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{"title"=>"What is new for an old molecule? systematic review and recommendations on the use of resveratrol", "type"=>"generic", "authors"=>[{"first_name"=>"Ole", "last_name"=>"Vang", "scopus_author_id"=>"56055987000"}, {"first_name"=>"Nihal", "last_name"=>"Ahmad", "scopus_author_id"=>"7202343847"}, {"first_name"=>"Clifton A.", "last_name"=>"Baile", "scopus_author_id"=>"35309412900"}, {"first_name"=>"Joseph A.", "last_name"=>"Baur", "scopus_author_id"=>"14038740300"}, {"first_name"=>"Karen", "last_name"=>"Brown", "scopus_author_id"=>"7404382777"}, {"first_name"=>"Anna", "last_name"=>"Csiszar", "scopus_author_id"=>"6603855913"}, {"first_name"=>"Dipak K.", "last_name"=>"Das", "scopus_author_id"=>"7402353061"}, {"first_name"=>"Dominique", "last_name"=>"Delmas", "scopus_author_id"=>"6603955122"}, {"first_name"=>"Carmem", "last_name"=>"Gottfried", "scopus_author_id"=>"6701465385"}, {"first_name"=>"Hung Yun", "last_name"=>"Lin", "scopus_author_id"=>"26643131700"}, {"first_name"=>"Qing Yong", "last_name"=>"Ma", "scopus_author_id"=>"8561795900"}, {"first_name"=>"Partha", "last_name"=>"Mukhopadhyay", "scopus_author_id"=>"14825346100"}, {"first_name"=>"Namasivayam", "last_name"=>"Nalini", "scopus_author_id"=>"7004312975"}, {"first_name"=>"John M.", "last_name"=>"Pezzuto", "scopus_author_id"=>"35392643400"}, {"first_name"=>"Tristan", "last_name"=>"Richard", "scopus_author_id"=>"7007044714"}, {"first_name"=>"Yogeshwer", "last_name"=>"Shukla", "scopus_author_id"=>"7005216145"}, {"first_name"=>"Young Joon", "last_name"=>"Surh", "scopus_author_id"=>"7006078097"}, {"first_name"=>"Thomas", "last_name"=>"Szekeres", "scopus_author_id"=>"7004356027"}, {"first_name"=>"Tomasz", "last_name"=>"Szkudelski", "scopus_author_id"=>"6701674299"}, {"first_name"=>"Thomas", "last_name"=>"Walle", "scopus_author_id"=>"7005995905"}, {"first_name"=>"Joseph M.", "last_name"=>"Wu", "scopus_author_id"=>"7409255188"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-79959261445", "sgr"=>"79959261445", "issn"=>"19326203", "doi"=>"10.1371/journal.pone.0019881", "pmid"=>"21698226", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)", "pui"=>"361966415"}, "id"=>"b920f11d-f4c2-3845-8478-ed717297ee2c", "abstract"=>"<sec> <title>Background</title> <p>Resveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid recommendations concerning the human intake of resveratrol based on available published scientific data are necessary. Such recommendations were formulated after the Resveratrol 2010 conference, held in September 2010 in Helsingør, Denmark.</p> </sec> <sec> <title>Methodology</title> <p>Literature search in databases as PubMed and ISI Web of Science in combination with manual search was used to answer the following five questions: ¹Can resveratrol be recommended in the prevention or treatment of human diseases?; ²Are there observed “side effects” caused by the intake of resveratrol in humans?; ³What is the relevant dose of resveratrol?; ⁴What valid data are available regarding an effect in various species of experimental animals?; ⁵Which relevant (overall) mechanisms of action of resveratrol have been documented?</p> </sec> <sec> <title>Conclusions/Significance</title> <p>The overall conclusion is that the published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources. On the other hand, animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials. Finally, we suggest directions for future research in resveratrol regarding its mechanism of action and its safety and toxicology in human subjects.</p> </sec>", "link"=>"http://www.mendeley.com/research/new-old-molecule-systematic-review-recommendations-resveratrol-2", "reader_count"=>197, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>12, "Researcher"=>29, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>10, "Student > Master"=>38, "Other"=>12, "Student > Bachelor"=>32, "Lecturer > Senior Lecturer"=>1, "Professor"=>8}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>12, "Researcher"=>29, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>10, "Student > Master"=>38, "Other"=>12, "Student > Bachelor"=>32, "Lecturer > Senior Lecturer"=>1, "Professor"=>8}, "reader_count_by_subject_area"=>{"Unspecified"=>10, "Agricultural and Biological Sciences"=>75, "Philosophy"=>1, "Business, Management and Accounting"=>1, "Chemical Engineering"=>2, "Chemistry"=>14, "Engineering"=>3, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>17, "Nursing and Health Professions"=>3, "Medicine and Dentistry"=>51, "Neuroscience"=>9, "Sports and Recreations"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>5, "Physics and Astronomy"=>1, "Psychology"=>1, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>51}, "Social Sciences"=>{"Social Sciences"=>2}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>1}, "Unspecified"=>{"Unspecified"=>10}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>5}, "Chemical Engineering"=>{"Chemical Engineering"=>2}, "Engineering"=>{"Engineering"=>3}, "Chemistry"=>{"Chemistry"=>14}, "Neuroscience"=>{"Neuroscience"=>9}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>75}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>17}, "Philosophy"=>{"Philosophy"=>1}}, "reader_count_by_country"=>{"Lebanon"=>1, "Canada"=>1, "Netherlands"=>2, "Czech Republic"=>1, "United States"=>5, "Japan"=>1, "Brazil"=>3, "Italy"=>3, "United Kingdom"=>1, "Malaysia"=>1, "India"=>2}, "group_count"=>6}

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Article Coverage

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• {"referral"=>"http://www.ettoday.net/news/20140310/332487.htm", "language"=>"", "title"=>"紅酒及葡萄籽的白藜蘆醇（resveratrol）有沒有效？ | ETtoday名家新聞 | ETtoday 新聞雲", "type"=>"Blog", "publication"=>"ETtoday 新聞雲", "published_on"=>"", "link_state"=>""}

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• {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0019881", "share_count"=>1, "like_count"=>1, "comment_count"=>0, "click_count"=>0, "total_count"=>2}

Journal Comments | Further Information

• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/9d5daa8c-726d-4693-85ac-63f8679efea8", "title"=>"The use of data from Dr. Dipak Das’s research group at Cardiovascular Research Center, University of Connecticut School of Medicine, recently suspected to be responsible for research misconduct", "body"=>"'''Background:''' The formulation of recommendations of the use of resveratrol in the present paper, includes several papers from Dr. Dipak Das’ research group at Cardiovascular Research Center, University of Connecticut School of Medicine who have recently been suspected to be responsible for several examples of research misconduct.\nBased on the uncertainties that have been raised by this case, some have in public raised the question whether the basis for the present recommendations released in 2011 is beginning to waver. This commentary is only discussing the impact of the case on the recommendations.\nTwo articles in the reference list herein is pointed out by the reviewing board of the University of Connecticut having examples of data fabrication (Special Review Board Report Investigation of Allegation of Research Misconduct Office of Research Integrity Case #DIO 3995): ^^1)^^ Dudley, J., Das, S., Mukherjee, S., Das, D.K. (2009) Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose,''Journal of Nutritional Biochemistry''. 20(6) pp. 443-452 (Figure 4, Figures 5 and 7) – reference 86; ^^2)^^ Das, S., Tosaki, A., Bagchi, D., Maulik, N., Das, D.K. (2006) Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen - activated protein kinase/mitogen - and stress - activated protein kinase 1/cAMP response element - binding protein signalling, ''Journal of Pharmacology and Experimental Therapeutics'', 317 (3), pp. 980-988 (Figure 9) – reference 87 .\nThe data of these two articles are used in the following sentence: ''“Resveratrol prevented the effects of ischemia at doses of 10 mg/kg, whereas higher doses were found to depress cardiac function and increase myocardial infarct size [86,87].”'' This statement is mainly based on data of figure 2 of reference 86 and figure 3 of reference 87. These two figures do not contain western blot data or corresponding types of data. \n'''Conclusion:''' The identified irregularities by the evaluation board of University of Connecticut School of Medicine, in the two papers from Dr. Das’ research group do not have any impact on the conclusions formulated herein. Only in case that the two papers are being retracted from ''Journal of Nutritional Biochemistry'' and ''Journal of Pharmacology and Experimental Therapeutics'', respectively, the statement given above have to be nullified.\nThe preventive effect of resveratrol on myocardial infarction is shown in various animal models and shown in a row of different laboratories and not only by the research group of Dr. Das or in the two papers under investigation here. Further, other cardio-protective effects of resveratrol have been observed, which includes reduction of atherosclerosis and hypertension. These additional data may be found in the present PLoS One paper as well. \nRecently, January 2012, Magyar et al. showed that resveratrol (10 mg/day) improved several of the biomarkers related to reduced coronary artery disease in a 3 month clinical study.\n \nOle Vang, Associate professor, Roskilde University, Denmark\n", "isRemoved"=>false, "created"=>"2012-01-19T12:42:34Z", "lastModified"=>"2012-01-19T12:42:34Z", "creator"=>{"userId"=>"149415"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"Author of the paper"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0019881", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2012-01-19T12:42:34Z", "replies"=>[]}

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• {"id"=>"371711959957123072", "text"=>"@COPDdoc @BootsSkincare Evidence for use of resveratrol as oral supplement is not flattering http://t.co/kQxzHa1CGt", "created_at"=>"2013-08-25T19:13:31Z", "user"=>"pash22", "user_name"=>"Ash Paul", "user_profile_image"=>"http://a0.twimg.com/profile_images/3295856896/66ab958422d28c521d0143bddbb90233_normal.jpeg"}
• {"id"=>"377843030725652481", "text"=>"\"Evidence does not justify recommendation of resveratrol for humans,beyond what can be obtained from dietary sources\" http://t.co/3sYcKwJytE", "created_at"=>"2013-09-11T17:16:13Z", "user"=>"IvorGoodbody", "user_name"=>"Ivor Goodbody", "user_profile_image"=>"http://a0.twimg.com/profile_images/1762170479/IvorG_PictoPaint_normal.jpg"}
• {"id"=>"409422600763228160", "text"=>"#Resveratrol evidence review: no proof of human benefits but promising anti-#cancer/#HeartDisease results in animals http://t.co/3sYcKwJytE", "created_at"=>"2013-12-07T20:42:09Z", "user"=>"IvorGoodbody", "user_name"=>"Ivor Goodbody", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1762170479/IvorG_PictoPaint_normal.jpg"}
• {"id"=>"468028831023267840", "text"=>"@rafadiazmd Es verdad Rafael; agregaría fin de otro fraude. Adjunto excelente artículo de revisión sobre le tema. http://t.co/n4oW9sIb3E", "created_at"=>"2014-05-18T14:02:23Z", "user"=>"drpablocorral", "user_name"=>"Pablo Corral MD", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1793037549/image_normal.jpg"}
• {"id"=>"468033323538071554", "text"=>"Agregaría fin de otro fraude! Adjunto excelente artículo de revisión via RT @drpablocorral http://t.co/7yJQabi9UM", "created_at"=>"2014-05-18T14:20:14Z", "user"=>"rafadiazmd", "user_name"=>"Rafael Díaz", "user_profile_image"=>"http://pbs.twimg.com/profile_images/441191620772261888/sExRVYT7_normal.jpeg"}

Wikipedia | Further Information

• {"title"=>"Resveratrol", "url"=>"http://en.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2019-02-27T16:57:01Z"}
• {"title"=>"Thomas Szekeres", "url"=>"http://de.wikipedia.org/wiki/Thomas_Szekeres", "timestamp"=>"2018-12-14T12:07:08Z"}
• {"title"=>"Resveratrol", "url"=>"http://es.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2018-11-14T22:44:38Z"}
• {"title"=>"Resveratrol", "url"=>"http://pt.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2018-09-18T20:42:20Z"}
• {"title"=>"白藜芦醇", "url"=>"http://zh.wikipedia.org/wiki/白藜芦醇", "timestamp"=>"2018-04-01T07:18:45Z"}

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/764150"], "description"=>"<p>Recommendations for the use of resveratrol – part 5.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434496, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t005", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_the_use_of_resveratrol_8211_part_5_/434496", "title"=>"Recommendations for the use of resveratrol – part 5.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:14:56"}
• {"files"=>["https://ndownloader.figshare.com/files/764498"], "description"=>"<p>Recommendations for the use of resveratrol – part 2.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434849, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t002", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_the_use_of_resveratrol_8211_part_2_/434849", "title"=>"Recommendations for the use of resveratrol – part 2.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:20:49"}
• {"files"=>["https://ndownloader.figshare.com/files/763962"], "description"=>"<p>The literature search was performed to identify all relevant articles focusing on resveratrol and chemoprevention (A), effect of resveratrol on cardio vascular disease (B), effect of resveratrol obesity and diabetes (C), neuroprotective effect of resveratrol (D) and the anti-inflammatory effect of resveratrol (E). In all five groups, articles with non-english language, review articles and articles showing data from <i>in vitro</i> experiments only are excluded. For chemopreventive effect (A), cardio vascular disease (B), obesity and diabetes (C), also non-chronic animal studies were excluded.</p>", "links"=>[], "tags"=>["systematic"], "article_id"=>434306, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.g001", "stats"=>{"downloads"=>2, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Flow_chart_of_systematic_literature_search_/434306", "title"=>"Flow chart of systematic literature search.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-06-16 01:11:46"}
• {"files"=>["https://ndownloader.figshare.com/files/384345", "https://ndownloader.figshare.com/files/384465", "https://ndownloader.figshare.com/files/384569", "https://ndownloader.figshare.com/files/384653", "https://ndownloader.figshare.com/files/384795"], "description"=>"<div><h3>Background</h3><p>Resveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid recommendations concerning the human intake of resveratrol based on available published scientific data are necessary. Such recommendations were formulated after the Resveratrol 2010 conference, held in September 2010 in Helsingør, Denmark.</p> <h3>Methodology</h3><p>Literature search in databases as PubMed and ISI Web of Science in combination with manual search was used to answer the following five questions: ¹Can resveratrol be recommended in the prevention or treatment of human diseases?; ²Are there observed “side effects” caused by the intake of resveratrol in humans?; ³What is the relevant dose of resveratrol?; ⁴What valid data are available regarding an effect in various species of experimental animals?; ⁵Which relevant (overall) mechanisms of action of resveratrol have been documented?</p> <h3>Conclusions/Significance</h3><p>The overall conclusion is that the published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources. On the other hand, animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials. Finally, we suggest directions for future research in resveratrol regarding its mechanism of action and its safety and toxicology in human subjects.</p> </div>", "links"=>[], "tags"=>["systematic", "recommendations", "resveratrol"], "article_id"=>135877, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0019881.s001", "https://dx.doi.org/10.1371/journal.pone.0019881.s002", "https://dx.doi.org/10.1371/journal.pone.0019881.s003", "https://dx.doi.org/10.1371/journal.pone.0019881.s004", "https://dx.doi.org/10.1371/journal.pone.0019881.s005"], "stats"=>{"downloads"=>117, "page_views"=>40, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/What_Is_New_for_an_Old_Molecule_Systematic_Review_and_Recommendations_on_the_Use_of_Resveratrol/135877", "title"=>"What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2011-06-16 01:37:57"}
• {"files"=>["https://ndownloader.figshare.com/files/764441"], "description"=>"<p>Recommendations for the use of resveratrol – part 3.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434791, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t003", "stats"=>{"downloads"=>7, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_the_use_of_resveratrol_8211_part_3_/434791", "title"=>"Recommendations for the use of resveratrol – part 3.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:19:51"}
• {"files"=>["https://ndownloader.figshare.com/files/764381"], "description"=>"<p>Recommendations for the use of resveratrol – part 1.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434732, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t001", "stats"=>{"downloads"=>3, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_the_use_of_resveratrol_8211_part_1_/434732", "title"=>"Recommendations for the use of resveratrol – part 1.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:18:52"}
• {"files"=>["https://ndownloader.figshare.com/files/764323"], "description"=>"<p>Overall conclusions for the use of resveratrol.</p>", "links"=>[], "tags"=>["conclusions"], "article_id"=>434676, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t006", "stats"=>{"downloads"=>1, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Overall_conclusions_for_the_use_of_resveratrol_/434676", "title"=>"Overall conclusions for the use of resveratrol.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:17:56"}
• {"files"=>["https://ndownloader.figshare.com/files/764266"], "description"=>"<p>Recommendations for research on resveratrol for the coming years.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434614, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t007", "stats"=>{"downloads"=>12, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_research_on_resveratrol_for_the_coming_years_/434614", "title"=>"Recommendations for research on resveratrol for the coming years.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:16:54"}
• {"files"=>["https://ndownloader.figshare.com/files/764202"], "description"=>"<p>Recommendations for the use of resveratrol – part 4.</p>", "links"=>[], "tags"=>["resveratrol"], "article_id"=>434551, "categories"=>["Chemistry", "Science Policy", "Biotechnology", "Cancer", "Medicine"], "users"=>["Ole Vang", "Nihal Ahmad", "Clifton A. Baile", "Joseph A. Baur", "Karen Brown", "Anna Csiszar", "Dipak K. Das", "Dominique Delmas", "Carmem Gottfried", "Hung-Yun Lin", "Qing-Yong Ma", "Partha Mukhopadhyay", "Namasivayam Nalini", "John M. Pezzuto", "Tristan Richard", "Yogeshwer Shukla", "Young-Joon Surh", "Thomas Szekeres", "Tomasz Szkudelski", "Thomas Walle", "Joseph M. Wu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0019881.t004", "stats"=>{"downloads"=>6, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Recommendations_for_the_use_of_resveratrol_8211_part_4_/434551", "title"=>"Recommendations for the use of resveratrol – part 4.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-06-16 01:15:51"}

PMC Usage Stats | Further Information

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F1000Prime