The Sedative Effect of Non-Alcoholic Beer in Healthy Female Nurses
Publication Date
July 18, 2012
Journal
PLOS ONE
Authors
Lourdes Franco, Cristina Sánchez, Rafael Bravo, Ana B. Rodríguez, et al
Volume
7
Issue
7
Pages
e37290
DOI
https://dx.plos.org/10.1371/journal.pone.0037290
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0037290
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/22815680
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399866
Europe PMC
http://europepmc.org/abstract/MED/22815680
Web of Science
000306548900003
Scopus
84864008621
Mendeley
http://www.mendeley.com/research/sedative-effect-nonalcoholic-beer-healthy-female-nurses
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Mendeley | Further Information

{"title"=>"The sedative effect of non-alcoholic beer in healthy female nurses", "type"=>"journal", "authors"=>[{"first_name"=>"Lourdes", "last_name"=>"Franco", "scopus_author_id"=>"12772713100"}, {"first_name"=>"Cristina", "last_name"=>"Sánchez", "scopus_author_id"=>"36167057200"}, {"first_name"=>"Rafael", "last_name"=>"Bravo", "scopus_author_id"=>"37116505800"}, {"first_name"=>"Ana B.", "last_name"=>"Rodríguez", "scopus_author_id"=>"7403543061"}, {"first_name"=>"Carmen", "last_name"=>"Barriga", "scopus_author_id"=>"7004318909"}, {"first_name"=>"Eulalia", "last_name"=>"Romero", "scopus_author_id"=>"57197926026"}, {"first_name"=>"Javier", "last_name"=>"Cubero", "scopus_author_id"=>"9245684900"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "pui"=>"365274715", "pmid"=>"22815680", "doi"=>"10.1371/journal.pone.0037290", "sgr"=>"84864008621", "scopus"=>"2-s2.0-84864008621"}, "id"=>"924fc232-13ce-370f-bfdc-dc303bedb246", "abstract"=>"INTRODUCTION: The hop (Humulus lupulus L.), a component of beer, is a sedative plant whose pharmacological activity is principally due to its bitter resins, in particular to the α-acid degradation product 2-methyl-3-buten-2-ol. The mechanism of action of hop resin consists of raising the levels of the neurotransmitter γ-aminobutyric acid (GABA), an inhibitory neurotransmitter acting in the central nervous system (CNS).\\n\\nOBJECTIVES: To analyze the sedative effect of hops as a component of non-alcoholic beer on the sleep/wake rhythm in a work-stressed population.\\n\\nMETHODS: The experiment was conducted with healthy female nurses (n = 17) working rotating and/or night shifts. Overnight sleep and chronobiological parameters were assessed by actigraphy (Actiwatch®) after moderate ingestion of non-alcoholic beer containing hops (333 ml with 0.0% alcohol) with supper for 14 days (treatment). Data were obtained in comparison with her own control group without consumption of beer during supper.\\n\\nRESULTS: Actigraphy results demonstrated improvement of night sleep quality as regards the most important parameters: Sleep Latency diminished (p≤0.05) in the Treatment group (12.01±1.19 min) when compared to the Control group (20.50±4.21 min), as also did Total Activity (p≤0.05; Treatment group = 5284.78±836.99 activity pulses vs Control = 7258.78±898.89 activity pulses). In addition, anxiety as indexed by the State-Trait Anxiety Inventory (STAI) decreased in the Treatment group (State Anxiety 18.09±3.8 vs Control 20.69±2.14).\\n\\nCONCLUSION: The moderate consumption of non-alcoholic beer will favour night-time rest, due in particular to its hop components, in addition to its other confirmed benefits for the organism.", "link"=>"http://www.mendeley.com/research/sedative-effect-nonalcoholic-beer-healthy-female-nurses", "reader_count"=>49, "reader_count_by_academic_status"=>{"Unspecified"=>4, "Professor > Associate Professor"=>2, "Researcher"=>14, "Student > Ph. D. Student"=>9, "Other"=>3, "Student > Master"=>6, "Student > Bachelor"=>10, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>4, "Professor > Associate Professor"=>2, "Researcher"=>14, "Student > Ph. D. Student"=>9, "Other"=>3, "Student > Master"=>6, "Student > Bachelor"=>10, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>7, "Engineering"=>1, "Nursing and Health Professions"=>3, "Biochemistry, Genetics and Molecular Biology"=>2, "Agricultural and Biological Sciences"=>19, "Medicine and Dentistry"=>7, "Arts and Humanities"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Chemistry"=>5, "Psychology"=>2, "Economics, Econometrics and Finance"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>7}, "Chemistry"=>{"Chemistry"=>5}, "Psychology"=>{"Psychology"=>2}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>19}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>7}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"Japan"=>1, "France"=>1}, "group_count"=>3}

Scopus | Further Information

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Relative Metric

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