Pregnancy Weight Gain and Childhood Body Weight: A Within-Family Comparison
- Publication Date
- October 01, 2013
- Journal
- PLOS Medicine
- Authors
- David S. Ludwig, Heather L. Rouse & Janet Currie
- Volume
- 10
- Issue
- 10
- Pages
- e1001521
- DOI
- https://dx.plos.org/10.1371/journal.pmed.1001521
- Publisher URL
- http://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1001521
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/24130460
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794857
- Europe PMC
- http://europepmc.org/abstract/MED/24130460
- Web of Science
- 000330370600001
- Scopus
- 84886627037
- Mendeley
- http://www.mendeley.com/research/pregnancy-weight-gain-childhood-body-weight-withinfamily-comparison
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Mendeley | Further Information
{"title"=>"Pregnancy Weight Gain and Childhood Body Weight: A Within-Family Comparison", "type"=>"journal", "authors"=>[{"first_name"=>"David S.", "last_name"=>"Ludwig", "scopus_author_id"=>"7102252503"}, {"first_name"=>"Heather L.", "last_name"=>"Rouse", "scopus_author_id"=>"12763443700"}, {"first_name"=>"Janet", "last_name"=>"Currie", "scopus_author_id"=>"7202634709"}], "year"=>2013, "source"=>"PLoS Medicine", "identifiers"=>{"sgr"=>"84886627037", "doi"=>"10.1371/journal.pmed.1001521", "isbn"=>"1549-1676 (Electronic)\\r1549-1277 (Linking)", "pmid"=>"24130460", "issn"=>"15491277", "scopus"=>"2-s2.0-84886627037", "pui"=>"370141399"}, "id"=>"2bc3a5b6-b88c-3e53-8bcf-4b739e15bd92", "abstract"=>"BACKGROUND: Excessive pregnancy weight gain is associated with obesity in the offspring, but this relationship may be confounded by genetic and other shared influences. We aimed to examine the association of pregnancy weight gain with body mass index (BMI) in the offspring, using a within-family design to minimize confounding.\\n\\nMETHODS AND FINDINGS: In this population-based cohort study, we matched records of all live births in Arkansas with state-mandated data on childhood BMI collected in public schools (from August 18, 2003 to June 2, 2011). The cohort included 42,133 women who had more than one singleton pregnancy and their 91,045 offspring. We examined how differences in weight gain that occurred during two or more pregnancies for each woman predicted her children's BMI and odds ratio (OR) of being overweight or obese (BMI≥85th percentile) at a mean age of 11.9 years, using a within-family design. For every additional kg of pregnancy weight gain, childhood BMI increased by 0.0220 (95% CI 0.0134-0.0306, p<0.0001) and the OR of overweight/obesity increased by 1.007 (CI 1.003-1.012, p = 0.0008). Variations in pregnancy weight gain accounted for a 0.43 kg/m(2) difference in childhood BMI. After adjustment for birth weight, the association of pregnancy weight gain with childhood BMI was attenuated but remained statistically significant (0.0143 kg/m(2) per kg of pregnancy weight gain, CI 0.0057-0.0229, p = 0.0007).\\n\\nCONCLUSIONS: High pregnancy weight gain is associated with increased body weight of the offspring in childhood, and this effect is only partially mediated through higher birth weight. Translation of these findings to public health obesity prevention requires additional study. Please see later in the article for the Editors' Summary.", "link"=>"http://www.mendeley.com/research/pregnancy-weight-gain-childhood-body-weight-withinfamily-comparison", "reader_count"=>55, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>8, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>5, "Student > Master"=>11, "Other"=>3, "Student > Bachelor"=>6, "Lecturer"=>3, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>8, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>5, "Student > Master"=>11, "Other"=>3, "Student > Bachelor"=>6, "Lecturer"=>3, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Agricultural and Biological Sciences"=>9, "Arts and Humanities"=>1, "Business, Management and Accounting"=>1, "Computer Science"=>1, "Economics, Econometrics and Finance"=>3, "Nursing and Health Professions"=>6, "Biochemistry, Genetics and Molecular Biology"=>1, "Materials Science"=>1, "Medicine and Dentistry"=>16, "Neuroscience"=>3, "Sports and Recreations"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Psychology"=>4, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>16}, "Social Sciences"=>{"Social Sciences"=>2}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Psychology"=>{"Psychology"=>4}, "Unspecified"=>{"Unspecified"=>5}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Neuroscience"=>{"Neuroscience"=>3}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>9}, "Computer Science"=>{"Computer Science"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>6}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}}, "reader_count_by_country"=>{"New Zealand"=>1, "Canada"=>2, "United States"=>2, "China"=>1, "Portugal"=>1}, "group_count"=>5}CrossRef
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Scopus | Further Information
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- {"id"=>"386247444591575040", "text"=>"Pregnancy weight gain and childhood obesity: http://t.co/L0rZFeJPsV", "created_at"=>"2013-10-04T21:52:21Z", "user"=>"JoaoBreda2", "user_name"=>"João Breda", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000422772115/db35d6e31d69c956b5d93a321847d754_normal.jpeg"}
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- {"id"=>"386299990470959104", "text"=>"> de peso en embarazo se asocia con obesidad infancia y no sólo x peso elevad en nacimiento! http://t.co/2B7w8a1U4z", "created_at"=>"2013-10-05T01:21:09Z", "user"=>"dracecicastillo", "user_name"=>"Cecilia Castillo L.", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000022168258/247c2f9cb3994e3d8eb393da2a5490b0_normal.jpeg"}
- {"id"=>"386300487189819393", "text"=>"RT @dracecicastillo: > de peso en embarazo se asocia con obesidad infancia y no sólo x peso elevad en nacimiento! http://t.co/2B7w8a1U4z", "created_at"=>"2013-10-05T01:23:07Z", "user"=>"leivarojas", "user_name"=>"Gonzalo Leiva Rojas", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000515243429/6401d19ef8f2c177d174a44b493d9559_normal.jpeg"}
- {"id"=>"386300574050029568", "text"=>"RT @dracecicastillo: > de peso en embarazo se asocia con obesidad infancia y no sólo x peso elevad en nacimiento! http://t.co/2B7w8a1U4z", "created_at"=>"2013-10-05T01:23:28Z", "user"=>"cecilitastar", "user_name"=>"cecilita", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000512985011/c080665c48b7397bfe83c406d7e68fc8_normal.jpeg"}
- {"id"=>"386604752479715328", "text"=>"RT @dracecicastillo: > de peso en embarazo se asocia con obesidad infancia y no sólo x peso elevad en nacimiento! http://t.co/2B7w8a1U4z", "created_at"=>"2013-10-05T21:32:10Z", "user"=>"Maite_inzunza", "user_name"=>"Mónica Rojas Inzunza", "user_profile_image"=>"http://a0.twimg.com/profile_images/3451393293/5bbbdbcd347b8d3fe821a0761c6f64fb_normal.jpeg"}
- {"id"=>"387089973952126976", "text"=>"Hoe dikker zwangere vrouw, hoe dikker kind. Niet alleen DNA en eten zijn oorzaak. Ook gewicht zwangerschap #dietist http://t.co/dIkuTmquvp", "created_at"=>"2013-10-07T05:40:16Z", "user"=>"basagricola", "user_name"=>"Bas Agricola", "user_profile_image"=>"http://a0.twimg.com/profile_images/2943819210/bacc49d48a35077e18bb469f44ec0de0_normal.jpeg"}
- {"id"=>"388227173754339328", "text"=>"PLOS Medicine: Pregnancy Weight Gain and Childhood Body Weight: A Within-Family Comparison http://t.co/EjXjA9ODCS", "created_at"=>"2013-10-10T08:59:05Z", "user"=>"armilegge", "user_name"=>"Armi Legge", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000142649571/8f1a9e5f6161e0921510d2edd580a371_normal.jpeg"}
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- {"id"=>"388795185926139904", "text"=>"Top story: PLOS Medicine: Pregnancy Weight Gain and Childhood Body Weight: A Wi… http://t.co/jZowM4AwJ4, see more http://t.co/V4GoKY97np", "created_at"=>"2013-10-11T22:36:10Z", "user"=>"ATP_CME", "user_name"=>"ATP EGYPT", "user_profile_image"=>"http://a0.twimg.com/profile_images/1337289872/DSCF1510_normal.JPG"}
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- {"id"=>"392032577336651777", "text"=>"PLOS Medicine: Pregnancy Weight Gain and Childhood Body Weight: A Within-Family Comparison http://t.co/k58to5wqDV", "created_at"=>"2013-10-20T21:00:24Z", "user"=>"impruvism", "user_name"=>"Armi Legge", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000138385632/f7132e7c996b0737688a87f629d55d22_normal.jpeg"}
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- {"id"=>"427982074470236160", "text"=>"http://t.co/Na1U8KtJbM \"regardless of your #genes, what you eat during those 40 weeks of pregnancy really does matter\"", "created_at"=>"2014-01-28T01:50:52Z", "user"=>"mobilewashunit", "user_name"=>"Andy Snyder", "user_profile_image"=>"http://pbs.twimg.com/profile_images/473389710/IMGA2510_normal.JPG"}
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PMC Usage Stats | Further Information
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