Efficacy of Eye-Movement Desensitization and Reprocessing for Patients with Posttraumatic-Stress Disorder: A Meta-Analysis of Randomized Controlled Trials
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{"title"=>"Efficacy of eye-movement desensitization and reprocessing for patients with posttraumatic-stress disorder: A meta-analysis of randomized controlled trials", "type"=>"journal", "authors"=>[{"first_name"=>"Ying Ren", "last_name"=>"Chen", "scopus_author_id"=>"56073234300"}, {"first_name"=>"Kuo Wei", "last_name"=>"Hung", "scopus_author_id"=>"57200785063"}, {"first_name"=>"Jui Chen", "last_name"=>"Tsai", "scopus_author_id"=>"36806369500"}, {"first_name"=>"Hsin", "last_name"=>"Chu", "scopus_author_id"=>"55213709700"}, {"first_name"=>"Min Huey", "last_name"=>"Chung", "scopus_author_id"=>"22953113600"}, {"first_name"=>"Su Ru", "last_name"=>"Chen", "scopus_author_id"=>"8859481600"}, {"first_name"=>"Yuan Mei", "last_name"=>"Liao", "scopus_author_id"=>"26660155800"}, {"first_name"=>"Keng Liang", "last_name"=>"Ou", "scopus_author_id"=>"55660541800"}, {"first_name"=>"Yue Cune", "last_name"=>"Chang", "scopus_author_id"=>"7501842935"}, {"first_name"=>"Kuei Ru", "last_name"=>"Chou", "scopus_author_id"=>"7201905361"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"373700988", "sgr"=>"84905435380", "issn"=>"19326203", "pmid"=>"25101684", "scopus"=>"2-s2.0-84905435380", "doi"=>"10.1371/journal.pone.0103676", "isbn"=>"1932-6203"}, "id"=>"bbcc3416-f4e3-3e1f-bae0-bbc530cf711e", "abstract"=>"BACKGROUND: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.\\nMETHODS: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.\\nRESULTS: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.\\nCONCLUSION: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.", "link"=>"http://www.mendeley.com/research/efficacy-eyemovement-desensitization-reprocessing-patients-posttraumaticstress-disorder-metaanalysis", "reader_count"=>122, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>3, "Librarian"=>2, "Researcher"=>18, "Student > Doctoral Student"=>14, "Student > Ph. D. Student"=>17, "Student > Postgraduate"=>7, "Student > Master"=>23, "Other"=>6, "Student > Bachelor"=>20, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>5, "Professor > Associate Professor"=>3, "Librarian"=>2, "Researcher"=>18, "Student > Doctoral Student"=>14, "Student > Ph. D. Student"=>17, "Student > Postgraduate"=>7, "Student > Master"=>23, "Other"=>6, "Student > Bachelor"=>20, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>9, "Engineering"=>2, "Nursing and Health Professions"=>1, "Biochemistry, Genetics and Molecular Biology"=>1, "Medicine and Dentistry"=>28, "Agricultural and Biological Sciences"=>4, "Neuroscience"=>3, "Arts and Humanities"=>1, "Physics and Astronomy"=>1, "Psychology"=>67, "Social Sciences"=>4, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>2}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>28}, "Neuroscience"=>{"Neuroscience"=>3}, "Social Sciences"=>{"Social Sciences"=>4}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>67}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>4}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Unspecified"=>{"Unspecified"=>9}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"Netherlands"=>1, "United States"=>2, "United Kingdom"=>2, "Italy"=>1, "Chile"=>1, "Spain"=>1}, "group_count"=>7}

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  • {"files"=>["https://ndownloader.figshare.com/files/1626889"], "description"=>"<p>Instruments: M-PTSD  =  Mississippi scale for combat-related PTSD; IES  =  Impact of Event Scale; SI-PTSD  =  Davidson's Structured Interview for PTSD; PSS-SR  =  PTSD Symptom Scale, Self-Report; CAPS  =  Clinician-Administered PTSD Scale; PCL-C  =  PTSD Checklist; SR  =  self-report; Child PTS-RI  =  Child Posttraumatic Stress Reaction Index; CROPS  =  Child Report of Posttraumatic Symptoms; PENN  =  Penn Inventory for Posttraumatic Stress Disorder; CRI  =  Children's Reaction Inventory; PTSS-C  =  Posttraumatic Stress Symptom Scale for Children; HRSD =  The 17-item Hamilton Rating Scale for Depression; BDI =  Beck Depression Inventory; HADS-A =  the Hospital Anxiety and Depression Scale –Anxiety; HADS-D =  the Hospital Anxiety and Depression Scale – Depression; MADRS =  The Montgomery–Åsberg Depression Rating Scale; CDI =  The Children's Depression Inventory; HAMA-A =  the Hospital Anxiety and Hamilton Anxiety Scale–Anxiety; HAMA-D =  the Hospital Anxiety and Hamilton Anxiety Scale–Depression; CDS =  Children's Depression Scale; BAI =  Beck Anxiety Inventory; STAI =  State-Trait Anxiety Inventory.</p><p>Intervention: AEM  =  automated EMD; AVA  =  active visual attention; IHT  =  image habituation training; AMR  =  applied muscle relaxation; REDDR  =  EMDR treatment minus the eye movements; SPS  =  standard psychiatric support; AL  =  active listening; E + CR  =  exposure combined with cognitive restructuring; PE  =  prolonged exposure; SITPE  =  stress inoculation training with prolonged exposure; EFD  =  eye fixation desensitization; CBT  =  cognitive behavioral therapy; EFT  =  emotional freedom techniques; SC  =  standard care; WL = : waiting list; TTP  =  trauma treatment protocol; SMP  =  a standard stress management program.</p><p>Patients/Group characterization: T/C  =  treatment group/control group.</p><p>Cochrane tool: AA  =  adequacy of sequence allocation; AC  =  allocation concealment; BAO  =  blinding of assessors and outcomes; IO  =  incomplete outcome data; SRO  =  selective reporting and other biases.</p>", "links"=>[], "tags"=>["psychology", "health care", "Mental health and psychiatry", "Research assessment", "emdr", "patients", "ptsd", "randomized", "controlled", "trials", "included", "meta-analysis"], "article_id"=>1131852, "categories"=>["Biological Sciences", "Science Policy"], "users"=>["Ying-Ren Chen", "Kuo-Wei Hung", "Jui-Chen Tsai", "Hsin Chu", "Min-Huey Chung", "Su-Ru Chen", "Yuan-Mei Liao", "Keng-Liang Ou", "Yue-Cune Chang", "Kuei-Ru Chou"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0103676.t001", "stats"=>{"downloads"=>1, "page_views"=>20, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_EMDR_for_patients_with_PTSD_of_the_randomized_controlled_trials_RCTs_included_in_the_meta_analysis_N_26_/1131852", "title"=>"Characteristics of EMDR for patients with PTSD of the randomized controlled trials (RCTs) included in the meta-analysis (<i>N</i> = 26).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-07 03:33:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/1626890"], "description"=>"<p><i>P<sub>A</sub></i>, subgroup effect on outcome variable; <i>P<sub>B</sub></i>, heterogeneity among subgroups (moderator); CI, confidence interval.</p>", "links"=>[], "tags"=>["psychology", "health care", "Mental health and psychiatry", "Research assessment", "posttraumatic", "symptoms"], "article_id"=>1131853, "categories"=>["Biological Sciences", "Science Policy"], "users"=>["Ying-Ren Chen", "Kuo-Wei Hung", "Jui-Chen Tsai", "Hsin Chu", "Min-Huey Chung", "Su-Ru Chen", "Yuan-Mei Liao", "Keng-Liang Ou", "Yue-Cune Chang", "Kuei-Ru Chou"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0103676.t003", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Subgroup_analyses_of_posttraumatic_stress_disorder_PTSD_symptoms_and_depression_/1131853", "title"=>"Subgroup analyses of posttraumatic stress disorder (PTSD) symptoms and depression.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-07 03:33:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/1626891"], "description"=>"<p><i>P</i> values>0.001 were rounded to two digits.</p><p>CI, confidence interval.</p>", "links"=>[], "tags"=>["psychology", "health care", "Mental health and psychiatry", "Research assessment", "desensitization", "reprocessing", "posttraumatic"], "article_id"=>1131854, "categories"=>["Biological Sciences", "Science Policy"], "users"=>["Ying-Ren Chen", "Kuo-Wei Hung", "Jui-Chen Tsai", "Hsin Chu", "Min-Huey Chung", "Su-Ru Chen", "Yuan-Mei Liao", "Keng-Liang Ou", "Yue-Cune Chang", "Kuei-Ru Chou"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0103676.t002", "stats"=>{"downloads"=>2, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Overall_effect_size_of_eye_movement_desensitization_reprocessing_EMDR_for_posttraumatic_stress_disorder_PTSD_patients_/1131854", "title"=>"Overall effect size of eye movement desensitization reprocessing (EMDR) for posttraumatic stress disorder (PTSD) patients.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-07 03:33:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/1626892"], "description"=>"<p><i>P<sub>A</sub></i>, subgroup effect on outcome variable; <i>P<sub>B</sub></i>, heterogeneity among subgroups (moderator); CI, confidence in.</p>", "links"=>[], "tags"=>["psychology", "health care", "Mental health and psychiatry", "Research assessment", "subjective"], "article_id"=>1131855, "categories"=>["Biological Sciences", "Science Policy"], "users"=>["Ying-Ren Chen", "Kuo-Wei Hung", "Jui-Chen Tsai", "Hsin Chu", "Min-Huey Chung", "Su-Ru Chen", "Yuan-Mei Liao", "Keng-Liang Ou", "Yue-Cune Chang", "Kuei-Ru Chou"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0103676.t004", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Subgroup_analyses_of_anxiety_and_subjective_distress_/1131855", "title"=>"Subgroup analyses of anxiety and subjective distress.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-07 03:33:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/1626893"], "description"=>"<div><p>Background</p><p>We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.</p><p>Methods</p><p>We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.</p><p>Results</p><p>The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (<i>g</i> = −0.662; 95% confidence interval (CI): −0.887 to −0.436), depression (<i>g</i> = −0.643; 95% CI: −0.864 to −0.422), anxiety (<i>g</i> = −0.640; 95% CI: −0.890 to −0.390), and subjective distress (<i>g</i> = −0.956; 95% CI: −1.388 to −0.525) in PTSD patients.</p><p>Conclusion</p><p>This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.</p></div>", "links"=>[], "tags"=>["psychology", "health care", "Mental health and psychiatry", "Research assessment", "eye-movement", "desensitization", "reprocessing", "patients", "posttraumatic-stress", "meta-analysis", "randomized", "controlled"], "article_id"=>1131856, "categories"=>["Biological Sciences", "Science Policy"], "users"=>["Ying-Ren Chen", "Kuo-Wei Hung", "Jui-Chen Tsai", "Hsin Chu", "Min-Huey Chung", "Su-Ru Chen", "Yuan-Mei Liao", "Keng-Liang Ou", "Yue-Cune Chang", "Kuei-Ru Chou"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0103676", "stats"=>{"downloads"=>11, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Efficacy_of_Eye_Movement_Desensitization_and_Reprocessing_for_Patients_with_Posttraumatic_Stress_Disorder_A_Meta_Analysis_of_Randomized_Controlled_Trials_/1131856", "title"=>"Efficacy of Eye-Movement Desensitization and Reprocessing for Patients with Posttraumatic-Stress Disorder: A Meta-Analysis of Randomized Controlled Trials", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-07 03:33:42"}

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