What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
- Publication Date
- June 16, 2011
- Journal
- PLOS ONE
- Authors
- Ole Vang, Nihal Ahmad, Clifton A. Baile, Joseph A. Baur, et al
- Volume
- 6
- Issue
- 6
- Pages
- e19881
- DOI
- https://dx.plos.org/10.1371/journal.pone.0019881
- Publisher URL
- http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0019881
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/21698226
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116821
- Europe PMC
- http://europepmc.org/abstract/MED/21698226
- Web of Science
- 000291734100003
- Scopus
- 79959261445
- Mendeley
- http://www.mendeley.com/research/new-old-molecule-systematic-review-recommendations-resveratrol-2
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Mendeley | Further Information
{"title"=>"What is new for an old molecule? systematic review and recommendations on the use of resveratrol", "type"=>"generic", "authors"=>[{"first_name"=>"Ole", "last_name"=>"Vang", "scopus_author_id"=>"56055987000"}, {"first_name"=>"Nihal", "last_name"=>"Ahmad", "scopus_author_id"=>"7202343847"}, {"first_name"=>"Clifton A.", "last_name"=>"Baile", "scopus_author_id"=>"35309412900"}, {"first_name"=>"Joseph A.", "last_name"=>"Baur", "scopus_author_id"=>"14038740300"}, {"first_name"=>"Karen", "last_name"=>"Brown", "scopus_author_id"=>"7404382777"}, {"first_name"=>"Anna", "last_name"=>"Csiszar", "scopus_author_id"=>"6603855913"}, {"first_name"=>"Dipak K.", "last_name"=>"Das", "scopus_author_id"=>"7402353061"}, {"first_name"=>"Dominique", "last_name"=>"Delmas", "scopus_author_id"=>"6603955122"}, {"first_name"=>"Carmem", "last_name"=>"Gottfried", "scopus_author_id"=>"6701465385"}, {"first_name"=>"Hung Yun", "last_name"=>"Lin", "scopus_author_id"=>"26643131700"}, {"first_name"=>"Qing Yong", "last_name"=>"Ma", "scopus_author_id"=>"8561795900"}, {"first_name"=>"Partha", "last_name"=>"Mukhopadhyay", "scopus_author_id"=>"14825346100"}, {"first_name"=>"Namasivayam", "last_name"=>"Nalini", "scopus_author_id"=>"7004312975"}, {"first_name"=>"John M.", "last_name"=>"Pezzuto", "scopus_author_id"=>"35392643400"}, {"first_name"=>"Tristan", "last_name"=>"Richard", "scopus_author_id"=>"7007044714"}, {"first_name"=>"Yogeshwer", "last_name"=>"Shukla", "scopus_author_id"=>"7005216145"}, {"first_name"=>"Young Joon", "last_name"=>"Surh", "scopus_author_id"=>"7006078097"}, {"first_name"=>"Thomas", "last_name"=>"Szekeres", "scopus_author_id"=>"7004356027"}, {"first_name"=>"Tomasz", "last_name"=>"Szkudelski", "scopus_author_id"=>"6701674299"}, {"first_name"=>"Thomas", "last_name"=>"Walle", "scopus_author_id"=>"7005995905"}, {"first_name"=>"Joseph M.", "last_name"=>"Wu", "scopus_author_id"=>"7409255188"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-79959261445", "sgr"=>"79959261445", "issn"=>"19326203", "doi"=>"10.1371/journal.pone.0019881", "pmid"=>"21698226", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)", "pui"=>"361966415"}, "id"=>"b920f11d-f4c2-3845-8478-ed717297ee2c", "abstract"=>"<sec> <title>Background</title> <p>Resveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid recommendations concerning the human intake of resveratrol based on available published scientific data are necessary. Such recommendations were formulated after the Resveratrol 2010 conference, held in September 2010 in Helsingør, Denmark.</p> </sec> <sec> <title>Methodology</title> <p>Literature search in databases as PubMed and ISI Web of Science in combination with manual search was used to answer the following five questions: <sup>1</sup>Can resveratrol be recommended in the prevention or treatment of human diseases?; <sup>2</sup>Are there observed “side effects” caused by the intake of resveratrol in humans?; <sup>3</sup>What is the relevant dose of resveratrol?; <sup>4</sup>What valid data are available regarding an effect in various species of experimental animals?; <sup>5</sup>Which relevant (overall) mechanisms of action of resveratrol have been documented?</p> </sec> <sec> <title>Conclusions/Significance</title> <p>The overall conclusion is that the published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources. On the other hand, animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials. Finally, we suggest directions for future research in resveratrol regarding its mechanism of action and its safety and toxicology in human subjects.</p> </sec>", "link"=>"http://www.mendeley.com/research/new-old-molecule-systematic-review-recommendations-resveratrol-2", "reader_count"=>197, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>12, "Researcher"=>29, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>10, "Student > Master"=>38, "Other"=>12, "Student > Bachelor"=>32, "Lecturer > Senior Lecturer"=>1, "Professor"=>8}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>12, "Researcher"=>29, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>10, "Student > Master"=>38, "Other"=>12, "Student > Bachelor"=>32, "Lecturer > Senior Lecturer"=>1, "Professor"=>8}, "reader_count_by_subject_area"=>{"Unspecified"=>10, "Agricultural and Biological Sciences"=>75, "Philosophy"=>1, "Business, Management and Accounting"=>1, "Chemical Engineering"=>2, "Chemistry"=>14, "Engineering"=>3, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>17, "Nursing and Health Professions"=>3, "Medicine and Dentistry"=>51, "Neuroscience"=>9, "Sports and Recreations"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>5, "Physics and Astronomy"=>1, "Psychology"=>1, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>51}, "Social Sciences"=>{"Social Sciences"=>2}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>1}, "Unspecified"=>{"Unspecified"=>10}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>5}, "Chemical Engineering"=>{"Chemical Engineering"=>2}, "Engineering"=>{"Engineering"=>3}, "Chemistry"=>{"Chemistry"=>14}, "Neuroscience"=>{"Neuroscience"=>9}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>75}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>17}, "Philosophy"=>{"Philosophy"=>1}}, "reader_count_by_country"=>{"Lebanon"=>1, "Canada"=>1, "Netherlands"=>2, "Czech Republic"=>1, "United States"=>5, "Japan"=>1, "Brazil"=>3, "Italy"=>3, "United Kingdom"=>1, "Malaysia"=>1, "India"=>2}, "group_count"=>6}CrossRef
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- http://doi.org/10.1016/j.tifs.2014.05.003
- http://doi.org/10.1002/mnfr.201300913
- http://doi.org/10.1016/j.biochi.2013.07.002
- http://doi.org/10.1016/j.fct.2013.07.021
- http://doi.org/10.1016/j.jff.2020.104090
- http://doi.org/10.1179/1351000214Y.0000000087
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- http://doi.org/10.1016/j.yexcr.2015.01.013
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PubMed Central | Further Information
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Scopus | Further Information
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- {"referral"=>"http://www.quackwatch.org/01QuackeryRelatedTopics/DSH/resveratrol.html", "language"=>"English", "title"=>"Resveratrol: Don't Buy the Hype", "type"=>"Blog", "publication"=>"", "published_on"=>"", "link_state"=>""}
- {"referral"=>"http://www.resveratrol2012.eu/index.php/Resveratrol-2012/2/0/", "language"=>"", "title"=>"Resveratrol 2012: Resveratol 2012", "type"=>"Blog", "publication"=>"", "published_on"=>"", "link_state"=>""}
- {"referral"=>"http://www.quackwatch.com/01QuackeryRelatedTopics/DSH/resveratrol.html", "language"=>"English", "title"=>"Resveratrol: Don't Buy the Hype", "type"=>"Blog", "publication"=>"", "published_on"=>"", "link_state"=>""}
- {"referral"=>"http://www.ettoday.net/news/20140310/332487.htm", "language"=>"", "title"=>"紅酒及葡萄籽的白藜蘆醇(resveratrol)有沒有效? | ETtoday名家新聞 | ETtoday 新聞雲", "type"=>"Blog", "publication"=>"ETtoday 新聞雲", "published_on"=>"", "link_state"=>""}
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- {"id"=>"371711959957123072", "text"=>"@COPDdoc @BootsSkincare Evidence for use of resveratrol as oral supplement is not flattering http://t.co/kQxzHa1CGt", "created_at"=>"2013-08-25T19:13:31Z", "user"=>"pash22", "user_name"=>"Ash Paul", "user_profile_image"=>"http://a0.twimg.com/profile_images/3295856896/66ab958422d28c521d0143bddbb90233_normal.jpeg"}
- {"id"=>"377843030725652481", "text"=>"\"Evidence does not justify recommendation of resveratrol for humans,beyond what can be obtained from dietary sources\" http://t.co/3sYcKwJytE", "created_at"=>"2013-09-11T17:16:13Z", "user"=>"IvorGoodbody", "user_name"=>"Ivor Goodbody", "user_profile_image"=>"http://a0.twimg.com/profile_images/1762170479/IvorG_PictoPaint_normal.jpg"}
- {"id"=>"409422600763228160", "text"=>"#Resveratrol evidence review: no proof of human benefits but promising anti-#cancer/#HeartDisease results in animals http://t.co/3sYcKwJytE", "created_at"=>"2013-12-07T20:42:09Z", "user"=>"IvorGoodbody", "user_name"=>"Ivor Goodbody", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1762170479/IvorG_PictoPaint_normal.jpg"}
- {"id"=>"468028831023267840", "text"=>"@rafadiazmd Es verdad Rafael; agregaría fin de otro fraude. Adjunto excelente artículo de revisión sobre le tema. http://t.co/n4oW9sIb3E", "created_at"=>"2014-05-18T14:02:23Z", "user"=>"drpablocorral", "user_name"=>"Pablo Corral MD", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1793037549/image_normal.jpg"}
- {"id"=>"468033323538071554", "text"=>"Agregaría fin de otro fraude! Adjunto excelente artículo de revisión via RT @drpablocorral http://t.co/7yJQabi9UM", "created_at"=>"2014-05-18T14:20:14Z", "user"=>"rafadiazmd", "user_name"=>"Rafael Díaz", "user_profile_image"=>"http://pbs.twimg.com/profile_images/441191620772261888/sExRVYT7_normal.jpeg"}
Wikipedia | Further Information
- {"title"=>"Resveratrol", "url"=>"http://en.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2019-02-27T16:57:01Z"}
- {"title"=>"Thomas Szekeres", "url"=>"http://de.wikipedia.org/wiki/Thomas_Szekeres", "timestamp"=>"2018-12-14T12:07:08Z"}
- {"title"=>"Resveratrol", "url"=>"http://es.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2018-11-14T22:44:38Z"}
- {"title"=>"Resveratrol", "url"=>"http://pt.wikipedia.org/wiki/Resveratrol", "timestamp"=>"2018-09-18T20:42:20Z"}
- {"title"=>"白藜芦醇", "url"=>"http://zh.wikipedia.org/wiki/白藜芦醇", "timestamp"=>"2018-04-01T07:18:45Z"}
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PMC Usage Stats | Further Information
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Relative Metric
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