Mendeley | Further Information

{"title"=>"Management of Prematurity-Associated Wheeze and Its Association with Atopy", "type"=>"journal", "authors"=>[{"first_name"=>"Martin O.", "last_name"=>"Edwards", "scopus_author_id"=>"56662418800"}, {"first_name"=>"Sarah J.", "last_name"=>"Kotecha", "scopus_author_id"=>"36089962400"}, {"first_name"=>"John", "last_name"=>"Lowe", "scopus_author_id"=>"55653359400"}, {"first_name"=>"Louise", "last_name"=>"Richards", "scopus_author_id"=>"56693991900"}, {"first_name"=>"W. John", "last_name"=>"Watkins", "scopus_author_id"=>"36090314000"}, {"first_name"=>"Sailesh", "last_name"=>"Kotecha", "scopus_author_id"=>"7003273921"}], "year"=>2016, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"610470907", "pmid"=>"27203564", "doi"=>"10.1371/journal.pone.0155695", "isbn"=>"1932-6203", "scopus"=>"2-s2.0-84971350771", "sgr"=>"84971350771", "issn"=>"19326203"}, "id"=>"26430362-d8db-3598-8c46-f2fc42fea5ce", "abstract"=>"INTRODUCTION: Although preterm birth is associated with respiratory morbidity in childhood, the role of family history of atopy and whether appropriate treatment has been instituted is unclear. Thus we assessed (i) the prevalence of respiratory symptoms, particularly wheezing, in childhood; (ii) evaluated the role of family history of atopy and mode of delivery, and (iii) documented the drug usage, all in preterm-born children compared to term-born control children. METHODS: We conducted a cross-sectional population-based questionnaire study of 1-10 year-old preterm-born children (n = 13,361) and matched term-born controls (13,361). Data (n = 7,149) was analysed by gestational groups (24-32 weeks, 33-34 weeks, 35-36 weeks and 37-43 weeks) and by age, <5 years old or >/= 5 years. MAIN RESULTS: Preterm born children aged <5 years (n = 2,111, term n = 1,402) had higher rates of wheeze-ever [odds ratio: 2.7 (95% confidence intervals 2.2, 3.3); 1.8 (1.5, 2.2); 1.5 (1.3, 1.8) respectively for the 24-32 weeks, 33-34 weeks, 35-36 weeks groups compared to term]. Similarly for the >/=5 year age group (n = 2,083, term n = 1,456) wheezing increased with increasing prematurity [odds ratios 3.3 (2.7, 4.1), 1.8 (1.5, 2.3) and 1.6 (1.3, 1.9) for the three preterm groups compared to term]. At both age groups, inhaler usage was greater in the lowest preterm group but prematurity-associated wheeze was independent of a family history of atopy. CONCLUSIONS: Increasing prematurity was associated with increased respiratory symptoms, which were independent of a family history of atopy. Use of bronchodilators was also increased in the preterm groups but its efficacy needs careful evaluation.", "link"=>"http://www.mendeley.com/research/management-prematurityassociated-wheeze-association-atopy", "reader_count"=>14, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Researcher"=>5, "Student > Doctoral Student"=>2, "Student > Master"=>4, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Researcher"=>5, "Student > Doctoral Student"=>2, "Student > Master"=>4, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Nursing and Health Professions"=>2, "Biochemistry, Genetics and Molecular Biology"=>1, "Mathematics"=>2, "Medicine and Dentistry"=>6, "Sports and Recreations"=>1, "Psychology"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>6}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Psychology"=>{"Psychology"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Mathematics"=>{"Mathematics"=>2}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>0}

CrossRef

• http://doi.org/10.1002/ppul.23920
• http://doi.org/10.1080/20018525.2018.1487214
• http://doi.org/10.1093/aje/kwy268
• http://doi.org/10.1016/j.jpeds.2020.04.042
• http://doi.org/10.1016/j.rmclc.2018.02.002
• http://doi.org/10.1136/bmjopen-2020-041528
• http://doi.org/10.1038/s41372-018-0264-y
• http://doi.org/10.1111/pai.12957
• http://doi.org/10.1016/j.jpeds.2018.02.032
• http://doi.org/10.1186/s13223-019-0356-z
• http://doi.org/10.1002/ppul.24270
• http://doi.org/10.1183/20734735.017218
• http://doi.org/10.1002/ppul.24649
• http://doi.org/10.3390/jcm9103345
• http://doi.org/10.1016/j.resp.2019.06.006

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/5305810"], "description"=>"<p>Bars denote the percentage of children having ever wheezed who have a family history of atopy (white bars) or not (black bars) and for both gestational groups, preterm or term.</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396160, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.g002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Prevalence_of_ever_wheezing_for_the_whole_study_population_/3396160", "title"=>"Prevalence of ever wheezing for the whole study population.", "pos_in_sequence"=>3, "defined_type"=>1, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305882"], "description"=>"<p>Characteristics of responders <5 years of age according to gestational groups.</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396226, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Characteristics_of_responders_5_years_of_age_according_to_gestational_groups_/3396226", "title"=>"Characteristics of responders <5 years of age according to gestational groups.", "pos_in_sequence"=>5, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305780"], "description"=>"<p>Diagram showing return rates of completed questionnaires in the Respiratory and Neurological Outcomes of children born Preterm Study (RANOPS).</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396133, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.g001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Diagram_showing_return_rates_of_completed_questionnaires_in_the_Respiratory_and_Neurological_Outcomes_of_children_born_Preterm_Study_RANOPS_/3396133", "title"=>"Diagram showing return rates of completed questionnaires in the Respiratory and Neurological Outcomes of children born Preterm Study (RANOPS).", "pos_in_sequence"=>2, "defined_type"=>1, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305852"], "description"=>"<p>Bars denote the percentage of wheezy children being treated with inhalers who have a family history of atopy (white bars) or not (black bars) and for both gestational groups, preterm or term.</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396199, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.g003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Prevalence_of_inhaler_treatment_amongst_wheezing_children_/3396199", "title"=>"Prevalence of inhaler treatment amongst wheezing children.", "pos_in_sequence"=>4, "defined_type"=>1, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305921"], "description"=>"<p>Childhood wheezing, family history, inhaler use and hospital admissions for all children less than 5 years-of-age compared by gestational age (unadjusted OR).</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396265, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Childhood_wheezing_family_history_inhaler_use_and_hospital_admissions_for_all_children_less_than_5_years-of-age_compared_by_gestational_age_unadjusted_OR_/3396265", "title"=>"Childhood wheezing, family history, inhaler use and hospital admissions for all children less than 5 years-of-age compared by gestational age (unadjusted OR).", "pos_in_sequence"=>7, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5306032"], "description"=>"<p>Childhood wheezing, family history, inhaler use and hospital admissions for very preterm born children with or without CLD compared to full term (unadjusted OR).</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396334, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t006", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Childhood_wheezing_family_history_inhaler_use_and_hospital_admissions_for_very_preterm_born_children_with_or_without_CLD_compared_to_full_term_unadjusted_OR_/3396334", "title"=>"Childhood wheezing, family history, inhaler use and hospital admissions for very preterm born children with or without CLD compared to full term (unadjusted OR).", "pos_in_sequence"=>10, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305759"], "description"=>"<div><p>Introduction</p><p>Although preterm birth is associated with respiratory morbidity in childhood, the role of family history of atopy and whether appropriate treatment has been instituted is unclear. Thus we assessed (i) the prevalence of respiratory symptoms, particularly wheezing, in childhood; (ii) evaluated the role of family history of atopy and mode of delivery, and (iii) documented the drug usage, all in preterm-born children compared to term-born control children.</p><p>Methods</p><p>We conducted a cross-sectional population-based questionnaire study of 1–10 year-old preterm-born children (n = 13,361) and matched term-born controls (13,361). Data (n = 7,149) was analysed by gestational groups (24–32 weeks, 33–34 weeks, 35–36 weeks and 37–43 weeks) and by age, <5 years old or ≥ 5 years.</p><p>Main Results</p><p>Preterm born children aged <5 years (n = 2,111, term n = 1,402) had higher rates of wheeze-ever [odds ratio: 2.7 (95% confidence intervals 2.2, 3.3); 1.8 (1.5, 2.2); 1.5 (1.3, 1.8) respectively for the 24–32 weeks, 33–34 weeks, 35–36 weeks groups compared to term]. Similarly for the ≥5 year age group (n = 2,083, term n = 1,456) wheezing increased with increasing prematurity [odds ratios 3.3 (2.7, 4.1), 1.8 (1.5, 2.3) and 1.6 (1.3, 1.9) for the three preterm groups compared to term]. At both age groups, inhaler usage was greater in the lowest preterm group but prematurity-associated wheeze was independent of a family history of atopy.</p><p>Conclusions</p><p>Increasing prematurity was associated with increased respiratory symptoms, which were independent of a family history of atopy. Use of bronchodilators was also increased in the preterm groups but its efficacy needs careful evaluation.</p></div>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396115, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695", "stats"=>{"downloads"=>2, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Management_of_Prematurity-Associated_Wheeze_and_Its_Association_with_Atopy/3396115", "title"=>"Management of Prematurity-Associated Wheeze and Its Association with Atopy", "pos_in_sequence"=>1, "defined_type"=>6, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305903"], "description"=>"<p>Characteristics of responders’ ≥5 years of age according to gestational groups.</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396247, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Characteristics_of_responders_5_years_of_age_according_to_gestational_groups_/3396247", "title"=>"Characteristics of responders’ ≥5 years of age according to gestational groups.", "pos_in_sequence"=>6, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5305942"], "description"=>"<p>Childhood wheezing, family history, inhaler use and hospital admissions for all children 5 years-of-age and older compared by gestational age (unadjusted OR).</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396286, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Childhood_wheezing_family_history_inhaler_use_and_hospital_admissions_for_all_children_5_years-of-age_and_older_compared_by_gestational_age_unadjusted_OR_/3396286", "title"=>"Childhood wheezing, family history, inhaler use and hospital admissions for all children 5 years-of-age and older compared by gestational age (unadjusted OR).", "pos_in_sequence"=>8, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}
• {"files"=>["https://ndownloader.figshare.com/files/5306005"], "description"=>"<p>The influence of family history of atopy on wheezing children being treated with inhalers by comparing preterm to term-born participants for both age groups.</p>", "links"=>[], "tags"=>["family history", "atopy", "preterm groups", "Main Results Preterm"], "article_id"=>3396319, "categories"=>["Medicine", "Cell Biology", "Biotechnology", "Developmental Biology", "Cancer", "Science Policy", "Infectious Diseases", "Virology"], "users"=>["Martin O. Edwards", "Sarah J. Kotecha", "John Lowe", "Louise Richards", "W. John Watkins", "Sailesh Kotecha"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0155695.t005", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_influence_of_family_history_of_atopy_on_wheezing_children_being_treated_with_inhalers_by_comparing_preterm_to_term-born_participants_for_both_age_groups_/3396319", "title"=>"The influence of family history of atopy on wheezing children being treated with inhalers by comparing preterm to term-born participants for both age groups.", "pos_in_sequence"=>9, "defined_type"=>3, "published_date"=>"2016-05-20 05:25:23"}

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F1000Prime