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{"title"=>"The efficacy of paroxetine and placebo in treating anxiety and depression: A meta-analysis of change on the Hamilton Rating Scales", "type"=>"journal", "authors"=>[{"first_name"=>"Michael A.", "last_name"=>"Sugarman", "scopus_author_id"=>"53878577600"}, {"first_name"=>"Amy M.", "last_name"=>"Loree", "scopus_author_id"=>"26423789000"}, {"first_name"=>"Boris B.", "last_name"=>"Baltes", "scopus_author_id"=>"6603946465"}, {"first_name"=>"Emily R.", "last_name"=>"Grekin", "scopus_author_id"=>"6508043733"}, {"first_name"=>"Irving", "last_name"=>"Kirsch", "scopus_author_id"=>"7102863523"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"373852543", "sgr"=>"84929344180", "issn"=>"19326203", "pmid"=>"25162656", "scopus"=>"2-s2.0-84929344180", "doi"=>"10.1371/journal.pone.0106337", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)"}, "id"=>"c7ac1f69-a432-3073-8cc3-5d0ad2a9de69", "abstract"=>"BACKGROUND: Previous meta-analyses of published and unpublished trials indicate that antidepressants provide modest benefits compared to placebo in the treatment of depression; some have argued that these benefits are not clinically significant. However, these meta-analyses were based only on trials submitted for the initial FDA approval of the medication and were limited to those aimed at treating depression. Here, for the first time, we assess the efficacy of a selective serotonin reuptake inhibitor (SSRI) in the treatment of both anxiety and depression, using a complete data set of all published and unpublished trials sponsored by the manufacturer. METHODS AND FINDINGS: GlaxoSmithKline has been required to post the results for all sponsored clinical trials online, providing an opportunity to assess the efficacy of an SSRI (paroxetine) with a complete data set of all trials conducted. We examined the data from all placebo-controlled, double-blind trials of paroxetine that included change scores on the Hamilton Rating Scale for Anxiety (HRSA) and/or the Hamilton Rating Scale for Depression (HRSD). For the treatment of anxiety (k = 12), the efficacy difference between paroxetine and placebo was modest (d = 0.27), and independent of baseline severity of anxiety. Overall change in placebo-treated individuals replicated 79% of the magnitude of paroxetine response. Efficacy was superior for the treatment of panic disorder (d = 0.36) than for generalized anxiety disorder (d = 0.20). Published trials showed significantly larger drug-placebo differences than unpublished trials (d's = 0.32 and 0.17, respectively). In depression trials (k = 27), the benefit of paroxetine over placebo was consistent with previous meta-analyses of antidepressant efficacy (d = 0.32). CONCLUSIONS: The available empirical evidence indicates that paroxetine provides only a modest advantage over placebo in treatment of anxiety and depression. Treatment implications are discussed.", "link"=>"http://www.mendeley.com/research/efficacy-paroxetine-placebo-treating-anxiety-depression-metaanalysis-change-hamilton-rating-scales", "reader_count"=>73, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>3, "Librarian"=>1, "Researcher"=>10, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>6, "Other"=>11, "Student > Master"=>18, "Student > Bachelor"=>10, "Lecturer"=>2, "Professor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>3, "Librarian"=>1, "Researcher"=>10, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>6, "Other"=>11, "Student > Master"=>18, "Student > Bachelor"=>10, "Lecturer"=>2, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Nursing and Health Professions"=>2, "Biochemistry, Genetics and Molecular Biology"=>1, "Mathematics"=>1, "Medicine and Dentistry"=>28, "Agricultural and Biological Sciences"=>5, "Neuroscience"=>4, "Arts and Humanities"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>3, "Psychology"=>21, "Social Sciences"=>3, "Economics, Econometrics and Finance"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>28}, "Neuroscience"=>{"Neuroscience"=>4}, "Social Sciences"=>{"Social Sciences"=>3}, "Psychology"=>{"Psychology"=>21}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>5}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>3}, "Arts and Humanities"=>{"Arts and Humanities"=>2}}, "reader_count_by_country"=>{"Sweden"=>1, "Mexico"=>1, "Spain"=>1}, "group_count"=>3}

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• http://doi.org/10.3389/fpsyt.2019.00407
• http://doi.org/10.1891/1933-3196.12.2.46
• http://doi.org/10.18632/oncotarget.23891
• http://doi.org/10.3109/09638237.2016.1139071
• http://doi.org/10.1097/MD.0000000000003597
• http://doi.org/10.1172/jci.insight.93911
• http://doi.org/10.1177/1039856218810162
• http://doi.org/10.3389/fphar.2020.00275
• http://doi.org/10.1016/j.bbih.2020.100108
• http://doi.org/10.1016/j.vaccine.2016.09.029
• http://doi.org/10.1016/j.psychres.2017.04.005
• http://doi.org/10.1016/j.ebiom.2017.09.031
• http://doi.org/10.1177/1359105320948588
• http://doi.org/10.1016/j.bjan.2018.07.003
• http://doi.org/10.1016/j.bjane.2018.07.004
• http://doi.org/10.3389/fpsyg.2020.01354
• http://doi.org/10.1002/da.22737
• http://doi.org/10.1002/brb3.1712
• http://doi.org/10.1016/j.jad.2017.04.068
• http://doi.org/10.1080/14656566.2018.1472767
• http://doi.org/10.1177/2372732217740594
• http://doi.org/10.1192/bjp.bp.115.173450
• http://doi.org/10.1002/wps.20243
• http://doi.org/10.5937/PsihDan1702091K

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• {"type"=>"COMMENT", "annotationUri"=>"info:doi/10.1371/annotation/1b863a3c-68a3-4e99-a75c-3c92d6518dd2", "title"=>"Data by diagnosis please.", "body"=>"I appreciate the work by the authors in extracting the information from the GSK database about paroxetine clinical trials, and I hoped that I would be able to extract data from this for use in systematic discussions of the GAD evidence base, particularly as they have been able to find all the trials, not merely those published and/or with results in the open clinical trials databases. Most other meta analyses that have been published seem to have pooled effect sizes for the Hamilton Anxiety Scale in the small to medium range, which is what these trials appear to show. \n\nHowever, the authors have combined trials across the treatment groups. Have they considered the effect sizes by diagnostic group. Have the authors considered this analysis? ", "isRemoved"=>false, "created"=>"2015-03-22T08:44:57Z", "lastModified"=>"2015-03-22T08:44:57Z", "creator"=>{"userId"=>"501944"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>true, "body"=>"Member of the RANZCP Clinical Guidelines Group for GAD."}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0106337", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>1, "mostRecentActivity"=>"2015-03-23T16:26:09Z", "replies"=>[{"type"=>"REPLY", "parentID"=>85720, "annotationUri"=>"info:doi/10.1371/reply/9173f029-5cad-4e49-8e4f-a6f0853647f9", "title"=>"RE: Data by diagnosis please.", "body"=>"Thank you for your interest in the article. In response to your question, the top half of Table 3 shows the results organized by diagnosis. As shown, the paroxetine-placebo difference was smaller for GAD than panic disorder, although the overall pre-post effect sizes were larger for GAD in both paroxetine and placebo. Thus, paroxetine does not provide a very large benefit for GAD, although GAD appears to be very receptive to treatment/placebo effects.\n\nBest,\nMike Sugarman", "isRemoved"=>false, "created"=>"2015-03-23T16:26:09Z", "lastModified"=>"2015-03-23T16:26:09Z", "creator"=>{"userId"=>"502087"}, "highlightedText"=>"", "competingInterestStatement"=>{"creatorWasPrompted"=>true, "hasCompetingInterests"=>false}, "parentArticle"=>{"doi"=>"info:doi/10.1371/journal.pone.0106337", "state"=>"published", "journals"=>{"PLoSONE"=>{"journalKey"=>"PLoSONE", "eIssn"=>"1932-6203", "title"=>"PLOS ONE"}}}, "replyTreeSize"=>0, "mostRecentActivity"=>"2015-03-23T16:26:09Z", "replies"=>[]}]}

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• {"id"=>"1271566161541562368", "text"=>"https://t.co/kEnTikOsMU", "created_at"=>"2020-06-12T22:12:52Z", "user"=>"Earth2Mother", "user_name"=>"Stephen Szawlowski", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1241525416407584768/_LDCOl9-_normal.jpg"}
• {"id"=>"504863417006428160", "text"=>"製薬会社が持っているすべての臨床試験のデータでSSRIの効果を検証したメタ分析。The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: http://t.co/Ebs7KNWsUp", "created_at"=>"2014-08-28T05:29:53Z", "user"=>"uranus_2", "user_name"=>"マーキュリー２世", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_5_normal.png"}
• {"id"=>"504891489022136320", "text"=>"another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety http://t.co/EoeIGm27kO", "created_at"=>"2014-08-28T07:21:26Z", "user"=>"JoannaMoncrieff", "user_name"=>"Joanna Moncrieff", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000771624190/14ef18e6fb92ddc1388dab6060f8d1f6_normal.jpeg"}
• {"id"=>"504891571310186496", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:21:45Z", "user"=>"PeteSanders51", "user_name"=>"Pete Sanders", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1383053063/sandersportraitcol_normal.jpg"}
• {"id"=>"504891687723098113", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:22:13Z", "user"=>"steveflatt", "user_name"=>"steve flatt", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2159562221/pic_1__normal.jpg"}
• {"id"=>"504892987277852672", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:27:23Z", "user"=>"redfoxcountry", "user_name"=>"Vulpes Vulpes", "user_profile_image"=>"http://pbs.twimg.com/profile_images/497811933882351616/eU5rHZX-_normal.jpeg"}
• {"id"=>"504893326974537728", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:28:44Z", "user"=>"fbcounselling", "user_name"=>"Andrew Richardson", "user_profile_image"=>"http://pbs.twimg.com/profile_images/463071627865911296/7Z351mLw_normal.jpeg"}
• {"id"=>"504895139656257536", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:35:56Z", "user"=>"AngiePedley", "user_name"=>"Angie Pedley", "user_profile_image"=>"http://pbs.twimg.com/profile_images/437697840987398144/KmLdLQKw_normal.jpeg"}
• {"id"=>"504895512202719232", "text"=>"Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/OGcP0Plz7T", "created_at"=>"2014-08-28T07:37:25Z", "user"=>"joarhalvorsen", "user_name"=>"Joar Ø. Halvorsen", "user_profile_image"=>"http://pbs.twimg.com/profile_images/482446990530191360/v2eErPZ1_normal.jpeg"}
• {"id"=>"504896401344835584", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T07:40:57Z", "user"=>"in_psych", "user_name"=>"Joe Hayes", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1671176713/joe_normal.jpg"}
• {"id"=>"504896940782682112", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:43:05Z", "user"=>"SusieBloor", "user_name"=>"Susie Bloor", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2326317887/mq5yrxj9sp7djx2dy001_normal.jpeg"}
• {"id"=>"504897315384332288", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:44:35Z", "user"=>"AJGoudie", "user_name"=>" A Goudie", "user_profile_image"=>"http://pbs.twimg.com/profile_images/459272810498490370/LZa_Gppb_normal.jpeg"}
• {"id"=>"504899207460057088", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T07:52:06Z", "user"=>"psychMDtobe", "user_name"=>"Lucy van Pelt", "user_profile_image"=>"http://pbs.twimg.com/profile_images/487489291157647361/7JucU0vC_normal.jpeg"}
• {"id"=>"504901336794935297", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T08:00:33Z", "user"=>"mdimairo", "user_name"=>"Munya", "user_profile_image"=>"http://pbs.twimg.com/profile_images/471054822587006976/5G5mPpmM_normal.jpeg"}
• {"id"=>"504902615185235968", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T08:05:38Z", "user"=>"ihgcounselling", "user_name"=>"Angela Emmerson", "user_profile_image"=>"http://pbs.twimg.com/profile_images/464668736834646016/40U9mVxh_normal.jpeg"}
• {"id"=>"504910507275337729", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T08:37:00Z", "user"=>"Dyregrov", "user_name"=>"Atle Dyregrov", "user_profile_image"=>"http://pbs.twimg.com/profile_images/196403059/Pass_forminsket_2_normal.jpg"}
• {"id"=>"504911719702224896", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T08:41:49Z", "user"=>"Walrathis", "user_name"=>"Andrea", "user_profile_image"=>"http://pbs.twimg.com/profile_images/496640066375008256/glELJZmN_normal.jpeg"}
• {"id"=>"504928155673829376", "text"=>"plus ça change MT @joarhalvorsen via @mdimairo paroxetine #clinicaltrials effects sig diff: Published>unpublished http://t.co/a4x7gB2Lj1", "created_at"=>"2014-08-28T09:47:08Z", "user"=>"robertstats", "user_name"=>"Robert Grant", "user_profile_image"=>"http://pbs.twimg.com/profile_images/482451425188782080/cE5yR2xE_normal.jpeg"}
• {"id"=>"504930321880846336", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T09:55:44Z", "user"=>"JRVaag", "user_name"=>"Jonas R Vaag", "user_profile_image"=>"http://pbs.twimg.com/profile_images/499302230672293888/ju25AxDm_normal.jpeg"}
• {"id"=>"504951478671642625", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T11:19:48Z", "user"=>"whoscrazynow", "user_name"=>"Elly Litvak", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3612621317/78336f243434b9c64ce7b1a2dee621d3_normal.jpeg"}
• {"id"=>"504952681149239297", "text"=>"RT @joarhalvorsen: Published trials of paroxetine showed significantly larger drug-placebo differences than unpublished trials http://t.co/…", "created_at"=>"2014-08-28T11:24:35Z", "user"=>"olanzapinenight", "user_name"=>"Sally Macgregor", "user_profile_image"=>"http://pbs.twimg.com/profile_images/499552672505032704/AbdA3cjb_normal.jpeg"}
• {"id"=>"504954747649294336", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T11:32:48Z", "user"=>"jose_valdecasas", "user_name"=>"Jose Valdecasas", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1184287067/20080411elpepucul_39_normal.jpg"}
• {"id"=>"504954966348685313", "text"=>"Otro metaanálisis que cuestiona eficacia antidepresivos frente a placebo en ansiedad y depresión\nhttp://t.co/Z5r2FpxysY\nvía @JoannaMoncrieff", "created_at"=>"2014-08-28T11:33:40Z", "user"=>"psiquicritic", "user_name"=>"Psiquiatría Crítica", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1899072212/lobotomia1_normal.jpg"}
• {"id"=>"504955676842803200", "text"=>"RT @psiquicritic: Otro metaanálisis que cuestiona eficacia antidepresivos frente a placebo en ansiedad y depresión\nhttp://t.co/Z5r2FpxysY\nv…", "created_at"=>"2014-08-28T11:36:29Z", "user"=>"Paulo_Mai", "user_name"=>"Paulo Henrique Mai", "user_profile_image"=>"http://pbs.twimg.com/profile_images/483000073136005120/72bLgOdI_normal.jpeg"}
• {"id"=>"504955731536519168", "text"=>"RT @psiquicritic: Otro metaanálisis que cuestiona eficacia antidepresivos frente a placebo en ansiedad y depresión\nhttp://t.co/Z5r2FpxysY\nv…", "created_at"=>"2014-08-28T11:36:42Z", "user"=>"Kano_es", "user_name"=>"Kano", "user_profile_image"=>"http://pbs.twimg.com/profile_images/489360733323268097/9ESfjHPi_normal.jpeg"}
• {"id"=>"504957413058150400", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T11:43:23Z", "user"=>"Eduardo_Barbudo", "user_name"=>"Eduardo Barbudo", "user_profile_image"=>"http://pbs.twimg.com/profile_images/467385128394559488/jleghGv7_normal.jpeg"}
• {"id"=>"504966689424158720", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T12:20:15Z", "user"=>"Eivissa73", "user_name"=>"Kate", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2857595211/1e3485dd545a37538692b8d30f6839ae_normal.png"}
• {"id"=>"504975256122298368", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T12:54:17Z", "user"=>"ElaheHessamfar", "user_name"=>"Elahe Hessamfar", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2613581665/Elahe35_normal.JPG"}
• {"id"=>"504978628476928000", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T13:07:41Z", "user"=>"aiquena", "user_name"=>"ஓ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/501235133051973633/SjIdaJK__normal.jpeg"}
• {"id"=>"504979541937623040", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T13:11:19Z", "user"=>"Stroncio7", "user_name"=>"Stroncio7", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3377850103/95900c752d114c7cae616fa891338330_normal.jpeg"}
• {"id"=>"505004780708958208", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T14:51:36Z", "user"=>"StijnVanheule", "user_name"=>"stijn vanheule", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3695145466/5b2d026041861b09096cdd4375a883ed_normal.jpeg"}
• {"id"=>"505008686419701761", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T15:07:08Z", "user"=>"PActueel", "user_name"=>"Psychoanalyt.Actueel", "user_profile_image"=>"http://pbs.twimg.com/profile_images/418786028183228416/G96y33X4_normal.png"}
• {"id"=>"505037155664945152", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T17:00:15Z", "user"=>"BizOMadness", "user_name"=>"Bonnie Burstow", "user_profile_image"=>"http://pbs.twimg.com/profile_images/474680270897963008/ezqM-u6t_normal.png"}
• {"id"=>"505044412855226368", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T17:29:05Z", "user"=>"jen_unwin", "user_name"=>"Jen Unwin", "user_profile_image"=>"http://pbs.twimg.com/profile_images/479327176731688960/8rDz-5Oq_normal.jpeg"}
• {"id"=>"505044457587486720", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T17:29:16Z", "user"=>"PTSDinfo", "user_name"=>"PTSDinfo", "user_profile_image"=>"http://pbs.twimg.com/profile_images/447550066387992576/NDuushYh_normal.jpeg"}
• {"id"=>"505052286906032128", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-28T18:00:23Z", "user"=>"CNSResponse", "user_name"=>"CNS Response", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000172228641/f3c9a8ee06232e787d31f94ac2e763ac_normal.jpeg"}
• {"id"=>"505070139327275008", "text"=>"“@JoannaMoncrieff: another meta-analysis:miniscule differences in antidepressants &placebo for depression & anxiety http://t.co/yXRmMvJKQe”", "created_at"=>"2014-08-28T19:11:19Z", "user"=>"BetsyDeChant", "user_name"=>"Betsy DeChant", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_4_normal.png"}
• {"id"=>"505644119213871106", "text"=>"RT @uranus_2: 製薬会社が持っているすべての臨床試験のデータでSSRIの効果を検証したメタ分析。The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: http://t.c…", "created_at"=>"2014-08-30T09:12:07Z", "user"=>"shirotank", "user_name"=>"shirotank", "user_profile_image"=>"http://pbs.twimg.com/profile_images/797064612/filename-_iso-2022-jp___1B_B-L_3F_3F_1B_B__1__normal.jpg"}
• {"id"=>"505730565618692096", "text"=>"#グラクソスミスクライン の #パキシル 、うつ病や不安症でのプラセボを超えるベネフィットはごくわずか―公表されているデータに、未公表データを加えたメタアナリシスにより判明　August 27, 2014　Plos ONE 掲載論文　http://t.co/fDH2NWNlAN", "created_at"=>"2014-08-30T14:55:37Z", "user"=>"anntocoo", "user_name"=>"scott walker", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_6_normal.png"}
• {"id"=>"505740010340233216", "text"=>"New evidence of limits of antidepressants \n http://t.co/glGvV0m8ZV", "created_at"=>"2014-08-30T15:33:09Z", "user"=>"DrScottBishop", "user_name"=>"Dr. Scott R Bishop", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1368735647/143017_normal.jpg"}
• {"id"=>"505757103386931200", "text"=>"RT @uranus_2: 製薬会社が持っているすべての臨床試験のデータでSSRIの効果を検証したメタ分析。The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: http://t.c…", "created_at"=>"2014-08-30T16:41:04Z", "user"=>"annpannmann2011", "user_name"=>"anpanman", "user_profile_image"=>"http://pbs.twimg.com/profile_images/475104765462859776/A7JXfyhC_normal.png"}
• {"id"=>"505787922302263296", "text"=>"#PLOSONE: The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: A Meta-Ana H... http://t.co/03FNoDATO0", "created_at"=>"2014-08-30T18:43:32Z", "user"=>"DocHeuer", "user_name"=>"MARV HEUER", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1720178556/Headshot_cropped_normal.jpg"}
• {"id"=>"505830165516001280", "text"=>"RT @anntocoo: #グラクソスミスクライン の #パキシル 、うつ病や不安症でのプラセボを超えるベネフィットはごくわずか―公表されているデータに、未公表データを加えたメタアナリシスにより判明　August 27, 2014　Plos ONE 掲載論文　http://t…", "created_at"=>"2014-08-30T21:31:24Z", "user"=>"Tosaka4398", "user_name"=>"精神科の薬は使われすぎ＆評価されすぎ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/453806415589556224/z1601suY_normal.jpeg"}
• {"id"=>"505942810478911488", "text"=>"The Efficacy of #Paroxetine and Placebo in Treating Anxiety and Depression: A Meta-Analysis... http://t.co/R5NlyYlYBg #HAM-D #GSK #PLOSONE", "created_at"=>"2014-08-31T04:59:00Z", "user"=>"psychepi", "user_name"=>"Melissa Raven", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1590827147/cockatoo_flying_clouds_cropped2_normal.JPG"}
• {"id"=>"506019362323832834", "text"=>"Evidence shows that paroxetine provides only a modest advantage over placebo in treatment of anxiety and depression. http://t.co/sU9YiGvnRI", "created_at"=>"2014-08-31T10:03:12Z", "user"=>"Fiddaman", "user_name"=>"BOB FIDDAMAN", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1939513704/fidc_normal.jpg"}
• {"id"=>"506038231402827776", "text"=>"@GSKUS's #Paxil - modest advantage over placebo - new study finds. http://t.co/sU9YiGvnRI #Pharmafia #GSK", "created_at"=>"2014-08-31T11:18:10Z", "user"=>"Fiddaman", "user_name"=>"BOB FIDDAMAN", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1939513704/fidc_normal.jpg"}
• {"id"=>"506052077693718528", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-08-31T12:13:11Z", "user"=>"GBCounsellor", "user_name"=>"Gaynor Boileau", "user_profile_image"=>"http://pbs.twimg.com/profile_images/424265925445971968/0N6QoW4h_normal.png"}
• {"id"=>"506160796577964032", "text"=>"http://t.co/cK0aPmYZWI\nThe Emperor's New Drugs redux--just say no to Paxil.", "created_at"=>"2014-08-31T19:25:12Z", "user"=>"DrCarolLow", "user_name"=>"Carol B. Low", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3078389726/c5ffd80aa22d1583f9921305825319f1_normal.jpeg"}
• {"id"=>"506217946499125248", "text"=>"RT @anntocoo: #グラクソスミスクライン の #パキシル 、うつ病や不安症でのプラセボを超えるベネフィットはごくわずか―公表されているデータに、未公表データを加えたメタアナリシスにより判明　August 27, 2014　Plos ONE 掲載論文　http://t…", "created_at"=>"2014-08-31T23:12:18Z", "user"=>"il_CIBO", "user_name"=>"イルチーボ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/827499492/SN3D0454_normal.jpg"}
• {"id"=>"506339967367249920", "text"=>"#PLOSONE: The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: A Meta-Analysis of Change on... http://t.co/2YolJZKOB8", "created_at"=>"2014-09-01T07:17:10Z", "user"=>"Belal_Mustafa", "user_name"=>"بلال مصطفى بدران", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000788159758/0ddf9ef7d0326c5e5d6b7e0260dd1b8e_normal.jpeg"}
• {"id"=>"506522920601255937", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-01T19:24:09Z", "user"=>"AnnMarieTaylor2", "user_name"=>"Ann Marie Taylor", "user_profile_image"=>"http://pbs.twimg.com/profile_images/493620402158313472/IFFG9RSL_normal.jpeg"}
• {"id"=>"506578979441344512", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-01T23:06:55Z", "user"=>"Bfd_Psych_Drugs", "user_name"=>"Bfd Psych Drugs", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000126212951/db2731a7343a760ec9a86ba606676994_normal.jpeg"}
• {"id"=>"506581111766777858", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-01T23:15:23Z", "user"=>"TallaTrialogue", "user_name"=>"Tallaght Trialogue ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/420896961177206784/JrkiuYNS_normal.jpeg"}
• {"id"=>"506800870366130177", "text"=>"Paxil shows only minimal benefits beyond a placebo in treatment of depression and anxiety http://t.co/UeUK6m08XV", "created_at"=>"2014-09-02T13:48:38Z", "user"=>"drbobcarey", "user_name"=>"Dr. Bob Carey", "user_profile_image"=>"http://pbs.twimg.com/profile_images/478324823043497984/IsRScTlE_normal.jpeg"}
• {"id"=>"506889187132731392", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-02T19:39:34Z", "user"=>"ivaalsg", "user_name"=>"Ingrid J. Vaalund", "user_profile_image"=>"http://pbs.twimg.com/profile_images/459743678861299712/Cw1Q0vyA_normal.jpeg"}
• {"id"=>"506893806432948224", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-02T19:57:55Z", "user"=>"GarySidley", "user_name"=>"Gary Sidley", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000601880056/8d60bede3b44732f2d8623fde76bc330_normal.jpeg"}
• {"id"=>"507011391849766912", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T03:45:10Z", "user"=>"THEAGENTAPSLEY", "user_name"=>"THE AGENT APSLEY", "user_profile_image"=>"http://pbs.twimg.com/profile_images/503118043841433601/iohmIFfL_normal.jpeg"}
• {"id"=>"507101361268592640", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T09:42:40Z", "user"=>"VoicesUnLtd", "user_name"=>"INTERVOICE", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1363526932/logo-redblack1_INTERVOICE_normal.jpg"}
• {"id"=>"507104273046708224", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T09:54:14Z", "user"=>"vanessakrasinsk", "user_name"=>"Vanessa Krasinski", "user_profile_image"=>"http://pbs.twimg.com/profile_images/505466136499355651/9YZFQSjh_normal.jpeg"}
• {"id"=>"507143365058891776", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T12:29:35Z", "user"=>"psyguyots", "user_name"=>"H.D.C. Project", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000780450747/32a897de7c754abde09a291e1e6a580d_normal.jpeg"}
• {"id"=>"507144667691880449", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T12:34:45Z", "user"=>"thepsychclinic", "user_name"=>"David Ferraro", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1569331406/russian_profile_pic_normal.jpg"}
• {"id"=>"507144811628204032", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T12:35:20Z", "user"=>"headnavigator", "user_name"=>"Head Navigator", "user_profile_image"=>"http://pbs.twimg.com/profile_images/507143636849803264/OsU-LyFJ_normal.jpeg"}
• {"id"=>"507283348994424832", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-03T21:45:49Z", "user"=>"Andrew_Hozz", "user_name"=>"AndrewH", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2271648588/145eseku69ixj201jmgb_normal.jpeg"}
• {"id"=>"509267156031516673", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-09T09:08:46Z", "user"=>"barroumatt", "user_name"=>"Lucien", "user_profile_image"=>"http://pbs.twimg.com/profile_images/464748101446537216/bHmAkHBw_normal.jpeg"}
• {"id"=>"509439139112947715", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-09T20:32:10Z", "user"=>"lamiscarreb", "user_name"=>"Lamiscarre B", "user_profile_image"=>"http://pbs.twimg.com/profile_images/500663571550707715/FKPnUcDj_normal.jpeg"}
• {"id"=>"510186570755092480", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-11T22:02:11Z", "user"=>"anarcho_ted", "user_name"=>"Ted Ludd", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2868447281/aa7e7a88121cb6c7124abb7773d0533c_normal.png"}
• {"id"=>"510186838125211649", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-11T22:03:15Z", "user"=>"dronemodule", "user_name"=>"sometimes_explode", "user_profile_image"=>"http://pbs.twimg.com/profile_images/344513261572977718/c65ddce06d7aff4063e1b12adcca1f64_normal.jpeg"}
• {"id"=>"510189727769972736", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-11T22:14:44Z", "user"=>"german_sierra", "user_name"=>"German Sierra", "user_profile_image"=>"http://pbs.twimg.com/profile_images/435215226691411968/2KDdGc2G_normal.jpeg"}
• {"id"=>"510189930413563904", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-11T22:15:32Z", "user"=>"psychwatch2", "user_name"=>"vidgen", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3681682442/3a82185b6b186994993e7aa2c8eedd44_normal.jpeg"}
• {"id"=>"510344772717117440", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-12T08:30:50Z", "user"=>"deontologistics", "user_name"=>"pete wolfendale", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1304820284/Partition_invert__normal.png"}
• {"id"=>"510409079991590912", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-12T12:46:22Z", "user"=>"victorxis", "user_name"=>"Victor Marques", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1158163796/875c1713-87bb-4c36-8429-d332b2160b93_normal.jpg"}
• {"id"=>"510558709886775296", "text"=>"Proud to have been a part of this article: http://t.co/dcOszHCsUK", "created_at"=>"2014-09-12T22:40:56Z", "user"=>"applescrff", "user_name"=>"A. Lo", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3763672660/f4b8517ad9fbadbabdf7ffea168a3ea3_normal.jpeg"}
• {"id"=>"510749703491710976", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-13T11:19:53Z", "user"=>"conoilseed", "user_name"=>"Con Oilseed", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2884440573/e5595f77db1b42447fe1c121dcf53e38_normal.png"}
• {"id"=>"510898519972921344", "text"=>"#PLOSONE: The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: A Meta-Analysis http://t.co/5SxuCN9ixI", "created_at"=>"2014-09-13T21:11:13Z", "user"=>"Ygoes2B_more", "user_name"=>"yuri", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1664847466/SDC13094_normal.JPG"}
• {"id"=>"511037909651431424", "text"=>"Small is not minuscule, misleading MT@JoannaMoncrieff: miniscule differences between antidepressants and placebo http://t.co/0zOgHyGpcT", "created_at"=>"2014-09-14T06:25:06Z", "user"=>"SameiHuda", "user_name"=>"Samei Huda", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3088102350/d4a40446323592fd20962da469716015_normal.jpeg"}
• {"id"=>"511067937944657920", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-14T08:24:26Z", "user"=>"psyguyots", "user_name"=>"H.D.C. Project", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000780450747/32a897de7c754abde09a291e1e6a580d_normal.jpeg"}
• {"id"=>"511376388570746880", "text"=>"Once again a meta-analysis finds little effect of antidepressant use over the placebo http://t.co/n9X9xw6CYI", "created_at"=>"2014-09-15T04:50:06Z", "user"=>"JudibPsyD", "user_name"=>" Judith Browne, PsyD", "user_profile_image"=>"http://pbs.twimg.com/profile_images/511312245876199424/lAuwRm5F_normal.jpeg"}
• {"id"=>"512007397330911232", "text"=>"Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-16T22:37:30Z", "user"=>"MedicosSinMarca", "user_name"=>"Médicos Sin Marca", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2222563172/tw-jpg_normal.jpg"}
• {"id"=>"512009867801165824", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-16T22:47:19Z", "user"=>"patotime", "user_name"=>"Patricio Thieme", "user_profile_image"=>"http://pbs.twimg.com/profile_images/506682333131718656/hhDOfsMD_normal.jpeg"}
• {"id"=>"512010343884029952", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-16T22:49:13Z", "user"=>"SusanaQuezada2", "user_name"=>"Susana Quezada", "user_profile_image"=>"http://pbs.twimg.com/profile_images/481638553068535808/TVn0qrav_normal.jpeg"}
• {"id"=>"512039732097081344", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T00:46:00Z", "user"=>"jmanalich", "user_name"=>"Jaime Mañalich Muxi", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1537684857/Foto1_normal.jpg"}
• {"id"=>"512039941459947520", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T00:46:49Z", "user"=>"pavivina", "user_name"=>"paula vigueras", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000154212203/ba79f67e0b04bb1a42ce163cea037d84_normal.jpeg"}
• {"id"=>"512040585189150720", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T00:49:23Z", "user"=>"d1egoalarcon", "user_name"=>"Diego Alarcón", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000703833224/ac4ba180bd18943beafdb52c767c4127_normal.jpeg"}
• {"id"=>"512042035805974529", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T00:55:09Z", "user"=>"juanenriquejara", "user_name"=>"Juan Enrique Jara ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1486612210/quique_normal.png"}
• {"id"=>"512044043577348097", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T01:03:07Z", "user"=>"gaboliv", "user_name"=>"Gabriel Olivares-Laz", "user_profile_image"=>"http://pbs.twimg.com/profile_images/469182971690647552/YvVFqvDP_normal.jpeg"}
• {"id"=>"512051260577812481", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T01:31:48Z", "user"=>"carmentorrestob", "user_name"=>"carmen torres tobar", "user_profile_image"=>"http://pbs.twimg.com/profile_images/475074481245782017/_xUaDT1W_normal.jpeg"}
• {"id"=>"512056280585080832", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T01:51:45Z", "user"=>"nickihund", "user_name"=>"Nicole Hund", "user_profile_image"=>"http://pbs.twimg.com/profile_images/501563346819108864/3f3aRWP3_normal.jpeg"}
• {"id"=>"512083961993256961", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T03:41:45Z", "user"=>"chechu", "user_name"=>"Chechu", "user_profile_image"=>"http://pbs.twimg.com/profile_images/421274493/musik_in_Fi_ana_normal.jpg"}
• {"id"=>"512100601816440832", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T04:47:52Z", "user"=>"fernando_solera", "user_name"=>"Fernando Solera", "user_profile_image"=>"http://pbs.twimg.com/profile_images/490836858713038848/qmn0eGI9_normal.jpeg"}
• {"id"=>"512120423841284096", "text"=>"“@MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/SM91U2iprd”", "created_at"=>"2014-09-17T06:06:38Z", "user"=>"MorillasUrda", "user_name"=>"Manuel Morillas Urda", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2859581332/f4c36b4de271b4f6139090e2cd63297c_normal.jpeg"}
• {"id"=>"512158613369290752", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T08:38:23Z", "user"=>"carorock", "user_name"=>"Carolina Gardilcic", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000222425728/2e3b9fbb0c241a2a53c98c803f5e3598_normal.jpeg"}
• {"id"=>"512176194104864769", "text"=>"RT @MedicosSinMarca: Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/0AXlkJjmqA", "created_at"=>"2014-09-17T09:48:15Z", "user"=>"carmendiri", "user_name"=>"Carmen Martínez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3724595106/7e7e7a18d7f3b6a5e2f5e13d35ce455c_normal.jpeg"}
• {"id"=>"512670594685739008", "text"=>"Vaya!\" Al menos un 80% del efecto de la paroxetina en depresión y ansiedad es debido a la sugestión http://t.co/G8hGyTj7YM\"", "created_at"=>"2014-09-18T18:32:49Z", "user"=>"carmendiri", "user_name"=>"Carmen Martínez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3724595106/7e7e7a18d7f3b6a5e2f5e13d35ce455c_normal.jpeg"}
• {"id"=>"514016056676216833", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-22T11:39:12Z", "user"=>"NatsMFfern", "user_name"=>"Natalie F", "user_profile_image"=>"http://pbs.twimg.com/profile_images/477502892895526914/Pbg2Le_i_normal.jpeg"}
• {"id"=>"514016064418906112", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-22T11:39:14Z", "user"=>"slovestina", "user_name"=>"Slovestina", "user_profile_image"=>"http://pbs.twimg.com/profile_images/512022081639165952/AXXK7fOy_normal.jpeg"}
• {"id"=>"514017561865097216", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-22T11:45:11Z", "user"=>"CardiffHealthPs", "user_name"=>"Health Psychology ", "user_profile_image"=>"http://pbs.twimg.com/profile_images/463681262578712576/gnbw15uI_normal.jpeg"}
• {"id"=>"514060834793086977", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-22T14:37:08Z", "user"=>"CPA_Health", "user_name"=>"Health Behav Psych", "user_profile_image"=>"http://pbs.twimg.com/profile_images/476404777941606400/oyXEpB6c_normal.jpeg"}
• {"id"=>"514085392686276609", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-22T16:14:43Z", "user"=>"doc_lmw", "user_name"=>"dr. linda.wiebe", "user_profile_image"=>"http://pbs.twimg.com/profile_images/1672599000/dr.wiebe1_1322954386748_normal.jpg"}
• {"id"=>"514697281518718976", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-09-24T08:46:09Z", "user"=>"ChaoticPharma", "user_name"=>"Jorge Ramírez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/505661931479252993/DTraajWM_normal.jpeg"}
• {"id"=>"514788575381303297", "text"=>"@david_colquhoun Here it is http://t.co/fjhol0sAFU Seems spun to me", "created_at"=>"2014-09-24T14:48:55Z", "user"=>"Keith_Laws", "user_name"=>"Keith R Laws", "user_profile_image"=>"http://pbs.twimg.com/profile_images/506473743938752512/UjX4mfDP_normal.jpeg"}
• {"id"=>"519909735672205312", "text"=>"One antidepressant has modest benefits for depression and anxiety. http://t.co/upqczFqGEz #depression #anxiety", "created_at"=>"2014-10-08T17:58:35Z", "user"=>"indigorhythms", "user_name"=>"Indigo Rhythms", "user_profile_image"=>"http://pbs.twimg.com/profile_images/518136181091864576/ykplJyXl_normal.jpeg"}
• {"id"=>"521113983349035010", "text"=>"RT @Fiddaman: Evidence shows that paroxetine provides only a modest advantage over placebo in treatment of anxiety and depression. http://t…", "created_at"=>"2014-10-12T01:43:50Z", "user"=>"ekenaga", "user_name"=>"SXRISuicideJapan", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_4_normal.png"}
• {"id"=>"521410776553521152", "text"=>"RT @psiquicritic: Otro metaanálisis que cuestiona eficacia antidepresivos frente a placebo en ansiedad y depresión\nhttp://t.co/Z5r2FpxysY\nv…", "created_at"=>"2014-10-12T21:23:11Z", "user"=>"Ferpdelrio", "user_name"=>"Fernando P del Río", "user_profile_image"=>"http://pbs.twimg.com/profile_images/495036391844478976/v5HqoSGh_normal.jpeg"}
• {"id"=>"529971906359726082", "text"=>"RT @JoannaMoncrieff: another meta-analysis showing miniscule differences between antidepressants and placebo for depression and anxiety htt…", "created_at"=>"2014-11-05T12:22:03Z", "user"=>"Jaii_Raph", "user_name"=>"✩✩✩JJR✩✩✩", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000391147201/c2139370f942d50e2f6d6d06cfb9bb58_normal.png"}
• {"id"=>"529991020440993792", "text"=>"A modest advantage of antidepressant over placebo? http://t.co/SrMcJiN7DU\nvia @PLOSONE", "created_at"=>"2014-11-05T13:38:00Z", "user"=>"mrgxprz", "user_name"=>"Margaux Larre-Perez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515467927097573376/s6B_iMJj_normal.jpeg"}
• {"id"=>"529991326902001664", "text"=>"Un avantage seulement \"modeste\" des antidépresseurs sur le placébo? Une nvelle méta-analyse via @PLOSONE http://t.co/SrMcJiN7DU", "created_at"=>"2014-11-05T13:39:13Z", "user"=>"mrgxprz", "user_name"=>"Margaux Larre-Perez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515467927097573376/s6B_iMJj_normal.jpeg"}
• {"id"=>"529991760240709633", "text"=>"A modest advantage of #antidepressants over placebo? A new metanalysis \nvia @PLOSONE http://t.co/SrMcJiN7DU", "created_at"=>"2014-11-05T13:40:57Z", "user"=>"mrgxprz", "user_name"=>"Margaux Larre-Perez", "user_profile_image"=>"http://pbs.twimg.com/profile_images/515467927097573376/s6B_iMJj_normal.jpeg"}
• {"id"=>"530157003729944576", "text"=>"Paroxetine only marginally better than placebo at reducing anxiety/depression: a meta-analysis. http://t.co/e5ZsBMzLmk … (via @mrgxprz)", "created_at"=>"2014-11-06T00:37:34Z", "user"=>"ThatNeilMartin", "user_name"=>"Dr Neil Martin", "user_profile_image"=>"http://pbs.twimg.com/profile_images/526470227882553344/sD-Yc5l__normal.jpeg"}
• {"id"=>"530157055047258115", "text"=>"RT @ThatNeilMartin: Paroxetine only marginally better than placebo at reducing anxiety/depression: a meta-analysis. http://t.co/e5ZsBMzLmk …", "created_at"=>"2014-11-06T00:37:46Z", "user"=>"BelindaBG", "user_name"=>"Dr Bel Brooks-Gordon", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000797374908/6055ffc0d59c2c47196431be66f764fb_normal.jpeg"}

Wikipedia | Further Information

• {"title"=>"Paroxetine", "url"=>"http://en.wikipedia.org/wiki/Paroxetine", "timestamp"=>"2019-03-11T05:55:30Z"}
• {"title"=>"抗不安薬", "url"=>"http://ja.wikipedia.org/wiki/抗不安薬", "timestamp"=>"2019-03-01T12:17:58Z"}
• {"title"=>"パニック障害", "url"=>"http://ja.wikipedia.org/wiki/パニック障害", "timestamp"=>"2019-02-05T22:44:31Z"}
• {"title"=>"باروكسيتين", "url"=>"http://ar.wikipedia.org/wiki/باروكسيتين", "timestamp"=>"2019-02-18T14:23:29Z"}

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/1652180"], "description"=>"<p>The size of the marker reflects the relative weight of the study in the meta-analysis.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153260, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.g003", "stats"=>{"downloads"=>3, "page_views"=>46, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_severity_of_depression_and_the_mean_change_on_the_Hamilton_Rating_Scale_for_Depression_HRSD_/1153260", "title"=>"Baseline severity of depression and the mean change on the Hamilton Rating Scale for Depression (HRSD).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652174"], "description"=>"<p>The size of the marker reflects the relative weight of the study in the meta-analysis.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153254, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.g002", "stats"=>{"downloads"=>2, "page_views"=>39, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_severity_of_anxiety_and_the_mean_change_on_the_Hamilton_Rating_Scale_for_Anxiety_HRSA_/1153254", "title"=>"Baseline severity of anxiety and the mean change on the Hamilton Rating Scale for Anxiety (HRSA).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652188"], "description"=>"<p>GAD = generalized anxiety disorder.</p><p>Moderator effects in trials examining change on the Hamilton Rating Scale for Anxiety.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153268, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.t003", "stats"=>{"downloads"=>4, "page_views"=>21, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Moderator_effects_in_trials_examining_change_on_the_Hamilton_Rating_Scale_for_Anxiety_/1153268", "title"=>"Moderator effects in trials examining change on the Hamilton Rating Scale for Anxiety.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652170"], "description"=>"<p>GSK = GlaxoSmithKline, HRSA = Hamilton Rating Scale for Anxiety, HRSD = Hamilton Rating Scale for Depression. Please refer to the text for more specific information regarding specific exclusion criteria.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153250, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.g001", "stats"=>{"downloads"=>21, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Trial_selection_Flow_chart_/1153250", "title"=>"Trial selection Flow chart.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652183"], "description"=>"<p>The size of the marker reflects the relative weight of the study in the meta-analysis.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153263, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.g004", "stats"=>{"downloads"=>3, "page_views"=>31, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Trial_duration_in_weeks_and_the_mean_change_on_the_Hamilton_Rating_Scale_for_Depression_HRSD_/1153263", "title"=>"Trial duration (in weeks) and the mean change on the Hamilton Rating Scale for Depression (HRSD).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652184"], "description"=>"<p>HRSA = Hamilton Rating Scale for Anxiety. HRSD = Hamilton Rating Scale for Depression. Year: when data collection was initiated. Trials conducted prior to 1991 were submitted for the original FDA approval of the medication. Length: study duration in weeks. GAD = generalized anxiety disorder.</p><p>List of studies.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153264, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.t001", "stats"=>{"downloads"=>1, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_List_of_studies_/1153264", "title"=>"List of studies.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652193"], "description"=>"<p>Pre-approval and Post-approval refer to whether the trial was included as part of the original approval submission to the FDA (<i>k</i> = 16) or whether it was conducted following FDA approval in 1991 or later (<i>k</i> = 11).</p><p>Moderator effects in trials examining change on the Hamilton Rating Scale for Depression.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153273, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.t005", "stats"=>{"downloads"=>2, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Moderator_effects_in_trials_examining_change_on_the_Hamilton_Rating_Scale_for_Depression_/1153273", "title"=>"Moderator effects in trials examining change on the Hamilton Rating Scale for Depression.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652192"], "description"=>"<p>“Approval” column designates whether the study was submitted as part of the original approval submission to the FDA or whether it was conducted following FDA approval in 1991 or later. Drug benefit denotes the effect size for paroxetine compared to placebo.</p><p>Baseline scores, mean change, standardized mean change, and sample sizes for all studies reporting change on the Hamilton Rating Scale for Depression.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153272, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.t004", "stats"=>{"downloads"=>6, "page_views"=>18, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_scores_mean_change_standardized_mean_change_and_sample_sizes_for_all_studies_reporting_change_on_the_Hamilton_Rating_Scale_for_Depression_/1153272", "title"=>"Baseline scores, mean change, standardized mean change, and sample sizes for all studies reporting change on the Hamilton Rating Scale for Depression.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652279", "https://ndownloader.figshare.com/files/1652281", "https://ndownloader.figshare.com/files/1652282", "https://ndownloader.figshare.com/files/1652283", "https://ndownloader.figshare.com/files/1652286"], "description"=>"<div><p>Background</p><p>Previous meta-analyses of published and unpublished trials indicate that antidepressants provide modest benefits compared to placebo in the treatment of depression; some have argued that these benefits are not clinically significant. However, these meta-analyses were based only on trials submitted for the initial FDA approval of the medication and were limited to those aimed at treating depression. Here, for the first time, we assess the efficacy of a selective serotonin reuptake inhibitor (SSRI) in the treatment of both anxiety and depression, using a complete data set of all published and unpublished trials sponsored by the manufacturer.</p><p>Methods and Findings</p><p>GlaxoSmithKline has been required to post the results for all sponsored clinical trials online, providing an opportunity to assess the efficacy of an SSRI (paroxetine) with a complete data set of all trials conducted. We examined the data from all placebo-controlled, double-blind trials of paroxetine that included change scores on the Hamilton Rating Scale for Anxiety (HRSA) and/or the Hamilton Rating Scale for Depression (HRSD). For the treatment of anxiety (<i>k</i> = 12), the efficacy difference between paroxetine and placebo was modest (<i>d</i> = 0.27), and independent of baseline severity of anxiety. Overall change in placebo-treated individuals replicated 79% of the magnitude of paroxetine response. Efficacy was superior for the treatment of panic disorder (<i>d</i> = 0.36) than for generalized anxiety disorder (<i>d</i> = 0.20). Published trials showed significantly larger drug-placebo differences than unpublished trials (<i>d</i>’s = 0.32 and 0.17, respectively). In depression trials (<i>k</i> = 27), the benefit of paroxetine over placebo was consistent with previous meta-analyses of antidepressant efficacy (<i>d</i> = 0.32).</p><p>Conclusions</p><p>The available empirical evidence indicates that paroxetine provides only a modest advantage over placebo in treatment of anxiety and depression. Treatment implications are discussed.</p></div>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153350, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0106337.s001", "https://dx.doi.org/10.1371/journal.pone.0106337.s002", "https://dx.doi.org/10.1371/journal.pone.0106337.s003", "https://dx.doi.org/10.1371/journal.pone.0106337.s004", "https://dx.doi.org/10.1371/journal.pone.0106337.s005"], "stats"=>{"downloads"=>13, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_Efficacy_of_Paroxetine_and_Placebo_in_Treating_Anxiety_and_Depression_A_Meta_Analysis_of_Change_on_the_Hamilton_Rating_Scales_/1153350", "title"=>"The Efficacy of Paroxetine and Placebo in Treating Anxiety and Depression: A Meta-Analysis of Change on the Hamilton Rating Scales", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2014-08-27 03:01:01"}
• {"files"=>["https://ndownloader.figshare.com/files/1652186"], "description"=>"<p>GAD = generalized anxiety disorder. Drug benefit denotes the effect size for paroxetine compared to placebo.</p><p>Baseline scores, mean change, standardized mean change, and sample sizes for all studies reporting change on the Hamilton Rating Scale for Anxiety.</p>", "links"=>[], "tags"=>["serotonin reuptake inhibitor", "treatment implications", "ssri", "baseline severity", "Hamilton Rating Scale", "paroxetine response", "anxiety disorder", "FDA Approval", "change scores", "efficacy difference", "panic disorder", "HRSA", "antidepressant efficacy", "HRSD", "placebo", "depression trials"], "article_id"=>1153266, "categories"=>["Biological Sciences"], "users"=>["Michael A. Sugarman", "Amy M. Loree", "Boris B. Baltes", "Emily R. Grekin", "Irving Kirsch"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0106337.t002", "stats"=>{"downloads"=>1, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_scores_mean_change_standardized_mean_change_and_sample_sizes_for_all_studies_reporting_change_on_the_Hamilton_Rating_Scale_for_Anxiety_/1153266", "title"=>"Baseline scores, mean change, standardized mean change, and sample sizes for all studies reporting change on the Hamilton Rating Scale for Anxiety.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-08-27 03:01:01"}

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Relative Metric

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F1000Prime