A Risk Prediction Model for the Assessment and Triage of Women with Hypertensive Disorders of Pregnancy in Low-Resourced Settings: The miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) Multi-country Prospective Cohort Study
- Publication Date
- January 21, 2014
- Journal
- PLOS Medicine
- Authors
- Beth A. Payne, Jennifer A. Hutcheon, J. Mark Ansermino, David R. Hall, et al
- Volume
- 11
- Issue
- 1
- Pages
- e1001589
- DOI
- https://dx.plos.org/10.1371/journal.pmed.1001589
- Publisher URL
- http://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1001589
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/24465185
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897359
- Europe PMC
- http://europepmc.org/abstract/MED/24465185
- Web of Science
- 000337975600008
- Scopus
- 84893745207
- Mendeley
- http://www.mendeley.com/research/risk-prediction-model-assessment-triage-women-hypertensive-disorders-pregnancy-lowresourced-settings
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Mendeley | Further Information
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S.", "last_name"=>"Joseph", "scopus_author_id"=>"25225855600"}, {"first_name"=>"Florence", "last_name"=>"Mirembe", "scopus_author_id"=>"6602331709"}, {"first_name"=>"Amanda", "last_name"=>"Noovao", "scopus_author_id"=>"56031600500"}, {"first_name"=>"Rahat", "last_name"=>"Qureshi", "scopus_author_id"=>"7006728965"}, {"first_name"=>"Tao", "last_name"=>"Duan", "scopus_author_id"=>"56919320500"}, {"first_name"=>"Erika", "last_name"=>"van Papendorp", "scopus_author_id"=>"56032457100"}, {"first_name"=>"Michael", "last_name"=>"Ssegirinya", "scopus_author_id"=>"56031987000"}, {"first_name"=>"Margaret", "last_name"=>"Sewagaba", "scopus_author_id"=>"56031472000"}, {"first_name"=>"Rose Mary", "last_name"=>"Byenkya", "scopus_author_id"=>"56031698300"}, {"first_name"=>"Betty", "last_name"=>"Namulema", "scopus_author_id"=>"6505671231"}, {"first_name"=>"Jane", "last_name"=>"Namiiro", "scopus_author_id"=>"56032025800"}, {"first_name"=>"Rose Mary", "last_name"=>"Nakayiza", "scopus_author_id"=>"56031547700"}, {"first_name"=>"Grace", "last_name"=>"Akao", "scopus_author_id"=>"56032135900"}, {"first_name"=>"Immaculate", "last_name"=>"Nankabirwa", "scopus_author_id"=>"56031147300"}, {"first_name"=>"Rehema", "last_name"=>"Nakazibwe", "scopus_author_id"=>"56031368500"}, {"first_name"=>"A.", "last_name"=>"Noorjahan", "scopus_author_id"=>"56031148800"}, {"first_name"=>"Farina", "last_name"=>"Azeem", "scopus_author_id"=>"56031747000"}, {"first_name"=>"Jennifer", "last_name"=>"Menzies", "scopus_author_id"=>"15731173800"}, {"first_name"=>"Fiona Broughton", "last_name"=>"Pipkin", "scopus_author_id"=>"55663840200"}, {"first_name"=>"A. M.", "last_name"=>"Côté", "scopus_author_id"=>"8598576700"}, {"first_name"=>"M. Joanne", "last_name"=>"Douglas", "scopus_author_id"=>"7202715872"}, {"first_name"=>"Andrée", "last_name"=>"Gruslin", "scopus_author_id"=>"6701429418"}, {"first_name"=>"Pippa", "last_name"=>"Kyle", "scopus_author_id"=>"23035202100"}, {"first_name"=>"Tang", "last_name"=>"Lee", "scopus_author_id"=>"55784403400"}, {"first_name"=>"Pam", "last_name"=>"Loughna", "scopus_author_id"=>"56031201300"}, {"first_name"=>"Swati", "last_name"=>"Mahajan", "scopus_author_id"=>"56032333900"}, {"first_name"=>"Alexi", "last_name"=>"Millman", "scopus_author_id"=>"56031604900"}, {"first_name"=>"M. Peter", "last_name"=>"Moore", "scopus_author_id"=>"23036239000"}, {"first_name"=>"Jean Marie", "last_name"=>"Moutquin", "scopus_author_id"=>"7006291666"}, {"first_name"=>"Annie", "last_name"=>"Ouellet", "scopus_author_id"=>"15751752600"}, {"first_name"=>"Graeme", "last_name"=>"Smith", "scopus_author_id"=>"7406736028"}, {"first_name"=>"Jimmy", "last_name"=>"Walker", "scopus_author_id"=>"7405589331"}, {"first_name"=>"Barry", "last_name"=>"Walters", "scopus_author_id"=>"7102217811"}, {"first_name"=>"Shoo", "last_name"=>"Lee", "scopus_author_id"=>"7601396360"}, {"first_name"=>"Jim", "last_name"=>"Russell", "scopus_author_id"=>"7404208893"}, {"first_name"=>"Mark", "last_name"=>"Brown", "scopus_author_id"=>"13310003600"}, {"first_name"=>"Greg", "last_name"=>"Davis", "scopus_author_id"=>"55454931000"}, {"first_name"=>"Steve", "last_name"=>"Robson", "scopus_author_id"=>"35300400200"}, {"first_name"=>"Michael", "last_name"=>"de Swiet", "scopus_author_id"=>"16210632800"}, {"first_name"=>"Marshall", "last_name"=>"Lindheimer", "scopus_author_id"=>"35327446400"}, {"first_name"=>"Jim", "last_name"=>"Roberts", "scopus_author_id"=>"35396054000"}, {"first_name"=>"Dorothy", "last_name"=>"Shaw", "scopus_author_id"=>"15077308400"}, {"first_name"=>"France", "last_name"=>"Donnay", "scopus_author_id"=>"6602250185"}], "year"=>2014, "source"=>"PLoS Medicine", "identifiers"=>{"issn"=>"15491277", "scopus"=>"2-s2.0-84893745207", "pui"=>"372349015", "doi"=>"10.1371/journal.pmed.1001589", "isbn"=>"1549-1277", "sgr"=>"84893745207", "pmid"=>"24465185"}, "id"=>"57a6ce97-c13e-3e9f-b33b-cafd0999fa84", "abstract"=>"BACKGROUND: Pre-eclampsia/eclampsia are leading causes of maternal mortality and morbidity, particularly in low- and middle- income countries (LMICs). We developed the miniPIERS risk prediction model to provide a simple, evidence-based tool to identify pregnant women in LMICs at increased risk of death or major hypertensive-related complications.\n\nMETHODS AND FINDINGS: From 1 July 2008 to 31 March 2012, in five LMICs, data were collected prospectively on 2,081 women with any hypertensive disorder of pregnancy admitted to a participating centre. Candidate predictors collected within 24 hours of admission were entered into a step-wise backward elimination logistic regression model to predict a composite adverse maternal outcome within 48 hours of admission. Model internal validation was accomplished by bootstrapping and external validation was completed using data from 1,300 women in the Pre-eclampsia Integrated Estimate of RiSk (fullPIERS) dataset. Predictive performance was assessed for calibration, discrimination, and stratification capacity. The final miniPIERS model included: parity (nulliparous versus multiparous); gestational age on admission; headache/visual disturbances; chest pain/dyspnoea; vaginal bleeding with abdominal pain; systolic blood pressure; and dipstick proteinuria. The miniPIERS model was well-calibrated and had an area under the receiver operating characteristic curve (AUC ROC) of 0.768 (95% CI 0.735-0.801) with an average optimism of 0.037. External validation AUC ROC was 0.713 (95% CI 0.658-0.768). A predicted probability ≥25% to define a positive test classified women with 85.5% accuracy. Limitations of this study include the composite outcome and the broad inclusion criteria of any hypertensive disorder of pregnancy. This broad approach was used to optimize model generalizability.\n\nCONCLUSIONS: The miniPIERS model shows reasonable ability to identify women at increased risk of adverse maternal outcomes associated with the hypertensive disorders of pregnancy. It could be used in LMICs to identify women who would benefit most from interventions such as magnesium sulphate, antihypertensives, or transportation to a higher level of care. Please see later in the article for the Editors' Summary.", "link"=>"http://www.mendeley.com/research/risk-prediction-model-assessment-triage-women-hypertensive-disorders-pregnancy-lowresourced-settings", "reader_count"=>116, "reader_count_by_academic_status"=>{"Unspecified"=>9, "Professor > Associate Professor"=>9, "Librarian"=>1, "Student > Doctoral Student"=>8, "Researcher"=>11, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>9, "Other"=>9, "Student > Master"=>24, "Student > Bachelor"=>8, "Lecturer"=>4, "Lecturer > Senior Lecturer"=>3, "Professor"=>11}, "reader_count_by_user_role"=>{"Unspecified"=>9, "Professor > Associate Professor"=>9, "Librarian"=>1, "Student > Doctoral Student"=>8, "Researcher"=>11, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>9, "Other"=>9, "Student > Master"=>24, "Student > Bachelor"=>8, "Lecturer"=>4, "Lecturer > Senior Lecturer"=>3, "Professor"=>11}, "reader_count_by_subject_area"=>{"Unspecified"=>11, "Agricultural and Biological Sciences"=>6, "Arts and Humanities"=>1, "Computer Science"=>4, "Engineering"=>3, "Environmental Science"=>1, "Nursing and Health Professions"=>10, "Medicine and Dentistry"=>68, "Neuroscience"=>2, "Design"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Psychology"=>1, "Social Sciences"=>6, "Immunology and Microbiology"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>68}, "Social Sciences"=>{"Social Sciences"=>6}, "Psychology"=>{"Psychology"=>1}, "Unspecified"=>{"Unspecified"=>11}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Design"=>{"Design"=>1}, "Engineering"=>{"Engineering"=>3}, "Neuroscience"=>{"Neuroscience"=>2}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>6}, "Computer Science"=>{"Computer Science"=>4}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>10}}, "reader_count_by_country"=>{"Canada"=>2, "United States"=>1, "Brazil"=>2, "Kazakhstan"=>1, "India"=>2}, "group_count"=>11}CrossRef
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Scopus | Further Information
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- {"id"=>"427870968699039744", "text"=>"#plos Accurately stratifying risk in women with #pregnancy #hypertension in resource-limited settings with miniPIERS http://t.co/4zSfLg5GKS", "created_at"=>"2014-01-27T18:29:23Z", "user"=>"pvondadelszen", "user_name"=>"Peter von Dadelszen", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3190642201/7d13dae5c9a5fc10923efebe2e09e743_normal.png"}
- {"id"=>"427872910670192640", "text"=>"RT @pvondadelszen: #plos Accurately stratifying risk in women with #pregnancy #hypertension in resource-limited settings with miniPIERS htt…", "created_at"=>"2014-01-27T18:37:06Z", "user"=>"UBCPreEMPT", "user_name"=>"UBC PRE_EMPT", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000729991735/a95b4025e0f1de114c6b97015fab1558_normal.png"}
- {"id"=>"427874424411279360", "text"=>"Our study to accurately risk stratify in women w/ #pregnancy #hypertension published in @PLOSMedicine :http://t.co/SXRvK304w2. #preeclampsia", "created_at"=>"2014-01-27T18:43:06Z", "user"=>"UBCPreEMPT", "user_name"=>"UBC PRE_EMPT", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000729991735/a95b4025e0f1de114c6b97015fab1558_normal.png"}
- {"id"=>"427888955804385280", "text"=>"RT @UBCPreEMPT: Our study to accurately risk stratify in women w/ #pregnancy #hypertension published in @PLOSMedicine :http://t.co/SXRvK304…", "created_at"=>"2014-01-27T19:40:51Z", "user"=>"CFRI", "user_name"=>"CFRI", "user_profile_image"=>"http://pbs.twimg.com/profile_images/89475858/CFRI_ClrNeg_normal.jpg"}
- {"id"=>"427946845139005440", "text"=>"RT @UBCPreEMPT: Our study to accurately risk stratify in women w/ #pregnancy #hypertension published in @PLOSMedicine :http://t.co/SXRvK304…", "created_at"=>"2014-01-27T23:30:53Z", "user"=>"cmqcc", "user_name"=>"CMQCC", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2188235656/CMQCC_square_normal.jpg"}
- {"id"=>"427955016054226945", "text"=>"RT @PLOSMedicine: Risk Prediction for Assessment & Triage of Women with Hypertensive Disorders of Pregnancy in Low-Resource Settings http:/…", "created_at"=>"2014-01-28T00:03:21Z", "user"=>"UBCPreEMPT", "user_name"=>"UBC PRE_EMPT", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000729991735/a95b4025e0f1de114c6b97015fab1558_normal.png"}
Counter
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- {"month"=>"3", "year"=>"2019", "pdf_views"=>"18", "xml_views"=>"2", "html_views"=>"51"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"46"}
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PMC Usage Stats | Further Information
- {"unique-ip"=>"12", "full-text"=>"8", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
- {"unique-ip"=>"105", "full-text"=>"118", "pdf"=>"54", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
- {"unique-ip"=>"77", "full-text"=>"88", "pdf"=>"44", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
- {"unique-ip"=>"55", "full-text"=>"64", "pdf"=>"36", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
- {"unique-ip"=>"55", "full-text"=>"63", "pdf"=>"46", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
- {"unique-ip"=>"52", "full-text"=>"58", "pdf"=>"24", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
- {"unique-ip"=>"34", "full-text"=>"48", "pdf"=>"27", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
- {"unique-ip"=>"30", "full-text"=>"27", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
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- {"unique-ip"=>"44", "full-text"=>"48", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
- {"unique-ip"=>"43", "full-text"=>"39", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
- {"unique-ip"=>"42", "full-text"=>"39", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
- {"unique-ip"=>"56", "full-text"=>"57", "pdf"=>"28", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
- {"unique-ip"=>"51", "full-text"=>"51", "pdf"=>"24", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
- {"unique-ip"=>"51", "full-text"=>"60", "pdf"=>"32", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
- {"unique-ip"=>"50", "full-text"=>"48", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
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- {"unique-ip"=>"43", "full-text"=>"45", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
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- {"unique-ip"=>"57", "full-text"=>"64", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"9"}
- {"unique-ip"=>"57", "full-text"=>"58", "pdf"=>"24", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
- {"unique-ip"=>"67", "full-text"=>"62", "pdf"=>"45", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
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- {"unique-ip"=>"25", "full-text"=>"27", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
- {"unique-ip"=>"29", "full-text"=>"25", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
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Relative Metric
{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Medicine and health sciences/Vascular medicine", "average_usage"=>[248]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[271]}]}Loading … 

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