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{"title"=>"Disclosure of investigators' recruitment performance in multicenter clinical trials: A further step for research transparency", "type"=>"journal", "authors"=>[{"first_name"=>"Rafael", "last_name"=>"Dal-Ré", "scopus_author_id"=>"7006227304"}, {"first_name"=>"David", "last_name"=>"Moher", "scopus_author_id"=>"7005443800"}, {"first_name"=>"Christian", "last_name"=>"Gluud", "scopus_author_id"=>"7004884514"}, {"first_name"=>"Shaun", "last_name"=>"Treweek", "scopus_author_id"=>"6603838890"}, {"first_name"=>"Jacques", "last_name"=>"Demotes-Mainard", "scopus_author_id"=>"6701750825"}, {"first_name"=>"Xavier", "last_name"=>"Carné", "scopus_author_id"=>"7004232457"}], "year"=>2011, "source"=>"PLoS Medicine", "identifiers"=>{"scopus"=>"2-s2.0-84855174104", "pmid"=>"22215987", "sgr"=>"84855174104", "doi"=>"10.1371/journal.pmed.1001149", "isbn"=>"1549-1676 (Electronic)\r1549-1277 (Linking)", "issn"=>"15491277", "pui"=>"364014893"}, "id"=>"ca79eb78-a6d4-393a-ae02-f0b75479a124", "abstract"=>"Rafael Dal-Re and colleagues argue that the recruitment targets and performance of all site investigators in multi-centre clinical trials should be disclosed in trial registration sites before a trial starts, and when it ends.", "link"=>"http://www.mendeley.com/research/disclosure-investigators-recruitment-performance-multicenter-clinical-trials-further-step-research-t", "reader_count"=>32, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>2, "Student > Doctoral Student"=>4, "Researcher"=>10, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>1, "Other"=>2, "Student > Master"=>4, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>2, "Student > Doctoral Student"=>4, "Researcher"=>10, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>1, "Other"=>2, "Student > Master"=>4, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Biochemistry, Genetics and Molecular Biology"=>1, "Nursing and Health Professions"=>1, "Mathematics"=>1, "Medicine and Dentistry"=>14, "Philosophy"=>1, "Business, Management and Accounting"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>2, "Psychology"=>1, "Social Sciences"=>4, "Computer Science"=>1, "Immunology and Microbiology"=>1, "Engineering"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>14}, "Social Sciences"=>{"Social Sciences"=>4}, "Psychology"=>{"Psychology"=>1}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>2}, "Engineering"=>{"Engineering"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Philosophy"=>{"Philosophy"=>1}}, "reader_count_by_country"=>{"Finland"=>1, "United Kingdom"=>1, "France"=>2, "Indonesia"=>1}, "group_count"=>4}

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• http://doi.org/10.1186/s13063-015-0653-x
• http://doi.org/10.1038/nm0212-186a
• http://doi.org/10.1590/s0104-12902018180292
• http://doi.org/10.1038/nrclinonc.2012.33
• http://doi.org/10.1186/s40814-015-0009-z
• http://doi.org/10.1186/1745-6215-14-436
• http://doi.org/10.1186/s12998-019-0253-z
• http://doi.org/10.1371/journal.pone.0160464
• http://doi.org/10.1186/1471-2288-12-131
• http://doi.org/10.1371/journal.pone.0149416
• http://doi.org/10.1016/j.ejim.2016.06.026

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Figshare

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• {"files"=>["https://ndownloader.figshare.com/files/698074"], "description"=>"<p>If there is more than one principal investigator in a site all the information should be provided on all of them.</p>a<p>Multiple locations may be specified on ClinicalTrials.gov. Currently, when provided, the name (and contact details) of a contact person (not necessarily the site principal investigator) is usually given. On the other hand, there are examples in which contact details of all site principal investigators are provided: these are multicenter clinical trials sponsored by, for instance, nonprofit organizations (e.g., NCT01264445), governmental institutions (e.g., NCT01108614), research foundations (e.g., NCT00662220), industry (e.g., NCT00944905), universities (e.g., NCT00973154), collaborative groups (e.g., NCT00209209), or hospitals (e.g., NCT00756600) <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001149#pmed.1001149-National1\" target=\"_blank\">[6]</a>.</p>b<p>Due to early achievement of the number of (randomized) participants needed in the clinical trial.</p>c<p>When the trial is terminated, for whatever reason, before completing the expected recruitment. Currently ClinicalTrials.gov allows inclusion of information regarding suspended, terminated, or withdrawn studies providing “a brief explanation of why the study has been halted or terminated. If desired, use brief summary or detailed description to provide additional information. (Limit: 160 characters)” <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001149#pmed.1001149-National1\" target=\"_blank\">[6]</a>.</p>", "links"=>[], "tags"=>["elements", "investigators", "recruiting", "multicenter", "trials", "disclosed", "registry"], "article_id"=>368462, "categories"=>["Science Policy", "Biotechnology"], "users"=>["Rafael Dal-Ré", "David Moher", "Christian Gluud", "Shaun Treweek", "Jacques Demotes-Mainard", "Xavier Carné"], "doi"=>["https://dx.doi.org/10.1371/journal.pmed.1001149.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Key_elements_of_principal_investigators_at_each_recruiting_site_involved_in_multicenter_clinical_trials_to_be_disclosed_in_a_publicly_open_clinical_trial_registry_such_as_ClinicalTrials_gov_/368462", "title"=>"Key elements of principal investigators at each recruiting site involved in multicenter clinical trials to be disclosed in a publicly open clinical trial registry such as ClinicalTrials.gov.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-12-27 02:21:02"}

PMC Usage Stats | Further Information

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Relative Metric

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F1000Prime