CiteULike | Further Information

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Mendeley | Further Information

{"title"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways", "type"=>"journal", "authors"=>[{"first_name"=>"Manoj K.", "last_name"=>"Bhasin", "scopus_author_id"=>"8417767500"}, {"first_name"=>"Jeffery A.", "last_name"=>"Dusek", "scopus_author_id"=>"7103231869"}, {"first_name"=>"Bei Hung", "last_name"=>"Chang", "scopus_author_id"=>"7402600517"}, {"first_name"=>"Marie G.", "last_name"=>"Joseph", "scopus_author_id"=>"57198135433"}, {"first_name"=>"John W.", "last_name"=>"Denninger", "scopus_author_id"=>"7801472801"}, {"first_name"=>"Gregory L.", "last_name"=>"Fricchione", "scopus_author_id"=>"7006886559"}, {"first_name"=>"Herbert", "last_name"=>"Benson", "scopus_author_id"=>"7103376700"}, {"first_name"=>"Towia A.", "last_name"=>"Libermann", "scopus_author_id"=>"7006148994"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"368847432", "issn"=>"19326203", "isbn"=>"1932-6203", "doi"=>"10.1371/journal.pone.0062817", "scopus"=>"2-s2.0-84877045019", "pmid"=>"23650531", "sgr"=>"84877045019"}, "id"=>"56648117-74fd-3360-80bd-e8615140e2c0", "abstract"=>"The relaxation response (RR) is the counterpart of the stress response. Millennia-old practices evoking the RR include meditation, yoga and repetitive prayer. Although RR elicitation is an effective therapeutic intervention that counteracts the adverse clinical effects of stress in disorders including hypertension, anxiety, insomnia and aging, the underlying molecular mechanisms that explain these clinical benefits remain undetermined. To assess rapid time-dependent (temporal) genomic changes during one session of RR practice among healthy practitioners with years of RR practice and also in novices before and after 8 weeks of RR training, we measured the transcriptome in peripheral blood prior to, immediately after, and 15 minutes after listening to an RR-eliciting or a health education CD. Both short-term and long-term practitioners evoked significant temporal gene expression changes with greater significance in the latter as compared to novices. RR practice enhanced expression of genes associated with energy metabolism, mitochondrial function, insulin secretion and telomere maintenance, and reduced expression of genes linked to inflammatory response and stress-related pathways. Interactive network analyses of RR-affected pathways identified mitochondrial ATP synthase and insulin (INS) as top upregulated critical molecules (focus hubs) and NF-κB pathway genes as top downregulated focus hubs. Our results for the first time indicate that RR elicitation, particularly after long-term practice, may evoke its downstream health benefits by improving mitochondrial energy production and utilization and thus promoting mitochondrial resiliency through upregulation of ATPase and insulin function. Mitochondrial resiliency might also be promoted by RR-induced downregulation of NF-κB-associated upstream and downstream targets that mitigates stress.", "link"=>"http://www.mendeley.com/research/relaxation-response-induces-temporal-transcriptome-changes-energy-metabolism-insulin-secretion-infla-2", "reader_count"=>43, "reader_count_by_academic_status"=>{"Unspecified"=>4, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>4, "Researcher"=>9, "Student > Ph. D. Student"=>5, "Student > Postgraduate"=>5, "Student > Master"=>5, "Other"=>4, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1, "Professor"=>1, "Librarian"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>4, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>4, "Researcher"=>9, "Student > Ph. D. 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"annotationUri"=>"info:doi/10.1371/reply/1cd1044d-6782-4642-8899-d3df784478e9", "title"=>"RE: RE: Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: Relaxnews \nTitle: “Meditation may help reduce inflammation, control blood sugar”\nhttp://www.thenewage.co.za/94776-12-53-Meditation_may_help_reduce_inflammation_control_blood_sugar\n\n\nPublication: Relaxnews \nTitle: “Meditation may help reduce inflammation, control blood sugar”\nhttp://www.boston.com/lifestyle/health/2013/05/06/meditation-may-help-reduce-inflammation-control-blood-sugar/WT8t71Pk2WyLzpmuBm7wFI/story.html\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article. \n", "isRemoved"=>false, "created"=>"2013-05-13T16:24:18Z", "lastModified"=>"2013-05-13T16:24:18Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2013-05-17T22:58:52Z", "replies"=>[{"type"=>"REPLY", "parentID"=>65821, "annotationUri"=>"info:doi/10.1371/reply/9eaff399-33d9-4f46-a743-aaf0d57af1ca", "title"=>"RE: RE: RE: Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: PR Web \nTitle: “Bel Marra Health Reports on a New Study Revealing a Natural Remedy for Hypertension, Insomnia, and Aging”\nhttp://www.prweb.com/releases/belmarrahealth/generalhealth/prweb10741738.htm\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.", "isRemoved"=>false, "created"=>"2013-05-17T22:58:52Z", "lastModified"=>"2013-05-17T22:58:52Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2013-05-17T22:58:52Z", "replies"=>[]}]}]}, {"type"=>"REPLY", "parentID"=>65359, "annotationUri"=>"info:doi/10.1371/reply/4faa0fea-f8c8-48d8-b269-57f6b1fd39a5", "title"=>"RE: Media Coverage of This Article", "body"=>"Title: \"Yoga Isn't Just Good For Your Mind, It's Good For Your Genes\"\nhttp://greatist.com/happiness/yoga-meditation-change-genes-050313?utm_source=Sailthru&utm_medium=email&utm_term=Greatist+Daily&utm_campaign=Stress+and+Productivity", "isRemoved"=>false, "created"=>"2013-05-30T18:17:53Z", "lastModified"=>"2013-05-30T18:17:53Z", "creator"=>{"userId"=>"342263"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>4, "mostRecentActivity"=>"2013-09-03T23:16:33Z", "replies"=>[{"type"=>"REPLY", "parentID"=>66535, "annotationUri"=>"info:doi/10.1371/reply/31a31961-60a4-4fd6-95ad-dec58d548357", "title"=>" Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: Mark's Daily Apple \nTitle: “Weekend Link Love - Edition 241 | Mark's Daily Apple”\nhttp://www.marksdailyapple.com/weekend-link-love-241/\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article. \n", "isRemoved"=>false, "created"=>"2013-07-29T20:13:51Z", "lastModified"=>"2013-07-29T20:13:51Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>3, "mostRecentActivity"=>"2013-09-03T23:16:33Z", "replies"=>[{"type"=>"REPLY", "parentID"=>69225, "annotationUri"=>"info:doi/10.1371/reply/b4797974-ed88-49e7-813e-11edf3a988ea", "title"=>" Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: Massachusetts General Hospital press release \nTitle: “Study identifies genes, pathways altered during relaxation response practice - Massachusetts General Hospital, Boston, MA”\nhttp://www.massgeneral.org/about/pressrelease.aspx?id=1583\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article. \n", "isRemoved"=>false, "created"=>"2013-07-29T20:14:23Z", "lastModified"=>"2013-07-29T20:14:23Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>2, "mostRecentActivity"=>"2013-09-03T23:16:33Z", "replies"=>[{"type"=>"REPLY", "parentID"=>69227, "annotationUri"=>"info:doi/10.1371/reply/f75ff71e-d033-45c0-af54-f3d8503ae785", "title"=>" Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: Mark's Daily Apple \nTitle: “Weekend Link Love - Edition 241 | Mark's Daily Apple”\nhttp://www.marksdailyapple.com/weekend-link-love-241/\n\nPublication: Massachusetts General Hospital press release \nTitle: “Study identifies genes, pathways altered during relaxation response practice - Massachusetts General Hospital, Boston, MA”\nhttp://www.massgeneral.org/about/pressrelease.aspx?id=1583\n\nPublication: Nooga \nTitle: “Waking up: Study shows mindfulness can offer health benefits | Nooga.com”\nhttp://www.nooga.com/162705/waking-up-study-shows-mindfulness-can-offer-health-benefits/\n\n\nPublication: The Atlantic \nTitle: “Study: How Yoga Alters Genes - Lindsay Abrams - The Atlantic”\nhttp://www.theatlantic.com/health/archive/2013/05/how-yoga-alters-genes/275488/\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article. \n", "isRemoved"=>false, "created"=>"2013-08-05T22:46:22Z", "lastModified"=>"2013-08-05T22:46:22Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2013-09-03T23:16:33Z", "replies"=>[{"type"=>"REPLY", "parentID"=>69681, "annotationUri"=>"info:doi/10.1371/reply/6117e2de-bd5d-4c13-b906-a06d46aabfa7", "title"=>" Media Coverage of This Article", "body"=>"The following article represents some of the media coverage that has occurred for this paper:\n\nPublication: North Jersey \nTitle: “Health care profession is increasingly adopting meditation : page 1 - NorthJersey.com”\nhttp://www.northjersey.com/news/222032201_Health_care_profession_is_increasingly_adopting_meditation.html?c=y&page=1\n\nIf you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article. \n", "isRemoved"=>false, "created"=>"2013-09-03T23:16:33Z", "lastModified"=>"2013-09-03T23:16:33Z", "creator"=>{"userId"=>"80539"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"PLOS ONE Staff"}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2013-09-03T23:16:33Z", "replies"=>[]}]}]}]}]}]}
• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/cb933c53-203a-41ab-9739-dc0385d34d4f", "title"=>"Comment on the introduction", "body"=>"I just wanted to point out that, in the introduction, Vipassana is refered to as a form of Yoga and it isn't: \"different practices of yoga (e.g., Vipassana and Kundalini)\" Vipassana is a Buddhist term referring to insight and is often used to mean insight meditation, a form of mindfulness meditation.", "isRemoved"=>false, "created"=>"2013-05-07T17:50:04Z", "lastModified"=>"2013-05-07T17:50:04Z", "creator"=>{"userId"=>"335759"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2013-05-07T17:50:04Z", "replies"=>[]}
• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/47a8de86-a0d9-484f-8a5f-b0e9c78181e7", "title"=>"Difference in breathing profile, a potential confounding factor", "body"=>"The gene expression profile may be influenced by breathing before, ongoing and after the relaxation response (RR) practice, especiallythat the authors found some associaitons with energy metabolism etc. In addition, participants' informaiton such as age, gender BMI etc is of lack.", "isRemoved"=>false, "created"=>"2013-05-17T15:16:37Z", "lastModified"=>"2013-05-17T15:16:37Z", "creator"=>{"userId"=>"300081"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0062817", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2013-05-17T15:16:37Z", "replies"=>[]}

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• {"id"=>"329717603096469504", "text"=>"Relaxation response changes expression of genes involved in immune function, telomeres, more. But do changes last? http://t.co/qcnZofBZYi", "created_at"=>"2013-05-01T22:02:57Z", "user"=>"sxbegle", "user_name"=>"sharon begley", "user_profile_image"=>"http://a0.twimg.com/profile_images/2602799189/pfqikfot0pbywuygdzfs_normal.jpeg"}
• {"id"=>"329986534390525952", "text"=>"@gorskon If it helps, this is the PlosOne paper - http://t.co/rP5Z6ec7cb", "created_at"=>"2013-05-02T15:51:35Z", "user"=>"Unity_MoT", "user_name"=>"Unity", "user_profile_image"=>"http://a0.twimg.com/profile_images/525625618/branding_normal.jpg"}
• {"id"=>"330000733401411586", "text"=>"Primer estudio q muestra el efecto de la meditación sobre el metabolismo http://t.co/zW3xf2oNVc", "created_at"=>"2013-05-02T16:48:00Z", "user"=>"baldiricardo", "user_name"=>" Ricardo Baldi", "user_profile_image"=>"http://a0.twimg.com/profile_images/2562117319/81se26c1omfznhxoko33_normal.jpeg"}
• {"id"=>"330001053246427137", "text"=>"La respuesta metabólica a la meditación es la opuesta al stress http://t.co/zW3xf2oNVc", "created_at"=>"2013-05-02T16:49:16Z", "user"=>"baldiricardo", "user_name"=>" Ricardo Baldi", "user_profile_image"=>"http://a0.twimg.com/profile_images/2562117319/81se26c1omfznhxoko33_normal.jpeg"}
• {"id"=>"330014790669959169", "text"=>"it's official, meditation influences metabolism, immune response #news\nhttp://t.co/6XYmG5dtnS", "created_at"=>"2013-05-02T17:43:52Z", "user"=>"fkliron", "user_name"=>"F", "user_profile_image"=>"http://a0.twimg.com/profile_images/3530301087/fc86a9dff018abd5b1275cf26d7481a1_normal.png"}
• {"id"=>"330017245428342785", "text"=>"Meditatie zou genen voor goede gezondheid activeren. http://t.co/jT4q1StvRR Boeiend, maar eerst wachten op bevestiging door ander onderzoek.", "created_at"=>"2013-05-02T17:53:37Z", "user"=>"MarkNelissen", "user_name"=>"Mark Nelissen", "user_profile_image"=>"http://a0.twimg.com/profile_images/1854899853/mark_nelissen_normal.jpg"}
• {"id"=>"330032888982695936", "text"=>"#Meditation improves mitochondrial #energy production and utilization and thus promoting mitochondrial resiliency http://t.co/Y5wTkphFkg", "created_at"=>"2013-05-02T18:55:47Z", "user"=>"meatheadscience", "user_name"=>"Dr. Meat", "user_profile_image"=>"http://a0.twimg.com/profile_images/3113036817/b5034bea972f422485b2e3b722d5ca77_normal.jpeg"}
• {"id"=>"330045251727282177", "text"=>"Relaxation Response Induces Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways http://t.co/GfUX3zfXbF", "created_at"=>"2013-05-02T19:44:54Z", "user"=>"sonalkiss", "user_name"=>"Sonalkiss", "user_profile_image"=>"http://a0.twimg.com/profile_images/2884716052/e241b6cbf927d2234fa6181d1608d596_normal.png"}
• {"id"=>"330045317514919936", "text"=>"RT @sonalkiss: Relaxation Response Induces Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways http://t.co/GfUX3zfXbF", "created_at"=>"2013-05-02T19:45:10Z", "user"=>"jwkerr", "user_name"=>"Jonathan Kerr", "user_profile_image"=>"http://a0.twimg.com/profile_images/1505468585/184109_10150261770343461_548173460_7666616_7979687_n_normal.jpg"}
• {"id"=>"330073142091448321", "text"=>"RT @MarkNelissen: Meditatie zou genen voor goede gezondheid activeren. http://t.co/jT4q1StvRR Boeiend, maar eerst wachten op bevestiging do…", "created_at"=>"2013-05-02T21:35:44Z", "user"=>"ProfDirkAvonts", "user_name"=>"Prof. Dirk Avonts", "user_profile_image"=>"http://a0.twimg.com/profile_images/2875065316/b6e286a4fe6c6d3407eede4bc8a24d63_normal.png"}
• {"id"=>"330073987021426690", "text"=>"@PLOSONE : relax. resp. (yoga, medit. etc) modifies genetic regulation of  metabolism, inflammation, telomere maint http://t.co/euHp6jfL57", "created_at"=>"2013-05-02T21:39:05Z", "user"=>"randy_ro", "user_name"=>"Randy", "user_profile_image"=>"http://a0.twimg.com/profile_images/3339217468/992b699ec34d03c7069e7005b79bc6e8_normal.jpeg"}
• {"id"=>"330112457743949824", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and... http://t.co/h62bzQzkqP", "created_at"=>"2013-05-03T00:11:57Z", "user"=>"lvidaver", "user_name"=>"lvidaver", "user_profile_image"=>"http://a0.twimg.com/profile_images/1660919129/image_normal.jpg"}
• {"id"=>"330138678250831872", "text"=>"Another reason to go to yoga @yveu @aislinnmacphail #PLOSONE: Relaxation Response Induces Transcriptome Changes http://t.co/eS47B2Yy0f", "created_at"=>"2013-05-03T01:56:09Z", "user"=>"CeilsMac", "user_name"=>"Ceilidh MacPhail", "user_profile_image"=>"http://a0.twimg.com/profile_images/3359683465/9e97c6c5fc4ef010fd36c6f530b8c00d_normal.jpeg"}
• {"id"=>"330165163804213250", "text"=>"@notaslimboy @PastorGilbertL Etapi di Jurnal ini http://t.co/UVUJYXBPL5 Yoga meningkatkan metabolisme & menurunkan inflamasi :)", "created_at"=>"2013-05-03T03:41:23Z", "user"=>"kamentrader", "user_name"=>"Prasdianto", "user_profile_image"=>"http://a0.twimg.com/profile_images/3295278137/a4f0d631cd60dfe4844668be99837045_normal.jpeg"}
• {"id"=>"330194266607460352", "text"=>"@DanielLtobing Ini jurnalnya bang Daniel http://t.co/UVUJYXBPL5 lumayan dibaca sambil nunggu instruktur Yoga :)", "created_at"=>"2013-05-03T05:37:02Z", "user"=>"kamentrader", "user_name"=>"Prasdianto", "user_profile_image"=>"http://a0.twimg.com/profile_images/3295278137/a4f0d631cd60dfe4844668be99837045_normal.jpeg"}
• {"id"=>"330237397856043008", "text"=>"Short-term effect of relaxation techniques on gene expressions: http://t.co/yFrrGzhavJ #meditation #yoga #health", "created_at"=>"2013-05-03T08:28:25Z", "user"=>"VPInkila", "user_name"=>"Ville-Pekka Inkilä", "user_profile_image"=>"http://a0.twimg.com/profile_images/2759201145/b8a7151b13ac0a581283b963d9e93fe2_normal.png"}
• {"id"=>"330248021558304768", "text"=>"Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacarthur", "created_at"=>"2013-05-03T09:10:38Z", "user"=>"matthewherper", "user_name"=>"Matthew Herper", "user_profile_image"=>"http://a0.twimg.com/profile_images/249031463/herperhead_normal.jpg"}
• {"id"=>"330248254258298880", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T09:11:34Z", "user"=>"AdamGDunn", "user_name"=>"Adam Dunn", "user_profile_image"=>"http://a0.twimg.com/profile_images/3454894465/4097b94c66c76f84526662cb021c7639_normal.jpeg"}
• {"id"=>"330252531101999105", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T09:28:33Z", "user"=>"theredwitch", "user_name"=>"The Red Witch", "user_profile_image"=>"http://a0.twimg.com/profile_images/2990721521/185496ef7ac0754674b1e9ef97934683_normal.jpeg"}
• {"id"=>"330252875638898689", "text"=>"Meditation genetically beneficial:Induces Temporal Transcriptome, Energy Metabolism, Insulin Secretion, Inflammation\nhttp://t.co/Ovczbg3OIE", "created_at"=>"2013-05-03T09:29:56Z", "user"=>"JoeRoganExp", "user_name"=>"Joe Rogan Experience", "user_profile_image"=>"http://a0.twimg.com/profile_images/1607301887/269599_241711362522623_241711025855990_1004942_3168486_n_normal.jpg"}
• {"id"=>"330255397111865344", "text"=>"\"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion...\" http://t.co/pYMnkmHd3j #PLOSONE", "created_at"=>"2013-05-03T09:39:57Z", "user"=>"crc8", "user_name"=>"crc", "user_profile_image"=>"http://a0.twimg.com/profile_images/57981730/elephant_artist_normal.jpg"}
• {"id"=>"330267263154405377", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T10:27:06Z", "user"=>"dgmacarthur", "user_name"=>"Daniel MacArthur", "user_profile_image"=>"http://a0.twimg.com/profile_images/1379367446/macarthur_olduvai_profile_cropped_normal.jpg"}
• {"id"=>"330267385045073920", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T10:27:35Z", "user"=>"angela_sheard", "user_name"=>"Angela Sheard", "user_profile_image"=>"http://a0.twimg.com/profile_images/3458592847/3957c54d5c35b97a2cc72762d55ca56d_normal.jpeg"}
• {"id"=>"330267387733610497", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secr http://t.co/IRlW6ZsJo7", "created_at"=>"2013-05-03T10:27:35Z", "user"=>"BASJ4", "user_name"=>"BASJ network", "user_profile_image"=>"http://a0.twimg.com/profile_images/3211290040/6e3ef7f0e023d46a483ec0a2cba04e82_normal.jpeg"}
• {"id"=>"330274463071473664", "text"=>"RT @matthewherper Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/XntCDbKueP cc @dgmacarthur", "created_at"=>"2013-05-03T10:55:42Z", "user"=>"siobhannyc", "user_name"=>"Siobhan O'Connor", "user_profile_image"=>"http://a0.twimg.com/profile_images/2305545033/69i0s9rms4byjp2kzaj8_normal.png"}
• {"id"=>"330278647363670017", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T11:12:20Z", "user"=>"sirihgading", "user_name"=>"Bakawali", "user_profile_image"=>"http://a0.twimg.com/profile_images/3390067579/a60160a45db84f1940bc84adaba4601a_normal.jpeg"}
• {"id"=>"330280391032332289", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Infl http://t.co/fEyXw5SUmW", "created_at"=>"2013-05-03T11:19:16Z", "user"=>"drbachinsky", "user_name"=>"David R. Bachinsky", "user_profile_image"=>"http://a0.twimg.com/profile_images/1415439640/6822_1147392528923_1350846122_30401298_8082523_n_normal.jpg"}
• {"id"=>"330280544195706880", "text"=>"Long-term #yoga / #meditation improve mitochondrial energy production/utilization and mitigate stress/inflammation http://t.co/RDYp8bNqho", "created_at"=>"2013-05-03T11:19:52Z", "user"=>"Sonia_Kang", "user_name"=>"Sonia Kang", "user_profile_image"=>"http://a0.twimg.com/profile_images/3074036979/fd2fe8213741c727c2791bba3d944b17_normal.jpeg"}
• {"id"=>"330280669815119873", "text"=>"Long-term #yoga / #meditation improve mitochondrial energy production/utilization and mitigate #stress/inflammation http://t.co/RDYp8bNqho …", "created_at"=>"2013-05-03T11:20:22Z", "user"=>"Sonia_Kang", "user_name"=>"Sonia Kang", "user_profile_image"=>"http://a0.twimg.com/profile_images/3074036979/fd2fe8213741c727c2791bba3d944b17_normal.jpeg"}
• {"id"=>"330285859117072384", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T11:40:59Z", "user"=>"SCzarnomska", "user_name"=>"Sylwia Czarnomska", "user_profile_image"=>"http://a0.twimg.com/profile_images/3215795750/2e4766924417142eac1cf61e0e04b81a_normal.jpeg"}
• {"id"=>"330302809738182656", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T12:48:21Z", "user"=>"tpage4screening", "user_name"=>"Tricia Page", "user_profile_image"=>"http://a0.twimg.com/profile_images/3568690286/c0b15f8dde0b57693aea917d93f0faf4_normal.jpeg"}
• {"id"=>"330336395572948995", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion.. @andrewpbentley http://t.co/5LxVEaboJa", "created_at"=>"2013-05-03T15:01:48Z", "user"=>"ladyjsky", "user_name"=>"Anna Q.", "user_profile_image"=>"http://a0.twimg.com/profile_images/2159068129/1335185086339_normal.jpg"}
• {"id"=>"330346467673911296", "text"=>"RT @matthewherper: Really? Comments please! Meditation/prayer change gene expression, insulin response http://t.co/mfnk6oPEmc cc: @dgmacar…", "created_at"=>"2013-05-03T15:41:50Z", "user"=>"rkmeduri", "user_name"=>"RK Meduri", "user_profile_image"=>"http://a0.twimg.com/profile_images/3221512356/3d1e3177a8ef79eaea4dc9ef825f19b6_normal.jpeg"}
• {"id"=>"330358306587684866", "text"=>"http://t.co/lkN4knHJj2", "created_at"=>"2013-05-03T16:28:52Z", "user"=>"voog", "user_name"=>"ana clara voog", "user_profile_image"=>"http://a0.twimg.com/profile_images/49169032/13584_normal.jpg"}
• {"id"=>"330363663242375169", "text"=>"Meditation has been killing it lately: http://t.co/Z6CPbgiQTQ (via @embodiedsacred)", "created_at"=>"2013-05-03T16:50:09Z", "user"=>"Kalieezchild", "user_name"=>"Jody Radzik", "user_profile_image"=>"http://a0.twimg.com/profile_images/670654098/jody_normal.jpg"}
• {"id"=>"330364066528894976", "text"=>"RT @Kalieezchild: Meditation has been killing it lately: http://t.co/Z6CPbgiQTQ (via @embodiedsacred)", "created_at"=>"2013-05-03T16:51:45Z", "user"=>"earwulf", "user_name"=>"earwulf", "user_profile_image"=>"http://a0.twimg.com/profile_images/273063105/twit_normal.jpg"}
• {"id"=>"330364918547234818", "text"=>"RT @Kalieezchild: Meditation has been killing it lately: http://t.co/Z6CPbgiQTQ (via @embodiedsacred)", "created_at"=>"2013-05-03T16:55:09Z", "user"=>"BeyondMeds", "user_name"=>"Monica ", "user_profile_image"=>"http://a0.twimg.com/profile_images/3319669726/92d6468a1d736bbed222eb0044c6b183_normal.jpeg"}
• {"id"=>"330366747528011776", "text"=>"RT @Kalieezchild: Meditation has been killing it lately: http://t.co/Z6CPbgiQTQ (via @embodiedsacred)", "created_at"=>"2013-05-03T17:02:25Z", "user"=>"mermit_", "user_name"=>"Asaf Cohen", "user_profile_image"=>"http://a0.twimg.com/profile_images/349507150/beholder-mini_normal.jpg"}
• {"id"=>"330372622607073280", "text"=>"RT @Kalieezchild: Meditation has been killing it lately: http://t.co/Z6CPbgiQTQ (via @embodiedsacred)", "created_at"=>"2013-05-03T17:25:45Z", "user"=>"mux2000", "user_name"=>"mux 2000", "user_profile_image"=>"http://a0.twimg.com/profile_images/3201073144/db011314c15faae6d28d9925936c4a54_normal.jpeg"}
• {"id"=>"330398022020259841", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/sKRQgr8tZz", "created_at"=>"2013-05-03T19:06:41Z", "user"=>"erikayigzaw", "user_name"=>"Erika Yigzaw", "user_profile_image"=>"http://a0.twimg.com/profile_images/2940387822/1897576231f0f3170e1c38241540e72c_normal.jpeg"}
• {"id"=>"330417110415192064", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism,... http://t.co/i2AIbwUFt8", "created_at"=>"2013-05-03T20:22:32Z", "user"=>"jdusekphd", "user_name"=>"Jeffery Dusek PhD", "user_profile_image"=>"http://a0.twimg.com/sticky/default_profile_images/default_profile_6_normal.png"}
• {"id"=>"330417326300221440", "text"=>"@6B #PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion. http://t.co/i2AIbwUFt8", "created_at"=>"2013-05-03T20:23:24Z", "user"=>"jdusekphd", "user_name"=>"Jeffery Dusek PhD", "user_profile_image"=>"http://a0.twimg.com/sticky/default_profile_images/default_profile_6_normal.png"}
• {"id"=>"330481133487808512", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion http://t.co/LAU9jsSdqi", "created_at"=>"2013-05-04T00:36:56Z", "user"=>"DiogoProvete", "user_name"=>"Diogo B. Provete", "user_profile_image"=>"http://a0.twimg.com/profile_images/1161358665/d11b7594-d6cc-47a1-a168-149eb238ca02_normal.png"}
• {"id"=>"330485145226342401", "text"=>"@PLOSONE thanks for posting the yoga research! http://t.co/kBq5YzxOQe", "created_at"=>"2013-05-04T00:52:53Z", "user"=>"chrisfontes", "user_name"=>"Christopher Fontes", "user_profile_image"=>"http://a0.twimg.com/profile_images/1905813904/12c0816y_normal"}
• {"id"=>"330560210588557312", "text"=>"Daily yoga/mediation/prayer can change gene expression for the better decreasing inflammation & increasing metabolism http://t.co/32h56nhvEr", "created_at"=>"2013-05-04T05:51:10Z", "user"=>"AfterHoursProj", "user_name"=>"AfterHoursProject", "user_profile_image"=>"http://a0.twimg.com/profile_images/3551763220/5c8272fe86455f709f61ffb9e3820b87_normal.png"}
• {"id"=>"330598416801472512", "text"=>"Molecular mechanisms of relaxation seem to go through your mitochondrias http://t.co/GZ1xeJO7Ed", "created_at"=>"2013-05-04T08:22:59Z", "user"=>"_alitxu_", "user_name"=>"Alicia Amadoz", "user_profile_image"=>"http://a0.twimg.com/profile_images/1256817040/minitwitter_normal.jpg"}
• {"id"=>"330598809606426624", "text"=>"Molecular mechanisms of relaxation seem to go through the mitochondrias http://t.co/GZ1xeJO7Ed", "created_at"=>"2013-05-04T08:24:33Z", "user"=>"_alitxu_", "user_name"=>"Alicia Amadoz", "user_profile_image"=>"http://a0.twimg.com/profile_images/1256817040/minitwitter_normal.jpg"}
• {"id"=>"330621495179108352", "text"=>"New in-debth research. Meditation, Qigong, Vipassana & Tai chi improve metabolism, insulin secretion & inflammation. http://t.co/dSZr2v0jy5", "created_at"=>"2013-05-04T09:54:41Z", "user"=>"Bloom_in_Nature", "user_name"=>"Bloom-in-Nature", "user_profile_image"=>"http://a0.twimg.com/profile_images/3503857026/adb147953a6a6f87899479a4f46e900c_normal.jpeg"}
• {"id"=>"330642011898122240", "text"=>"New in-debth research. Meditation, Qigong, Vipassana & Tai chi improve metabolism, insulin secretion & inflammation. http://t.co/dSZr2v0jy5", "created_at"=>"2013-05-04T11:16:13Z", "user"=>"Bloom_in_Nature", "user_name"=>"Bloom-in-Nature", "user_profile_image"=>"http://a0.twimg.com/profile_images/3503857026/adb147953a6a6f87899479a4f46e900c_normal.jpeg"}
• {"id"=>"330661762871459842", "text"=>"New in-debth research. Meditation, Qigong, Vipassana & Tai chi improve metabolism, insulin secretion & inflammation. http://t.co/dSZr2v0jy5", "created_at"=>"2013-05-04T12:34:42Z", "user"=>"Bloom_in_Nature", "user_name"=>"Bloom-in-Nature", "user_profile_image"=>"http://a0.twimg.com/profile_images/3503857026/adb147953a6a6f87899479a4f46e900c_normal.jpeg"}
• {"id"=>"330664585117970432", "text"=>"New in-debth research. Meditation, Qigong, Vipassana & Tai chi improve metabolism, insulin secretion & inflammation. http://t.co/dSZr2v0jy5", "created_at"=>"2013-05-04T12:45:55Z", "user"=>"Bloom_in_Nature", "user_name"=>"Bloom-in-Nature", "user_profile_image"=>"http://a0.twimg.com/profile_images/3503857026/adb147953a6a6f87899479a4f46e900c_normal.jpeg"}
• {"id"=>"330965280194973697", "text"=>"New in-debth research. Meditation, Qigong, Vipassana & Tai chi improve metabolism, insulin secretion & inflammation. http://t.co/dSZr2v0jy5", "created_at"=>"2013-05-05T08:40:46Z", "user"=>"Bloom_in_Nature", "user_name"=>"Bloom-in-Nature", "user_profile_image"=>"http://a0.twimg.com/profile_images/3503857026/adb147953a6a6f87899479a4f46e900c_normal.jpeg"}
• {"id"=>"330988162027491332", "text"=>"Via @commonhealth Say Om: Researchers Find Gene Action Altered After Relaxation Practice http://t.co/ZdP2SR7thz & http://t.co/imgeN0Ktan", "created_at"=>"2013-05-05T10:11:41Z", "user"=>"pash22", "user_name"=>"Ash Paul", "user_profile_image"=>"http://a0.twimg.com/profile_images/3295856896/66ab958422d28c521d0143bddbb90233_normal.jpeg"}
• {"id"=>"331239531548401664", "text"=>"This is very interesting. This small study published in PLOS One shows that meditation, repeated prayers, tai chi,... http://t.co/HkVvswTlmn", "created_at"=>"2013-05-06T02:50:33Z", "user"=>"ZeNeece", "user_name"=>"Neece", "user_profile_image"=>"http://a0.twimg.com/profile_images/1193218944/ZeNeeceA_normal.jpg"}
• {"id"=>"331332224001650689", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflamation... http://t.co/MlLavvs5f0", "created_at"=>"2013-05-06T08:58:52Z", "user"=>"nabeel_in", "user_name"=>"nabeel basheer", "user_profile_image"=>"http://a0.twimg.com/profile_images/3327657588/80aec75ea777459d831eb67743e18ebd_normal.jpeg"}
• {"id"=>"331543925242331136", "text"=>"Need a vacation? Effects of relaxation on gene expression changes http://t.co/0rZLuFjipc", "created_at"=>"2013-05-06T23:00:06Z", "user"=>"genetics_blog", "user_name"=>"Stephen Turner", "user_profile_image"=>"http://a0.twimg.com/profile_images/1356990961/pic2-square-cropped-350x350_normal.jpg"}
• {"id"=>"331544331066408962", "text"=>"RT @genetics_blog: Need a vacation? Effects of relaxation on gene expression changes http://t.co/0rZLuFjipc", "created_at"=>"2013-05-06T23:01:42Z", "user"=>"HdzZ_Liliana", "user_name"=>"Liliana Andrés", "user_profile_image"=>"http://a0.twimg.com/profile_images/3474610815/f940b29bf93b9719ce396f4e8d9f850e_normal.png"}
• {"id"=>"331545451654430722", "text"=>"RT @genetics_blog: Need a vacation? Effects of relaxation on gene expression changes http://t.co/0rZLuFjipc", "created_at"=>"2013-05-06T23:06:10Z", "user"=>"VujkovicM", "user_name"=>"Marijana Vujkovic", "user_profile_image"=>"http://a0.twimg.com/profile_images/3212974946/f6bee1639f1ce9771ad1762bf3ed44b9_normal.jpeg"}
• {"id"=>"331586386090135552", "text"=>"RT @genetics_blog: Need a vacation? Effects of relaxation on gene expression changes http://t.co/0rZLuFjipc", "created_at"=>"2013-05-07T01:48:49Z", "user"=>"xiaojuma", "user_name"=>"Xiaoju Ma", "user_profile_image"=>"http://a0.twimg.com/profile_images/3593553405/17ef8b48a46ab135dd7cc142977ce7d2_normal.jpeg"}
• {"id"=>"331632510461161472", "text"=>"http://t.co/RuVpYGvVZF. LA MEDITAZIONE ALLUNGA LA VITA http://t.co/tgxYBvbJZC", "created_at"=>"2013-05-07T04:52:06Z", "user"=>"ANDROUROLOGO", "user_name"=>"Mario De Siati", "user_profile_image"=>"http://a0.twimg.com/profile_images/1240268173/PC150003_normal.JPG"}
• {"id"=>"331687606779772929", "text"=>"Scientific proof for >2500yr old practices - those who do it, knew it all along - relaxation & molecular changes.http://t.co/Arpx14iAqL", "created_at"=>"2013-05-07T08:31:02Z", "user"=>"medeadelaid", "user_name"=>"Adelaide Ungerer", "user_profile_image"=>"http://a0.twimg.com/profile_images/1509913610/794px-William-Adolphe_Bouguereau__1825-1905__-_The_Wave__1896__normal.jpg"}
• {"id"=>"331708532187607040", "text"=>"Mindfulness and yoga can actually can change the 'genetic-expression'.\nhttp://t.co/7AqJx1srVt", "created_at"=>"2013-05-07T09:54:11Z", "user"=>"Sandra9Tideman", "user_name"=>"Human Givens NL", "user_profile_image"=>"http://a0.twimg.com/profile_images/3409931585/02f130b06a5d773a69af3ca64f90f571_normal.jpeg"}
• {"id"=>"331752260377907200", "text"=>"http://t.co/6z7xnLZCNl http://t.co/tyWDb0hNsD", "created_at"=>"2013-05-07T12:47:57Z", "user"=>"TangoFF", "user_name"=>"flavia fanin", "user_profile_image"=>"http://a0.twimg.com/sticky/default_profile_images/default_profile_6_normal.png"}
• {"id"=>"331817793651617795", "text"=>"Harde bewijzen voor Mind-Body samenhang: verminderde ontstekings activiteit door meditatie en ontspanning\n\nhttp://t.co/tfic4lUvNg", "created_at"=>"2013-05-07T17:08:21Z", "user"=>"AndreasCardio", "user_name"=>"Andreas Lucassen", "user_profile_image"=>"http://a0.twimg.com/profile_images/3054972885/8fa66d327b01c28d4b716f92d649b1fc_normal.jpeg"}
• {"id"=>"331871080652349440", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/sh6WxU1k6O", "created_at"=>"2013-05-07T20:40:06Z", "user"=>"ibridazioni", "user_name"=>"Gianandrea Giacoma", "user_profile_image"=>"http://a0.twimg.com/profile_images/1137913653/by_cat_frog_design_maggio_2010_normal.JPG"}
• {"id"=>"332068694530338816", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/2IQYAe3xyo", "created_at"=>"2013-05-08T09:45:20Z", "user"=>"SergioPrimerano", "user_name"=>"Sergio Primerano", "user_profile_image"=>"http://a0.twimg.com/profile_images/2932564620/db2041a2fb9f8d1e553c5b53c1250fac_normal.jpeg"}
• {"id"=>"332937741308424192", "text"=>"Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:18:37Z", "user"=>"markhymanmd", "user_name"=>"Mark Hyman, M.D.", "user_profile_image"=>"http://a0.twimg.com/profile_images/3297753007/985742bed59d2f1cb9784c21ba05c1bf_normal.jpeg"}
• {"id"=>"332937845872398336", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:19:02Z", "user"=>"Sherstar", "user_name"=>"Sherry Baker", "user_profile_image"=>"http://a0.twimg.com/profile_images/1624159438/1_normal.jpg"}
• {"id"=>"332938561915604992", "text"=>"Yoga! RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/CHLLAFb3PM", "created_at"=>"2013-05-10T19:21:53Z", "user"=>"RunningCarrotVT", "user_name"=>"Lauren F.", "user_profile_image"=>"http://a0.twimg.com/profile_images/3593301947/1e647bd7d146ddcd4b73acfa41a79c06_normal.jpeg"}
• {"id"=>"332938770443796480", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:22:43Z", "user"=>"MaureenGApeach", "user_name"=>"Maureen", "user_profile_image"=>"http://a0.twimg.com/profile_images/2479865960/image_normal.jpg"}
• {"id"=>"332938867793600512", "text"=>"Relaxation response decreases inflammation http://t.co/ti94xJCGQD", "created_at"=>"2013-05-10T19:23:06Z", "user"=>"NashBeth", "user_name"=>"Beth Nash", "user_profile_image"=>"http://a0.twimg.com/profile_images/3056038361/ab5ba61f70a3ad544b376783b04e784e_normal.jpeg"}
• {"id"=>"332939079199109122", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:23:56Z", "user"=>"laurenakrause", "user_name"=>"Lauren", "user_profile_image"=>"http://a0.twimg.com/profile_images/2763934901/0a589539478dda6222416ec61385856f_normal.jpeg"}
• {"id"=>"332939623217115138", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:26:06Z", "user"=>"mostrolenk", "user_name"=>"Michael Ostrolenk", "user_profile_image"=>"http://a0.twimg.com/profile_images/2814454140/a0b8f577e18a4332a7721eb182f032d1_normal.jpeg"}
• {"id"=>"332940608261996544", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:30:01Z", "user"=>"NaturalJ", "user_name"=>"Julie Wilson", "user_profile_image"=>"http://a0.twimg.com/profile_images/1172516711/Julie_head_shot_normal.jpg"}
• {"id"=>"332942499918258176", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:37:32Z", "user"=>"DrCharisse", "user_name"=>"Charisse Gibert", "user_profile_image"=>"http://a0.twimg.com/profile_images/2781288804/40d978d2db219524c5d00aafc0feb622_normal.jpeg"}
• {"id"=>"332943758461112322", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:42:32Z", "user"=>"Reversedmagazin", "user_name"=>"Reversed mag", "user_profile_image"=>"http://a0.twimg.com/profile_images/3033684546/7c37db775cb7b2654ce37e89d021ae27_normal.jpeg"}
• {"id"=>"332944041056550912", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:43:39Z", "user"=>"Amazing_Cafe", "user_name"=>"Amazing Cafe", "user_profile_image"=>"http://a0.twimg.com/profile_images/3453709255/ad01aa1dd6fd06f7175fef1e96c09af3_normal.jpeg"}
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• {"id"=>"332946824572829697", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T19:54:43Z", "user"=>"LiveBlissNow", "user_name"=>"Lynne Goldberg", "user_profile_image"=>"http://a0.twimg.com/profile_images/3504405103/b2726fc4b05c0f26a4da696fa6a31b12_normal.jpeg"}
• {"id"=>"332947635231133696", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/HbLVK2rwcn", "created_at"=>"2013-05-10T19:57:56Z", "user"=>"NutritionSchool", "user_name"=>"IntegrativeNutrition", "user_profile_image"=>"http://a0.twimg.com/profile_images/1368569146/INN-Avatar_normal.jpg"}
• {"id"=>"332948557957054464", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T20:01:36Z", "user"=>"tri_kines", "user_name"=>"Clayton Nielsen", "user_profile_image"=>"http://a0.twimg.com/profile_images/2239221508/profile_pic_normal.jpg"}
• {"id"=>"332951288021123074", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T20:12:27Z", "user"=>"KeVitaDrinks", "user_name"=>"KeVita ", "user_profile_image"=>"http://a0.twimg.com/profile_images/3380218037/19f1902f694abc7fbf5081ad581d9f7d_normal.png"}
• {"id"=>"332954380221415424", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T20:24:44Z", "user"=>"NicholaGeraghty", "user_name"=>"Nichola Geraghty", "user_profile_image"=>"http://a0.twimg.com/profile_images/2714470962/d9332021bf9a41dec911070546a4b8f1_normal.jpeg"}
• {"id"=>"332977019342159873", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T21:54:42Z", "user"=>"Sonya_Barnes_", "user_name"=>"Sonya Barnes", "user_profile_image"=>"http://a0.twimg.com/profile_images/2747441251/41322ba8521063bc1fd0aa9d03f73479_normal.jpeg"}
• {"id"=>"332977617831600128", "text"=>"Science in @plosone RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function & reduces inflammation. http://t.co/W1olyGnZro", "created_at"=>"2013-05-10T21:57:05Z", "user"=>"teiwaz", "user_name"=>"Camron Assadi", "user_profile_image"=>"http://a0.twimg.com/profile_images/1766821140/481_normal.jpg"}
• {"id"=>"332990381509709825", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T22:47:48Z", "user"=>"angelwhitmire", "user_name"=>"awhitmire", "user_profile_image"=>"http://a0.twimg.com/profile_images/2298604403/image_normal.jpg"}
• {"id"=>"332994088162959361", "text"=>"#Foryourhealth “@markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces inflammation. http://t.co/b6n7R1sZVb”", "created_at"=>"2013-05-10T23:02:32Z", "user"=>"NewViewWellness", "user_name"=>"New View Wellness", "user_profile_image"=>"http://a0.twimg.com/profile_images/3566952127/608ec7a30416f00e9edfbb539e8ff54b_normal.jpeg"}
• {"id"=>"333002010364346368", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-10T23:34:00Z", "user"=>"SjogrensForum", "user_name"=>"Sjögrens Forum", "user_profile_image"=>"http://a0.twimg.com/profile_images/1083947731/birds_normal.jpg"}
• {"id"=>"333028509058473984", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-11T01:19:18Z", "user"=>"Lany0079", "user_name"=>"Lany", "user_profile_image"=>"http://a0.twimg.com/profile_images/3514610046/9fba6ad63832142309e43f1e5caae4ec_normal.jpeg"}
• {"id"=>"333108364580098048", "text"=>"“@markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/uV0RmBkGnD”", "created_at"=>"2013-05-11T06:36:37Z", "user"=>"EatYrselfHappy", "user_name"=>"Nichola Geraghty", "user_profile_image"=>"http://a0.twimg.com/profile_images/3393240152/4534001b6407ebc1303ae21c2ecd0ef5_normal.jpeg"}
• {"id"=>"333295799196856321", "text"=>"Relaxation techniques and the impact on genetic responses - more evidence on the psychoneurobiological system. http://t.co/9glYEncUlz", "created_at"=>"2013-05-11T19:01:25Z", "user"=>"ScottDUK", "user_name"=>"Scott Drawer", "user_profile_image"=>"http://a0.twimg.com/profile_images/3180181565/22c9669cfaa90dfa0e6c9e7a98206f4d_normal.jpeg"}
• {"id"=>"333334886674993152", "text"=>"\"@ScottDUK: Relaxation techniques- more evidence on the psychoneurobiological system. http://t.co/mjzFP98EOh\" nice paper", "created_at"=>"2013-05-11T21:36:44Z", "user"=>"dkhammy", "user_name"=>"Dave Hamilton", "user_profile_image"=>"http://a0.twimg.com/profile_images/1376209500/david_hamilton_normal.JPG"}
• {"id"=>"333356132968050688", "text"=>"RT @dkhammy: \"@ScottDUK: Relaxation techniques- more evidence on the psychoneurobiological system. http://t.co/mjzFP98EOh\" nice paper", "created_at"=>"2013-05-11T23:01:10Z", "user"=>"PoulosNick", "user_name"=>"Nick Poulos", "user_profile_image"=>"http://a0.twimg.com/profile_images/1987503753/Nick_normal.png"}
• {"id"=>"333362669157486593", "text"=>"RT @dkhammy: \"@ScottDUK: Relaxation techniques- more evidence on the psychoneurobiological system. http://t.co/mjzFP98EOh\" nice paper", "created_at"=>"2013-05-11T23:27:08Z", "user"=>"AlxPett", "user_name"=>"Alex Pett", "user_profile_image"=>"http://a0.twimg.com/profile_images/3544236948/1fdfa224314cd6535bf542844d537e84_normal.jpeg"}
• {"id"=>"333401577371082752", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-12T02:01:45Z", "user"=>"KempErika", "user_name"=>"Erika", "user_profile_image"=>"http://a0.twimg.com/profile_images/2358258501/image_normal.jpg"}
• {"id"=>"333469712799371264", "text"=>"Relaxation Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion, and Inflammatory Pathways http://t.co/LMNjbwsXjm", "created_at"=>"2013-05-12T06:32:29Z", "user"=>"ashw1n", "user_name"=>"Ashwin Kumar", "user_profile_image"=>"http://a0.twimg.com/profile_images/2447569923/c258zx6v8g1iq5z3nm1z_normal.jpeg"}
• {"id"=>"333622836864372736", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/jSSqgFVKfM", "created_at"=>"2013-05-12T16:40:57Z", "user"=>"MattChallacombe", "user_name"=>"Matt Challacombe", "user_profile_image"=>"http://a0.twimg.com/profile_images/1458886938/shikamaru_normal.png"}
• {"id"=>"333724186977652736", "text"=>"MINDFULNESS & THE RELAXATION RESPONSE\nhttp://t.co/pLsA4VDZnI http://t.co/3libEBPmGT", "created_at"=>"2013-05-12T23:23:41Z", "user"=>"EatBreatheThink", "user_name"=>"Tina Chadda MD", "user_profile_image"=>"http://a0.twimg.com/profile_images/3225903637/02c07d44985d9deec162252e758b97cc_normal.jpeg"}
• {"id"=>"333807725018492929", "text"=>"RT @markhymanmd: Yoga boosts energy metabolism, improves insulin function and reduces & inflammation. http://t.co/kJHw9qwToC", "created_at"=>"2013-05-13T04:55:38Z", "user"=>"olybyhand", "user_name"=>"Wendy Daray", "user_profile_image"=>"http://a0.twimg.com/profile_images/2915699248/4a05684c66bc9540a34d4f1205827cb3_normal.jpeg"}
• {"id"=>"333915302385569793", "text"=>"Very interesting article!\nhttp://t.co/ouP4YVpz9w http://t.co/n4FvZUkMYt", "created_at"=>"2013-05-13T12:03:06Z", "user"=>"NirvanaWellness", "user_name"=>"Nirvana Wellness", "user_profile_image"=>"http://a0.twimg.com/profile_images/2540080120/ekpckaw01vfko441z8i0_normal.jpeg"}
• {"id"=>"335648053493104640", "text"=>"Razones cientificas para ser Budista Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabo..... http://t.co/bvyhHOkknC", "created_at"=>"2013-05-18T06:48:26Z", "user"=>"snrepele", "user_name"=>"Santiago Peñarreta", "user_profile_image"=>"http://a0.twimg.com/profile_images/3565100153/6d71961e0d006b5eb3c5cabc2fcf0ad1_normal.jpeg"}
• {"id"=>"335697416437264384", "text"=>"Nu är det bevisat - IGEN :-)\nhttp://t.co/kO5PtThwy2 http://t.co/qSp3mPdixp", "created_at"=>"2013-05-18T10:04:35Z", "user"=>"atmajyoti", "user_name"=>"Atmajyoti Yoga", "user_profile_image"=>"http://a0.twimg.com/profile_images/3574107370/30e144ef8a149584cc834cf75e57defe_normal.jpeg"}
• {"id"=>"336997456468377601", "text"=>"Relaxation Response improves gene activity for mitochondrial function, metabolism, inflammation http://t.co/ERM6nbDi1K @PLOSONE", "created_at"=>"2013-05-22T00:10:29Z", "user"=>"Vita_IQ", "user_name"=>"Vita IQ", "user_profile_image"=>"http://a0.twimg.com/profile_images/3482496897/4461dd6d8358f57575bdbbb968693848_normal.png"}
• {"id"=>"337313450055311360", "text"=>"@healthyhalifax here you go http://t.co/62mgdaDoTE", "created_at"=>"2013-05-22T21:06:08Z", "user"=>"LisaJohnson", "user_name"=>"Lisa Johnson", "user_profile_image"=>"http://a0.twimg.com/profile_images/2837231951/73b3e967e0bc5179e84fa072e1dc8ed3_normal.png"}
• {"id"=>"337593091877900288", "text"=>"No way!\nRelaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion...#PLOSONE\nhttp://t.co/qfBi4PWvnQ", "created_at"=>"2013-05-23T15:37:19Z", "user"=>"marcohbello", "user_name"=>"Marco Bello", "user_profile_image"=>"http://a0.twimg.com/profile_images/3620052880/5f50dee493f975bade3aaea92e54dea4_normal.jpeg"}
• {"id"=>"337759753096818688", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes http://t.co/OZpnGxTAfl", "created_at"=>"2013-05-24T02:39:35Z", "user"=>"CefleNews", "user_name"=>"CEFLE", "user_profile_image"=>"http://a0.twimg.com/profile_images/1179544474/logo_Cefle_normal.JPG"}
• {"id"=>"337769612391358464", "text"=>"New Age nonsense? Paradigm shifting science? Meditation is claimed to be healthy. Insulin up! Blood sugar down! Ommmm http://t.co/2xLe8LMNad", "created_at"=>"2013-05-24T03:18:45Z", "user"=>"DanGraur", "user_name"=>"Dan Graur", "user_profile_image"=>"http://a0.twimg.com/profile_images/3287733667/3d2310d0277dc1e07aa1bbea16c417f8_normal.jpeg"}
• {"id"=>"338706256711790593", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion... http://t.co/7dtIVBYREy", "created_at"=>"2013-05-26T17:20:39Z", "user"=>"NamasteATL", "user_name"=>"Eleanor Fleming", "user_profile_image"=>"http://a0.twimg.com/profile_images/2376846970/image_normal.jpg"}
• {"id"=>"338766121316524032", "text"=>"PLOS ONE: Relaxation Response Induces Temporal Transcriptome Changes... #psychology http://t.co/AMFIncp2Jv", "created_at"=>"2013-05-26T21:18:31Z", "user"=>"uhmammamia", "user_name"=>"il barone Arian®", "user_profile_image"=>"http://a0.twimg.com/profile_images/3702133514/506c29500a58a14ab22a8730183f787f_normal.jpeg"}
• {"id"=>"339580797063413763", "text"=>"PLOS ONE: Relaxation Response Induces Temporal Transcriptome Changes in... http://t.co/xQLNxvp4Ld", "created_at"=>"2013-05-29T03:15:45Z", "user"=>"latirina", "user_name"=>"Medical", "user_profile_image"=>"http://a0.twimg.com/profile_images/2832838701/151524e9cb9dc28c898e5923cce76763_normal.png"}
• {"id"=>"341278387505082368", "text"=>"Relaxation response is associated with rapid genomic changes related to stress pathways. http://t.co/FgG0RN9IEV", "created_at"=>"2013-06-02T19:41:22Z", "user"=>"WhereAmINow", "user_name"=>"Colin Ellard", "user_profile_image"=>"http://a0.twimg.com/profile_images/2260560183/ellard_shead_normal.jpg"}
• {"id"=>"341840479681380352", "text"=>"Relaxation response changed gene expression resulting in psychiatric resilience: http://t.co/c9LFpGcN5n Maybe it's biological?", "created_at"=>"2013-06-04T08:54:56Z", "user"=>"in_psych", "user_name"=>"Joe Hayes", "user_profile_image"=>"http://a0.twimg.com/profile_images/1671176713/joe_normal.jpg"}
• {"id"=>"341950426456932352", "text"=>"العلاج بالتأمل يؤثر على الجينات!\nدراسة: \nتمارين التأمل تساهم في:\nتنشيط جينات التكيف الخلوي،\nوتثبيط جينات بعض الأمراض. http://t.co/2rVGfHS3iU", "created_at"=>"2013-06-04T16:11:49Z", "user"=>"faalosaimi", "user_name"=>"فهد بن دخيل العصيمي", "user_profile_image"=>"http://a0.twimg.com/profile_images/2111067207/image_normal.jpg"}
• {"id"=>"342088004128620544", "text"=>"http://t.co/EvNvBk6zST http://t.co/uJOOJuj7mT", "created_at"=>"2013-06-05T01:18:30Z", "user"=>"somnogen", "user_name"=>"Somnogen", "user_profile_image"=>"http://a0.twimg.com/profile_images/1691148715/somnogen-facebook_normal.jpg"}
• {"id"=>"342634228665679872", "text"=>"http://t.co/ZfOGVOjaXk\n\nMore research on the mechanisms... http://t.co/iNSeAXGV43", "created_at"=>"2013-06-06T13:29:00Z", "user"=>"WahlsFoundation", "user_name"=>"TheWahlsFoundation", "user_profile_image"=>"http://a0.twimg.com/profile_images/1276000026/TWF-logo-terry_normal.jpg"}
• {"id"=>"342636249603002368", "text"=>"“@WahlsFoundation: http://t.co/qwcE9Xyxuc\nMore research on the mechanisms... http://t.co/XRuCa85aPo” @acigartsen", "created_at"=>"2013-06-06T13:37:02Z", "user"=>"KimVanWetten", "user_name"=>"Kim van Wetten", "user_profile_image"=>"http://a0.twimg.com/profile_images/1451862617/Twitter_photo3_normal.jpg"}
• {"id"=>"342636302883225600", "text"=>"RT @WahlsFoundation: http://t.co/ZfOGVOjaXk\n\nMore research on the mechanisms... http://t.co/iNSeAXGV43", "created_at"=>"2013-06-06T13:37:15Z", "user"=>"KimVanWetten", "user_name"=>"Kim van Wetten", "user_profile_image"=>"http://a0.twimg.com/profile_images/1451862617/Twitter_photo3_normal.jpg"}
• {"id"=>"343385287545737216", "text"=>"A little more science that suggest breathing deeply is a good, good thing! #ashtanga #yoga #breath http://t.co/QLFFxuHk3V", "created_at"=>"2013-06-08T15:13:26Z", "user"=>"Bioyogi", "user_name"=>"Rebecca Powell", "user_profile_image"=>"http://a0.twimg.com/profile_images/1231073256/yoga_headshot_normal.JPG"}
• {"id"=>"343945725283008513", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabo.., Insulin Secretion, Inflam... http://t.co/T3IhxgYwLk", "created_at"=>"2013-06-10T04:20:25Z", "user"=>"BingElaine", "user_name"=>"Elaine Bing", "user_profile_image"=>"http://a0.twimg.com/profile_images/1581965876/jse_DSC03263_normal.jpg"}
• {"id"=>"344320530381430784", "text"=>"Scientific essay on meditation, yoga and gene expression.\n\nhttp://t.co/jXqGxQj6MM", "created_at"=>"2013-06-11T05:09:46Z", "user"=>"yogabuddhism", "user_name"=>"the other shore", "user_profile_image"=>"http://a0.twimg.com/profile_images/3445866714/e39ac466124d0f359a60af978a1acdec_normal.jpeg"}
• {"id"=>"347069138700750849", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism... http://t.co/ekxL2RETKy", "created_at"=>"2013-06-18T19:11:45Z", "user"=>"VVyazovskiy", "user_name"=>"Vlad Vyazovskiy", "user_profile_image"=>"http://a0.twimg.com/profile_images/2645932495/7abb2307bc0babc78d5689facfac0bbf_normal.png"}
• {"id"=>"347710561229893632", "text"=>"#meditation #prayer #yoga Relaxation Response Induces Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/wyx0yPeWIO", "created_at"=>"2013-06-20T13:40:32Z", "user"=>"dana_frost", "user_name"=>"Dana Frost", "user_profile_image"=>"http://a0.twimg.com/profile_images/198455174/IMG_0127_normal.jpg"}
• {"id"=>"348149505750863872", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/3bSLpdoqU8", "created_at"=>"2013-06-21T18:44:45Z", "user"=>"thejcchase", "user_name"=>"Joseph (Joe) Chase", "user_profile_image"=>"http://a0.twimg.com/profile_images/3263161534/0ee64315d9f551811db71bce6e48eb43_normal.jpeg"}
• {"id"=>"349374996151406592", "text"=>"Физиологи (Бостон) обосновали влияние медитации (молитвы) на метаболизм организма.Отличный воспроизводимый результат http://t.co/NJ2uTEXYVF", "created_at"=>"2013-06-25T03:54:24Z", "user"=>"Vozmitel", "user_name"=>"Iryna Vozmitel", "user_profile_image"=>"http://a0.twimg.com/profile_images/950498729/Irins_i_normal.jpg"}
• {"id"=>"349376242790825984", "text"=>"Вольный перевод о влиянии медитации http://t.co/NJ2uTEXYVF (типа \"мнение редакции не совпадает\") здесь:http://t.co/MfNCh6NJOp", "created_at"=>"2013-06-25T03:59:22Z", "user"=>"Vozmitel", "user_name"=>"Iryna Vozmitel", "user_profile_image"=>"http://a0.twimg.com/profile_images/950498729/Irins_i_normal.jpg"}
• {"id"=>"353464777290428417", "text"=>"Relaxing really is good for you, ok?! http://t.co/irQPaDk0mK", "created_at"=>"2013-07-06T10:45:44Z", "user"=>"chrisdymond", "user_name"=>"Chris Dymond", "user_profile_image"=>"http://a0.twimg.com/profile_images/3698983669/707e95d0951ab7a704d434e674d3761a_normal.jpeg"}
• {"id"=>"353465174184837120", "text"=>"RT @chrisdymond: Relaxing really is good for you, ok?! http://t.co/irQPaDk0mK", "created_at"=>"2013-07-06T10:47:19Z", "user"=>"basculeteller", "user_name"=>"John Marshall", "user_profile_image"=>"http://a0.twimg.com/profile_images/3122280225/767b684e4e084b3cd6df83b0847173ad_normal.jpeg"}
• {"id"=>"355469019270225920", "text"=>"http://t.co/2QQ1RedSmj", "created_at"=>"2013-07-11T23:29:53Z", "user"=>"AcumedicineBH", "user_name"=>"Mitra Daneshrad DAOM", "user_profile_image"=>"http://a0.twimg.com/profile_images/1738859746/mimi3_small4_normal.png"}
• {"id"=>"355542785769746433", "text"=>"PLOS ONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism,... http://t.co/XnQEYgEyNs", "created_at"=>"2013-07-12T04:23:00Z", "user"=>"durastudio", "user_name"=>"dura studio", "user_profile_image"=>"http://a0.twimg.com/profile_images/649544217/chair2_normal.jpg"}
• {"id"=>"355542854338220032", "text"=>"PLOS ONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism,... http://t.co/rusZe0DdlD", "created_at"=>"2013-07-12T04:23:16Z", "user"=>"braingurus", "user_name"=>"Kelley Graham", "user_profile_image"=>"http://a0.twimg.com/profile_images/143043081/light_bulb.twitter_200px_sq_normal.png"}
• {"id"=>"355545301488111616", "text"=>"Some interesting research about the relaxation response (available through meditation, e.g.). PLOS ONE\nhttp://t.co/thfFudagnu", "created_at"=>"2013-07-12T04:33:00Z", "user"=>"GodDoesnt", "user_name"=>"James Lindsay", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000115706140/25145a019c3fa97afc6c5d1831e3c360_normal.jpeg"}
• {"id"=>"355545625879781377", "text"=>"RT @GodDoesnt: Some interesting research about the relaxation response (available through meditation, e.g.). PLOS ONE\nhttp://t.co/thfFudagnu", "created_at"=>"2013-07-12T04:34:17Z", "user"=>"sexyprimate", "user_name"=>"Nischal", "user_profile_image"=>"http://a0.twimg.com/profile_images/3636963941/16a39146397ecb6421b2d2b4ad622d76_normal.jpeg"}
• {"id"=>"359120817126252544", "text"=>"upgrading DNA through meditation/yoga/deep breathing http://t.co/9dgMWbOR8S", "created_at"=>"2013-07-22T01:20:49Z", "user"=>"inneRoots", "user_name"=>"s31fBee'N", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000073361473/e747406c8e38ef9d52329185f7f62d24_normal.jpeg"}
• {"id"=>"359363477304905728", "text"=>"Research on meditation and modification in gene expression. Article: http://t.co/UM3CwJ3hP5 Academic Paper: http://t.co/hICg4iUww1", "created_at"=>"2013-07-22T17:25:04Z", "user"=>"sandhyopasaka", "user_name"=>"sandhyopasaka", "user_profile_image"=>"http://a0.twimg.com/profile_images/1443946606/guru_shishya_rajendra_kedige_normal.jpg"}
• {"id"=>"362571069560864768", "text"=>"http://t.co/K2rO6RXFfn", "created_at"=>"2013-07-31T13:50:53Z", "user"=>"Richurlex", "user_name"=>"HUAMAN Richard", "user_profile_image"=>"http://a0.twimg.com/profile_images/1386907580/13952_209058610853_825625853_3081562_8045599_n_normal.jpg"}
• {"id"=>"366962585750347776", "text"=>"#PLOSONE: Relaxation Response Induces Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/iCcETLD8yp", "created_at"=>"2013-08-12T16:41:12Z", "user"=>"phase2mind", "user_name"=>"David Korsunsky", "user_profile_image"=>"http://a0.twimg.com/profile_images/1028409080/SF_normal.jpg"}
• {"id"=>"367646651915063297", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/3MaaQA06Wm", "created_at"=>"2013-08-14T13:59:27Z", "user"=>"mags397", "user_name"=>"Magali Chohan", "user_profile_image"=>"http://a0.twimg.com/profile_images/1813545819/195_12987326431_599621431_745001_9015_n_1__normal.jpg"}
• {"id"=>"370312519623008256", "text"=>"A worth read for everyone in our too-fast, stressed-based society. http://t.co/GBlzODBWHS The full report: http://t.co/XUlr89C8L2", "created_at"=>"2013-08-21T22:32:39Z", "user"=>"wolfnowl", "user_name"=>"Mike Nelson Pedde", "user_profile_image"=>"http://a0.twimg.com/profile_images/1154595119/DSCF13789_normal.jpg"}
• {"id"=>"373967936584577024", "text"=>"PLOS ONE: Relax Response Induces Temporal Transcriptome Changes in Energy Mets, Insulin Secret & Inflamm Pathways http://t.co/QVbK3QGG5I", "created_at"=>"2013-09-01T00:37:58Z", "user"=>"mem_lewis", "user_name"=>"Mary Lewis", "user_profile_image"=>"http://a0.twimg.com/profile_images/1820813758/Lighthouse_normal.jpg"}
• {"id"=>"375396217812832257", "text"=>"Alter DNA with the Relaxation Response. I've only read the abstract so far, but very interesting premise: http://t.co/8m7wWmbIxR", "created_at"=>"2013-09-04T23:13:27Z", "user"=>"NickEfthimiou", "user_name"=>"Nick Efthimiou", "user_profile_image"=>"http://a0.twimg.com/profile_images/1107669439/30520_10150193854785534_530955533_12669430_2579736_n_normal.jpg"}
• {"id"=>"403957335460036608", "text"=>"@mkhaliq1 @tonypanzera Metta and mindfullness meditation do - scientifically - contribute to better health. http://t.co/vpCO2FCCAB", "created_at"=>"2013-11-22T18:45:08Z", "user"=>"abdulalikon", "user_name"=>"AbdulAlikon", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1339849682/Feie_normal.jpg"}
• {"id"=>"411631657750237184", "text"=>"PLOS ONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism,... http://t.co/i6FWOJA9AI", "created_at"=>"2013-12-13T23:00:09Z", "user"=>"ClinicaCTA", "user_name"=>"Clinica CTA", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1862606664/logo_normal.jpg"}
• {"id"=>"430414806575611904", "text"=>"Always believed that we would see mental states can modify very basic biology. Still astonishing to see in print. http://t.co/EjwSxMfkq7", "created_at"=>"2014-02-03T18:57:41Z", "user"=>"drccushing", "user_name"=>"Christopher Cushing", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2856520033/d7d46265ae32a2d585e07ca33ad238d0_normal.png"}
• {"id"=>"436228480372461568", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflam... http://t.co/arfxuHdgT1", "created_at"=>"2014-02-19T19:59:09Z", "user"=>"ProfScoles", "user_name"=>"Sebastian Scoles", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3776741035/762f547400c7473db5638057068b68fa_normal.jpeg"}
• {"id"=>"439858415444459520", "text"=>"Relaxation response from yoga/meditation/deepbreathing can affect gene expression #Research http://t.co/oInAYN515I & http://t.co/XEza0nrib5", "created_at"=>"2014-03-01T20:23:13Z", "user"=>"_stress_less_", "user_name"=>"Stress Less For Life", "user_profile_image"=>"http://pbs.twimg.com/profile_images/434844795240841216/9AsTF5yK_normal.jpeg"}
• {"id"=>"440215911908130816", "text"=>"RT @_stress_less_: Relaxation response from yoga/meditation/deepbreathing can affect gene expression #Research http://t.co/oInAYN515I & htt…", "created_at"=>"2014-03-02T20:03:46Z", "user"=>"notcrazyteens", "user_name"=>"You're Not Crazy", "user_profile_image"=>"http://pbs.twimg.com/profile_images/429103804991012865/YDoaTFL2_normal.png"}
• {"id"=>"441786050189332480", "text"=>"RT @_stress_less_: Relaxation response from yoga/meditation/deepbreathing can affect gene expression #Research http://t.co/oInAYN515I & htt…", "created_at"=>"2014-03-07T04:02:57Z", "user"=>"hallnicks", "user_name"=>"Damius", "user_profile_image"=>"http://pbs.twimg.com/profile_images/440746536536793088/LRojQ-RU_normal.jpeg"}
• {"id"=>"443767784024342528", "text"=>"статья в PLoS One http://t.co/oqeOJGtHCX о том, что обучение т… http://t.co/X3wjUXkDAB", "created_at"=>"2014-03-12T15:17:39Z", "user"=>"gvardovich", "user_name"=>"gvard", "user_profile_image"=>"http://pbs.twimg.com/profile_images/744025363/av_G-logo_normal.jpg"}
• {"id"=>"447446665788542976", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism... http://t.co/kqj0sjsg6q", "created_at"=>"2014-03-22T18:56:12Z", "user"=>"BryanBarksdale", "user_name"=>"Bryan Barksdale", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1697006516/296902_10150942202825007_553260006_21270067_1727016638_n_normal.jpg"}
• {"id"=>"449177369262030848", "text"=>"RelaxationResponse Induces Temporal Transcriptome Changes in Energy Metabolism InsulinSecretion Inflammatory http://t.co/gdrDh8NvS6 #PLOSONE", "created_at"=>"2014-03-27T13:33:24Z", "user"=>"tmealha", "user_name"=>"Tânia Mealha", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3367423797/2a806080434a10776dccd369cf0ef2a4_normal.jpeg"}
• {"id"=>"458614863213125632", "text"=>"De effecten van #meditatie en #mindfulness bewezen? Wel spannende richtingen van onderzoek. http://t.co/xgc88Cohae", "created_at"=>"2014-04-22T14:34:38Z", "user"=>"bewustmoeder", "user_name"=>"mindful-mothers.com", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1869638688/LogoColorNoText_normal.jpeg"}
• {"id"=>"481700944938147842", "text"=>"[X-post from /r/nondirective by /u/alien_lanes] Relaxation response (meditation) evokes enhanced expression of... http://t.co/JG18YR9YSK", "created_at"=>"2014-06-25T07:30:29Z", "user"=>"BrainSpeakMag", "user_name"=>"BrainSpeak Magazine", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000371354533/268c783c0b4060c4f4a6a13a2cf808ae_normal.jpeg"}
• {"id"=>"499563239249039361", "text"=>"@STOP_Alzheimers we should all just do #Yoga and the problem is gone #PLOSONE: http://t.co/hVO2zbnFEP", "created_at"=>"2014-08-13T14:28:52Z", "user"=>"PimpYourScience", "user_name"=>"Pimp Your Science", "user_profile_image"=>"http://pbs.twimg.com/profile_images/491533297722212353/Yc8gd_-B_normal.jpeg"}
• {"id"=>"519319786694516737", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes Energy Metabolism, Insulin Secretion Inflammatory pathways http://t.co/k9J5Sk9dvK", "created_at"=>"2014-10-07T02:54:20Z", "user"=>"TonySearl", "user_name"=>"TonySearl", "user_profile_image"=>"http://pbs.twimg.com/profile_images/458897429899665408/yeQHHJOp_normal.jpeg"}
• {"id"=>"530552581589061633", "text"=>"#Meditation alters gene expression and #inflammation. Ommmmmm\nhttp://t.co/u6BdZssxAW", "created_at"=>"2014-11-07T02:49:27Z", "user"=>"HouseCallDaily", "user_name"=>"Dr. Daily", "user_profile_image"=>"http://pbs.twimg.com/profile_images/526534458715807744/_xOacWYI_normal.jpeg"}
• {"id"=>"537619003943178240", "text"=>"Day30 #TBIrewire \nMeditation alters gene expression and #inflammation. Try it for #TBI! \nhttp://t.co/m5tXvANaBs via @HouseCallDaily #66Days", "created_at"=>"2014-11-26T14:48:53Z", "user"=>"TBI_BrainWreck", "user_name"=>"TBIRewire", "user_profile_image"=>"http://pbs.twimg.com/profile_images/509365341966045184/s3PBJ9pf_normal.jpeg"}
• {"id"=>"537619237905244160", "text"=>"RT @TBI_BrainWreck: Day30 #TBIrewire \nMeditation alters gene expression and #inflammation. Try it for #TBI! \nhttp://t.co/m5tXvANaBs via @Ho…", "created_at"=>"2014-11-26T14:49:49Z", "user"=>"Rangemom1", "user_name"=>"Stephanie M Freeman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/533747483420397568/-hRZ3PJ-_normal.jpeg"}
• {"id"=>"539519891272134656", "text"=>"chyll http://t.co/xDOuKOycLG", "created_at"=>"2014-12-01T20:42:20Z", "user"=>"staxwell6", "user_name"=>"staxwell", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_4_normal.png"}
• {"id"=>"565885029101105152", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... http://t.co/bwSJAdDygA", "created_at"=>"2015-02-12T14:47:59Z", "user"=>"KA_Hicks", "user_name"=>"Kimberly Hicks", "user_profile_image"=>"http://pbs.twimg.com/profile_images/493824079447617537/aP5i-n6s_normal.jpeg"}
• {"id"=>"570948070105616384", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes http://t.co/zjvkbMSdCs", "created_at"=>"2015-02-26T14:06:42Z", "user"=>"pushitool", "user_name"=>"Darkbros", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1617923625/image_normal.jpg"}
• {"id"=>"570957388360110080", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... http://t.co/rWIUhDqli7", "created_at"=>"2015-02-26T14:43:43Z", "user"=>"pushitool", "user_name"=>"Darkbros", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1617923625/image_normal.jpg"}
• {"id"=>"602078292187951104", "text"=>"RT @BreathGuru: Breathing effects insulin secretion.\nhttp://t.co/jgAfwd8hT9 #insulin #education #Breathe", "created_at"=>"2015-05-23T11:47:05Z", "user"=>"fdevito", "user_name"=>"Fred DeVito", "user_profile_image"=>"http://pbs.twimg.com/profile_images/593353440857817088/zKFpDGym_normal.jpg"}
• {"id"=>"607725768618082304", "text"=>"For the scientist in you proving that Yoga works! http://t.co/Mu8ZIplTfR", "created_at"=>"2015-06-08T01:48:08Z", "user"=>"Yoga_RX", "user_name"=>"Caroline McCarter", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1126398269/about_caroline1_normal.jpg"}
• {"id"=>"628289277810614272", "text"=>"#PLOSONE: #Relaxation Response Induces Gene Expression Changes in Energy Metabolism, Insulin Secretion, Inflammation http://t.co/ZxfA5HgDSJ", "created_at"=>"2015-08-03T19:40:11Z", "user"=>"WMSOA", "user_name"=>"Bradley Bongiovanni", "user_profile_image"=>"http://pbs.twimg.com/profile_images/510412761445048320/Kyx7t9Bz_normal.jpeg"}
• {"id"=>"647498172969918465", "text"=>"#AMR2015 Meditation Induces Temporal Transcriptome Changes in Metabolism, Insulin Secretion & Inflammatory Pathways http://t.co/UvqmNX4gvI", "created_at"=>"2015-09-25T19:49:29Z", "user"=>"ethna7", "user_name"=>"Ethna", "user_profile_image"=>"http://pbs.twimg.com/profile_images/552604802153459712/tauH21Pe_normal.jpeg"}
• {"id"=>"662070269742342144", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... https://t.co/2E6ep4aLyo", "created_at"=>"2015-11-05T00:53:47Z", "user"=>"AllisonDaurio", "user_name"=>"Allison Daurio", "user_profile_image"=>"http://pbs.twimg.com/profile_images/649567944402276352/z2kqoBqS_normal.jpg"}
• {"id"=>"662364794532601857", "text"=>"La repetición de las palabras Paz y Amor modifica la expresión genética en el cerebro,se modera el estrés emocional https://t.co/XMIlCqVMRo", "created_at"=>"2015-11-05T20:24:07Z", "user"=>"ElJardindeJunio", "user_name"=>"El Jardín de Junio", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1592738876/Logo_color_normal.png"}
• {"id"=>"666249562575740928", "text"=>"RT @ElJardindeJunio: La repetición de las palabras Paz y Amor modifica la expresión genética en el cerebro,se modera el estrés emocional h…", "created_at"=>"2015-11-16T13:40:48Z", "user"=>"pulsAccion", "user_name"=>"PULSACCION", "user_profile_image"=>"http://pbs.twimg.com/profile_images/600677777327726592/NvKIRgv2_normal.jpg"}
• {"id"=>"668101491882790912", "text"=>"https://t.co/kDb7UUgPMN", "created_at"=>"2015-11-21T16:19:43Z", "user"=>"ALEXTORREMD", "user_name"=>"ALEJANDRO TORRE", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000018704408/cc1fab3a7c6a62089fa463c8fe9cf71b_normal.jpeg"}
• {"id"=>"684536335168716801", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... https://t.co/ZB1nfekD6x", "created_at"=>"2016-01-06T00:45:55Z", "user"=>"vedantayurveda", "user_name"=>"Vedanta Ayurveda", "user_profile_image"=>"http://pbs.twimg.com/profile_images/600281712153755649/2Pg4XHev_normal.jpg"}
• {"id"=>"698299285243170816", "text"=>"Evidence: Relaxation response associated with reduced inflammation https://t.co/EB6hxEuZpz\n#sxsw16 @sxsw #hacktoheal https://t.co/49U9F3CBSW", "created_at"=>"2016-02-13T00:14:58Z", "user"=>"DrBonnie360", "user_name"=>"Bonnie Feldman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/532615477801934848/CWJfAjvS_normal.png"}
• {"id"=>"717750722381545472", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... https://t.co/I9CPwhvFvM", "created_at"=>"2016-04-06T16:28:02Z", "user"=>"AnuragICAR", "user_name"=>"Anurag chaurasia", "user_profile_image"=>"http://pbs.twimg.com/profile_images/470819777443676160/h2ZOZ-c2_normal.jpeg"}
• {"id"=>"739109218851164161", "text"=>"#PLOSONE: Relaxation Response Induces Temporal #TranscriptomeChanges in #EnergyMetabolism, Insulin Se.. https://t.co/Yh5g41ZCV5 via @PLOSONE", "created_at"=>"2016-06-04T14:59:04Z", "user"=>"BlaKiss4", "user_name"=>"B?la Kiss", "user_profile_image"=>"http://pbs.twimg.com/profile_images/688828669289041921/qfr96QQb_normal.jpg"}
• {"id"=>"780805669997932544", "text"=>"#PLOSONE: 15 minutes’ meditation had immediate effects on the expression of genes https://t.co/yfVnniOhIm #yoga #academic #dailypractice", "created_at"=>"2016-09-27T16:25:53Z", "user"=>"bonnienewman", "user_name"=>"Bonnie Newman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/774197933784825856/di_nNKb-_normal.jpg"}
• {"id"=>"784958086440103936", "text"=>"Here is the article referenced by @JoelAndersonPhD in his keynote today on PNI at #HBB2016. #HealingTouch #healing https://t.co/pBalzSSM33", "created_at"=>"2016-10-09T03:26:06Z", "user"=>"HealingByndBdr", "user_name"=>"HealingBeyondBorders", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000787101073/474b8c2eb7e3bba31225c5dc6702608f_normal.jpeg"}
• {"id"=>"785511000371933184", "text"=>"https://t.co/HrJuHphE9B\n#HBB2016 #", "created_at"=>"2016-10-10T16:03:11Z", "user"=>"DebiSimonCHTP", "user_name"=>"Debi Simon", "user_profile_image"=>"http://pbs.twimg.com/profile_images/650508910382739456/4HQcHRth_normal.jpg"}
• {"id"=>"805208780497678336", "text"=>"How breath work modulates physiology, great sources at the end https://t.co/q4dL9KPoQ8\nhttps://t.co/mYv1w6pCo7\nhttps://t.co/XsHwMDGR8d", "created_at"=>"2016-12-04T00:35:07Z", "user"=>"DrLoBisco", "user_name"=>"Dr. LoBisco", "user_profile_image"=>"http://pbs.twimg.com/profile_images/692540891131691008/q39jpOXM_normal.jpg"}
• {"id"=>"823849155705663489", "text"=>"The #epigenetics of #relaxation- Temporal Transcriptome Changes in Metabolism, Insulin and Inflammatory Pathways https://t.co/XsHwMDGR8d", "created_at"=>"2017-01-24T11:05:19Z", "user"=>"DrLoBisco", "user_name"=>"Dr. LoBisco", "user_profile_image"=>"http://pbs.twimg.com/profile_images/692540891131691008/q39jpOXM_normal.jpg"}
• {"id"=>"897477157944909824", "text"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and... https://t.co/GnrWCldqnG", "created_at"=>"2017-08-15T15:16:43Z", "user"=>"wahyuwei", "user_name"=>"wahyu", "user_profile_image"=>"http://pbs.twimg.com/profile_images/711153218940612608/3ykPCTEX_normal.jpg"}
• {"id"=>"946494984412315648", "text"=>"#PLOSONE: Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion ... https://t.co/nnTDnZkIlO", "created_at"=>"2017-12-28T21:36:03Z", "user"=>"DeannaLRobinson", "user_name"=>"Deanna L. Robinson", "user_profile_image"=>"http://pbs.twimg.com/profile_images/678016310115098624/KPMd8xLT_normal.jpg"}

Wikipedia | Further Information

• {"title"=>"Medytacja", "url"=>"http://pl.wikipedia.org/wiki/Medytacja", "timestamp"=>"2019-03-09T23:01:20Z"}

Wordpress.com | Further Information

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• {"month"=>"5", "year"=>"2013", "pdf_views"=>"1181", "xml_views"=>"20", "html_views"=>"13843"}
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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/1050523"], "description"=>"<p>A) Differentially expressed genes identified by 3 across-group comparisons (N1 vs. N2, N1 vs. M, and N2 vs. M) at T0, T1 and T2. Venn diagrams depict the overlap of genes identified by these 3 comparisons at each time point. B) Heat map of genes that were significantly differentially expressed comparing N1 vs. N2 and N1 vs. M at T1 and T2 (marked with arrow in Venn diagrams). Gene expression is shown with a pseudocolor scale (−1 to 1) with red color denoting increased and green color denoting decreased fold change in gene expression. The rows represent the genes and columns represent subjects in N1, N2 and M groups at T0, T1 and T2. C) Differentially expressed genes identified by 3 within-group comparisons at different time points (T0 vs. T1, T0 vs. T2 and T1 vs. T2). Venn diagrams depict the overlap of genes identified by the 3 comparisons within each group.</p>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "gene-based", "differential"], "article_id"=>695424, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0062817.g001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Individual_gene_based_differential_expression_analysis_/695424", "title"=>"Individual gene-based differential expression analysis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-05-01 01:30:24"}
• {"files"=>["https://ndownloader.figshare.com/files/1050532"], "description"=>"<p>The figure represents the top focus genes. A) Progressive upregulated Pathways, B) Progressive downregulated Pathways, and C) Integrated network of Long-term and Progressive affected pathways. The top focus hubs were identified from complex interactive networks generated from pathways with progressive and long-term patterns. The focus gene hubs were identified using the bottleneck algorithm for identification of the most interactive molecules with tree like topological structure. The bottleneck algorithm ranks genes on the basis of significance level with smaller rank indicating increasing confidence. The pseudocolor scale from red to green represents the bottleneck ranks from 1 to 20.</p>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "hubs", "affected"], "article_id"=>695431, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0062817.g005", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Interactive_network_and_top_focus_gene_hubs_identified_from_significantly_affected_pathways_/695431", "title"=>"Interactive network and top focus gene hubs identified from significantly affected pathways.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-05-01 01:30:31"}
• {"files"=>["https://ndownloader.figshare.com/files/1050528"], "description"=>"<p>A) Upregulated Pathways B) Downregulated Pathways. The solid dots indicate significantly affected pathways (False Discovery Rate <25%) identified from across group comparisons (N1 vs. N2, N1 vs. M and N2 vs. M) at a particular time point (T0, T1 and T2). The asterisks represent significance and directionality of enrichment (P value<0.09 *, P value<0.05 **, P value<0.01 ***) identified from within group comparisons at different time points (T0 vs. T1, T0 vs. T2, T1 vs. T2). The red and green color asterisks indicate up- and down-regulated enrichment of pathways respectively. The heatmaps depicting relative expression of selected genes from representative pathways are shown in panels on the right side. Gene expression is shown with a pseudo color scale (−3 to 3) with red and green colors denoting increased and decreased relative expression respectively. Pathways with progressive patterns were enriched (up- or down- regulated) in N2 and M groups with greater significance of enrichments in M group. Furthermore, increasing enrichment over time within one session of RR elicitation was observed in M group.</p>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "enriched", "pathways", "patterns", "enrichment"], "article_id"=>695427, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0062817.g003", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Significantly_enriched_pathways_with_progressive_patterns_identified_using_gene_set_enrichment_analysis_/695427", "title"=>"Significantly enriched pathways with progressive patterns identified using gene set enrichment analysis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-05-01 01:30:27"}
• {"files"=>["https://ndownloader.figshare.com/files/1050536", "https://ndownloader.figshare.com/files/1050537", "https://ndownloader.figshare.com/files/1050538", "https://ndownloader.figshare.com/files/1050540", "https://ndownloader.figshare.com/files/1050541", "https://ndownloader.figshare.com/files/1050546", "https://ndownloader.figshare.com/files/1050548", "https://ndownloader.figshare.com/files/1050550", "https://ndownloader.figshare.com/files/1050551", "https://ndownloader.figshare.com/files/1050552"], "description"=>"<div><p>The relaxation response (RR) is the counterpart of the stress response. Millennia-old practices evoking the RR include meditation, yoga and repetitive prayer. Although RR elicitation is an effective therapeutic intervention that counteracts the adverse clinical effects of stress in disorders including hypertension, anxiety, insomnia and aging, the underlying molecular mechanisms that explain these clinical benefits remain undetermined. To assess rapid time-dependent (temporal) genomic changes during one session of RR practice among healthy practitioners with years of RR practice and also in novices before and after 8 weeks of RR training, we measured the transcriptome in peripheral blood prior to, immediately after, and 15 minutes after listening to an RR-eliciting or a health education CD. Both short-term and long-term practitioners evoked significant temporal gene expression changes with greater significance in the latter as compared to novices. RR practice enhanced expression of genes associated with energy metabolism, mitochondrial function, insulin secretion and telomere maintenance, and reduced expression of genes linked to inflammatory response and stress-related pathways. Interactive network analyses of RR-affected pathways identified mitochondrial ATP synthase and insulin (INS) as top upregulated critical molecules (focus hubs) and NF-κB pathway genes as top downregulated focus hubs. Our results for the first time indicate that RR elicitation, particularly after long-term practice, may evoke its downstream health benefits by improving mitochondrial energy production and utilization and thus promoting mitochondrial resiliency through upregulation of ATPase and insulin function. Mitochondrial resiliency might also be promoted by RR-induced downregulation of NF-κB-associated upstream and downstream targets that mitigates stress.</p></div>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "temporal", "transcriptome", "insulin", "secretion", "inflammatory"], "article_id"=>695435, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0062817.s001", "https://dx.doi.org/10.1371/journal.pone.0062817.s002", "https://dx.doi.org/10.1371/journal.pone.0062817.s003", "https://dx.doi.org/10.1371/journal.pone.0062817.s004", "https://dx.doi.org/10.1371/journal.pone.0062817.s005", "https://dx.doi.org/10.1371/journal.pone.0062817.s006", "https://dx.doi.org/10.1371/journal.pone.0062817.s007", "https://dx.doi.org/10.1371/journal.pone.0062817.s008", "https://dx.doi.org/10.1371/journal.pone.0062817.s009", "https://dx.doi.org/10.1371/journal.pone.0062817.s010"], "stats"=>{"downloads"=>0, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Relaxation_Response_Induces_Temporal_Transcriptome_Changes_in_Energy_Metabolism_Insulin_Secretion_and_Inflammatory_Pathways_/695435", "title"=>"Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2013-05-01 01:30:35"}
• {"files"=>["https://ndownloader.figshare.com/files/1050530"], "description"=>"<p>A) Upregulated Pathways B) Downregulated Pathways. The solid dots indicate significantly affected pathways (False Discovery Rate <25%) identified from across group comparisons (N1 vs. N2, N1 vs. M and N2 vs. M) at a particular time point (T0, T1 and T2). The asterisks represent significance and directionality of enrichment (P value<0.09 *, P value<0.05 **, P value<0.01 ***) identified from within group comparisons at different time points (T0 vs. T1, T0 vs. T2, T1 vs. T2). The red and green color asterisks indicate up- and down-regulated enrichment of pathways respectively. The heatmaps depicting relative expression of selected genes from representative pathways are shown in panels on the right side. Gene expression is shown with a pseudo color scale (−3 to 3) with red and green colors denoting increased and decreased relative expression respectively. Pathways with long-term patterns were enriched (up- or down- regulated) only in M group. Furthermore, increasing enrichment over time within one session of RR elicitation was observed in M group.</p>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "enriched", "pathways", "patterns", "enrichment"], "article_id"=>695429, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0062817.g004", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Significantly_enriched_pathways_with_long_term_patterns_identified_using_gene_set_enrichment_analysis_/695429", "title"=>"Significantly enriched pathways with long-term patterns identified using gene set enrichment analysis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-05-01 01:30:29"}
• {"files"=>["https://ndownloader.figshare.com/files/1050525"], "description"=>"<p>Genes that were differentially expressed either across or within groups comparisons at different time points were used as the seed set of genes for Self-Organizing Map (SOM) analysis. These differentially expressed genes were partitioned to 18 separate maps according to Pearson correlation coefficient based distance metrics (<a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062817#pone.0062817.s002\" target=\"_blank\">Figure S2</a>). Selected biologically interesting SOM maps were manually clustered into 4 biologically relevant categories based on the gene expression of N1, N2 and M groups at the 3 time points in one session of RR elicitation: Long-term Downregulation; Long-term Upregulation; Progressive Upregulation; and Progressive Downregulation. One representative pattern for each of these 4 biologically relevant categories is shown in the figure. The figure displays the box plot of the gene expression with X-axis representing time points and groups, and Y-axis representing scaled gene expression data from −1 to +1.</p>", "links"=>[], "tags"=>["Anatomy and physiology", "Physiological processes", "Energy metabolism", "Biochemistry", "Bioenergetics", "Energy-producing organelles", "Computational biology", "genomics", "Genome analysis tools", "transcriptomes", "Molecular cell biology", "Signal transduction", "Signaling cascades", "Insulin signaling cascade", "genomic", "patterns", "rr"], "article_id"=>695425, "categories"=>["Biological Sciences"], "users"=>["Manoj K. Bhasin", "Jeffery A. Dusek", "Bei-Hung Chang", "Marie G. Joseph", "John W. Denninger", "Gregory L. Fricchione", "Herbert Benson", "Towia A. Libermann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0062817.g002", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Temporal_genomic_expression_patterns_during_one_session_of_RR_elicitation_/695425", "title"=>"Temporal genomic expression patterns during one session of RR elicitation.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-05-01 01:30:25"}

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