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{"title"=>"Risks for central nervous system diseases among mobile phone subscribers: A Danish retrospective cohort study", "type"=>"journal", "authors"=>[{"first_name"=>"Joachim", "last_name"=>"Schüz", "scopus_author_id"=>"7003322462"}, {"first_name"=>"Gunhild", "last_name"=>"Waldemar", "scopus_author_id"=>"7006374342"}, {"first_name"=>"Jørgen H.", "last_name"=>"Olsen", "scopus_author_id"=>"7403259653"}, {"first_name"=>"Christoffer", "last_name"=>"Johansen", "scopus_author_id"=>"7101624018"}], "year"=>2009, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84887212448", "sgr"=>"84887212448", "pui"=>"354233125", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "pmid"=>"19194493", "doi"=>"10.1371/journal.pone.0004389"}, "id"=>"4e98b67b-08f4-3d3d-b49a-0bc1a8a421e5", "abstract"=>"The aim of this study was to investigate a possible link between cellular telephone use and risks for various diseases of the central nervous system (CNS). We conducted a large nationwide cohort study of 420 095 persons whose first cellular telephone subscription was between 1982 and 1995, who were followed through 2003 for hospital contacts for a diagnosis of a CNS disorder. Standardized hospitalization ratios (SHRs) were derived by dividing the number of hospital contacts in the cohort by the number expected in the Danish population. The SHRs were increased by 10-20% for migraine and vertigo. No associations were seen for amyotrophic lateral sclerosis, multiple sclerosis or epilepsy in women. SHRs decreased by 30-40% were observed for dementia (Alzheimer disease, vascular and other dementia), Parkinson disease and epilepsy among men. In analyses restricted to subscribers of 10 years or more, the SHRs remained similarly increased for migraine and vertigo and similarly decreased for Alzheimer disease and other dementia and epilepsy (in men); the other SHRs were close to unity. In conclusion, the excesses of migraine and vertigo observed in this first study on cellular telephones and CNS disease deserve further attention. An interplay of a healthy cohort effect and reversed causation bias due to prodromal symptoms impedes detection of a possible association with dementia and Parkinson disease. Identification of the factors that result in a healthy cohort might be of interest for elucidation of the etiology of these diseases.", "link"=>"http://www.mendeley.com/research/risks-central-nervous-system-diseases-among-mobile-phone-subscribers-danish-retrospective-cohort-stu", "reader_count"=>52, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>6, "Researcher"=>12, "Student > Doctoral Student"=>4, "Student > Ph. D. Student"=>3, "Student > Postgraduate"=>3, "Student > Master"=>9, "Other"=>3, "Student > Bachelor"=>6, "Lecturer"=>1, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>6, "Researcher"=>12, "Student > Doctoral Student"=>4, "Student > Ph. D. Student"=>3, "Student > Postgraduate"=>3, "Student > Master"=>9, "Other"=>3, "Student > Bachelor"=>6, "Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>6, "Agricultural and Biological Sciences"=>7, "Computer Science"=>2, "Decision Sciences"=>1, "Earth and Planetary Sciences"=>1, "Engineering"=>6, "Environmental Science"=>3, "Biochemistry, Genetics and Molecular Biology"=>1, "Medicine and Dentistry"=>17, "Neuroscience"=>2, "Physics and Astronomy"=>1, "Psychology"=>3, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>17}, "Social Sciences"=>{"Social Sciences"=>2}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>3}, "Unspecified"=>{"Unspecified"=>6}, "Environmental Science"=>{"Environmental Science"=>3}, "Engineering"=>{"Engineering"=>6}, "Neuroscience"=>{"Neuroscience"=>2}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>7}, "Computer Science"=>{"Computer Science"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}}, "reader_count_by_country"=>{"Canada"=>1, "Korea (South)"=>1, "United States"=>1, "Finland"=>1, "United Kingdom"=>1, "Spain"=>2}, "group_count"=>8}

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• http://doi.org/10.1016/j.neuroscience.2011.04.012
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• http://doi.org/10.3233/JAD-160165

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• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/5c62192b-3670-4cb7-ab3e-5bdaee00fc59", "title"=>"a tainted sample gives tainted results", "body"=>"There are some obvious errors in this study, which are the same erros I have commented upon in previous studies from the Danish Cancer society on mobile phone and power line radiation and cancer. etc.\nThe sample contains more that one kind of mobile telephony: in 1982 no GSM service was available in Denmark, so these older subjects had NMT handsets, which broadcast on a different frequencies...this sample was mixed with a newer sample, which includes GSM and GPRS handsets, but not 3G handsetw...therefore this sample is tainted...\n\nAs I have already pointed out for previous studies, this sample only SUBCRIBED to a mobile telephone service, no one actually know is all 420.000 people actually USED their phoes, how often, how close to the head, etc. so this is also a tainted sample!\n\nI will have a closer look at the statistics on this study, to see if the significance level is affected by the use of a large, inhoogeneous, and mutiply-tainted sample....", "isRemoved"=>false, "created"=>"2009-02-06T14:17:06Z", "lastModified"=>"2009-02-06T14:17:06Z", "creator"=>{"userId"=>"121493"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>false, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0004389", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2009-02-08T15:02:10Z", "replies"=>[{"type"=>"REPLY", "parentID"=>8465, "annotationUri"=>"info:doi/10.1371/reply/da92b6e1-7eea-4b87-b0d7-edcf8f2a8c09", "title"=>"RE: a tainted sample gives tainted results", "body"=>"Frontierscientist - you might want to read the paper before commenting on it.\n\nIf there were a problem, then the mixed telephony methods would lead to a mixture of different effect sizes, hence if only GSM (for example) was problematic, then effect would be stronger than the one estimated here.\n\nYour comment about use not being the same as subscription is correct, and is discussed in the paper. The conclusion, again, is that the effect would be underestimated.", "isRemoved"=>false, "created"=>"2009-02-08T15:02:10Z", "lastModified"=>"2009-02-08T15:02:10Z", "creator"=>{"userId"=>"8679"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>false, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0004389", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2009-02-08T15:02:10Z", "replies"=>[]}]}
• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/21034a82-2d15-449d-9ca2-6f16fcbfe94e", "title"=>"Migraineurs may preferentially have bought mobile phones early", "body"=>"It would be of interest to know whether the individuals who had reported to the hospitals with migraine had migraine before they bought their mobile phones.\r\n\r\nIt seems likely that people with bad migraines would have bought the phones early, as the mobile phones allow the migraineurs to contact their relatives or a taxi when an attack hits them away from public phones.\r\n\r\nAnne Bülow-Olsen\r\nChairman of the Danish Migraine Association", "isRemoved"=>false, "created"=>"2009-02-07T07:42:01Z", "lastModified"=>"2009-02-07T07:42:01Z", "creator"=>{"userId"=>"161063"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>false, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0004389", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2009-02-09T15:02:07Z", "replies"=>[{"type"=>"REPLY", "parentID"=>2831, "annotationUri"=>"info:doi/10.1371/reply/d3b0debf-1760-456f-8b3c-d77c23e97c1a", "title"=>"RE: Migraineurs may preferentially have bought mobile phones early", "body"=>"Reply from the authors: This is a very interesting suggestion and we agree this may indeed play a role in what we observed. We've already planned to address this issue, as in a further ongoing study of our group (Cosmos study, see www.cancer.dk/cosmos [in Danish]) we assess more detailed information on the course of exposure and disease as was available for the present register-linkage approach.", "isRemoved"=>false, "created"=>"2009-02-09T15:02:07Z", "lastModified"=>"2009-02-09T15:02:07Z", "creator"=>{"userId"=>"62109"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>false, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0004389", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2009-02-09T15:02:07Z", "replies"=>[]}]}

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Figshare

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PMC Usage Stats | Further Information

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Relative Metric

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F1000Prime