's population is infected with TB bacilli, and each year approximately 8 million people develop active TB and 2 million die as a result. Today's TB treatment, which dates back to the 1970s, is long and burdensome, requiring at least 6 mo of multidrug chemotherapy. The situation is further compounded by the emergence of multidrug-resistant TB (MDR-TB) and by the infection's lethal synergy with HIV/AIDS. Global health and philanthropic organizations are now pleading for new drug interventions that can address these unmet needs in TB treatment. METHODS AND FINDINGS Here we report OPC-67683, a nitro-dihydro-imidazooxazole derivative that was screened to help combat the unmet needs in TB treatment. The compound is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against TB, including MDR-TB, as shown by its exceptionally low minimum inhibitory concentration (MIC) range of 0.006-0.024 microg/ml in vitro and highly effective therapeutic activity at low doses in vivo. Additionally, the results of the post-antibiotic effect of OPC-67683 on intracellular Mycobacterium tuberculosis showed the agent to be highly and dose-dependently active also against intracellular M. tuberculosis H37Rv after a 4-h pulsed exposure, and this activity at a concentration of 0.1 microg/ml was similar to that of the first-line drug rifampicin (RFP) at a concentration of 3 microg/ml. The combination of OPC-67683 with RFP and pyrazinamide (PZA) exhibited a remarkably quicker eradication (by at least 2 mo) of viable TB bacilli in the lung in comparison with the standard regimen consisting of RFP, isoniazid (INH), ethambutol (EB), and PZA. Furthermore, OPC-67683 was not affected by nor did it affect the activity of liver microsome enzymes, suggesting the possibility for OPC-67683 to be used in combination with drugs, including anti-retrovirals, that induce or are metabolized by cytochrome P450 enzymes. CONCLUSIONS We concluded that based on these properties OPC-67683 has the potential to be used as a TB drug to help combat the unmet needs in TB treatment.", "link"=>"http://www.mendeley.com/research/opc67683-nitrodihydroimidazooxazole-derivative-promising-action-against-tuberculosis-vitro-mice", "reader_count"=>193, "reader_count_by_academic_status"=>{"Unspecified"=>8, "Professor > Associate Professor"=>8, "Researcher"=>32, "Student > Doctoral Student"=>10, "Student > Ph. D. Student"=>48, "Student > Postgraduate"=>5, "Student > Master"=>26, "Other"=>15, "Student > Bachelor"=>25, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>3, "Professor"=>11}, "reader_count_by_user_role"=>{"Unspecified"=>8, "Professor > Associate Professor"=>8, "Researcher"=>32, "Student > Doctoral Student"=>10, "Student > Ph. D. Student"=>48, "Student > Postgraduate"=>5, "Student > Master"=>26, "Other"=>15, "Student > Bachelor"=>25, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>3, "Professor"=>11}, "reader_count_by_subject_area"=>{"Unspecified"=>13, "Biochemistry, Genetics and Molecular Biology"=>16, "Agricultural and Biological Sciences"=>64, "Medicine and Dentistry"=>43, "Pharmacology, Toxicology and Pharmaceutical Science"=>7, "Business, Management and Accounting"=>1, "Physics and Astronomy"=>1, "Chemistry"=>36, "Social Sciences"=>2, "Immunology and Microbiology"=>9, "Earth and Planetary Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>43}, "Chemistry"=>{"Chemistry"=>36}, "Social Sciences"=>{"Social Sciences"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>9}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>64}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>16}, "Unspecified"=>{"Unspecified"=>13}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>7}}, "reader_count_by_country"=>{"Netherlands"=>1, "Sweden"=>1, "Argentina"=>1, "United States"=>1, "Japan"=>2, "United Kingdom"=>1, "Spain"=>1, "Russia"=>1, "India"=>2}, "group_count"=>5}CrossRef
- http://doi.org/10.3390/ijms20122868
- http://doi.org/10.1016/S0213-005X(11)70018-0
- http://doi.org/10.4068/cmj.2017.53.2.103
- http://doi.org/10.1016/j.tube.2017.12.002
- http://doi.org/10.1016/j.antib.2009.01.003
- http://doi.org/10.1016/j.ejmech.2017.02.058
- http://doi.org/10.1007/s40265-014-0331-4
- http://doi.org/10.1039/C9NJ03462E
- http://doi.org/10.1002/bdd.2064
- http://doi.org/10.1016/j.tube.2018.10.009
- http://doi.org/10.4155/fmc.15.128
- http://doi.org/10.1016/j.poly.2010.07.017
- http://doi.org/10.1016/j.addr.2016.04.026
- http://doi.org/10.3390/molecules22122142
- http://doi.org/10.1371/journal.pmed.1001965
- http://doi.org/10.1517/21678707.2014.863729
- http://doi.org/10.12688/f1000research.7403.1
- http://doi.org/10.1111/resp.13393
- http://doi.org/10.1038/nm0307-276
- http://doi.org/10.1002/med.21602
- http://doi.org/10.1126/scitranslmed.3007355
- http://doi.org/10.1186/s13073-019-0660-8
- http://doi.org/10.1016/j.ejmech.2019.02.010
- http://doi.org/10.1016/j.tips.2008.08.001
- http://doi.org/10.1002/emmm.201303575
- http://doi.org/10.1164/rccm.200807-1152OC
- http://doi.org/10.1039/C7MD00350A
- http://doi.org/10.1038/nrmicro1816
- http://doi.org/10.1164/rccm.200904-0536OC
- http://doi.org/10.1098/rstb.2015.0506
- http://doi.org/10.1016/j.tim.2013.05.002
- http://doi.org/10.1111/j.1440-1843.2010.01775.x
- http://doi.org/10.1016/j.rmed.2009.07.010
- http://doi.org/10.1097/MJT.0b013e3181c3509c
- http://doi.org/10.1007/s00253-015-6502-8
- http://doi.org/10.2217/fmb-2017-0054
- http://doi.org/10.1186/1465-9921-11-169
- http://doi.org/10.1177/1753465812452193
- http://doi.org/10.1038/nm0307-279
- http://doi.org/10.1016/j.ijtb.2017.03.002
- http://doi.org/10.1038/s41586-019-1315-z
- http://doi.org/10.1126/science.aag1006
- http://doi.org/10.1093/infdis/jis191
- http://doi.org/10.1016/j.drudis.2017.05.005
- http://doi.org/10.1074/jbc.M114.581579
- http://doi.org/10.1021/acs.chemrev.7b00602
- http://doi.org/10.1093/jac/dkr173
- http://doi.org/10.1093/mutage/ges015
- http://doi.org/10.1517/14656566.2015.973853
- http://doi.org/10.1021/jm1010644
- http://doi.org/10.4161/cib.2.3.7926
- http://doi.org/10.1074/jbc.M114.582445
- http://doi.org/10.1016/j.lpm.2017.01.016
- http://doi.org/10.1128/AAC.00509-16
- http://doi.org/10.1517/14728214.2011.521497
- http://doi.org/10.3109/23744235.2015.1061205
- http://doi.org/10.1016/j.biopha.2018.04.176
- http://doi.org/10.1128/JB.01035-15
- http://doi.org/10.1021/jm4012774
- http://doi.org/10.1016/j.bmc.2015.10.029
- http://doi.org/10.1039/C9OB00817A
- http://doi.org/10.1093/cid/ciz235
- http://doi.org/10.1186/s13065-018-0441-2
- http://doi.org/10.1021/jm501608q
- http://doi.org/10.1021/acsomega.7b01740
- http://doi.org/10.1016/j.mib.2011.07.022
- http://doi.org/10.1007/s00108-015-0011-9
- http://doi.org/10.1080/1120009X.2017.1338845
- http://doi.org/10.1248/bpb.b14-00311
- http://doi.org/10.1038/srep29717
- http://doi.org/10.1016/j.tube.2018.04.008
- http://doi.org/10.1021/acs.jmedchem.8b01578
- http://doi.org/10.1183/09031936.00162314
- http://doi.org/10.1016/j.prrv.2007.04.001
- http://doi.org/10.1128/AAC.05293-11
- http://doi.org/10.1586/17476348.2.4.455
- http://doi.org/10.4155/fmc.09.53
- http://doi.org/10.1021/jm200377r
- http://doi.org/10.20965/jdr.2011.p0443
- http://doi.org/10.1128/AAC.03049-15
- http://doi.org/10.1080/09168451.2016.1248369
- http://doi.org/10.1183/13993003.01420-2016
- http://doi.org/10.1517/14656566.2012.657176
- http://doi.org/10.2217/fmb.13.85
- http://doi.org/10.1016/j.bioorg.2018.08.025
- http://doi.org/10.1039/C9MD00057G
- http://doi.org/10.1016/j.str.2011.11.001
- http://doi.org/10.1371/journal.pone.0028428
- http://doi.org/10.1016/j.ejmech.2011.01.071
- http://doi.org/10.1002/cmdc.201000526
- http://doi.org/10.1021/jm300123s
- http://doi.org/10.7554/eLife.09744
- http://doi.org/10.1016/j.ejmech.2016.09.082
- http://doi.org/10.1093/jac/dkm291
- http://doi.org/10.1002/cmdc.201300209
- http://doi.org/10.1186/s13063-018-3053-1
- http://doi.org/10.2217/fmb.09.20
- http://doi.org/10.1097/MCP.0000000000000045
- http://doi.org/10.1016/j.tube.2019.05.002
- http://doi.org/10.1097/CPM.0b013e3181940865
- http://doi.org/10.1016/j.healthplace.2011.05.004
- http://doi.org/10.1080/17425255.2016.1183643
- http://doi.org/10.3390/ph11020054
- http://doi.org/10.1016/j.jchromb.2015.07.058
- http://doi.org/10.3389/fcimb.2018.00114
- http://doi.org/10.1039/C4MD00301B
- http://doi.org/10.1016/j.yrtph.2018.02.011
- http://doi.org/10.1016/S0761-8425(08)56012-8
- http://doi.org/10.1002/ardp.201800277
- http://doi.org/10.1038/ja.2011.44
- http://doi.org/10.2174/0929867325666180426164352
- http://doi.org/10.1038/s41598-017-09177-2
- http://doi.org/10.1074/jbc.RA119.010135
- http://doi.org/10.3989/alqantara.2016.003
- http://doi.org/10.1517/13543776.17.6.617
- http://doi.org/10.1002/med.21262
- http://doi.org/10.1021/acsinfecdis.6b00150
- http://doi.org/10.1007/s12275-017-6630-1
- http://doi.org/10.1038/ncomms5989
- http://doi.org/10.1128/AAC.02402-16
- http://doi.org/10.1016/j.tube.2013.02.010
- http://doi.org/10.1016/j.ejps.2018.05.024
- http://doi.org/10.1134/S1022795411120118
- http://doi.org/10.1016/j.meegid.2018.09.023
- http://doi.org/10.1371/journal.pone.0012451
- http://doi.org/10.1038/nchembio.2420
- http://doi.org/10.1016/j.cmrp.2014.09.005
- http://doi.org/10.1016/j.coph.2012.07.004
- http://doi.org/10.1016/j.ccm.2009.08.011
- http://doi.org/10.1128/AAC.03014-15
- http://doi.org/10.1016/j.meegid.2018.10.003
- http://doi.org/10.1074/jbc.RA117.000760
- http://doi.org/10.1038/s41586-018-0327-4
- http://doi.org/10.1128/AAC.00614-15
- http://doi.org/10.1124/dmd.115.064550
- http://doi.org/10.1021/acs.jmedchem.7b00631
- http://doi.org/10.1016/j.bmc.2008.07.070
- http://doi.org/10.4137/CMT.S11675
- http://doi.org/10.1586/ecp.09.19
- http://doi.org/10.1016/j.ccm.2019.08.001
- http://doi.org/10.1164/rccm.200904-0611OC
- http://doi.org/10.1016/j.tube.2017.12.006
- http://doi.org/10.1002/iub.1863
- http://doi.org/10.1007/s00706-011-0542-2
- http://doi.org/10.1093/bmb/ldu011
- http://doi.org/10.1007/s40265-014-0241-5
- http://doi.org/10.1016/S1472-9792(08)70032-5
- http://doi.org/10.1073/pnas.0800663105
- http://doi.org/10.1007/s00044-012-0348-8
- http://doi.org/10.1038/srep13985
- http://doi.org/10.1093/cid/civ609
- http://doi.org/10.5059/yukigoseikyokaishi.72.1239
- http://doi.org/10.1016/j.ejps.2017.05.053
- http://doi.org/10.1016/S1473-3099(08)70260-3
- http://doi.org/10.1002/cmdc.201500462
- http://doi.org/10.1111/cbdd.13624
- http://doi.org/10.1371/journal.pone.0087909
- http://doi.org/10.1021/acs.jmedchem.6b01718
- http://doi.org/10.21292/2075-1230-2018-96-11-74-82
- http://doi.org/10.1111/mmi.12127
- http://doi.org/10.1042/BST0351321
- http://doi.org/10.1124/dmd.115.064527
- http://doi.org/10.3950/jibiinkoka.115.141
- http://doi.org/10.1128/MMBR.00070-15
- http://doi.org/10.3389/fmolb.2017.00075
- http://doi.org/10.1016/j.coph.2018.06.006
- http://doi.org/10.1016/j.drudis.2008.09.004
- http://doi.org/10.1111/cbdd.13386
- http://doi.org/10.1007/s10405-013-0696-1
- http://doi.org/10.1016/j.phymed.2018.04.029
- http://doi.org/10.1002/jcp.22419
- http://doi.org/10.1002/14651858.CD012918
- http://doi.org/10.1128/AAC.00969-17
- http://doi.org/10.1016/j.chemolab.2013.09.011
- http://doi.org/10.1016/j.ejmech.2014.05.069
- http://doi.org/10.3389/fmicb.2015.00812
- http://doi.org/10.3389/fmicb.2018.02960
- http://doi.org/10.2478/s11532-012-0087-1
- http://doi.org/10.1016/j.ejmech.2012.02.033
- http://doi.org/10.1371/journal.pone.0215607
- http://doi.org/10.2174/1389201019666180731120544
- http://doi.org/10.1016/j.ejmech.2016.11.041
- http://doi.org/10.1016/j.medmal.2016.07.006
- http://doi.org/10.1016/j.medcli.2013.01.039
- http://doi.org/10.1016/j.chembiol.2019.10.010
- http://doi.org/10.1080/03602532.2016.1195404
- http://doi.org/10.1007/s10405-013-0745-9
- http://doi.org/10.1038/nrdp.2016.76
- http://doi.org/10.4155/fmc.10.207
- http://doi.org/10.1172/JCI34614
- http://doi.org/10.1016/S1472-9792(08)70017-9
- http://doi.org/10.1016/j.bmcl.2016.11.084
- http://doi.org/10.1016/j.bmcl.2015.02.061
- http://doi.org/10.3390/ph3072268
- http://doi.org/10.1517/14656560802694564
- http://doi.org/10.1038/ja.2013.86
- http://doi.org/10.1371/journal.pone.0096348
- http://doi.org/10.1038/nm0307-280
- http://doi.org/10.1097/QAI.0b013e31821b4b42
- http://doi.org/10.1016/j.drudis.2007.08.001
- http://doi.org/10.15406/japlr.2017.05.00161
- http://doi.org/10.1517/14656566.2015.1100169
- http://doi.org/10.1007/s00253-016-8038-y
- http://doi.org/10.1590/1414-431x20176188
- http://doi.org/10.1128/AAC.00665-19
- http://doi.org/10.1128/AAC.03822-14
- http://doi.org/10.1038/sj.clpt.6100362
- http://doi.org/10.1016/j.jgg.2016.10.002
- http://doi.org/10.1038/ja.2017.126
- http://doi.org/10.1016/j.ejmech.2013.06.042
- http://doi.org/10.1016/j.bmc.2008.05.061
- http://doi.org/10.1183/09031936.00147014
- http://doi.org/10.1128/mBio.01910-17
- http://doi.org/10.1093/jac/dkw044
- http://doi.org/10.1517/17460441.3.1.21
- http://doi.org/10.4155/fmc.10.215
- http://doi.org/10.1093/trstmh/trv107
- http://doi.org/10.1016/j.bmcl.2008.03.011
- http://doi.org/10.1021/jm200305q
- http://doi.org/10.1016/j.bmcl.2010.08.127
- http://doi.org/10.1016/j.tube.2015.11.009
- http://doi.org/10.1021/acs.biochem.6b00638
- http://doi.org/10.1021/ml5003458
- http://doi.org/10.1128/mBio.00301-10
- http://doi.org/10.1021/acsinfecdis.7b00255
- http://doi.org/10.1007/s12272-015-0645-0
- http://doi.org/10.1038/nrd4001
- http://doi.org/10.1093/jac/dkn307
- http://doi.org/10.1128/AAC.00913-19
- http://doi.org/10.1007/s40267-015-0251-8
- http://doi.org/10.1056/NEJMoa1112433
- http://doi.org/10.1586/14787210.2015.1011127
- http://doi.org/10.1021/acs.jmedchem.5b01699
- http://doi.org/10.1517/13543776.2013.749862
- http://doi.org/10.1021/acs.jmedchem.7b00143
- http://doi.org/10.1586/14760584.7.4.481
- http://doi.org/10.1080/13543776.2017.1253681
- http://doi.org/10.1177/1753465808099522
- http://doi.org/10.3389/fmicb.2017.00681
- http://doi.org/10.1111/j.1440-1843.2008.01342.x
- http://doi.org/10.1016/j.ijantimicag.2018.02.022
- http://doi.org/10.1128/AAC.00136-19
- http://doi.org/10.1016/S2213-2600(17)30078-4
- http://doi.org/10.1128/CMR.00033-13
- http://doi.org/10.1371/journal.pone.0012843
- http://doi.org/10.2217/fmb.11.46
- http://doi.org/10.3390/pharmaceutics11070352
- http://doi.org/10.1016/j.antinf.2013.06.001
- http://doi.org/10.1021/acs.jmedchem.9b00912
- http://doi.org/10.1074/jbc.RA118.005732
- http://doi.org/10.1007/s12275-018-7414-y
- http://doi.org/10.1371/journal.pone.0087483
- http://doi.org/10.1586/eri.12.91
- http://doi.org/10.1128/AAC.02632-12
- http://doi.org/10.1016/j.mencom.2018.07.017
- http://doi.org/10.1016/j.drudis.2016.09.010
- http://doi.org/10.3343/alm.2018.38.6.563
- http://doi.org/10.1517/14656566.2015.1080240
- http://doi.org/10.1164/rccm.201502-0372LE
- http://doi.org/10.1038/ja.2016.72
- http://doi.org/10.1016/j.biopha.2017.09.036
- http://doi.org/10.1038/s41467-017-00419-5
- http://doi.org/10.1371/journal.pntd.0000923
- http://doi.org/10.1183/13993003.01105-2017
- http://doi.org/10.1513/AnnalsATS.201509-632PS
- http://doi.org/10.1016/j.yrtph.2016.12.002
- http://doi.org/10.1126/science.1171583
- http://doi.org/10.1002/cmdc.201000169
- http://doi.org/10.1021/acs.jmedchem.8b00147
- http://doi.org/10.1128/AAC.00384-12
- http://doi.org/10.1126/science.1164571
- http://doi.org/10.1016/j.pbiomolbio.2019.11.002
- http://doi.org/10.1586/ers.09.15
- http://doi.org/10.1111/j.1742-4658.2011.08404.x
- http://doi.org/10.4155/fmc.11.90
- http://doi.org/10.1039/C9SC00415G
- http://doi.org/10.1002/cmdc.201700424
- http://doi.org/10.1016/j.bmc.2015.10.021
- http://doi.org/10.1111/resp.13345
- http://doi.org/10.1620/tjem.221.97
- http://doi.org/10.1128/AAC.00849-10
- http://doi.org/10.1097/COH.0000000000000009
- http://doi.org/10.1371/journal.pone.0138436
- http://doi.org/10.1016/j.biopha.2018.01.115
- http://doi.org/10.1021/jm400381v
- http://doi.org/10.1039/b801859f
- http://doi.org/10.1002/psc.3213
- http://doi.org/10.1080/14656566.2016.1215428
- http://doi.org/10.1016/S0140-6736(10)60359-9
- http://doi.org/10.1021/acsinfecdis.9b00295
- http://doi.org/10.1128/AAC.05500-11
- http://doi.org/10.1111/j.1440-1843.2007.01180.x
- http://doi.org/10.1016/j.antinf.2015.07.003
- http://doi.org/10.1093/infdis/jis034
- http://doi.org/10.1517/13543784.2016.1121993
- http://doi.org/10.2165/11538170-000000000-00000
- http://doi.org/10.1021/ci800143n
- http://doi.org/10.1586/eri.10.60
- http://doi.org/10.1093/jac/dkw467
- http://doi.org/10.1016/j.ejmech.2019.06.068
- http://doi.org/10.1016/j.biopha.2017.04.105
- http://doi.org/10.1016/j.tube.2010.09.001
- http://doi.org/10.4155/fmc.11.115
- http://doi.org/10.1038/ncomms3748
- http://doi.org/10.1021/acscatal.9b01506
- http://doi.org/10.3389/fmicb.2018.01367
- http://doi.org/10.1016/j.bmc.2013.08.048
- http://doi.org/10.1016/j.ejmech.2014.08.066
- http://doi.org/10.1111/j.1440-1843.2012.02257.x
- http://doi.org/10.1039/c3md00366c
- http://doi.org/10.1016/S1472-9792(08)70037-4
- http://doi.org/10.4236/ajac.2015.62009
- http://doi.org/10.1039/B915877D
- http://doi.org/10.1021/jm2012276
- http://doi.org/10.1007/s11095-011-0413-x
- http://doi.org/10.1128/AAC.00996-19
- http://doi.org/10.1016/j.carres.2011.05.034
- http://doi.org/10.1517/17460441.2011.586999
- http://doi.org/10.1016/j.jgar.2019.06.013
- http://doi.org/10.1128/AAC.00441-19
- http://doi.org/10.1016/j.pupt.2016.06.009
- http://doi.org/10.1128/AAC.03823-14
- http://doi.org/10.1021/acs.chemrev.5b00392
- http://doi.org/10.1002/cmdc.201800755
- http://doi.org/10.1016/j.bmcl.2018.12.053
- http://doi.org/10.1074/jbc.M113.494781
- http://doi.org/10.1517/13543784.2012.724397
- http://doi.org/10.1016/j.bmc.2017.02.003
- http://doi.org/10.1016/j.drudis.2016.09.006
- http://doi.org/10.1016/j.jpba.2016.02.027
- http://doi.org/10.4137/CMT.S18560
- http://doi.org/10.1371/journal.pone.0087834
- http://doi.org/10.3390/molecules24061026
- http://doi.org/10.1128/AAC.01459-13
- http://doi.org/10.1021/acs.jmedchem.7b00034
- http://doi.org/10.1039/C5OB00054H
- http://doi.org/10.1093/infdis/jir858
- http://doi.org/10.1371/journal.pone.0105222
- http://doi.org/10.1021/acsmedchemlett.5b00202
- http://doi.org/10.3390/molecules24102021
- http://doi.org/10.3390/antibiotics3030317
- http://doi.org/10.1016/j.rmedc.2010.08.001
- http://doi.org/10.1111/joim.12264
- http://doi.org/10.1128/AAC.03085-15
- http://doi.org/10.1038/s41429-019-0205-9
- http://doi.org/10.1002/emmm.201201772
- http://doi.org/10.1038/nri.2017.69
- http://doi.org/10.1093/cid/ciz074
- http://doi.org/10.1183/23120541.00010-2015
Europe PMC Database Citations | Further Information
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- 3004849
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- 2415778
- 2565869
- 2650526
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- 3019674
- 3370712
- 3421551
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- 3910739
- 3993272
- 4291340
- 4291341
- 4468675
- 3232757
- 3232786
- 3811234
- 2276805
- 2517617
- 4775029
- 2408714
- 2596992
- 2674232
- 2723733
- 2765540
- 2834421
- 3125433
- 3158291
- 3225966
- 3395780
- 3571691
- 3647464
- 3816974
- 3839627
- 2918717
- 3002907
- 4049535
- 4182730
- 4237170
- 4461445
- 3444742
- 3567243
- 3128490
- 3968807
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- 4008622
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- 4580611
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- 2742745
- 3006138
- 3789948
- 4155670
- 4155671
- 2566515
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- 3439222
- 4319680
- 4007262
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- 3719028
- 4523840
- 4568539
- 4598488
- 3262386
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- 3958311
- 3669462
- 3002907
- 4755422
- 4329575
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Scopus | Further Information
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- {"month"=>"2", "year"=>"2017", "pdf_views"=>"68", "xml_views"=>"1", "html_views"=>"88"}
- {"month"=>"3", "year"=>"2017", "pdf_views"=>"55", "xml_views"=>"0", "html_views"=>"140"}
- {"month"=>"4", "year"=>"2017", "pdf_views"=>"60", "xml_views"=>"0", "html_views"=>"133"}
- {"month"=>"5", "year"=>"2017", "pdf_views"=>"51", "xml_views"=>"2", "html_views"=>"114"}
- {"month"=>"6", "year"=>"2017", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"85"}
- {"month"=>"7", "year"=>"2017", "pdf_views"=>"60", "xml_views"=>"1", "html_views"=>"117"}
- {"month"=>"8", "year"=>"2017", "pdf_views"=>"67", "xml_views"=>"1", "html_views"=>"97"}
- {"month"=>"9", "year"=>"2017", "pdf_views"=>"44", "xml_views"=>"2", "html_views"=>"92"}
- {"month"=>"10", "year"=>"2017", "pdf_views"=>"47", "xml_views"=>"1", "html_views"=>"98"}
- {"month"=>"11", "year"=>"2017", "pdf_views"=>"35", "xml_views"=>"2", "html_views"=>"102"}
- {"month"=>"12", "year"=>"2017", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"59"}
- {"month"=>"1", "year"=>"2018", "pdf_views"=>"31", "xml_views"=>"1", "html_views"=>"81"}
- {"month"=>"2", "year"=>"2018", "pdf_views"=>"35", "xml_views"=>"1", "html_views"=>"60"}
- {"month"=>"3", "year"=>"2018", "pdf_views"=>"45", "xml_views"=>"1", "html_views"=>"111"}
- {"month"=>"4", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"2", "html_views"=>"48"}
- {"month"=>"5", "year"=>"2018", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"31"}
- {"month"=>"6", "year"=>"2018", "pdf_views"=>"37", "xml_views"=>"3", "html_views"=>"64"}
- {"month"=>"7", "year"=>"2018", "pdf_views"=>"25", "xml_views"=>"6", "html_views"=>"36"}
- {"month"=>"8", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"4", "html_views"=>"38"}
- {"month"=>"9", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"1", "html_views"=>"46"}
- {"month"=>"10", "year"=>"2018", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"41"}
- {"month"=>"11", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"38"}
- {"month"=>"12", "year"=>"2018", "pdf_views"=>"16", "xml_views"=>"3", "html_views"=>"30"}
- {"month"=>"1", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"31"}
- {"month"=>"2", "year"=>"2019", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"30"}
- {"month"=>"3", "year"=>"2019", "pdf_views"=>"30", "xml_views"=>"2", "html_views"=>"25"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"35", "xml_views"=>"3", "html_views"=>"32"}
- {"month"=>"5", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"2", "html_views"=>"43"}
- {"month"=>"6", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"35"}
- {"month"=>"7", "year"=>"2019", "pdf_views"=>"50", "xml_views"=>"1", "html_views"=>"29"}
- {"month"=>"8", "year"=>"2019", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"35"}
- {"month"=>"9", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"3", "html_views"=>"21"}
- {"month"=>"10", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"32"}
- {"month"=>"11", "year"=>"2019", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"32"}
- {"month"=>"12", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"3", "html_views"=>"6"}
PMC Usage Stats | Further Information
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- {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"15", "unique-ip"=>"16", "pdf"=>"9", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"16", "year"=>"2010", "pdf"=>"10", "unique-ip"=>"20", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"36", "unique-ip"=>"33", "pdf"=>"18", "year"=>"2010", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"19", "year"=>"2010", "pdf"=>"19", "unique-ip"=>"22", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "unique-ip"=>"24", "pdf"=>"20", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"13", "year"=>"2010", "pdf"=>"14", "unique-ip"=>"18", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"1", "abstract"=>"3", "full-text"=>"49", "unique-ip"=>"24", "pdf"=>"10", "year"=>"2010", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"27", "year"=>"2010", "pdf"=>"11", "unique-ip"=>"30", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"25", "unique-ip"=>"24", "pdf"=>"9", "year"=>"2010", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"40", "year"=>"2010", "pdf"=>"16", "unique-ip"=>"33", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"37", "unique-ip"=>"36", "pdf"=>"12", "year"=>"2011", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"4", "abstract"=>"3", "full-text"=>"41", "year"=>"2011", "pdf"=>"20", "unique-ip"=>"34", "figure"=>"18", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"36", "unique-ip"=>"35", "pdf"=>"7", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"30", "year"=>"2011", "pdf"=>"14", "unique-ip"=>"29", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"22", "unique-ip"=>"28", "pdf"=>"6", "year"=>"2011", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"16", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"25", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"21", "unique-ip"=>"22", "pdf"=>"13", "year"=>"2011", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"28", "year"=>"2011", "pdf"=>"16", "unique-ip"=>"29", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"24", "unique-ip"=>"23", "pdf"=>"17", "year"=>"2011", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"15", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"17", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "unique-ip"=>"20", "pdf"=>"13", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"9", "year"=>"2011", "pdf"=>"2", "unique-ip"=>"10", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "year"=>"2012", "pdf"=>"4", "unique-ip"=>"17", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"23", "unique-ip"=>"19", "pdf"=>"6", "year"=>"2012", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "year"=>"2012", "pdf"=>"11", "unique-ip"=>"16", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "unique-ip"=>"16", "pdf"=>"9", "year"=>"2012", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "year"=>"2012", "pdf"=>"7", "unique-ip"=>"18", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"36", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"8", "pdf"=>"1", "year"=>"2006", "figure"=>"97", "scanned-summary"=>"51", "supp-data"=>"51"}
- {"month"=>"1", "scanned-page-browse"=>"34", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2007", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"108", "scanned-summary"=>"68", "supp-data"=>"61"}
- {"scanned-page-browse"=>"33", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"8", "pdf"=>"0", "year"=>"2007", "figure"=>"97", "scanned-summary"=>"56", "supp-data"=>"52"}
- {"month"=>"3", "scanned-page-browse"=>"52", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2007", "pdf"=>"3", "unique-ip"=>"2", "figure"=>"135", "scanned-summary"=>"78", "supp-data"=>"71"}
- {"scanned-page-browse"=>"42", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"22", "pdf"=>"1", "year"=>"2007", "figure"=>"145", "scanned-summary"=>"75", "supp-data"=>"83"}
- {"month"=>"5", "scanned-page-browse"=>"32", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2007", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"103", "scanned-summary"=>"67", "supp-data"=>"50"}
- {"scanned-page-browse"=>"42", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"5", "pdf"=>"0", "year"=>"2007", "figure"=>"93", "scanned-summary"=>"42", "supp-data"=>"51"}
- {"month"=>"7", "scanned-page-browse"=>"33", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2007", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"93", "scanned-summary"=>"52", "supp-data"=>"44"}
- {"scanned-page-browse"=>"21", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"7", "pdf"=>"0", "year"=>"2007", "figure"=>"61", "scanned-summary"=>"33", "supp-data"=>"34"}
- {"month"=>"9", "scanned-page-browse"=>"16", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"1", "year"=>"2007", "pdf"=>"1", "unique-ip"=>"3", "figure"=>"49", "scanned-summary"=>"28", "supp-data"=>"25"}
- {"scanned-page-browse"=>"16", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"11", "pdf"=>"0", "year"=>"2007", "figure"=>"76", "scanned-summary"=>"48", "supp-data"=>"38"}
- {"month"=>"11", "scanned-page-browse"=>"21", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2007", "pdf"=>"1", "unique-ip"=>"3", "figure"=>"67", "scanned-summary"=>"40", "supp-data"=>"40"}
- {"scanned-page-browse"=>"22", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"2", "pdf"=>"0", "year"=>"2007", "figure"=>"68", "scanned-summary"=>"39", "supp-data"=>"36"}
- {"month"=>"1", "scanned-page-browse"=>"13", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"5", "figure"=>"47", "scanned-summary"=>"24", "supp-data"=>"32"}
- {"scanned-page-browse"=>"16", "month"=>"2", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"6", "pdf"=>"0", "year"=>"2008", "figure"=>"55", "scanned-summary"=>"31", "supp-data"=>"32"}
- {"month"=>"3", "scanned-page-browse"=>"18", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"58", "scanned-summary"=>"38", "supp-data"=>"35"}
- {"scanned-page-browse"=>"10", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"6", "pdf"=>"0", "year"=>"2008", "figure"=>"49", "scanned-summary"=>"32", "supp-data"=>"34"}
- {"month"=>"5", "scanned-page-browse"=>"17", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "year"=>"2008", "pdf"=>"0", "unique-ip"=>"4", "figure"=>"71", "scanned-summary"=>"49", "supp-data"=>"46"}
- {"scanned-page-browse"=>"8", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"5", "pdf"=>"1", "year"=>"2008", "figure"=>"39", "scanned-summary"=>"24", "supp-data"=>"23"}
- {"month"=>"7", "scanned-page-browse"=>"19", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2008", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"66", "scanned-summary"=>"39", "supp-data"=>"42"}
- {"scanned-page-browse"=>"29", "month"=>"8", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"3", "unique-ip"=>"6", "pdf"=>"1", "year"=>"2008", "figure"=>"79", "scanned-summary"=>"39", "supp-data"=>"39"}
- {"month"=>"9", "scanned-page-browse"=>"17", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"2", "year"=>"2008", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"50", "scanned-summary"=>"26", "supp-data"=>"28"}
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- {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"27", "year"=>"2008", "pdf"=>"19", "unique-ip"=>"26", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"25", "unique-ip"=>"26", "pdf"=>"18", "year"=>"2008", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"8", "full-text"=>"43", "year"=>"2009", "pdf"=>"20", "unique-ip"=>"48", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"47", "unique-ip"=>"43", "pdf"=>"20", "year"=>"2009", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"47", "year"=>"2009", "pdf"=>"17", "unique-ip"=>"46", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"57", "unique-ip"=>"56", "pdf"=>"29", "year"=>"2009", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"31", "year"=>"2009", "pdf"=>"16", "unique-ip"=>"36", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"41", "unique-ip"=>"40", "pdf"=>"20", "year"=>"2009", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"2"}
- {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"38", "year"=>"2009", "pdf"=>"26", "unique-ip"=>"29", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"24", "unique-ip"=>"25", "pdf"=>"11", "year"=>"2009", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"1"}
- {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"29", "year"=>"2009", "pdf"=>"15", "unique-ip"=>"30", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
- {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"10", "unique-ip"=>"11", "pdf"=>"13", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
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- {"unique-ip"=>"28", "full-text"=>"27", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
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Relative Metric
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