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{"title"=>"A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders: Development and Outcomes of a Randomized Controlled Trial among Burmese Refugees in Thailand", "type"=>"journal", "authors"=>[{"first_name"=>"Paul", "last_name"=>"Bolton", "scopus_author_id"=>"7101689318"}, {"first_name"=>"Catherine", "last_name"=>"Lee", "scopus_author_id"=>"27171427700"}, {"first_name"=>"Emily E.", "last_name"=>"Haroz", "scopus_author_id"=>"55597705300"}, {"first_name"=>"Laura", "last_name"=>"Murray", "scopus_author_id"=>"12798633400"}, {"first_name"=>"Shannon", "last_name"=>"Dorsey", "scopus_author_id"=>"7003734061"}, {"first_name"=>"Courtland", "last_name"=>"Robinson", "scopus_author_id"=>"14054959000"}, {"first_name"=>"Ana M.", "last_name"=>"Ugueto", "scopus_author_id"=>"21735665600"}, {"first_name"=>"Judith", "last_name"=>"Bass", "scopus_author_id"=>"7202857775"}], "year"=>2014, "source"=>"PLoS Medicine", "identifiers"=>{"scopus"=>"2-s2.0-84920384691", "sgr"=>"84920384691", "issn"=>"15491676", "doi"=>"10.1371/journal.pmed.1001757", "pmid"=>"25386945", "isbn"=>"1549-1676 (Electronic)\\r1549-1277 (Linking)", "pui"=>"602078164"}, "id"=>"953f0c52-6757-3ff5-a32c-91eb6becda41", "abstract"=>"BACKGROUND Existing studies of mental health interventions in low-resource settings have employed highly structured interventions delivered by non-professionals that typically do not vary by client. Given high comorbidity among mental health problems and implementation challenges with scaling up multiple structured evidence-based treatments (EBTs), a transdiagnostic treatment could provide an additional option for approaching community-based treatment of mental health problems. Our objective was to test such an approach specifically designed for flexible treatments of varying and comorbid disorders among trauma survivors in a low-resource setting. . CONCLUSIONS CETA provided by lay counselors was highly effective across disorders among trauma survivors compared to WLCs. These results support the further development and testing of transdiagnostic approaches as possible treatment options alongside existing EBTs. TRIAL REGISTRATION ClinicalTrials.gov NCT01459068 Please see later in the article for the Editors' Summary.", "link"=>"http://www.mendeley.com/research/transdiagnostic-communitybased-mental-health-treatment-comorbid-disorders-development-outcomes-rando-3", "reader_count"=>120, "reader_count_by_academic_status"=>{"Unspecified"=>4, "Professor > Associate Professor"=>5, "Librarian"=>3, "Student > Doctoral Student"=>18, "Researcher"=>19, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>6, "Student > Master"=>22, "Other"=>8, "Student > Bachelor"=>13, "Lecturer"=>1, "Professor"=>5}, "reader_count_by_user_role"=>{"Unspecified"=>4, "Professor > Associate Professor"=>5, "Librarian"=>3, "Student > Doctoral Student"=>18, "Researcher"=>19, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>6, "Student > Master"=>22, "Other"=>8, "Student > Bachelor"=>13, "Lecturer"=>1, "Professor"=>5}, "reader_count_by_subject_area"=>{"Unspecified"=>7, "Nursing and Health Professions"=>4, "Medicine and Dentistry"=>32, "Agricultural and Biological Sciences"=>1, "Design"=>1, "Arts and Humanities"=>1, "Neuroscience"=>1, "Sports and Recreations"=>1, "Psychology"=>53, "Social Sciences"=>18, "Earth and Planetary Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Design"=>{"Design"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>32}, "Neuroscience"=>{"Neuroscience"=>1}, "Social Sciences"=>{"Social Sciences"=>18}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Psychology"=>{"Psychology"=>53}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>4}, "Unspecified"=>{"Unspecified"=>7}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"United States"=>1, "Brazil"=>1, "Italy"=>1, "United Kingdom"=>1, "Spain"=>1}, "group_count"=>22}

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• {"id"=>"532251388512706561", "text"=>"A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders http://t.co/dro6JRHFPp", "created_at"=>"2014-11-11T19:19:54Z", "user"=>"PLOSMedicine", "user_name"=>"PLOS Medicine", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2436335697/k93oob5au2gllc775hk5_normal.jpeg"}
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• {"id"=>"532274849323159552", "text"=>"#plos A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders: Development and Outcom.. http://t.co/zzqLdwGlP1", "created_at"=>"2014-11-11T20:53:07Z", "user"=>"bookapharmacist", "user_name"=>"Kazeem Olalekan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1859820850/3a_normal.png"}
• {"id"=>"532356957995147265", "text"=>"メンタルヘルス治療機関や医療者が少なくても、投獄や拷問等のトラウマ生存者の精神的健康を改善させたとの報告。A Transdiagnostic Community-Based Mental Health Treatment for … http://t.co/ONwi5CHncW", "created_at"=>"2014-11-12T02:19:24Z", "user"=>"uranus_2", "user_name"=>"マーキュリー２世", "user_profile_image"=>"http://pbs.twimg.com/profile_images/520761051646676992/x2e9wBQE_normal.png"}
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• {"id"=>"532564975085432832", "text"=>"RT @kkidia: strong evidence for #taskshifting with transdiagnostic approaches (CETA): http://t.co/xLsq1dwghy #globalmentalhealth @PLOSMedic…", "created_at"=>"2014-11-12T16:05:59Z", "user"=>"MHealthResearch", "user_name"=>"MentalHealthResearch", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1401471702/tower-rounded_normal.jpg"}
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• {"id"=>"532655247811158017", "text"=>"A transdiagnostic community-based #mentalhealth treatment for comorbid disorders\nhttp://t.co/kRJhSA4oH1 via @PLOSMedicine \n#mentalillness", "created_at"=>"2014-11-12T22:04:42Z", "user"=>"Tam_Roman", "user_name"=>"Tamara Anda Roman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/530146479797972992/mw1CA4pH_normal.jpeg"}
• {"id"=>"532671491788115968", "text"=>"#PLOSMedicine: A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders http://t.co/1QzrHUVN49", "created_at"=>"2014-11-12T23:09:14Z", "user"=>"deepalimpatel", "user_name"=>"deepali patel", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1504467523/twitter_normal.jpg"}
• {"id"=>"533398512507957249", "text"=>"A Controlled Trial of Community Mental Health Services for Comorbid Disorders among Burmese Refugees in Thailand http://t.co/bQ8i5DqAh8", "created_at"=>"2014-11-14T23:18:10Z", "user"=>"MScGlobMentHeal", "user_name"=>"GlobalMentalHealth", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1918089543/GMH_Picture_normal.png"}
• {"id"=>"534058070800740352", "text"=>"RT @debkaysen: evidence for #taskshifting for trauma w transdiagnostic approach http://t.co/Uj1dAWC4MO #globalmentalhealth @PLOSMedicine #I…", "created_at"=>"2014-11-16T18:59:01Z", "user"=>"MHealthResearch", "user_name"=>"MentalHealthResearch", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1401471702/tower-rounded_normal.jpg"}
• {"id"=>"534067786600157184", "text"=>"RT @debkaysen: evidence for #taskshifting for trauma w transdiagnostic approach http://t.co/Uj1dAWC4MO #globalmentalhealth @PLOSMedicine #I…", "created_at"=>"2014-11-16T19:37:37Z", "user"=>"SPSashidharan", "user_name"=>"S P Sashidharan", "user_profile_image"=>"http://pbs.twimg.com/profile_images/512926238394953728/kAqfYUP__normal.jpeg"}
• {"id"=>"622017023674056704", "text"=>"#acbswc Vikram Patel great transdiagnostic reults from CETA intervention (Bolton et al, PLoS One, 2015) http://t.co/TJ7WzsZZ7V", "created_at"=>"2015-07-17T12:16:29Z", "user"=>"RawsthorneMat", "user_name"=>"Mat Rawsthorne", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1876671139/Mat_for_work_normal.JPG"}

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/1787324"], "description"=>"<p>Modified scoring algorithms for HSCL and HTQ.</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235652, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.g001", "stats"=>{"downloads"=>3, "page_views"=>49, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Modified_scoring_algorithms_for_HSCL_and_HTQ_/1235652", "title"=>"Modified scoring algorithms for HSCL and HTQ.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787325"], "description"=>"<p>Flowchart of participants.</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235653, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.g002", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Flowchart_of_participants_/1235653", "title"=>"Flowchart of participants.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787327"], "description"=>"<p>Elements of CETA.</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235655, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t001", "stats"=>{"downloads"=>1, "page_views"=>20, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Elements_of_CETA_/1235655", "title"=>"Elements of CETA.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787328"], "description"=>"<p>Data are <i>n</i> (percent) unless otherwise indicated. Student's <i>t</i> tests and χ² tests found no significant differences between treatment and control groups (<i>p</i><0.05).</p>a<p>“Not married” category included <i>n</i> = 109 single, <i>n</i> = 24 widowed, and <i>n</i> = 38 divorced (in both treatment and control groups).</p>b<p>“Other” category includes <i>n</i> = 68 Karen, <i>n</i> = 2 Kayah, <i>n</i> = 2 Kachin, <i>n</i> = 16 Mon, <i>n</i> = 5 Chin, <i>n</i> = 4 Rakhine, and <i>n</i> = 4 Shan (in both treatment and control groups).</p>c<p>Current problems index included six items: food insecurity, negative workplace experiences, fear of police harassment, fear of detention, financial difficulties, and social relationship problems.</p><p>SD, standard deviation.</p><p>Baseline characteristics (<i>n</i> = 347).</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235656, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t002", "stats"=>{"downloads"=>0, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_characteristics_n_347_/1235656", "title"=>"Baseline characteristics (<i>n</i> = 347).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787329"], "description"=>"<p>“Pre-post change” is the change from pre-intervention to post-intervention.</p>a<p>Measured using Cohen's <i>d</i> statistic and pooled baseline variances.</p><p>**<i>p</i><0.001.</p><p>Average treatment effects (<i>n</i> = 347): unadjusted.</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235657, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t003", "stats"=>{"downloads"=>7, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Average_treatment_effects_n_347_unadjusted_/1235657", "title"=>"Average treatment effects (<i>n</i> = 347): unadjusted.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787330"], "description"=>"<p>Model-estimated differences after adjusting for baseline anxiety, age, sex, NGO affiliation, and education in all models and for covariates significantly associated with each specific outcome. All models include multiple imputation by chained equations for missing data and for missing outcomes due to loss to follow-up. Robust standard error estimators are used to account for clustering by counselor. “Pre-post change” is the change from pre-intervention to post-intervention.</p>a<p>Measured using Cohen's <i>d</i> statistic and pooled baseline variances.</p><p>**<i>p</i><0.001.</p><p>Average treatment effects (<i>n</i> = 347): adjusted for outcome specific covariates.</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235658, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t004", "stats"=>{"downloads"=>7, "page_views"=>19, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Average_treatment_effects_n_347_adjusted_for_outcome_specific_covariates_/1235658", "title"=>"Average treatment effects (<i>n</i> = 347): adjusted for outcome specific covariates.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787331"], "description"=>"<p>Reported baseline alcohol use score of eight or above on AUDIT; model weighted to account for loss to follow-up, and robust standard error estimators used to account for clustering by counselor. “Pre-post change” is the change from pre-intervention to post-intervention.</p><p>IQR, interquartile range.</p><p>Average treatment effects on alcohol use among alcohol users (<i>n</i> = 23).</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235659, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t005", "stats"=>{"downloads"=>1, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Average_treatment_effects_on_alcohol_use_among_alcohol_users_n_23_/1235659", "title"=>"Average treatment effects on alcohol use among alcohol users (<i>n</i> = 23).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787332"], "description"=>"<p>Model-estimated differences after adjusting for baseline anxiety, age, sex, NGO affiliation, and education in all models and for covariates significantly associated with each specific outcome. All models include multiple imputation by chained equations for missing data and for missing outcomes due to loss to follow-up. Robust standard error estimators are used to account for clustering by counselor.</p>a<p>Measured using Cohen's <i>d</i> statistic and pooled baseline variances.</p><p>*<i>p</i><0.05;</p><p>**<i>p</i><0.001.</p><p>Adjusted treatment effects stratified by affected sub-population (severe: <i>n</i> = 112; moderate: <i>n</i> = 235).</p>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235660, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1001757.t006", "stats"=>{"downloads"=>6, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Adjusted_treatment_effects_stratified_by_affected_sub_population_severe_n_112_moderate_n_235_/1235660", "title"=>"Adjusted treatment effects stratified by affected sub-population (severe: <i>n</i> = 112; moderate: <i>n</i> = 235).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-11-11 02:42:56"}
• {"files"=>["https://ndownloader.figshare.com/files/1787335", "https://ndownloader.figshare.com/files/1787336", "https://ndownloader.figshare.com/files/1787337", "https://ndownloader.figshare.com/files/1787338"], "description"=>"<div><p>Background</p><p>Existing studies of mental health interventions in low-resource settings have employed highly structured interventions delivered by non-professionals that typically do not vary by client. Given high comorbidity among mental health problems and implementation challenges with scaling up multiple structured evidence-based treatments (EBTs), a transdiagnostic treatment could provide an additional option for approaching community-based treatment of mental health problems. Our objective was to test such an approach specifically designed for flexible treatments of varying and comorbid disorders among trauma survivors in a low-resource setting.</p><p>Methods and Findings</p><p>We conducted a single-blinded, wait-list randomized controlled trial of a newly developed transdiagnostic psychotherapy, Common Elements Treatment Approach (CETA), for low-resource settings, compared with wait-list control (WLC). CETA was delivered by lay workers to Burmese survivors of imprisonment, torture, and related traumas, with flexibility based on client presentation. Eligible participants reported trauma exposure and met severity criteria for depression and/or posttraumatic stress (PTS). Participants were randomly assigned to CETA (<i>n</i> = 182) or WLC (<i>n</i> = 165). Outcomes were assessed by interviewers blinded to participant allocation using locally adapted standard measures of depression and PTS (primary outcomes) and functional impairment, anxiety symptoms, aggression, and alcohol use (secondary outcomes). Primary analysis was intent-to-treat (<i>n</i> = 347), including 73 participants lost to follow-up. CETA participants experienced significantly greater reductions of baseline symptoms across all outcomes with the exception of alcohol use (alcohol use analysis was confined to problem drinkers). The difference in mean change from pre-intervention to post-intervention between intervention and control groups was −0.49 (95% CI: −0.59, −0.40) for depression, −0.43 (95% CI: −0.51, −0.35) for PTS, −0.42 (95% CI: −0.58, −0.27) for functional impairment, −0.48 (95% CI: −0.61, −0.34) for anxiety, −0.24 (95% CI: −0.34, −0.15) for aggression, and −0.03 (95% CI: −0.44, 0.50) for alcohol use. This corresponds to a 77% reduction in mean baseline depression score among CETA participants compared to a 40% reduction among controls, with respective values for the other outcomes of 76% and 41% for anxiety, 75% and 37% for PTS, 67% and 22% for functional impairment, and 71% and 32% for aggression. Effect sizes (Cohen's <i>d</i>) were large for depression (<i>d</i> = 1.16) and PTS (<i>d</i> = 1.19); moderate for impaired function (<i>d</i> = 0.63), anxiety (<i>d</i> = 0.79), and aggression (<i>d</i> = 0.58); and none for alcohol use. There were no adverse events. Limitations of the study include the lack of long-term follow-up, non-blinding of service providers and participants, and no placebo or active comparison intervention.</p><p>Conclusions</p><p>CETA provided by lay counselors was highly effective across disorders among trauma survivors compared to WLCs. These results support the further development and testing of transdiagnostic approaches as possible treatment options alongside existing EBTs.</p><p>Trial registration</p><p><a href=\"http://clinicaltrials.gov/ct2/show/NCT01459068\" target=\"_blank\">ClinicalTrials.gov NCT01459068</a></p><p><i>Please see later in the article for the Editors' Summary</i></p></div>", "links"=>[], "tags"=>["EBTs.Trial registrationClinicalTrials.gov NCT 01459068Please", "wlc", "aggression", "randomized controlled trial", "pts", "health problems", "trauma survivors", "baseline depression score", "alcohol use analysis", "intervention", "ci", "anxiety", "alcohol use", "outcome", "transdiagnostic", "CETA participants", "Common Elements Treatment Approach", "Thailand BackgroundExisting studies", "impairment"], "article_id"=>1235663, "categories"=>["Uncategorised"], "users"=>["Paul Bolton", "Catherine Lee", "Emily E. Haroz", "Laura Murray", "Shannon Dorsey", "Courtland Robinson", "Ana M. Ugueto", "Judith Bass"], "doi"=>["https://dx.doi.org/10.1371/journal.pmed.1001757.s001", "https://dx.doi.org/10.1371/journal.pmed.1001757.s002", "https://dx.doi.org/10.1371/journal.pmed.1001757.s003", "https://dx.doi.org/10.1371/journal.pmed.1001757.s004"], "stats"=>{"downloads"=>14, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_Transdiagnostic_Community_Based_Mental_Health_Treatment_for_Comorbid_Disorders_Development_and_Outcomes_of_a_Randomized_Controlled_Trial_among_Burmese_Refugees_in_Thailand_/1235663", "title"=>"A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders: Development and Outcomes of a Randomized Controlled Trial among Burmese Refugees in Thailand", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2014-11-11 02:42:56"}

PMC Usage Stats | Further Information

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Relative Metric

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F1000Prime