The Effects of Cold Exposure on Leukocytes, Hormones and Cytokines during Acute Exercise in Humans
- Publication Date
- October 22, 2014
- Journal
- PLOS ONE
- Authors
- Dominique D. Gagnon, Sheila S. Gagnon, Hannu Rintamäki, Timo Törmäkangas, et al
- Volume
- 9
- Issue
- 10
- Pages
- e110774
- DOI
- https://dx.plos.org/10.1371/journal.pone.0110774
- Publisher URL
- http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0110774
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/25338085
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206434
- Europe PMC
- http://europepmc.org/abstract/MED/25338085
- Web of Science
- 000343674800075
- Scopus
- 84908461845
- Mendeley
- http://www.mendeley.com/research/effects-cold-exposure-leukocytes-hormones-cytokines-during-acute-exercise-humans
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Mendeley | Further Information
{"title"=>"The effects of cold exposure on leukocytes, hormones and cytokines during acute exercise in humans", "type"=>"journal", "authors"=>[{"first_name"=>"Dominique D.", "last_name"=>"Gagnon", "scopus_author_id"=>"54899833500"}, {"first_name"=>"Sheila S.", "last_name"=>"Gagnon", "scopus_author_id"=>"55880317600"}, {"first_name"=>"Hannu", "last_name"=>"Rintamäki", "scopus_author_id"=>"35576428400"}, {"first_name"=>"Timo", "last_name"=>"Törmäkangas", "scopus_author_id"=>"6506099905"}, {"first_name"=>"Katri", "last_name"=>"Puukka", "scopus_author_id"=>"9249785300"}, {"first_name"=>"Karl Heinz", "last_name"=>"Herzig", "scopus_author_id"=>"7007026450"}, {"first_name"=>"Heikki", "last_name"=>"Kyröläinen", "scopus_author_id"=>"7004076159"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"600234722", "issn"=>"19326203", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "doi"=>"10.1371/journal.pone.0110774", "scopus"=>"2-s2.0-84908461845", "pmid"=>"25338085", "sgr"=>"84908461845"}, "id"=>"1d93097c-e733-3d4b-b549-6cee1e262661", "abstract"=>"The purpose of the study was to examine the effects of exercise on total leukocyte count and subsets, as well as hormone and cytokine responses in a thermoneutral and cold environment, with and without an individualized pre-cooling protocol inducing low-intensity shivering. Nine healthy young men participated in six experimental trials wearing shorts and t-shirts. Participants exercised for 60 min on a treadmill at low (LOW: 50% of peak VO2) and moderate (MOD: 70% VO2peak) exercise intensities in a climatic chamber set at 22degreeC (NT), and in 0degreeC (COLD) with and without a pre-exercise low-intensity shivering protocol (SHIV). Core and skin temperature, heart rate and oxygen consumption were collected continuously. Blood samples were collected before and at the end of exercise to assess endocrine and immunological changes. Core temperature in NT was greater than COLD and SHIV by 0.4+/-0.2degreeC whereas skin temperature in NT was also greater than COLD and SHIV by 8.5+/-1.4degreeC and 9.3+/-2.5degreeC respectively in MOD. Total testosterone, adenocorticotropin and cortisol were greater in NT vs. COLD and SHIV in MOD. Norepinephrine was greater in NT vs. other conditions across intensities. Interleukin-2, IL-5, IL-7, IL-10, IL-17, IFN-gamma, Rantes, Eotaxin, IP-10, MIP-1beta, MCP-1, VEGF, PDGF, and G-CSF were elevated in NT vs. COLD and/or SHIV. Furthermore, IFN-gamma, MIP-1beta, MCP-1, IL-10, VEGF, and PDGF demonstrate greater concentrations in SHIV vs. COLD, mainly in the MOD condition. This study demonstrated that exercising in the cold can diminish the exercise-induced systemic inflammatory response seen in a thermoneutral environment. Nonetheless, prolonged cooling inducing shivering thermogenesis prior to exercise, may induce an immuno-stimulatory response following moderate intensity exercise. Performing exercise in cold environments can be a useful strategy in partially inhibiting the acute systemic inflammatory response from exercise but oppositely, additional body cooling may reverse this benefit.", "link"=>"http://www.mendeley.com/research/effects-cold-exposure-leukocytes-hormones-cytokines-during-acute-exercise-humans", "reader_count"=>42, "reader_count_by_academic_status"=>{"Unspecified"=>4, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>2, "Researcher"=>4, "Student > Ph. D. Student"=>5, "Student > Postgraduate"=>3, "Student > Master"=>15, "Other"=>1, "Student > Bachelor"=>3, "Lecturer"=>3, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>4, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>2, "Researcher"=>4, "Student > Ph. D. Student"=>5, "Student > Postgraduate"=>3, "Student > Master"=>15, "Other"=>1, "Student > Bachelor"=>3, "Lecturer"=>3, "Professor"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>2, "Unspecified"=>5, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>2, "Agricultural and Biological Sciences"=>4, "Medicine and Dentistry"=>5, "Neuroscience"=>2, "Sports and Recreations"=>15, "Psychology"=>3, "Immunology and Microbiology"=>3}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>2}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>5}, "Neuroscience"=>{"Neuroscience"=>2}, "Sports and Recreations"=>{"Sports and Recreations"=>15}, "Psychology"=>{"Psychology"=>3}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>4}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>5}, "Environmental Science"=>{"Environmental Science"=>1}}, "reader_count_by_country"=>{"Brazil"=>1, "Italy"=>1}, "group_count"=>2}CrossRef
- http://doi.org/10.1289/EHP5153
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- http://doi.org/10.1080/21635781.2018.1526145
- http://doi.org/10.14814/phy2.12394
- http://doi.org/10.1016/j.jsams.2018.05.014
- http://doi.org/10.1371/journal.pone.0137567
- http://doi.org/10.1038/s41598-019-39561-z
- http://doi.org/10.1371/journal.pone.0161749
- http://doi.org/10.1016/j.scitotenv.2017.10.208
- http://doi.org/10.1016/j.cyto.2018.12.006
- http://doi.org/10.3892/br.2016.730
Scopus | Further Information
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- {"referral"=>"http://www.runnersworld.com/cold-weather-running/how-running-in-the-cold-affects-your-immune-system?page=single", "language"=>"English", "title"=>"How Running in the Cold Affects Your Immune System | Runner's World & Running Times", "type"=>"News", "publication"=>"", "published_on"=>"", "link_state"=>""}
- {"referral"=>"http://www.runnersworld.co.uk/health/how-running-in-the-cold-affects-your-immune-system/12411.html", "language"=>"English", "title"=>"How running in the cold affects your immune system - Health - Runner's World", "type"=>"News", "publication"=>"", "published_on"=>"", "link_state"=>""}
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- {"id"=>"525178926205644800", "text"=>"寒いところで運動したら、運動による炎症反応が低下する。けど、運動前に長時間寒い所にいると中程度の運動で免疫反応が亢進する。間違っているかも。The Effects of Cold Exposure on Leukocytes, … http://t.co/jHGNdOX2NE", "created_at"=>"2014-10-23T06:56:28Z", "user"=>"uranus_2", "user_name"=>"マーキュリー2世", "user_profile_image"=>"http://pbs.twimg.com/profile_images/520761051646676992/x2e9wBQE_normal.png"}
- {"id"=>"526046922189312000", "text"=>"@microBEnet How temp while running modulates immune system http://t.co/aWlBlm4rje; glad @SloanFoundation is funding track athlete microbiome", "created_at"=>"2014-10-25T16:25:34Z", "user"=>"RBCCRC", "user_name"=>"Brian Klein", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2004191070/twitter_life_normal.jpg"}
- {"id"=>"526554591178276864", "text"=>"\"Exercise in cold can partially inhibit systemic inflammatory response but additional body cooling may reverse this\" http://t.co/6UPNDa9m42", "created_at"=>"2014-10-27T02:02:52Z", "user"=>"SeeSpondyRun", "user_name"=>"Adrienne", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000696821801/6c7d469c8d66bfa73a4529c353e220c7_normal.jpeg"}
- {"id"=>"526555893895528448", "text"=>"RT @SeeSpondyRun: \"Exercise in cold can partially inhibit systemic inflammatory response but additional body cooling may reverse this\" http…", "created_at"=>"2014-10-27T02:08:02Z", "user"=>"kstrbrennan", "user_name"=>"AFAP™ BK", "user_profile_image"=>"http://pbs.twimg.com/profile_images/519903527280582656/P6gr_eAU_normal.jpeg"}
- {"id"=>"527082001594339328", "text"=>"Interesting paper on #exercise & cold. #inflammation. Cold doesn't appear to be \"good\"\n\nhttp://t.co/QMJ0vYlHcN", "created_at"=>"2014-10-28T12:58:36Z", "user"=>"tyrrendure", "user_name"=>"Dan Tyrrell", "user_profile_image"=>"http://pbs.twimg.com/profile_images/502800423804096512/Nv1WuZBK_normal.jpeg"}
- {"id"=>"534362939399356416", "text"=>"@JWLevitt @NanasforBalance Along the same lines- this study: how running in the cold affects your immune system http://t.co/uwGv5hfb1W", "created_at"=>"2014-11-17T15:10:27Z", "user"=>"cmariepower", "user_name"=>"Christine Power", "user_profile_image"=>"http://pbs.twimg.com/profile_images/453893946734018560/G34aR-Zh_normal.jpeg"}
- {"id"=>"534362981971525632", "text"=>"RT @cmariepower: @JWLevitt @NanasforBalance Along the same lines- this study: how running in the cold affects your immune system http://t.c…", "created_at"=>"2014-11-17T15:10:37Z", "user"=>"JWLevitt", "user_name"=>"Jonathan Levitt", "user_profile_image"=>"http://pbs.twimg.com/profile_images/511564197214556160/Mrf_Lswc_normal.jpeg"}
- {"id"=>"543482496768544768", "text"=>"Open access! The Effects of Cold Exposure on Leukocytes, Hormones and Cytokines during Acute Exercise: http://t.co/4icFCBMQrR by @plosone", "created_at"=>"2014-12-12T19:08:19Z", "user"=>"Luminex", "user_name"=>"Luminex", "user_profile_image"=>"http://pbs.twimg.com/profile_images/3498697136/662ffecf7f6dd3118304980e2e64cae6_normal.png"}
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Relative Metric
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