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Compass: Clinical Evaluation of a New Instrument for the Diagnosis of Glaucoma

Publication Date: March 25, 2015
Journal: PLOS ONE
Authors: Luca Rossetti, Maurizio Digiuni, Alberto Rosso, Roberta Riva, et al
Volume: 10
Issue: 3
Pages: e0122157
DOI: https://dx.plos.org/10.1371/journal.pone.0122157
Publisher URL: http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0122157
PubMed: http://www.ncbi.nlm.nih.gov/pubmed/25807241
PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373771
Europe PMC: http://europepmc.org/abstract/MED/25807241
Web of Science: 000351880000207
Scopus: 84926304080
Mendeley: http://www.mendeley.com/research/compass-clinical-evaluation-new-instrument-diagnosis-glaucoma

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CiteULike29 Apr 10:27 UTC

CiteULike

Mendeley 1024 Apr 18:08 UTC

Mendeley | Further Information

{"title"=>"Compass: Clinical evaluation of a new instrument for the diagnosis of glaucoma", "type"=>"journal", "authors"=>[{"first_name"=>"Luca", "last_name"=>"Rossetti", "scopus_author_id"=>"57078136300"}, {"first_name"=>"Maurizio", "last_name"=>"Digiuni", "scopus_author_id"=>"55115693000"}, {"first_name"=>"Alberto", "last_name"=>"Rosso", "scopus_author_id"=>"56581527400"}, {"first_name"=>"Roberta", "last_name"=>"Riva", "scopus_author_id"=>"56581461200"}, {"first_name"=>"Giuliano", "last_name"=>"Barbaro", "scopus_author_id"=>"56581563800"}, {"first_name"=>"Michael K.", "last_name"=>"Smolek", "scopus_author_id"=>"6701857497"}, {"first_name"=>"Nicola", "last_name"=>"Orzalesi", "scopus_author_id"=>"56978225300"}, {"first_name"=>"Stefano", "last_name"=>"De Cilla", "scopus_author_id"=>"6506022938"}, {"first_name"=>"Alessandro", "last_name"=>"Autelitano", "scopus_author_id"=>"6602228953"}, {"first_name"=>"Paolo", "last_name"=>"Fogagnolo", "scopus_author_id"=>"6506256494"}], "year"=>2015, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"25807241", "sgr"=>"84926304080", "scopus"=>"2-s2.0-84926304080", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "doi"=>"10.1371/journal.pone.0122157", "pui"=>"603466366", "issn"=>"19326203"}, "id"=>"2b84b399-d99b-3b5f-9d2d-f2fe220d5a44", "abstract"=>"AIMS: To evaluate Compass, a new instrument for glaucoma screening and diagnosis that combines scanning ophthalmoscopy, automated perimetry, and eye tracking.\\n\\nMATERIALS AND METHODS: A total of 320 human subjects (200 normal, 120 with glaucoma) underwent full ophthalmological evaluation and perimetric evaluation using the Humphrey SITA standard 24° test (HFA), and the Compass test that consisted of a full-threshold program on the central 24° with a photograph of the central 30° of the retina. A subgroup of normal subjects and glaucoma patients underwent a second Compass test during the same day in order to study test-retest variability. After exclusion of 30 patients due to protocol rules, a database was created to compare the Compass to the HFA, and to evaluate retinal image quality and fixation stability.\\n\\nRESULTS: The difference in mean sensitivity between Compass and HFA was -1.02 ± 1.55 dB in normal subjects (p<0.001) and -1.01 ± 2.81 dB in glaucoma (p<0.001). Repeatability SD for the average sensitivity was 1.53 for normal subjects and 1.84 for glaucoma. Test time with the Compass was 634±96 s (607±78 for normals, 678±108 for glaucoma). Compass analysis showed the percentage of fixation within the central 1° was 86.6% in normal subjects, and 79.3% in glaucoma patients. Color image quality was sufficient for diagnostic use in >65% of cases; Image-based diagnosis was in accordance with the initial diagnosis in 85% of the subjects.\\n\\nCONCLUSIONS: Based on preliminary results, Compass showed useful diagnostic characteristics for the study of glaucoma, and combined morphological information with functional data.", "link"=>"http://www.mendeley.com/research/compass-clinical-evaluation-new-instrument-diagnosis-glaucoma", "reader_count"=>10, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>2, "Librarian"=>1, "Researcher"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>2, "Student > Master"=>2, "Other"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>2, "Librarian"=>1, "Researcher"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>2, "Student > Master"=>2, "Other"=>1}, "reader_count_by_subject_area"=>{"Medicine and Dentistry"=>6, "Agricultural and Biological Sciences"=>1, "Business, Management and Accounting"=>1, "Computer Science"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>6}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Computer Science"=>{"Computer Science"=>2}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}}, "group_count"=>0}

ORCID29 Apr 17:28 UTC

Scopus | Further Information

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Web of Science®24 Jul 03:40 UTC

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Journal Comments27 Oct 13:05 UTC

{"id"=>"822915301385728000", "text"=>"https://t.co/PfdVJFUISA #Compass is now available with #ZEST strategy for a 4 min #VisualField test", "created_at"=>"2017-01-21T21:14:31Z", "user"=>"CenterVue", "user_name"=>"CenterVue", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000729781218/e275f3edc94d976380c2abe3e8389aa0_normal.jpeg"}

Wikipedia15 Mar 22:11 UTC

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Figshare 9830 Apr 06:37 UTC

Figshare

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PMC Usage Stats 163717 Jul 20:28 UTC

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