ALM

Is Antiretroviral Therapy Causing Long-Term Liver Damage? A Comparative Analysis of HIV-Mono-Infected and HIV/Hepatitis C Co-Infected Cohorts

Publication Date: February 18, 2009
Journal: PLOS ONE
Authors: Erica E. M. Moodie, Nitika Pant Pai & Marina B. Klein
Volume: 4
Issue: 2
Pages: e4517
DOI: https://dx.plos.org/10.1371/journal.pone.0004517
Publisher URL: http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0004517
PubMed: http://www.ncbi.nlm.nih.gov/pubmed/19223976
PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637977
Europe PMC: http://europepmc.org/abstract/MED/19223976
Web of Science: 000265485800017
Scopus: 84887212517
Mendeley: http://www.mendeley.com/research/antiretroviral-therapy-causing-longterm-liver-damage-comparative-analysis-hivmonoinfected-hivhepatit

Loading …

Events

Loading …

CiteULike02 May 10:13 UTC

CiteULike

Mendeley 2827 Apr 23:42 UTC

Mendeley | Further Information

{"title"=>"Is antiretroviral therapy causing long-term liver damage? A comparative analysis of HIV-mono-infected and HIV/hepatitis C co-infected cohorts", "type"=>"journal", "authors"=>[{"first_name"=>"Erica E M", "last_name"=>"Moodie", "scopus_author_id"=>"18434676900"}, {"first_name"=>"Nitika Pant", "last_name"=>"Pai", "scopus_author_id"=>"55576637900"}, {"first_name"=>"Marina B.", "last_name"=>"Klein", "scopus_author_id"=>"7404419562"}], "year"=>2009, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"354229994", "sgr"=>"84887212517", "pmid"=>"19223976", "scopus"=>"2-s2.0-84887212517", "isbn"=>"1932-6203", "doi"=>"10.1371/journal.pone.0004517", "issn"=>"19326203"}, "id"=>"82263e80-1452-3365-9b67-c2d864db559d", "abstract"=>"The effects of highly active antiretroviral therapy (HAART) on progression of hepatic fibrosis in HIV-hepatitis C virus (HCV) co-infection are not well understood. Deaths from liver diseases have risen in the post-HAART era, yet some cross-sectional studies have suggested that HAART use is associated with improved fibrosis rates. In a retrospective cohort of 533 HIV mono-infected and 127 HIV/HCV co-infected patients, followed between January 1991 and July 2005 at a university-based HIV clinic, we investigated the relationship between cumulative HAART exposure and hepatic fibrosis, as measured by the aspartate aminotransferase-to-platelet ratio index (APRI). We used a novel methodological approach to estimate the dose-response relationship of the effect of HAART exposure on APRI. HAART was associated with increasing APRI over time in HIV/HCV co-infected patients suggesting that they may be experiencing cumulative hepatotoxicity from antiretrovirals. The estimated median change (95% confidence interval) in APRI per one year of HAART intake was of -0.46% (-1.61% to 0.71%) in HIV mono-infected compared to 2.54% (-1.77% to 7.03%) in HIV/HCV co-infected patients. Similar results were found when the direct effect of HAART intake since the last visit was estimated on the change in APRI. HAART use associated is with increased APRI in patients with HIV/HCV co-infection. Therefore treatment for HCV infection may be required to slow the growing epidemic of end-stage liver disease in this population.", "link"=>"http://www.mendeley.com/research/antiretroviral-therapy-causing-longterm-liver-damage-comparative-analysis-hivmonoinfected-hivhepatit", "reader_count"=>26, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>1, "Librarian"=>1, "Researcher"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>2, "Other"=>2, "Student > Master"=>1, "Student > Bachelor"=>3, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>1, "Librarian"=>1, "Researcher"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>2, "Other"=>2, "Student > Master"=>1, "Student > Bachelor"=>3, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Nursing and Health Professions"=>2, "Agricultural and Biological Sciences"=>5, "Medicine and Dentistry"=>11, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Psychology"=>1, "Decision Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Psychology"=>{"Psychology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>5}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Unspecified"=>{"Unspecified"=>5}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"United States"=>1, "United Kingdom"=>1}, "group_count"=>2}

ORCID 129 Apr 06:45 UTC

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212517"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212517?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84887212517&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84887212517&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212517", "dc:identifier"=>"SCOPUS_ID:84887212517", "eid"=>"2-s2.0-84887212517", "dc:title"=>"Is antiretroviral therapy causing long-term liver damage? A comparative analysis of HIV-mono-infected and HIV/hepatitis C co-infected cohorts", "dc:creator"=>"Moodie E.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"4", "prism:issueIdentifier"=>"2", "prism:pageRange"=>nil, "prism:coverDate"=>"2009-02-18", "prism:coverDisplayDate"=>"18 February 2009", "prism:doi"=>"10.1371/journal.pone.0004517", "citedby-count"=>"45", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"McGill University", "affiliation-city"=>"Montreal", "affiliation-country"=>"Canada"}], "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e4517", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Web of Science®27 Nov 04:11 UTC

Web of Science® | Further Information

Article Coverage29 Apr 10:43 UTC

Article Coverage

Article Coverage Curated12 Dec 17:35 UTC

Article Coverage Curated

Facebook29 Jul 07:10 UTC

Facebook

{"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0004517", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments23 Oct 04:05 UTC

Journal Comments

Nature20 May 05:25 UTC

Nature

Reddit23 Apr 16:11 UTC

Research Blogging01 May 08:14 UTC

Research Blogging

ScienceSeeker19 Jul 17:07 UTC

ScienceSeeker | Further Information

Twitter09 Dec 10:39 UTC

Twitter

Wikipedia17 Mar 21:12 UTC

Wikipedia

Wordpress.com30 Aug 17:45 UTC

Wordpress.com | Further Information

Counter 415012 Dec 22:40 UTC

Counter

{"month"=>"2", "year"=>"2009", "pdf_views"=>"63", "xml_views"=>"0", "html_views"=>"208"}
{"month"=>"3", "year"=>"2009", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"59"}
{"month"=>"4", "year"=>"2009", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"32"}
{"month"=>"5", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"20"}
{"month"=>"6", "year"=>"2009", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"33"}
{"month"=>"7", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"27"}
{"month"=>"8", "year"=>"2009", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"22"}
{"month"=>"9", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"23"}
{"month"=>"10", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"23"}
{"month"=>"11", "year"=>"2009", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"19"}
{"month"=>"12", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"28"}
{"month"=>"1", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"25"}
{"month"=>"2", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"22"}
{"month"=>"3", "year"=>"2010", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"22"}
{"month"=>"4", "year"=>"2010", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"38"}
{"month"=>"5", "year"=>"2010", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"36"}
{"month"=>"6", "year"=>"2010", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"27"}
{"month"=>"7", "year"=>"2010", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"18"}
{"month"=>"8", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"23"}
{"month"=>"9", "year"=>"2010", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"31"}
{"month"=>"10", "year"=>"2010", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"20"}
{"month"=>"11", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"40"}
{"month"=>"12", "year"=>"2010", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"21"}
{"month"=>"1", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"18"}
{"month"=>"2", "year"=>"2011", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"29"}
{"month"=>"3", "year"=>"2011", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"42"}
{"month"=>"4", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"23"}
{"month"=>"5", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"17"}
{"month"=>"6", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"23"}
{"month"=>"7", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"17"}
{"month"=>"8", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"33"}
{"month"=>"9", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"31"}
{"month"=>"10", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"30"}
{"month"=>"11", "year"=>"2011", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"19"}
{"month"=>"12", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"31"}
{"month"=>"1", "year"=>"2012", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"34"}
{"month"=>"2", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"22"}
{"month"=>"3", "year"=>"2012", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"26"}
{"month"=>"4", "year"=>"2012", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"31"}
{"month"=>"5", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"24"}
{"month"=>"6", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
{"month"=>"7", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"20"}
{"month"=>"8", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"5", "html_views"=>"31"}
{"month"=>"9", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"31"}
{"month"=>"10", "year"=>"2012", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"37"}
{"month"=>"11", "year"=>"2012", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"24"}
{"month"=>"12", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"19"}
{"month"=>"1", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"36"}
{"month"=>"2", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"39"}
{"month"=>"3", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"31"}
{"month"=>"4", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"26"}
{"month"=>"5", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"52"}
{"month"=>"6", "year"=>"2013", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"50"}
{"month"=>"7", "year"=>"2013", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"51"}
{"month"=>"8", "year"=>"2013", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"41"}
{"month"=>"9", "year"=>"2013", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"37"}
{"month"=>"10", "year"=>"2013", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"21"}
{"month"=>"11", "year"=>"2013", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"47"}
{"month"=>"12", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"32"}
{"month"=>"1", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"11"}
{"month"=>"2", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"24"}
{"month"=>"3", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"40"}
{"month"=>"4", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"30"}
{"month"=>"5", "year"=>"2014", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"30"}
{"month"=>"6", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"21"}
{"month"=>"7", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"35"}
{"month"=>"8", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"24"}
{"month"=>"9", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"27"}
{"month"=>"10", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"19"}
{"month"=>"11", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"17"}
{"month"=>"12", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"12"}
{"month"=>"1", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"18"}
{"month"=>"2", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"2"}
{"month"=>"3", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"9"}
{"month"=>"4", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"2"}
{"month"=>"5", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"17"}
{"month"=>"6", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"10"}
{"month"=>"7", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"11"}
{"month"=>"8", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"11"}
{"month"=>"9", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"47"}
{"month"=>"10", "year"=>"2015", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"43"}
{"month"=>"11", "year"=>"2015", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"71"}
{"month"=>"12", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"56"}
{"month"=>"1", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"51"}
{"month"=>"2", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"14"}
{"month"=>"3", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"48"}
{"month"=>"4", "year"=>"2016", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"28"}
{"month"=>"5", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"22"}
{"month"=>"6", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
{"month"=>"7", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"12"}
{"month"=>"8", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"9"}
{"month"=>"9", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"21"}
{"month"=>"10", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"17"}
{"month"=>"11", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"26"}
{"month"=>"12", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"35"}
{"month"=>"1", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"21"}
{"month"=>"2", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"24"}
{"month"=>"3", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"37"}
{"month"=>"4", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"29"}
{"month"=>"5", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"31"}
{"month"=>"6", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"36"}
{"month"=>"7", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"15"}
{"month"=>"8", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"15"}
{"month"=>"9", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"23"}
{"month"=>"10", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"30"}
{"month"=>"11", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"30"}
{"month"=>"12", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"24"}
{"month"=>"1", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"11"}
{"month"=>"2", "year"=>"2018", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"10"}
{"month"=>"3", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"14"}
{"month"=>"4", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"8"}
{"month"=>"5", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"15"}
{"month"=>"6", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"18"}
{"month"=>"7", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"4", "html_views"=>"4"}
{"month"=>"8", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"10"}
{"month"=>"9", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"11"}
{"month"=>"10", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"11"}
{"month"=>"11", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"5"}
{"month"=>"12", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"7"}
{"month"=>"1", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"8"}
{"month"=>"2", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
{"month"=>"3", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"7"}
{"month"=>"4", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"9"}
{"month"=>"5", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"9"}
{"month"=>"6", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"8"}
{"month"=>"7", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"9"}
{"month"=>"8", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"12"}
{"month"=>"9", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"17"}
{"month"=>"10", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"6"}
{"month"=>"11", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"15"}
{"month"=>"12", "year"=>"2019", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"2"}

Figshare 2317 Apr 07:44 UTC

Figshare

{"files"=>["https://ndownloader.figshare.com/files/907652"], "description"=>"The plot includes point-wise 95% confidence bands for HIV mono-infected patients (solid line) and HIV/HCV co-infected patients (dashed line).", "links"=>[], "tags"=>["dose-response", "apri", "haart", "intake"], "article_id"=>578107, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.g003", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Estimated_dose_response_function_change_in_APRI_due_to_HAART_intake_between_clinical_visits_/578107", "title"=>"Estimated dose-response function: change in APRI due to HAART intake between clinical visits.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-18 02:15:07"}
{"files"=>["https://ndownloader.figshare.com/files/448987"], "description"=>"<div>The effects of highly active antiretroviral therapy (HAART) on progression of hepatic fibrosis in HIV-hepatitis C virus (HCV) co-infection are not well understood. Deaths from liver diseases have risen in the post-HAART era, yet some cross-sectional studies have suggested that HAART use is associated with improved fibrosis rates. In a retrospective cohort of 533 HIV mono-infected and 127 HIV/HCV co-infected patients, followed between January 1991 and July 2005 at a university-based HIV clinic, we investigated the relationship between cumulative HAART exposure and hepatic fibrosis, as measured by the aspartate aminotransferase-to-platelet ratio index (APRI). We used a novel methodological approach to estimate the dose-response relationship of the effect of HAART exposure on APRI. HAART was associated with increasing APRI over time in HIV/HCV co-infected patients suggesting that they may be experiencing cumulative hepatotoxicity from antiretrovirals. The estimated median change (95% confidence interval) in APRI per one year of HAART intake was of −0.46% (−1.61% to 0.71%) in HIV mono-infected compared to 2.54% (−1.77% to 7.03%) in HIV/HCV co-infected patients. Similar results were found when the direct effect of HAART intake since the last visit was estimated on the change in APRI. HAART use associated is with increased APRI in patients with HIV/HCV co-infection. Therefore treatment for HCV infection may be required to slow the growing epidemic of end-stage liver disease in this population.</div>", "links"=>[], "tags"=>["antiretroviral", "causing", "comparative", "hiv-mono-infected", "co-infected", "cohorts"], "article_id"=>148484, "categories"=>["Biological Sciences", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Is_Antiretroviral_Therapy_Causing_Long_Term_Liver_Damage_A_Comparative_Analysis_of_HIV_Mono_Infected_and_HIV_Hepatitis_C_Co_Infected_Cohorts/148484", "title"=>"Is Antiretroviral Therapy Causing Long-Term Liver Damage? A Comparative Analysis of HIV-Mono-Infected and HIV/Hepatitis C Co-Infected Cohorts", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-02-18 02:21:24"}
{"files"=>["https://ndownloader.figshare.com/files/907445"], "description"=>"A directed acyclic graph of the relationship between HAART exposure and APRI over time, where potentially confounding variables such as, for example, CD4+ T-cell counts, are represented by X. The Generalized Propensity Score permits unbiased estimation of the direct (or cross-sectional) effect, α, of most recent HAART intake on the response.", "links"=>[], "tags"=>["causal"], "article_id"=>577903, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.g001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Postulated_causal_diagram_/577903", "title"=>"Postulated causal diagram.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-18 02:11:43"}
{"files"=>["https://ndownloader.figshare.com/files/907904"], "description"=>"For continuous variables, statistics reported are median (range). For categorical variables statistics reported are count (%).Abbreviations: APRI, AST to platelet ratio index; HAART, highly active antiretroviral therapy; HCV, hepatitis C infection.", "links"=>[], "tags"=>["characteristics", "viral", "co-infection", "by-interval"], "article_id"=>578359, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.t002", "stats"=>{"downloads"=>5, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_characteristics_according_viral_co_infection_status_individuals_used_to_assess_the_by_interval_effects_/578359", "title"=>"Baseline characteristics according viral co-infection status (individuals used to assess the by-interval effects).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-02-18 02:19:19"}
{"files"=>["https://ndownloader.figshare.com/files/907930"], "description"=>"For continuous variables, statistics reported are median (range). For categorical variables statistics reported are count (%).Abbreviations: APRI, AST to platelet ratio index; HAART, highly active antiretroviral therapy; HCV, hepatitis C infection.", "links"=>[], "tags"=>["characteristics", "viral", "co-infection"], "article_id"=>578392, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.t001", "stats"=>{"downloads"=>3, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_characteristics_according_viral_co_infection_status_/578392", "title"=>"Baseline characteristics according viral co-infection status.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-02-18 02:19:52"}
{"files"=>["https://ndownloader.figshare.com/files/907754"], "description"=>"The plot includes point-wise 95% confidence bands for HIV mono-infected patients (solid line) and HIV/HCV co-infected patients (dashed line).", "links"=>[], "tags"=>["dose-response", "apri", "cumulative", "haart"], "article_id"=>578212, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.g004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Estimated_dose_response_function_APRI_due_to_cumulative_HAART_intake_/578212", "title"=>"Estimated dose-response function: APRI due to cumulative HAART intake.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-18 02:16:52"}
{"files"=>["https://ndownloader.figshare.com/files/907525"], "description"=>"The figure on the left is HIV-infected and on the right is the HIV/HCV co-infected patients; 15 data points in mono-infected persons and 39 points in co-infected persons have APRI scores above 4.0.", "links"=>[], "tags"=>["cumulative", "haart", "years"], "article_id"=>577983, "categories"=>["Computational Biology", "Medicine", "Neuroscience"], "users"=>["Erica E. M. Moodie", "Nitika Pant Pai", "Marina B. Klein"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004517.g002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_APRI_by_cumulative_HAART_exposure_in_years_over_the_course_of_the_study_/577983", "title"=>"APRI by cumulative HAART exposure in years over the course of the study.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-18 02:13:03"}

PMC Usage Stats 170517 Nov 14:34 UTC

PMC Usage Stats | Further Information

{"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "year"=>"2010", "pdf"=>"11", "unique-ip"=>"16", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"10", "unique-ip"=>"11", "pdf"=>"8", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "year"=>"2010", "pdf"=>"10", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"16", "unique-ip"=>"16", "pdf"=>"11", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"11", "year"=>"2010", "pdf"=>"11", "unique-ip"=>"13", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"15", "unique-ip"=>"16", "pdf"=>"17", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"13", "year"=>"2010", "pdf"=>"13", "unique-ip"=>"15", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"15", "unique-ip"=>"15", "pdf"=>"13", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"17", "year"=>"2010", "pdf"=>"14", "unique-ip"=>"21", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"8", "unique-ip"=>"12", "pdf"=>"11", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "year"=>"2010", "pdf"=>"9", "unique-ip"=>"12", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
{"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "unique-ip"=>"8", "pdf"=>"8", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"16", "year"=>"2011", "pdf"=>"10", "unique-ip"=>"17", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"15", "unique-ip"=>"16", "pdf"=>"11", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"8", "year"=>"2011", "pdf"=>"6", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"11", "unique-ip"=>"10", "pdf"=>"5", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"3", "year"=>"2011", "pdf"=>"2", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"10", "unique-ip"=>"12", "pdf"=>"6", "year"=>"2011", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "year"=>"2011", "pdf"=>"2", "unique-ip"=>"7", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "unique-ip"=>"8", "pdf"=>"3", "year"=>"2011", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"7", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "unique-ip"=>"15", "pdf"=>"9", "year"=>"2011", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"1"}
{"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"6", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"5", "pdf"=>"5", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"13", "year"=>"2012", "pdf"=>"5", "unique-ip"=>"11", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"6", "pdf"=>"2", "year"=>"2012", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"16", "year"=>"2012", "pdf"=>"9", "unique-ip"=>"16", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "unique-ip"=>"8", "pdf"=>"6", "year"=>"2012", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2012", "pdf"=>"3", "unique-ip"=>"8", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"36", "unique-ip"=>"32", "pdf"=>"33", "year"=>"2009", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"1"}
{"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"67", "year"=>"2009", "pdf"=>"54", "unique-ip"=>"67", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
{"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"83", "unique-ip"=>"74", "pdf"=>"60", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"4"}
{"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"39", "year"=>"2009", "pdf"=>"33", "unique-ip"=>"41", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"26", "unique-ip"=>"23", "pdf"=>"10", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"28", "year"=>"2009", "pdf"=>"26", "unique-ip"=>"30", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"16", "unique-ip"=>"18", "pdf"=>"19", "year"=>"2009", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"24", "year"=>"2009", "pdf"=>"22", "unique-ip"=>"25", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"11", "unique-ip"=>"10", "pdf"=>"8", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"22", "year"=>"2009", "pdf"=>"14", "unique-ip"=>"21", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"16", "unique-ip"=>"15", "pdf"=>"8", "year"=>"2009", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
{"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"3", "year"=>"2012", "pdf"=>"2", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
{"unique-ip"=>"12", "full-text"=>"9", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
{"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2012", "month"=>"9"}
{"unique-ip"=>"10", "full-text"=>"16", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
{"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
{"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
{"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
{"unique-ip"=>"2", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
{"unique-ip"=>"8", "full-text"=>"4", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
{"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
{"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
{"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
{"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
{"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
{"unique-ip"=>"8", "full-text"=>"5", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
{"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
{"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
{"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
{"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
{"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
{"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
{"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
{"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
{"unique-ip"=>"9", "full-text"=>"4", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
{"unique-ip"=>"15", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
{"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
{"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
{"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
{"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
{"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
{"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
{"unique-ip"=>"5", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
{"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
{"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
{"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"10"}
{"unique-ip"=>"11", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"11"}
{"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
{"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
{"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
{"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
{"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
{"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
{"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
{"unique-ip"=>"1", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
{"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
{"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
{"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
{"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
{"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
{"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
{"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
{"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
{"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
{"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
{"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
{"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
{"unique-ip"=>"3", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
{"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}

Relative Metric 132321710 May 16:16 UTC

Relative Metric

{"start_date"=>"2009-01-01T00:00:00Z", "end_date"=>"2009-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[349, 614, 744, 851, 955, 1059, 1167, 1262, 1352, 1431, 1516, 1593, 1668, 1746, 1817, 1883, 1950, 2017, 2075, 2141, 2198, 2254, 2313, 2368, 2424, 2474, 2534, 2591, 2651, 2710, 2776, 2837, 2892, 2953, 3014, 3072, 3130, 3186, 3251, 3307, 3366, 3427, 3500, 3561, 3627, 3688, 3759, 3821, 3888, 3950, 4010, 4070, 4131, 4189, 4242, 4307, 4370, 4431, 4491, 4549, 4608]}, {"subject_area"=>"/Biology and life sciences/Developmental biology", "average_usage"=>[315, 570, 717, 826, 931, 1027, 1137, 1224, 1308, 1379, 1458, 1542, 1613, 1694, 1768, 1841, 1909, 1957, 2019, 2082, 2127, 2182, 2232, 2290, 2352, 2419, 2476, 2525, 2572, 2627, 2670, 2722, 2800, 2846, 2901, 2963, 3017, 3078, 3136, 3210, 3253, 3303, 3366, 3431, 3486, 3538, 3600, 3663, 3723, 3776, 3815, 3880, 3966, 4036, 4103, 4145, 4193, 4232, 4304, 4369, 4426]}, {"subject_area"=>"/Biology and life sciences/Microbiology", "average_usage"=>[335, 610, 750, 871, 981, 1081, 1172, 1282, 1369, 1458, 1543, 1620, 1705, 1788, 1862, 1932, 2007, 2050, 2115, 2179, 2237, 2292, 2361, 2412, 2462, 2524, 2583, 2645, 2709, 2773, 2835, 2892, 2955, 3012, 3069, 3129, 3199, 3256, 3316, 3382, 3447, 3501, 3560, 3624, 3697, 3774, 3846, 3906, 3979, 4035, 4080, 4133, 4201, 4264, 4300, 4371, 4431, 4489, 4553, 4620, 4681]}, {"subject_area"=>"/Biology and life sciences/Organisms", "average_usage"=>[337, 605, 735, 844, 939, 1037, 1139, 1214, 1300, 1375, 1461, 1543, 1619, 1693, 1768, 1827, 1881, 1948, 2013, 2066, 2118, 2172, 2227, 2270, 2325, 2386, 2443, 2504, 2565, 2609, 2659, 2731, 2792, 2857, 2920, 2984, 3051, 3101, 3165, 3213, 3276, 3344, 3397, 3462, 3512, 3561, 3629, 3710, 3779, 3847, 3897, 3949, 4013, 4086, 4140, 4180, 4239, 4288, 4344, 4409, 4470]}, {"subject_area"=>"/Medicine and health sciences/Gastroenterology and hepatology", "average_usage"=>[242, 559, 687, 792, 882, 986, 1060, 1147, 1217, 1273, 1341, 1431, 1497, 1555, 1613, 1689, 1745, 1804, 1865, 1925, 1987, 2020, 2050, 2087, 2139, 2188, 2258, 2299, 2351, 2412, 2477, 2538, 2584, 2633, 2691, 2726, 2770, 2816, 2892, 2935, 3016, 3136, 3253, 3314, 3468, 3523, 3575, 3634, 3687, 3716, 3749, 3781, 3810, 3835, 3877, 3900, 3924, 3983, 4018, 4052, 4081, 4113]}, {"subject_area"=>"/Medicine and health sciences/Immunology", "average_usage"=>[306, 552, 683, 801, 902, 1004, 1103, 1192, 1279, 1350, 1434, 1503, 1564, 1641, 1705, 1779, 1833, 1887, 1946, 2001, 2054, 2105, 2167, 2218, 2270, 2307, 2358, 2410, 2454, 2504, 2560, 2608, 2656, 2713, 2757, 2807, 2856, 2912, 2959, 3010, 3059, 3111, 3162, 3216, 3282, 3336, 3393, 3453, 3512, 3569, 3623, 3687, 3746, 3792, 3838, 3888, 3938, 3997, 4059, 4114, 4152]}, {"subject_area"=>"/Medicine and health sciences/Pathology and laboratory medicine", "average_usage"=>[302, 565, 710, 814, 921, 1026, 1126, 1222, 1311, 1409, 1491, 1580, 1659, 1736, 1809, 1874, 1947, 2004, 2061, 2133, 2186, 2236, 2302, 2362, 2441, 2494, 2550, 2603, 2651, 2711, 2785, 2840, 2904, 2962, 3018, 3066, 3133, 3181, 3253, 3300, 3357, 3409, 3459, 3556, 3621, 3657, 3709, 3784, 3856, 3886, 3958, 4027, 4081, 4124, 4183, 4241, 4297, 4338, 4391, 4437, 4488]}, {"subject_area"=>"/Medicine and health sciences/Public and occupational health", "average_usage"=>[304, 638, 786, 902, 1029, 1134, 1234, 1324, 1435, 1536, 1617, 1727, 1849, 1939, 2053, 2141, 2211, 2275, 2362, 2414, 2482, 2575, 2623, 2683, 2734, 2809, 2861, 2894, 2936, 2993, 3056, 3107, 3158, 3220, 3266, 3327, 3405, 3463, 3556, 3600, 3761, 3810, 3875, 3918, 3998, 4050, 4114, 4153, 4238, 4308, 4368, 4436, 4506, 4565, 4645, 4707, 4765, 4820, 4875, 4948, 5008, 5076]}]}

F1000Prime11 Dec 11:40 UTC

F1000Prime

Loading …

There are currently no alerts

Mendeley | Further Information

ORCID | Further Information

Europe PMC Citations | Further Information

PubMed Central | Further Information

Scopus | Further Information

Web of Science® | Further Information

ScienceSeeker | Further Information

Wordpress.com | Further Information

PMC Usage Stats | Further Information